Principles of periodontology

Periodontology 2000

Volumn 61, Issue 1, 2013, Pages 16-53

  Dentino, Andrew ^a   Lee, Seokwoo ^a   Mailhot, Jason ^a   Hefti, Arthur F ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOFILM; DISEASES; HOST PATHOGEN INTERACTION; HUMAN; METHODOLOGY; MICROBIOLOGY; MULTIMODALITY CANCER THERAPY; PERIODONTAL DISEASE; PERIODONTICS; RISK FACTOR; TISSUE ENGINEERING;

BIOFILMS; COMBINED MODALITY THERAPY; DISEASE; GUIDED TISSUE REGENERATION, PERIODONTAL; HOST-PATHOGEN INTERACTIONS; HUMANS; PERIODONTAL DISEASES; RISK FACTORS; TISSUE ENGINEERING;

EID: 84865361411     PISSN: 09066713     EISSN: 16000757     Source Type: Journal    
DOI: 10.1111/j.1600-0757.2011.00397.x     Document Type: Article

References (429)

1. American Academy of Periodontology. Committee Report and Discussion. The Etiology of Periodontal Disease. In: World Workshop in Periodontics (Proceedings). Chicago, IL: American Academy of Periodontology, 1966: 167-177.
2. American Academy of Periodontology. Consensus Report. In: Nevins M, Becker W, Kornman K, editors. Proceedings of the World Workshop in Clinical Periodontics. Chicago, IL: American Academy of Periodontology. 1989:I/23-I/24
3. American Academy of Periodontology. Position paper. Supportive periodontal therapy (SPT). J Periodontol 1998: 69: 502-506.
4. American Academy of Periodontology. Consensus report. Necrotizing periodontal diseases. Ann Periodontol 1999: 4: 78.
5. American Academy of Periodontology. Parameters of care. Parameter on occlusal traumatism in patients with chronic periodontitis. J Periodontol 2000: 71: 873-875.
6. American Academy of Periodontology. Glossary of Periodontal Terms, 4th edition. Chicago, IL: American Academy of Periodontology, 2001.
7. American Academy of Periodontology. Academy report/Informational paper. Drug-associated gingival enlargement. J Periodontol 2004: 75: 1424-1431.
8. American Academy of Periodontology. Position paper. Systemic antibiotics in periodontics. J Periodontol 2004: 75: 1553-1565.
9. American Academy of Periodontology. Position paper. Periodontal regeneration. J Periodontol 2005: 76: 1601-1622.
10. American Academy of Periodontology. Academy report. Implications of genetic technology for the management of periodontal diseases. J Periodontol 2005: 76: 850-857.
11. American Academy of Periodontology. Local delivery of sustained or controlled release antimicrobials as adjunctive therapy for the treatment of periodontitis. J Periodontol 2006: 77: 1458.
12. Aas JA, Paster BJ, Stokes LN, Olsen I, Dewhirst FE. Defining the normal bacterial flora of the oral cavity. J Clin Microbiol 2005: 43: 5721-5732.
13. Africa CW, Parker JR, Reddy J. Bacteriological studies of subgingival plaque in a periodontitis-resistant population. J Periodontal Res 1985: 20: 1-7.
14. Agrawal S, Agrawal A, Doughty B, Gerwitz A, Blenis J, van Dyke T, Pulendran B. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J Immunol 2003: 171: 4984-4989.
15. Albandar JM, Baghdady VS, Ghose LJ. Periodontal disease progression in teenagers with no preventive dental care provisions. J Clin Periodontol 1991: 18: 341-345.
16. Albandar JM, Brown LJ, Löe H. Clinical features of early-onset periodontitis. J Am Dent Assoc 1997: 128: 1393-1399.
17. Albandar JM, Streckfus CF, Adesanya MR, Winn DM. Cigar, pipe, and cigarette smoking as risk factors for periodontal disease and tooth loss. J Periodontol 2000: 71: 1874-1881.
18. Albandar JM, Muranga MB, Rams TE. Prevalence of aggressive periodontitis in shool attendees in Uganda. J Clin Periodontol 2002: 29: 823-831.
19. Albandar JM, Rams TE. Global epidemiology of periodontal diseases: an overview. Periodontol 2000 2002: 29: 7-245.
20. Albandar JM, Tinoco EMB. Global epidemiology of periodontal diseases in children and young persons. Periodontol 2000 2002: 29: 153-176.
21. Allen EP, Miller PD Jr. Coronal positioning of existing gingiva: short-term results in treatment of shallow marginal tissue recession. J Periodontol 1989: 60: 316-319.
22. Ambrosini P, Miller N, Briançon S, Gallina S, Penaud J. Clinical and microbiological evaluation of the effectiveness of the Nd:Yap laser for the initial treatment of adult periodontitis. A randomized controlled study. J Clin Periodontol 2005: 32: 670-676.
23. Andersen R, Loebel N, Hammond D, Wilson M. Treatment of periodontal disease by photodisinfection compared to scaling and root planing. J Clin Dent 2007: 18: 34-38.
24. Andia DC, Martins AG, Casati MZ, Sallum EA, Nociti FH. Root coverage outcome may be affected by heavy smoking: a 2-year follow-up study. J Periodontol 2008: 79: 647-653.
25. Apatzidou DA, Kinane DF. Quadrant root planing versus same-day full-mouth root planing. I. Clinical findings. J Clin Periodontol 2004: 31: 132-140.
26. Apatzidou DA, Riggio MP, Kinane DF. Quadrant root planing versus same-day full-mouth root planing. II. Microbiological findings. J Clin Periodontol 2004: 31: 141-148.
27. Aranki A, Syed SA, Kenney EB, Freter R. Isolation of anaerobic bacteria from human gingival and mouse cecum by means of a simplified glove box procedure. Appl Microbiol 1969: 17: 568-576.
28. Arendorf TM, Bredekamp B, Cloete CA, Joshipura K. Seasonal variation of acute necrotizing ulcerative gingivitis in South Africans. Oral Dis 2001: 7: 150-154.
29. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999: 4: 1-6.
30. Armitage GC. Classifying periodontal diseases - a long-standing dilemma. Periodontol 2000 2002: 30: 9-23.
31. Arno A, Schei O, Lövdal A, Waerhaug J. Alveolar bone loss as a function of tobacco consumption. Acta Odontol Scand 1959: 17: 3-8.
32. Attström R, van der Velden U. Consensus report (epidemiology). In: Lang NP, Karring T, editors. Proceedings of the 1st European Workshop on Periodontics, 1993. London: Quintessence Publishing Co. Inc., 1994: 120-126.
33. Axelsson P, Lindhe J. Effect of controlled oral hygiene procedures on caries and periodontal disease in adults. J Clin Periodontol 1978: 5: 239-248.
34. Axelsson P, Lindhe J. Effect of controlled oral hygiene procedures on caries and periodontal disease in adults. Results after six years. J Clin Periodontol 1981: 8: 133-151.
35. Axelsson P, Lindhe J, Nyström B. On the prevention of caries and periodontal disease. Results of a 15-year longitudinal study in adults. J Clin Periodontol 1991: 18: 182-189.
36. Axelsson P, Paulander J, Lindhe J. Relationship between smoking and dental status in 35-, 50-, 65-, and 75-year-old individuals. J Clin Periodontol 1998: 25: 297-305.
37. Axelsson P, Albandar JM, Rams TE. Prevention and control of periodontal diseases in developing and industrialized nations. Periodontol 2000 2002: 29: 235-246.
38. Axelsson P, Nyström B, Lindhe J. The long-term effect of a plaque control program on tooth mortality, caries and periodontal disease in adults. Results after 30years of maintenance. J Clin Periodontol 2004: 31: 749-757.
39. Badersten A, Nilvéus R, Egelberg J. Effect of nonsurgical periodontal therapy. I. Moderately advanced periodontitis. J Clin Periodontol 1981: 8: 57-72.
40. Badersten A, Nilvéus R, Egelberg J. Effect of nonsurgical periodontal therapy. II. Severely advanced periodontitis. J Clin Periodontol 1984: 11: 63-76.
41. Badersten A, Nilvéus R, Egelberg J. Scores of plaque, bleeding, suppuration and probing depth to predict probing attachment loss. 5years of observation following nonsurgical periodontal therapy. J Clin Periodontol 1990: 17: 102-107.
42. Baehni P, Tsai CC, McArthur WP, Hammond BF, Taichman NS. Interaction of inflammatory cells and oral microorganisms. VIII. Detection of leukotoxic activity of a plaque-derived gram-negative microorganism. Infect Immun 1979: 24: 233-243.
43. Baelum V, Scheutz F. Periodontal diseases in Africa. Periodontol 2000 2002: 29: 79-103.
44. Baelum V, Lopez R. Defining and classifying periodontitis: need for a paradigm shift? Eur J Oral Sci 2003: 111: 2-6.
45. Baer PN. The case for periodontosis as a clinical entity. J Periodontol 1971: 42: 516-520.
46. Barbour SE, Nakashima K, Zhang JB, Tangada S, Hahn CL, Schenkein HA, Tew JG. Tobacco and smoking: environmental factors that modify the host response (immune system) and have an impact on periodontal health. Crit Rev Oral Biol Med 1997: 8: 437-460.
47. Bassler BL. How bacteria talk to each other: regulation of gene expression by quorum sensing. Curr Opin Microbiol 1999: 2: 582-587.
48. Becker W, Becker BE, Ochsenbein C, Kerry G, Caffesse R, Morrison EC, Prichard J. A longitudinal study comparing scaling, osseous surgery and modified Widman procedures after one year. J Periodontol 1988: 59: 351-365.
49. Bergström J. Tobacco smoking and chronic destructive periodontal disease. Odontology 2004: 92: 1-8.
50. Beuchat M, Busslinger A, Schmidlin PR, Michel B, Lehmann B, Lutz F. Clinical comparison of the effectiveness of novel sonic instruments and curettes for periodontal debridement after 2months. J Clin Periodontol 2001: 28: 1145-1150.
51. Billings F. Chronic focal infections and their etiologic relations to arthritis and nephritis. Arch Intern Med 1912: 9: 484-498.
52. Bonito AJ, Lux L, Lohr KN. Impact of local adjuncts to scaling and root planing in periodontal disease therapy: a systematic review. J Periodontol 2005: 76: 1227-1236.
53. Borrell LN, Burt BA, Taylor GW. Prevalence and trends in periodontitis in the USA: from the NHANES III to the NHANES, 1988 to 2000. J Dent Res 2005: 84: 924-930.
54. Bostanci N, Ilgenli T, Emingil G, Afacan B, Han B, Toz H, Atilla G, Hughes FJ, Belibasakis GN. Gingival crevicular fluid levels of RANKL & OPG in periodontal diseases: implications of their relative ratio. J Clin Periodontol 2007: 34: 370-376.
55. Bowers GM, Vargo JW, Levy B, Emerson JR, Bergquist JJ. Histologic observations following the placement of tricalcium phosphate implants in human intrabony defects. J Periodontol 1986: 57: 286-287.
56. Bowers GM, Chadroff B, Carnevale R, Mellonig J, Corio R, Emerson J, Stevens M, Romberg E. Histologic evaluation of new attachment apparatus formation in humans. Part I. J Periodontol 1989: 60: 664-674.
57. Brayer WK, Mellonig JT, Dunlap RM, Marinak KW, Carson RE. Scaling and root planing effectiveness: the effect of root surface access and operator experience. J Periodontol 1989: 60: 67-72.
58. Brett PM, Zygogianni P, Griffiths GS, Tomaz M, Parkar M, D'Aiuto F, Tonetti M. Functional gene polymorphisms in aggressive and chronic periodontitis. J Dent Res 2005: 84: 1149-1153.
59. Brewer JH, Allgeier DL. A safe self-contained carbon dioxide-hydrogen anaerobic system. Appl Microbiol 1966: 14: 985-988.
60. Brill N. Influence of capillary permeability on flow of tissue fluid into gingival pockets. Acta Odontol Scand 1959: 17: 23-33.
61. Buchanan SA, Robertson PB. Calculus removal by scaling/root planing with and without surgical access. J Periodontol 1987: 58: 159-163.
62. Caffesse RG, Sweeney PL, Smith BA. Scaling and root planing with and without periodontal flap surgery. J Clin Periodontol 1986: 13: 205-210.
63. Carranza F. Microbiology. In: Carranza F, Shklar G, editors. History of Periodontology. Chicago, IL: Quintessence Publishing Co. Inc., 2003: 80-91.
64. Caton JG, Ciancio SG, Blieden TM, Bradshaw M, Crout RJ, Hefti AF, Massaro JM, Polson AM, Thomas J, Walker C. Treatment with subantimicrobial dose doxycycline improves the efficacy of scaling and root planing in patients with adult periodontitis. J Periodontol 2000: 71: 521-532.
65. Cecil RL, Angevine DM. Clinical and experimental observations on focal infections with an analysis of 200 cases of rheumatoid arthritis. Ann Intern Med 1938: 12: 577-584.
66. Centers for Disease Control and Prevention. National Diabetes Fact Sheet. Atlanta, GA: Centers for Disease Control and Prevention, 2005.
67. Cercek JF, Kiger RD, Garrett S, Egelberg J. Relative effects of plaque control and instrumentation on the clinical parameters of human periodontal disease. J Clin Periodontol 1983: 10: 46-56.
68. Chambrone L, Sukekava F, Araujo MG, Pustiglioni FE, Chambrone LA, Lima LA. Root coverage procedures for the treatment of localised recession-type defects. Cochrane Database Syst Rev 2009: DOI: 0.1002/4651858.CD007161.pub2
69. Chapple ILC, Milward MR, Dietrich T. The prevalence of inflammatory periodontitis is negatively associated with serum antioxidant concentrations. J Nutr 2006: 137: 657-664.
70. Chapple ILC. Potential mechanisms underpinning the nutritional modulation of periodontal inflammation. J Am Dent Assoc 2009: 140: 178-184.
71. Choi BK, Paster BJ, Dewhirst FE, Göbel UB. Diversity of cultivable and uncultivable oral spirochetes from a patient with severe destructive periodontitis. Infect Immun 1994: 62: 1889-1895.
72. Christou V, Timmerman MF, van der Velden U, van der Weijden FA. Comparison of different approaches of interdental oral hygiene: interdental brushes versus dental floss. J Periodontol 1998: 69: 759-764.
73. Chung WO, Dommisch H, Yin L, Dale BA. Expression of defensins in gingival and their role in periodontal health and disease. Curr Pharm Des 2007: 13: 3073-3083.
74. Cianciola LJ, Genco RJ, Patters MR, McKenna J, van Oss CJ. Defective polymorphonuclear leukocyte function in a human periodontal disease. Nature 1977: 265: 445-447.
75. Claffey N, Nylund K, Kiger R, Garrett S, Egelberg J. Diagnostic predictability of scores of plaque, bleeding, suppuration and probing depth for probing attachment loss. 31/2 years of observation following initial periodontal therapy. J Clin Periodontol 1990: 17: 108-114.
76. Claffey N, Egelberg J. Clinical indicators of probing attachment loss following initial periodontal treatment in advanced periodontitis patients. J Clin Periodontol 1995: 22: 690-696.
77. Clark RA, Page RC, Wilde G. Defective neutrophil chemotaxis in juvenile periodontitis. Infect Immun 1977: 18: 694-700.
78. Clarridge JE III. Impact of 16S rRNA gene sequence analysis for identification of bacteria on clinical microbiology and infectious diseases. Clin Microbiol Rev 2004: 17: 840-862.
79. Clementini M, Vittorini G, Crea A, Gualano MR, Macrì LA, La Torre G. Efficacy of AZM therapy in patients with gingival overgrowth induced by cyclosporine A: a systematic review. BMC Oral Health 2008: 8: 34-40.
80. Cobb CM. Lasers in periodontics: a review of the literature. J Periodontol 2006: 77: 545-564.
81. Cohen RE, on behalf of the Research, Science and Therapy Committee, American Academy of Periodontology. Position paper: periodontal maintenance. J Periodontol 2003: 74: 1395-1401.
82. Collet-Schaub D. The prevalence of acute necrotizing ulcerative gingivitis in Swiss military collectives. Schweiz Monatsschr Zahnmed 2000: 110: 538-541.
83. Corbet EF, Zee KY, Lo ECM. Periodontal diseases in Asia and Oceania. Periodontol 2000 2002: 29: 122-152.
84. Corey LA, Nance WE, Hofstede P, Schenkein HA. Self-reported periodontal disease in a Virginia twin population. J Periodontol 1993: 64: 1205-1208.
85. Cortellini P, Prato GP, Tonetti MS. The modified papilla preservation technique. A new surgical approach for interproximal regenerative procedures. J Periodontol 1995: 66: 261-266.
86. Cortellini P, Prato GP, Tonetti MS. The simplified papilla preservation flap. A novel surgical approach for the management of soft tissues in regenerative procedures. Int J Periodontics Restorative Dent 1999: 19: 589-599.
87. Cosyn J, Sabzevar MM. A systematic review on the effects of subgingival chlorhexidine gel administration in the treatment of chronic periodontitis. J Periodontol 2005: 76: 1805-1813.
88. Cosyn J, Wyn I. A systematic review on the effects of the chlorhexidine chip when used as an adjunct to scaling and root planing in the treatment of chronic periodontitis. J Periodontol 2006: 77: 257-264.
89. Crane AB, Kaplan H. The technique and results of surgical pyorrhea treatment. Dental Digest 1932: 38: 3.
90. Crespi RP, Capparè P, Toscanelli I, Gherlone E, Romanos GE. Effects of Er:YAG laser compared to ultrasonic scaler in periodontal treatment: a 2-year follow-up split-mouth clinical study. J Periodontol 2007: 78: 1195-1200.
91. Czarnetzki A, Jakob T, Pusch CM. Palaeopathological and variant conditions of the Homo heidelbergensis type specimen (Mauer, Germany). J Hum Evol 2003: 44: 479-495.
92. D'Aiuto F, Parkar M, Tonetti MS. Acute effects of periodontal therapy on bio-markers of vascular health. J Clin Periodontol 2007: 34: 124-129.
93. Dale BA, Fredericks LP. Antimicrobial peptides in the oral environment: expression and function in health and disease. Curr Issues Mol Biol 2005: 7: 119-134.
94. Darré L, Vergnes JN, Gourdy P, Sixou M. Efficacy of periodontal treatment on glycemic control in diabetic patients: a meta-analysis of interventional studies. Diabetes Metab 2008: 34: 497-506.
95. Dasanayake AP. Poor periodontal health of the pregnant woman as a rsik factor for low birth weight. Ann Periodontol 1998: 3: 206-212.
96. Davé S, Van Dyke TE. The link between periodontal disease and cardiovascular disease is probably inflammation. Oral Dis 2008: 14: 95-101.
97. de Almeida JM, Theodoro LH, Bosco AF, Nagata MJ, Oshiiwa M, Garcia VG. In vivo effect of photodynamic therapy on periodontal bone loss in dental furcations. J Periodontol 2008: 79: 1081-1088.
98. De Iudicibus S, Castronovo G, Gigante A, Stocco G, Decorti G, Di Lenarda R, Bartoli F. Role of MDR1 gene polymorphisms in gingival overgrowth induced by cyclosporine in transplant patients. J Periodontal Res 2008: 43: 665-672.
99. De Lissovoy G, Rentz AM, Dukes EM, Eaton CA, Jeffcoat MK, Killoy WJ, Finkelman RD. The cost-effectiveness of a new chlorhexidine delivery system in the treatment of adult periodontitis. J Am Dent Assoc 1999: 130: 855-862.
100. Dentino AR, Kassab MM, Renner EJ. Prevention of periodontal diseases. Dent Clin North Am 2005: 49: 573-594.
101. DeRouen TA, Hujoel PP, Mancl LA. Concise review: statistical issues in periodontal research. J Dent Res 1995: 74: 1731-1737.
102. De Stefano F, Anda RF, Kahn HS, Williamson DF, Russell CM. Dental disease and risk of coronary heart disease and mortality. BMJ 1993: 306: 688-691.
103. DeVore CH, Duckworth JE, Beck FM, Hicks MJ, Brumfield FW, Horton JE. Bone loss following periodontal therapy in subjects without frequent periodontal maintenance. J Periodontol 1986: 57: 354-359.
104. Dolan TA, McGorray SP, Grinstead-Skigen CL, Mecklenburg R. Tobacco control activities in U.S. dental practices. J Am Dent Assoc 1997: 128: 1669-1679.
105. Donnenfeld OW, Glickman I. A biometric study of the effects of gingivectomy. J Periodontol 1966: 37: 447-452.
106. Dragoo MR. A clinical evaluation of hand and ultrasonic instruments on subgingival debridement. 1. With unmodified and modified ultrasonic inserts. Int J Periodontics Restorative Dent 1992: 12: 310-323.
107. Drisko CL, Cobb CM, Killoy WJ, Michalowicz BS, Pihlstrom BL, Lowenguth EA, Caton JG, Encarnaçion M, Knowles M, Goodson JM. Evaluation of periodontal treatments using controlled-release tetracycline fibers: clinical response. J Periodontol 1995: 66: 692-699.
108. Egelberg J. Permeability of the dento-gingival blood vessels. I. Application of the vascular labeling method and gingival fluid measurement. J Periodontal Res 1966: 1: 180-191.
109. Eickholz P, Kim TS, Bürklin T, Schacher B, Renggli HH, Schaecken MT, Holle R, Kübler A, Ratka-Krüger P. Non-surgical periodontal therapy with adjunctive topical doxycycline: a double-blind randomized controlled multicenter study. J Clin Periodontol 2002: 29: 108-117.
110. Emrich LJ, Shlossman M, Genco RJ. Periodontal disease in non-insulin-dependent diabetes mellitus. J Periodontol 1991: 62: 123-131.
111. Erley KJ, Swiec GD, Herold R, Bisch FC, Peacock ME. Gingival recession treatment with connective tissue grafts in smokers and non-smokers. J Periodontol 2006: 77: 1148-1155.
112. Esposito M, Grusovin MG, Coulthard P, Worthington HV. Enamel matrix derivative (Emdogain) for periodontal tissue regeneration in intrabony defects. Cochrane Database Syst Rev 2005: DOI: 10.1002/14651858.CD003875.pub3.
113. Fauchard P. Le Chirurgien Dentiste ou Traité Des Dents, Pierre-Jean Mariette, Paris, Volume I, 2nd edition, 1746: 105-117.
114. Ferreira SB Jr, Trombone AP, Repeke CE, Cardoso CR, Martins W Jr, Santos CF, Trevilatto PC, Avila-Campos MJ, Campanelli AP, Silva JS, Garlet GP. An interleukin-1β (IL-1β) single-nucleotide polymorphism at position 3954 and red complex periodontopathogens independently and additively modulate the levels of IL-1β in diseased periodontal tissues. Infect Immun 2008: 76: 3725-3734.
115. Fine DH, Kaplan JB, Kachlany SC, Schreiner HC. How we got attached to Actinobacillus actinomycetemcomitans: a model for infectious diseases. Periodontol 2000 2006: 42: 114-157.
116. Fleischer HC, Mellonig JT, Brayer WK, Gray JL, Barnett JD. Scaling and root planing efficacy in multirooted teeth. J Periodontol 1989: 60: 402-409.
117. Flemmig TF. Periodontitis. Ann Periodontol 1999: 4: 32-37.
118. Fourrier F, Duvivier B, Boutigny H, Roussel-Delvallez M, Chopin C. Colonization of the dental plaque: a source of nosocomial infections in intensive care unit patients. Crit Care Med 1998: 26: 301-308.
119. Friedman N. Periodontal osseous surgery: osteoplasty and osteoectomy. J Periodontol 1955: 26: 257-259.
120. Galicia JC, Tai H, Komatsu Y, Shimada Y, Ikezawa I, Yoshie H. Interleukin-6 receptor gene polymorphisms and periodontitis in a non-smoking Japanese population. J Clin Periodontol 2006: 33: 704-709.
121. Gasche C. Review article: the chemoprevention of colorectal carcinoma. Aliment Pharmacol Ther 2004: 20(Suppl.): 31-35.
122. Gaunt F, Devine M, Pennington M, Vernazza C, Gwynnett E, Steen N, Heasman P. The cost-effectiveness of supportive periodontal care for patients with chronic periodontitis. J Clin Periodontol 2008: 35: 67-82.
123. Giannobile WV, Finkelman RD, Lynch SE. Comparison of canine and non-human primate animal models for periodontal regenerative therapy: results following a single administration of PDGF/IGF-1. J Periodontol 1994: 65: 1158-1168.
124. Giannobile WV. Host-response therapeutics for periodontal diseases. J Periodontol 2008: 79(Suppl.): 1592-1600.
125. Glick M, Abel SN, Muzyka BC, DeLorenzo M. Dental complications after treating patients with AIDS. J Am Dent Assoc 1994: 125: 296-301.
126. Glickman I. Acute vitamin C deficiency and periodontal disease. I. The periodontal tissues of the guinea pig in acute vitamin C deficiency. J Dent Res 1948: 27: 9-23.
127. Gold SI. Periodontics. The past. Part (I). Early sources. J Clin Periodontol 1985: 12: 79-97.
128. Gold SI. Periodontics. The past. Part (II). The development of modern periodontics. J Clin Periodontol 1985: 12: 171-189.
129. Golub LM, Lee HM, Lehrer G, Nemiroff A, McNamara TF, Kaplan R, Ramamurthy NS. Minocycline reduces gingival collagenolytic activity during diabetes. Preliminary observations and a proposed new mechanism of action. J Periodontal Res 1983: 18: 516-526.
130. +3953 allele 2: association with disease status in adult periodontitis. J Clin Periodontol 1998: 25: 781-785.
131. Gottlow J, Nyman S, Karring T, Lindhe J. New attachment formation as the result of controlled tissue regeneration. J Clin Periodontol 1984: 11: 494-503.
132. Gottlow J, Nyman S, Lindhe J, Karring T, Wennström J. New attachment formation in the human periodontium by guided tissue regeneration. Case reports. J Clin Periodontol 1986: 13: 604-616.
133. Greenstein G. Efficacy of subantimicrobial-dose doxycycline in the treatment of periodontal diseases: a critical evaluation. Int J Periodontics Restorative Dent 2004: 24: 528-543.
134. Griffiths GS. Formation, collection and significance of gingival crevice fluid. Periodontol 2000 2003: 31: 32-42.
135. Grob GN. The rise and decline of tonsillectomy in twentieth-century America. J Hist Med Allied Sci 2007: 62: 383-421.
136. Grossi SG, Genco RJ, Machtei EE, Ho AW, Koch G, Dunford R, Zambon JJ, Hausmann E. Assessment of risk for periodontal disease. II. Risk indicators for alveolar bone loss. J Periodontol 1995: 66: 23-29.
137. Grossi SG, Skrepcinski FB, DeCaro T, Robertson DC, Ho AW, Dunford RG, Genco RJ. Treatment of periodontal disease in diabetics reduces glycated hemoglobin. J Periodontol 1997: 68: 713-719.
138. Grossi SG, Zambon J, Machtei EE, Schifferle R, Andreana S, Genco RJ, Cummins D, Harrap G. Effects of smoking cessation on healing after mechanical periodontal therapy. J Am Dent Assoc 1997: 128: 599-607.
139. Guerini V. A History of Dentistry from the Most Ancient Times until the End of the Eighteenth Century. Philadelphia/New York: Lea & Febiger, 1929: 19-31.
140. Gürsoy M, Pajukanta R, Sorsa T, Könönen E. Clinical changes in periodontium during pregnancy and post-partum. J Clin Periodontol 2008: 35: 576-583.
141. Haffajee AD, Socransky SS, Gunsolley JC. Systemic anti-infective periodontal therapy. A systematic review. Ann Periodontol 2003: 8: 115-181.
142. Haffajee AD, Torresyap G, Socransky SS. Clinical changes following four different periodontal therapies for the treatment of chronic periodontitis: 1-year results. J Clin Periodontol 2007: 34: 243-253.
143. Hamp SE, Nyman S, Lindhe J. Periodontal treatment of multirooted teeth. Results after 5years. J Clin Periodontol 1975: 2: 126-135.
144. Hanes PJ, Purvis JP. Local anti-infective therapy: pharmacological agents. A systematic review. Ann Periodontol 2003: 8: 79-98.
145. Hart TC, Atkinson JC. Mendelian forms of periodontitis. Periodontol 2000 2007: 45: 95-112.
146. Haslam DW, James WPT. Obesity. Lancet 2005: 366: 1197-1209.
147. Hassell TM, Hefti AF. Drug-induced gingival overgrowth: old problem, new problem. Crit Rev Oral Biol Med 1991: 2: 103-137.
148. Hasturk H, Kantarci A, Ohira T, Arita M, Ebrahimi N, Chiang N, Petasis NA, Levy BD, Serhan CN, van Dyke TE. RvE1 protects from local inflammation and osteoclast-mediated bone destruction in periodontitis. FASEB J 2006: 20: 401-403.
149. Haubek D, Ennibi OK, Poulsen K, Poulsen S, Benzarti N, Kilian M. Early-onset periodontitis in Morocco is associated with the highly leukotoxic clone of Actinobacillus actinomycetemcomitans. J Dent Res 2001: 80: 1580-1583.
150. Haubek D, Ennibi OK, Poulsen K, Vaeth M, Poulsen S, Kilian M. Risk of aggressive periodontitis in adolescent carriers of the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans in Morocco: a prospective longitudinal cohort study. Lancet 2008: 371: 237-242.
151. Hedley AA, Ogden CL, Johnson CL, Carroll MD, Curtin LR, Flegal KM. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. J Am Med Assoc 2004: 291: 2847-2850.
152. Hefti AF, Eshenaur AE, Hassell TM, Stone C. Gingival overgrowth in cyclosporineA-treated multiple sclerosis patients. J Periodontol 1994: 65: 744-749.
153. Heijl L, Heden G, Svärdström G, Ostgren A. Enamel matrix derivative (Emdogain) in the treatment of intrabony periodontal defects. J Clin Periodontol 1997: 24: 705-714.
154. Heitz-Mayfield LJ, Trombelli L, Heitz F, Needleman I, Moles D. A systematic review of the effect of surgical debridement vs non-surgical debridment for the treatment of chronic periodontitis. J Clin Periodontol 2002: 29(Suppl.): 92-102.
155. Heitz-Mayfield LJ. Disease progression: identification of high-risk groups and individuals for periodontitis. J Clin Periodontol 2005: 32: 196-209.
156. Helldén LB, Elliot A, Steffensen B, Steffensen JE. The prognosis of tunnel preparations in treatment of class III furcations. A follow-up study. J Periodontol 1989: 60: 182-187.
157. Henderson B, Nair SP, Ward JM, Wilson M. Molecular pathogenicity of the oral opportunistic pathogen Actinobacillus actinomycetemcomitans. Annu Rev Microbiol 2003: 57: 29-55.
158. Henke CJ, Villa KF, Aichelmann-Reidy ME, Armitage GC, Eber RM, Genco RJ, Killoy WJ, Miller DP, Page RC, Polson AM, Ryder MI, Silva SJ, Somerman MJ, Van Dyke TE, Wolff LF, Evans CJ, Finkelman RD. An economic evaluation of a chlorhexidine chip for treating chronic periodontitis: the CHIP (chlorhexidine in periodontitis) study. J Am Dent Assoc 2001: 132: 1557-1569.
159. Hiatt WH, Schallhorn RG. Intraoral transplants of cancellous bone and marrow in periodontal lesions. J Periodontol 1973: 44: 194-208.
160. Higashi MK, Veenstra DL, del Aguila M, Hujoel P. The cost-effectiveness of interleukin-1 genetic testing for periodontal disease. J Periodontol 2002: 73: 1474-1484.
161. Hinrichs JE, Wolff LF, Pihlstrom BL, Schaffer EM, Liljemark WF, Bandt CL. Effects of scaling and root planing on subgingival microbial proportions standardized in terms of their naturally occurring distribution. J Periodontol 1985: 56: 187-194.
162. Hirschfeld L, Wasserman B. A long-term survey of tooth loss in 600 treated periodontal patients. J Periodontol 1978: 49: 225-237.
163. Holm G. Smoking as an additional risk for tooth loss. J Periodontol 1994: 65: 996-1001.
164. Holman WL. Focal infection and 'elective localization'. Arch Pathol Lab Med 1928: 5: 68-136.
165. Holt SC, Kesavalu L, Walker S, Genco CA. Virulence factors of Porphyromonas gingivalis. Periodontol 2000 1999: 20: 168-238.
166. Holt SC, Ebersole JL. Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the 'red complex', a prototype polybacterial pathogenic consortium in periodontitis. Periodontol 2000 2005: 38: 72-122.
167. Hornef MW, Wick MJ, Rhen M, Normark S. Bacterial strategies for overcoming host innate and adaptive immune responses. Nat Immunol 2002: 3: 1033-1040.
168. Hugoson A. Gingival inflammation and female sex hormones. A clinical investigation of pregnant women and experimental studies in dogs. J Periodontal Res 1970: 5(Suppl.): 1-18.
169. Hugoson A, Sjödin B, Norderyd O. Trends over 30years, 1973-2003, in the prevalence and severity of periodontal disease. J Clin Periodontol 2008: 35: 405-414.
170. Hujoel PP, DeRouen TA. Validity issues in split-mouth trials. J Clin Periodontol 1992: 19: 625-627.
171. Hujoel PP, Drangsholt M, Spiekerman C, DeRouen TA. Periodontal disease and coronary heart disease risk. J Am Med Assoc 2000: 284: 1406-1410.
172. Hujoel PP, Drangsholt M, Spiekerman C, DeRouen TA. Examining the link between coronary heart disease and the elimination of chronic dental infections. J Am Dent Assoc 2001: 132: 883-889.
173. Hujoel PP, White BA, Garcia RI, Listgarten MA. The dentogingival epithelial surface area revisited. J Periodontal Res 2001: 36: 48-55.
174. Hujoel PP. Does chronic periodontitis cause coronary heart disease? A review of the literature. J Am Dent Assoc 2002: 133: 31S-36S.
175. Hujoel PP, Cunha-Cruz J, Selipsky H, Saver BG. Abnormal pocket depth and gingival recession as distinct phenotypes. Periodontol 2000 2005: 39: 22-29.
176. Hunter J. In: A Practical Treatise on the Diseases of the Teeth; intended as a supplement to the Natural History of Those Parts. Chapter III. Of the Diseases of the Gums, and the Consequences of them. London: J. Johnson, 1778, 55-58.
177. Inagaki S, Onishi S, Kuramitsu H, Sharma A. Porphyromonas gingivalis vesicles enhance attachment, and the leucine-rich repeat BspA protein is required for the invasion of epithelial cells by 'Tannerella forsythia'. Infect Immun 2006: 74: 5023-5028.
178. Janket SJ, Wightman A, Baird AE, Van Dyke TE, Jones JA. Does periodontal treatment improve glycemic control in diabetic patients? A meta-analysis of intervention studies. J Dent Res 2005: 84: 1154-1159.
179. Jeffcoat MK, Bray KS, Ciancio SG, Dentino AR, Fine DH, Gordon JM, Gunsolley JC, Killoy WJ, Lowenguth RA, Magnusson NI, Offenbacher S, Palcanis KG, Proskin HM, Finkelman RD, Flashner M. Adjunctive use of a subgingival controlled-release chlorhexidine chip reduces probing depth and improves attachment level compared with scaling and root planing alone. J Periodontol 1998: 69: 989-997.
180. Jenkins DJ, Axelsen M, Kendall CW, Augustin LS, Vulksan V, Smith U. Dietary fibre, lente carbohydrates and the insulin-resistant diseases. Br J Nutr 2000: 83(Suppl.): 157-163.
181. Jepsen S, Eberhard J, Fricke D, Hedderich J, Siebert R, Açil Y. Interleukin-1 gene polymorphisms and experimental gingivitis. J Clin Periodontol 2003: 30: 102-106.
182. Jin L, Wong KY, Leung WK, Corbet EF. Comparison of treatment response patterns following scaling and root planing in smokers and non-smokers with untreated adult periodontitis. J Clin Dent 2000: 11: 35-41.
183. Johnson RH. Principles in periodontal osseous resection. Dent Clin North Am 1976: 20: 35-59.
184. Jori G, Fabris C, Soncin M, Ferro S, Coppellotti O, Dei D, Fantetti L, Chiti G, Roncucci G. Photodynamic therapy in the treatment of microbial infections: basic principles and perspective applications. Lasers Surg Med 2006: 38: 468-481.
185. Joss A, Adler R, Lang NP. Bleeding on probing. A parameter for monitoring periodontal conditions in clinical practice. J Clin Periodontol 1994: 21: 402-408.
186. Kaldahl WB, Kalkwarf KL, Patil KD, Molvar MP. Responses of four tooth and site groupings to periodontal therapy. J Periodontol 1990: 61: 173-179.
187. Kaldahl WB, Kalkwarf KL, Patil KD, Molvar MP, Dyer JK. Long-term evaluation of periodontal therapy. I. Response to 4 therapeutic modalities. J Periodontol 1996: 67: 93-102.
188. Kaldahl WB, Kalkwarf KL, Patil KD, Molvar MP, Dyer JK. Long-term evaluation of periodontal therapy: II. Incidence of sites breaking down. J Periodontol 1996: 67: 103-108.
189. Kanzler H, Barrat FJ, Hessel EM, Coffman RL. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med 2007: 13: 552-559.
190. Kao RT, Conte G, Nishimine D, Dault S. Tissue engineering for periodontal regeneration. J Calif Dent Assoc 2005: 33: 205-213.
191. Karpinia KA, Matt M, Fennell RS 3rd, Hefti AF. Factors affecting cyclosporine-induced gingival overgrowth in pediatric renal transplant recipients. Pediatr Dent 1996: 18: 450-455.
192. Kato S, Nakashima K, Inuoe M, Tomioka J, Nonaka K, Nishihar T, Kowashi Y. Human epithelial cell death caused by Actinobacillus actinomycetemcomitans infection. J Med Microbiol 2000: 49: 739-745.
193. Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux NY, Goncalves RB, Valverde P, Dibart S, Li YP, Miranda LA, Ernst CW, Izumi Y, Taubman MA. B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease. Am J Pathol 2006: 169: 987-998.
194. Kenney EB, Lekovic V, Han T, Carranza FA Jr, Dimitrijevic B. The use of a porous hydroxylapatite implant in periodontal defects. I. Clinical results after six months. J Periodontol 1985: 56: 82-88.
195. Kenney EB, Lekovic V, Sa Ferreira JC, Han T, Dimitrijevic B, Carranza FA Jr. Bone formation within porous hydroxylapatite implants in human periodontal defects. J Periodontol 1986: 57: 76-83.
196. Kenney EB, Lekovic V, Carranza FA Jr, Dimitrijevic B, Han T, Takei H. A comparative clinical study of solid and granular porous hydroxylapatite implants in human periodontal osseous defects. J Biomed Mater Res 1988: 22: 1233-1243.
197. Kiger RD, Nylund K, Feller RP. A comparison of proximal plaque removal using floss and interdental brushes. J Clin Periodontol 1991: 18: 681-684.
198. Kigure T, Saito A, Seida K, Yamada S, Ishihara K, Okuda K. Distribution of Porphyromonas gingivalis and Treponema denticola in human subgingival plaque at different periodontal depths examined by immunohistochemical methods. J Periodontal Res 1995: 30: 332-341.
199. Kilian M, Frandsen EV, Haubek D, Poulsen K. The etiology of periodontal disease revisited by population genetic analysis. Periodontol 2000 2006: 42: 158-179.
200. Kim J, Amar S. Periodontal disease and systemic conditions: a bidirectional relationship. Odontology 2006: 94: 10-21.
201. Kinane DF, Shiba H, Hart TC. The genetic basis of periodontitis. Periodontol 2000 2005: 39: 91-117.
202. Kirkwood KL, Cirelli JA, Rogers JE, Giannobile WV. Novel host response therapeutic approaches to treat periodontal diseases. Periodontol 2000 2007: 43: 294-315.
203. Kirkwood KL, Li F, Rogers JE, Otremba J, Coatney DD, Kreider JM, D'Silva NJ, Chakravarty S, Dugar S, Higgins LS, Protter AA, Medicherla S. A p38α selective mitogen-activated protein kinase inhibitor prevents periodontal bone loss. J Pharmacol Exp Ther 2007: 320: 56-63.
204. Kitano H, Oda K. Robustness trade-offs and host-microbial symbiosis in the immune system. Mol Syst Biol 2006: 3: 1-10.
205. Knöfler GU, Purschwitz RE, Jentsch HF. Clinical evaluation of partial- and full-mouth scaling in the treatment of chronic periodontitis. J Periodontol 2007: 78: 2135-2142.
206. Kolenbrander PE, Andersen RN, Kazmerzak K, Wu R, Palmer RJ. Spatial organization of oral bacteria in biofilms. Methods Enzymol 1999: 310: 322-332.
207. Kolenbrander PE, Palmer RJ Jr, Rickard AH, Jakubovics NS, Chalmers NI, Diaz PI. Bacterial interactions and successions during plaque development. Periodontol 2000 2006: 42: 47-79.
208. Kornman KS, Crane A, Wang HY, di Giovine FS, Newman MG, Pirk FW, Wilson TG Jr, Higginbottom FL, Duff GW. The interleukin-1 genotype as a severity factor in adult periodontal disease. J Clin Periodontol 1997: 24: 72-77.
209. Kornman KS. Mapping the pathogenesis of periodontitis: a new look. J Periodontol 2008: 79: 1560-1568.
210. Kressin NR, Boehmer U, Nunn ME, Spiro A 3rd. Increased preventive practices lead to greater tooth retention. J Dent Res 2003: 82: 223-227.
211. Krisanaprakornkrit S, Weinberg A, Perez CN, Dale BA. Expression of the peptide antibiotic human β-defensin 1 in cultured gingival epithelial cells and gingival tissue. Infect Immun 1998: 66: 4222-4228.
212. Kroes I, Lepp PW, Relman DA. Bacterial diversity within the human subgingival crevice. Proc Natl Acad Sci USA 1999: 96: 14547-14552.
213. Kumar PS, Leys EJ, Bryk JM, Martinez FJ, Moeschberger ML, Griffen AL. Changes in periodontal health status are associated with bacterial community shifts as assessed by quantitative 16S cloning and sequencing. J Clin Microbiol 2006: 44: 3665-3673.
214. Kuramitsu HK, He X, Lux R, Anderson MH, Shi W. Interspecies interactions within oral microbial communities. Microbiol Mol Biol Rev 2007: 71: 653-670.
215. Kwok V, Caton JG. Commentary: prognosis revisited: a system for assigning periodontal prognosis. J Periodontol 2007: 78: 2063-2071.
216. Laine MA. Effect of pregnancy on periodontal and dental health. Acta Odontol Scand 2002: 60: 257-264.
217. Lalla E. Periodontal infections and diabetes mellitus: when will the puzzle be complete? J Clin Periodontol 2007: 34: 913-916.
218. Lamell CW, Griffen AL, McClellan DL, Leys EJ. Acquisition and colonization stability of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in children. J Clin Microbiol 2000: 38: 1196-1199.
219. Lang NP, Joss A, Orsanic T, Gusberti FA, Siegrist BE. Bleeding on probing. A predictor for the progression of periodontal disease? J Clin Periodontol 1986: 13: 590-596.
220. Lang NP, Adler R, Joss A, Nyman S. Absence of bleeding on probing. An indicator of periodontal stability. J Clin Periodontol 1990: 17: 714-721.
221. Lang NP, Bartold PM, Cullinan M, Jeffcoat M, Mombelli A, Murakami S, Page R, Papapanou P, Tonetti M, Van Dyke T. Consensus report. Aggressive periodontitis. Ann Periodontol 1999: 4: 53.
222. Lang NP, Schätzle MA, Löe H. Gingivitis as a risk factor in periodontal disease. J Clin Periodontol 2009: 36(Suppl.): 3-8.
223. Laskaris G, Potouridou I, Laskaris M, Stratigos J. Gingival lesions of HIV infection in 178 Greek patients. Oral Surg Oral Med Oral Pathol 1992: 74: 168-171.
224. Lebel S, Trinkaus E, Faure M, Fernandez Ph, Guérin C, Richter D, Mercier N, Valladas H, Wagner GA. Comparative morphology and paleobiology of Middle Pleistocene human remains from the Bau de l'Aubésier, Vaucluse, France. Proc Natl Acad Sci USA 2001: 98: 11097-11102.
225. Lesaffre E, Garcia Zattera MJ, Redmond C, Huber H, Needleman I, on behalf of the ISCB subcommittee on dentistry. Reported methodological quality of split-mouth studies. J Clin Periodontol 2007: 34: 756-761.
226. Liese AD, Roach AK, Sparks KC, Marquart L, D'Agostino RB Jr, Mayer-Davis EJ. Whole-grain intake and insulin sensitivity: the insulin resistance atherosclerosis study. Am J Clin Nutr 2003: 78: 965-971.
227. Linden G, Patterson C, Evans A, Kee F. Obesity and periodontitis in 60-70-year-old men. J Clin Periodontol 2007: 34: 461-466.
228. Lindhe J, Westfelt E, Nyman S, Socransky SS, Heijl L, Bratthall G. Healing following surgical/non-surgical treatment of periodontal disease. A clinical study. J Clin Periodontol 1982: 9: 115-128.
229. Listgarten MA. Structure of the microbial flora associated with periodontal health and disease in man. A light and electron microscopic study. J Periodontol 1976: 47: 1-18.
230. Liu D, Xu JK, Figliomeni L, Huang L, Pavlos NJ, Rogers M, Tan A, Price P, Zheng MH. Expression of RANKL and OPG mRNA in periodontal disease: possible involvement in bone destruction. Int J Mol Med 2003: 11: 17-21.
231. Löe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963: 21: 533-551.
232. Löe H, Theilade E, Jensen SB. Experimental gingivitis in man. J Periodontol 1965: 36: 177-187.
233. Löe H, Theilade E, Jensen SB, Schiøtt CR. Experimental gingivitis in man. 3. Influence of antibiotics on gingival plaque development. J Periodontal Res 1967: 2: 282-289.
234. Löe H, Anerud A, Boysen H, Morrison E. Natural history of periodontal disease in man. Rapid, moderate and no loss of attachment in Sri Lankan laborers 14 to 46years of age. J Clin Periodontol 1986: 13: 431-445.
235. Löe H, Brown LJ. Early onset periodontitis in the United States of America. J Periodontol 1991: 62: 608-616.
236. Loesche WJ, Schork A, Terpenning MS, Chen YM, Kerr C, Dominguez BL. The relationship between dental disease and cerebral vascular accident in elderly United States veterans. Ann Periodontol 1998: 3: 161-174.
237. Loomer PM. Microbiological diagnostic testing in the treatment of periodontal diseases. Periodontol 2000 2004: 34: 49-56.
238. Loos B, Claffey N, Crigger M. Effects of oral hygiene measures on clinical and microbiological parameters of periodontal disease. J Clin Periodontol 1988: 15: 211-216.
239. Loscalzo J, Kohane I, Barabasi AL. Human disease classification in the postgenomic era: a complex systems approach to human pathobiology. Mol Syst Biol 2007: 4: 1-11.
240. Luepke PG, Mellonig JT, Brunsvold MA. A clinical evaluation of a bioresorbable barrier with and without decalcified freeze-dried bone allograft in the treatment of molar furcations. J Clin Periodontol 1997: 24: 440-446.
241. Lynch SE, Williams RC, Polson AM, Howell TH, Reddy MS, Zappa UE, Antoniades HN. A combination of platelet-derived and insulin-like growth factors enhance periodontal regeneration. J Clin Periodontol 1989: 16: 545-548.
242. Lynch SE, de Castilla GR, Williams RC, Kiritsy CP, Howell TH, Reddy MS, Antoniades HN. The effects of short-term application of a combination of platelet-derived and insulin-like growth factors on periodontal wound healing. J Periodontol 1991: 62: 458-467.
243. Madianos PN, Bobetsis YA, Kinane DF. Generation of inflammatory stimuli: how bacteria set up inflammatory responses in the gingiva. J Clin Periodontol 2005: 32(Suppl. 6): 57-71.
244. Magnusson I, Batich C, Collins BR. New attachment formation following controlled tissue regeneration using biodegradable membranes. J Periodontol 1988: 59: 1-6.
245. Mah TF, O'Toole GA. Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol 2001: 9: 34-39.
246. Mahanonda R, Pichyangkul S. Toll-like receptors and their role in periodontal health and disease. Periodontol 2000 2007: 43: 41-55.
247. Maier AW, Orban B. Gingivitis in pregnancy. Oral Surg Oral Med Oral Pathol 1949: 2: 334-373.
248. Manson JD, Lehner T. Clinical features of juvenile periodontitis (periodontosis). J Periodontol 1974: 45: 636-640.
249. Marazita ML, Burmeister JA, Gunsolley JC, Koertge TE, Lake K, Schenkein HA. Evidence for autosomal dominant inheritance and race-specific heterogeneity in early-onset periodontitis. J Periodontol 1994: 65: 623-630.
250. Mariotti A. Sex steroid hormones and cell dynamics in the periodontium. Crit Rev Oral Biol Med 1994: 5: 27-53.
251. Mariotti A. Dental plaque-induced gingival diseases. Ann Periodontol 1999: 4: 7-19.
252. Mariotti A. Efficacy of chemical root surface modifiers in the treatment of periodontal disease. A systematic review. Ann Periodontol 2003: 8: 205-226.
253. Marsh PD, Percival RS. The oral microflora - friend or foe? Can we decide? Int Dent J 2006: 56(Suppl. 1): 233-239.
254. Marshall RI. Gingival defensins: linking the innate and adaptive immune responses to dental plaque. Periodontol 2000 2004: 35: 14-20.
255. Martinez-Canut P, Lorca A, Magán R. Smoking and periodontal disease severity. J Clin Periodontol 1995: 22: 743-749.
256. Matia JI, Bissada NF, Maybury JE, Ricchetti P. Efficiency of scaling of the molar furcation area with and without surgical access. Int J Periodontics Restorative Dent 1986: 6: 24-35.
257. Mattila KJ, Nieminen MS, Valtonen VV, Rasi VP, Kesäniemi YA, Syrjälä SL, Jungeli PS, Isoluoma M, Hietaniemi K, Jokinen MJ. Association between dental health and acute myocardial infarction. BMJ 1989: 298: 779-781.
258. Matuliene G, Pjetursson BE, Salvi GE, Schmidlin K, Brägger U, Zwahlen M, Lang NP. Influence of residual pockets on progression of periodontitis and tooth loss: results after 11years of maintenance. J Clin Periodontol 2008: 35: 685-695.
259. Melcher AH. On the repair potential of periodontal tissues. J Periodontol 1976: 47: 256-260.
260. Mellonig JT, Seamons BC, Gray JL, Towle HJ. Clinical evaluation of guided tissue regeneration in the treatment of gradeII molar furcation invasions. Int J Periodontics Restorative Dent 1994: 14: 254-271.
261. Mendez MV, Scott T, LaMorte W, Vokonas P, Menzoian JO, Garcia R. An association between periodontal disease and peripheral vascular disease. Am J Surg 1998: 176: 153-157.
262. Merchant AT, Pitiphat W, Franz M, Joshipura K. Whole-grain and fiber intakes and periodontitis in men. Am J Clin Nutr 2006: 83: 1395-1400.
263. Merritt AH. Progressive dentistry and stomatology: 2. Periodontology, with special reference to periodontoclasia. J Dent Res 1920: 2: 77-87.
264. Merritt AH. A brief history of periodontology. J Dent Res 1921: 3: cxlix-clxi.
265. Meyer DH, Sreenivasan PK, Fives-Taylor PM. Evidence for invasion of a human oral cell line by Actinobacillus actinomycetemcomitans. Infect Immun 1991: 59: 2719-2726.
266. Michalowicz BS, Aeppli D, Virag JG, Klump DG, Hinrichs JE, Segal NL, Bouchard TJ Jr, Pihlstrom BL. Periodontal findings in adult twins. J Periodontol 1991: 62: 293-299.
267. Michalowicz BS, Diehl SR, Gunsolley JC, Sparks BS, Brooks CN, Koertge TE, Califano JV, Burmeister JA, Schenkein HA. Evidence of a substantial genetic basis for risk of adult periodontitis. J Periodontol 2000: 71: 1699-1707.
268. Michalowicz BS, Hodges JS, DiAngelis AJ, Lupo VR, Novak MJ, Ferguson JE, Buchanan W, Bofill J, Papapanou PN, Mitchell DA, Matseoane S, Tschida PA. Treatment of periodontal disease and the risk of preterm birth. N Engl J Med 2006: 355: 1885-1894.
269. Miller PD Jr, Allen EP. The development of periodontal plastic surgery. Periodontol 2000 1996: 11: 7-17.
270. Miller WD. The Micro-organisms of the Human Mouth. Philadelphia, PA: S.S. White Dental Mfg. Co., 1890: 321-334.
271. Miller WD. The human mouth as a focus of infection. Dent Cosmos 1891: 33: 689-713.
272. Mombelli A, Schmid B, Rutar A, Lang NP. Persistence patterns of Porphyromonas gingivalis, Prevotella intermedia/nigrescens, and Actinobacillus actinomycetemcomitans after mechanical therapy of periodontal disease. J Periodontol 2000: 71: 14-21.
273. Mongardini C, van Steenberghe D, Dekeyser C, Quirynen M. One-stage full- versus partial-mouth disinfection in the treatment of chronic adult or generalized early-onset periodontitis. I. Long-term clinical observations. J Periodontol 1999: 70: 632-645.
274. Moore WEC, Moore LVH. The bacteria of periodontal diseases. Periodontol 2000 1994: 5: 66-77.
275. Mucci LA, Björkman L, Douglas CW, Pedersen NL. Environmental and heritable factors in the etiology of oral diseases - a population based study of Swedish twins. J Dent Res 2005: 84: 800-805.
276. Murayama Y, Kurihara H, Nagai A, Dompkowski D, van Dyke TE. Acute necrotizing ulcerative gingivitis risk factors involving host defence mechanisms. Periodontol 2000 1994: 6: 116-124.
277. Murphy K, Gunsolley J. Guided tissue regeneration for the treatment of periodotal intrabony and furcation defects. A systematic review. Ann Periodontol 2003: 8: 266-302.
278. National Center for Health Statistics. NHANES III Reference Manual and Reports. Hyattsville, MD: Centers for Disease Control and Prevention, 1996: URL http://www.cdc.gov/nchs/nhanes/nh3rrm.htm.
279. Needleman IG, Worthington HV, Giedrys-Leeper E, Tucker RJ. Guided tissue regeneration for periodontal infra-bony defects. Cochrane Database Syst Rev 2006: DOI:10.1002/14651858.CD001724.pub2.
280. Needleman I, Suvan J, Gilthorpe MS, Tucker R, St George G, Giannobile W, Tonetti M, Jarvis M. A randomized-controlled trial of low-dose doxycycline for periodontitis in smokers. J Clin Periodontol 2007: 34: 325-333.
281. Nelson KE, Fleischmann RD, DeBoy RT, Paulsen IT, Fouts DE, Eisen JA, Daugherty SC, Dodson RJ, Durkin AS, Gwinn M, Haft DH, Kolonay JF, Nelson WC, Mason T, Tallon L, Gray J, Granger D, Tettelin H, Dong H, Galvin JL, Duncan MJ, Dewhirst FE, Fraser CM. Complete genome sequence of the oral pathogen bacterium Porphyromonas gingivalis strain W83. J Bacteriol 2003: 185: 5591-5601.
282. Nesse W, Abbas F, van der Ploeg I, Spijkervet FK, Dijkstra PU, Vissink A. Periodontal inflamed surface area: quantifying inflammatory burden. J Clin Periodontol 2008: 35: 668-673.
283. Nicholson JK. Editorial. Global systems biology, personalized medicine and molecular epidemiology. Mol Syst Biol 2006: 210: 1-6.
284. Nishida M, Grossi SG, Dunford RG, Ho AW, Trevisan M, Genco RJ. Dietary vitaminC and the risk for periodontal disease. J Periodontol 2000: 71: 1215-1223.
285. Nørskov-Lauritsen N, Kilian M. Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter aphrophilus to include Vfactor-dependent and V factor-independent isolates. Int J Syst Evol Microbiol 2006: 56: 2135-2146.
286. Novak MJ, Johns LP, Miller RC, Bradshaw MH. Adjunctive benefits of subantimicrobial dose doxycycline in the management of severe, generalized, chronic periodontitis. J Periodontol 2002: 73: 762-769.
287. Nyman S, Lindhe J, Rosling B. Periodontal surgery in plaque-infected dentitions. J Clin Periodontol 1977: 4: 240-249.
288. Ochsenbein C. A primer for osseous surgery. Int J Periodontics Restorative Dent 1986: 6: 9-47.
289. Offenbacher S, Katz V, Fertik G, Collins J, Boyd D, Maynor G, McKaig R, Beck J. Periodontal infection as a possible risk factor for preterm low birth weight. J Periodontol 1996: 67(Suppl.): 1103-1113.
290. Offenbacher S, Beck JD, Lieff S, Slade G. Role of periodontitis in systemic health: spontaneous preterm birth. J Dent Educ 1998: 62: 852-858.
291. Offenbacher S, Barros SP, Singer RE, Moss K, Williams RC, Becker JD. Periodontal disease at the biofilm-gingival interface. J Periodontol 2007: 78: 1911-1925.
292. Offenbacher S, Barros SP, Beck JD. Rethinking periodontal inflammation. J Periodontol 2008: 79: 1577-1584.
293. Offenbacher S, Beck JD, Moss K, Mendoza L, Paquette DW, Barrow DA, Couper DJ, Stewart DD, Falkner KL, Graham SP, Grossi S, Gunsolley JC, Madden T, Maupome G, Trevisan M, Van Dyke TE, Genco RJ. Results from the periodontitis and vascular eveents (PAVE) study: a pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a secondary prevention model of cardiovascular disease. J Periodontol 2009: 80: 190-201.
294. Padbury A Jr, Eber R, Wang HL. Interactions between the gingiva and the margin of restorations. J Clin Periodontol 2003: 30: 379-385.
295. Page RC, Schroeder HE. Pathogenesis of inflammatory periodontal disease. Lab Invest 1976: 33: 235-249.
296. Page RC, Kornman KS. The pathogenesis of human periodontitis: an introduction. Periodontol 2000 1997: 14: 9-11.
297. Page RC. The pathobiology of periodontal diseases may affect systemic diseases: inversion of a paradigm. Ann Periodontol 1998: 3: 108-120.
298. Page RC. Milestones in periodontal research and the remaining critical issues. J Periodontal Res 1999: 34: 331-339.
299. Page RC, Krall EA, Martin J, Mancl L, Garcia RI. Validity and accuracy of a risk calculator in predicting periodontal disease. J Am Dent Assoc 2002: 133: 569-576.
300. Page RC, Sturdivant EC. Noninflammatory destructive periodontal disease (NDPD). Periodontol 2000 2002: 30: 24-39.
301. Page RC, Martin J, Krall EA, Mancl L, Garcia R. Longitudinal validation of a risk calculator for periodontal disease. J Clin Periodontol 2003: 30: 819-827.
302. Palmer RJ Jr, Gordon SM, Cisar JO, Kolenbrander PE. Coaggregation-mediated interactions of streptococci and actinomyces detected in initial human dental plaque. J Bacteriol 2003: 185: 3400-3409.
303. Paquette DW, Brodala N, Nichols TC. Cardiovascular disease, inflammation, and periodontal infection. Periodontol 2000 2007: 44: 113-126.
304. Paster BJ, Boches SK, Galvin JL, Ericson RE, Lau CN, Levanos VA, Sahasrabudhe A, Dewhirst FE. Bacterial diversity in human subgingival plaque. J Bacteriol 2001: 183: 3770-3783.
305. Paster BJ, Olsen I, Aas JA, Dewhirst FE. The breadth of bacterial diversity in the human periodontal pocket and other oral sites. Periodontol 2000 2006: 42: 80-87.
306. Patton LL, Phelan JA, Ramos-Gomez FJ, Nittayananta W, Shiboski CH, Mbuguye TL. Prevalence and classification of HIV-associated oral lesions. Oral Dis 2002: 8(Suppl. 2): 98-109.
307. Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye C. The global burden of oral diseases and risks to oral health. Bull World Health Organ 2005: 83: 661-669.
308. Pihlstrom BL, McHugh RB, Oliphant TH, Ortiz-Campos C. Comparison of surgical and nonsurgical treatment of periodontal disease. A review of current studies and additional results after 61/2 years. J Clin Periodontol 1983: 10: 524-541.
309. Pihlstrom BL, Fine DH. Aggressive periodontitis in adolescents in Morocco. Lancet 2008: 371: 188-189.
310. Pischon N, Heng N, Bernimoulin JP, Kleber BM, Willich SN, Pischon T. Obesity, inflammation, and periodontal disease. J Dent Res 2007: 86: 400-409.
311. Polimeni G, Xiropaidis AV, Wikesjö UME. Biology and principles of periodontal wound healing/regeneration. Periodontol 2000 2006: 41: 30-47.
312. Pontoriero R, Nyman S, Lindhe J, Rosenberg E, Sanavi F. Guided tissue regeneration in the treatment of furcation defects in man. J Clin Periodontol 1987: 14: 618-620.
313. Pontoriero R, Lindhe J, Nyman S, Karring T, Rosenberg E, Sanavi F. Guided tissue regeneration in degreeII furcation involved mandibular molars. J Clin Periodontol 1988: 15: 247-254.
314. Porter SR, Luker J, Scully C, Glover S, Griffiths MJ. Orofacial manifestations of a group of British patients infected with HIV-1. J Oral Pathol Med 1989: 18: 47-48.
315. Preber H, Bergström J. Cigarette smoking in patients referred for periodontal treatment. Scand J Dent Res 1986: 94: 102-108.
316. Preber H, Bergström J. Effect of cigarette smoking on periodontal healing following surgical therapy. J Clin Periodontol 1990: 17: 324-328.
317. Preshaw PM, Hefti AF, Novak MJ, Michalowicz BS, Pihlstrom BL, Schoor R, Trummel CL, Dean J, van Dyke TE, Walker CB, Bradshaw MH. Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: a multicenter trial. J Periodontol 2004: 75: 1068-1076.
318. Preshaw PM, Hefti AF, Bradshaw MH. Adjunctive subantimicrobial dose doxycycline in smokers and non-smokers with chronic periodontitis. J Clin Periodontol 2005: 32: 610-616.
319. Preshaw PM, Novak MJ, Mellonig J, Magnusson I, Polson A, Giannobile WV, Rowland RW, Thomas J, Walker C, Dawson DR, Sharkey D, Bradshaw MH. Modified-release subantimicrobial dose doxycycline enhances scaling and root planing in subjects with periodontal disease. J Periodontol 2008: 79: 440-452.
320. Quirynen M, Bollen CM, Vandekerckhove BN, Dekeyser C, Papaioannou W, Eyssen H. Full- versus partial-mouth disinfection in the treatment of periodontal infections: short-term clinical and microbiological observations. J Dent Res 1995: 74: 1459-1467.
321. Ramfjord SP, Caffesse RG, Morrison EC, Hill RW, Kerry GJ, Appleberry EA, Nissle RR, Stults DL. 4 modalities of periodontal treatment compared over 5years. J Clin Periodontol 1987: 14: 445-452.
322. Rams TE, Listgarten MA, Slots J. Utility of radiographic crestal lamina dura for predicting periodontal disease activity. J Clin Periodontol 1994: 21: 571-576.
323. Ranney RR. Classification of periodontal diseases. Periodontol 2000 1993: 2: 13-25.
324. Reddy J, Africa CW, Parker JR. Darkfield microscopy of subgingival plaque of an urban black population with poor oral hygiene. J Clin Periodontol 1986: 13: 578-582.
325. Reddy MS, Geurs NC, Gunsolley JC. Periodontal host modulation with antiproteinases, anti-inflammatory, and bone-sparing agents. A systematic review. Ann Periodontol 2003: 8: 12-37.
326. Reimann HA, Havens WP. Focal infection and systemic disease: a critical appraisal. J Am Med Assoc 1940: 114: 1-6.
327. Renvert S, Wikström M, Dahlen G, Slots J, Egelberg J. Effect of root debridement on the elimination of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis from periodontal pockets. J Clin Periodontol 1990: 17: 345-350.
328. Reynolds MA, Aichelmann-Reidy ME, Branch-Mays GL, Gunsolley JC. The efficacy of bone replacement grafts in the treatment of periodontal osseous defects. A systematic review. Ann Periodontol 2003: 8: 227-265.
329. Roberts AP, Mullany P. Genetic basis of horizontal gene transfer among oral bacteria. Periodontol 2000 2006: 42: 36-46.
330. Robinson P, Deacon SA, Deery C, Heanue M, Walmsley AD, Worthington HV, Glenny AM, Shaw BC. Manual versus powered toothbrushing for oral health. Cochrane Database Syst Rev 2005: DOI:10.1002/14651858.CD002281.pub2.
331. Rosenow EC. The relation of dental infection to systemic disease. Dent Cosmos 1917: 59: 485-491.
332. Ross IF, Thompson RH Jr. A long-term study of root retention in the treatment of maxillary molar with furcation involvement. J Periodontol 1978: 49: 238-244.
333. Ross SE, Malamed EH, Amsterdam M. The contiguous autogenous transplant - its rationale, indications and technique. Periodontics 1966: 4: 246-255.
334. Röthlisberger B, Kuonen P, Salvi GE, Gerber J, Pjetursson BE, Attström R, Joss A, Lang NP. Periodontal conditions in Swiss army recruits: a comparative study between the years 1985, 1996, and 2006. J Clin Periodontol 2007: 34: 860-866.
335. Sabet M, Lee SW, Nauman RK, Sims T, Um HS. The surface (S-) layer is a virulence factor of Bacteroides forsythus. Microbiology 2003: 149: 3617-3627.
336. Saito T, Shimazaki Y, Sakamoto M. Obesity and periodontitis. N Engl J Med 1998: 339: 482-483.
337. Sanz M, Teughels W, on behalf of Group A of the European Workshop on Periodontology. Innovations in non-surgical periodontal therapy: consensus report of the Sixth European Workshop on Periodontology. J Clin Periodontol 2008: 35(Suppl.): 3-7.
338. Saxén L. Juvenile periodontitis. J Clin Periodontol 1980: 7: 1-19.
339. Saxén L, Nevanlinna HR. Autosomal recessive inheritance of juvenile periodontitis: test of a hypothesis. Clin Genet 1984: 25: 332-335.
340. Scannapieco FA, Stewart EM, Mylotte JM. Colonization of dental plaque by respiratory pathogens in medical intensive care patients. Crit Care Med 1992: 20: 740-745.
341. Scannapieco FA, Mylotte JM. Relationships between periodontal disease and bacterial pneumonia. J Periodontol 1996: 67: 1114-1122.
342. Scannapieco FA. Systemic effects of periodontal diseases. Dent Clin North Am 2005: 49: 533-550.
343. Schallhorn RG, Hiatt WH, Boyce W. Iliac transplants in periodontal therapy. J Periodontol 1970: 41: 556-580.
344. Schallhorn RG, Hiatt WH. Human allografts of iliac cancellous bone and marrow in periodontal osseous defects. II. Clinical observations. J Periodontol 1972: 43: 67-81.
345. Schluger S. Osseous resection - a basic principle in periodontal surgery. Oral Surg Oral Med Oral Pathol 1949: 2: 316-325.
346. Schmidlin PR, Beuchat M, Busslinger A, Lehmann B, Lutz F. Tooth substance loss resulting from mechanical, sonic and ultrasonic root instrumentation assessed by liquid scintillation. J Clin Periodontol 2001: 28: 1058-1066.
347. Schroeder HE. The Periodontium. Handbook of Microscopic Anatomy, volume V/5. Berlin: Springer, 1986.
348. Schroeder HE, Listgarten MA. The gingival tissues: the architecture of periodontal protection. Periodontol 2000 1997: 13: 91-120.
349. Schwarz F, Aoki A, Becker J, Sculean A. Laser application in non-surgical periodontal therapy: a systematic review. J Clin Periodontol 2008: 35(Suppl.): 29-44.
350. Sculean A, Reich E, Chiantella GC, Brecx M. Treatment of intrabony periodontal defects with an enamel matrix protein derivative (Emdogain): a report of 32 cases. Int J Periodontics Restorative Dent 1999: 19: 157-163.
351. Sculean A, Nikolidakis D, Schwarz F. Regeneration of periodontal tissues: combinations of barrier membranes and grafting materials - biological foundation and preclinical evidence: a systematic review. J Clin Periodontol 2008: 35(Suppl.): 106-116.
352. Seinost G, Wimmer G, Skerget M, Thaller E, Brodmann M, Gasser R, Bratschko RO, Pilger E. Periodontal treatment improves endothelial dysfunction in patients with severe periodontitis. Am Heart J 2005: 149: 1050-1054.
353. Sepe WW, Bowers GM, Lawrence JJ, Friedlaender GE, Koch RW. Clinical evaluations of freeze-dried bone allografts in periodontal osseous defects: partII. J Periodontol 1978: 49: 9-14.
354. Serino G, Rosling B, Ramberg P, Socransky SS, Lindhe J. Initial outcome and long-term effect of surgical and non-surgical treatment of advanced periodontal disease. J Clin Periodontol 2001: 28: 910-916.
355. Seymour GJ, Gemmell E. Cytokines in periodontal disease: where to from here? Acta Odontol Scand 2001: 59: 167-173.
356. Seymour GJ, Taylor JJ. Shouts and whispers: an introduction to immunoregulation in periodontal disease. Periodontol 2000 2004: 35: 9-13.
357. Shklar G. Ancient India and China. In: Carranza F, Shklar G, editors. History of Periodontology. Chicago, IL: Quintessence Publishing Co. Inc., 2003: 9-11.
358. Shklar G. The Renaissance. In: Carranza F, Shklar G, editors. History of Periodontology. Chicago, IL: Quintessence Publishing Co. Inc., 2003: 43-48.
359. Sicilia A, Arregui I, Gallego M, Cabezas B, Cuesta S. A systematic review of powered vs manual toothbrushes in periodontal cause-related therapy. J Clin Periodontol 2002: 29 (Suppl. 3): 39-54; discussion 90-91.
360. Silness J, Löe H. Periodontal disease in pregnancy. 3. Response to local treatment. Acta Odontol Scand 1966: 24: 747-759.
361. Simonka M, Skaleric U, Hojs D. Condition of teeth and periodontal tissue in patients who had suffered a heart attack. Zobozdrav Vestn 1988: 43: 81-83 [article in Slovenian].
362. Skudutyte-Rysstad R, Eriksen HM, Hansen BF. Trends in periodontal health among 35-year-olds in Oslo, 1973-2003. J Clin Periodontol 2007: 34: 867-872.
363. Slots J. The predominant cultivable organisms in juvenile periodontitis. Scand J Dent Res 1976: 84: 1-10.
364. Socransky SS, Haffajee AD, Goodson JM, Lindhe J. New concepts of destructive periodontal disease. J Clin Periodontol 1984: 11: 21-32.
365. Socransky SS, Haffajee AD. Evidence of bacterial etiology: a historical perspective. Periodontol 2000 1994: 5: 7-25.
366. Socransky SS, Smith C, Martin L, Paster BJ, Dewhirst FE, Levin AE. 'Checkerboard' DNA-DNA hybridization. BioTechniques 1994: 17: 788-792.
367. Socransky SS, Haffajee AD, Cugini MA, Smith C, Kent RL Jr. Microbial complexes in subgingival plaque. J Clin Periodontol 1998: 25: 134-144.
368. Socransky SS, Haffajee AD. Periodontal microbial ecology. Periodontol 2000 2005: 38: 135-187.
369. Söderholm G, Nobréus N, Attström R, Egelberg J. Teaching plaque control. I. A five-visit versus two-visit program. J Clin Periodontol 1982: 9: 203-213.
370. Söderholm G, Egelberg J. Teaching plaque control. II. 30-minute versus 15-minute appointments in a three-visit program. J Clin Periodontol 1982: 9: 214-222.
371. Stahl SS, Froum S. Histologic evaluation of human intraosseous healing responses to the placement of tricalcium phosphate ceramic implants. I. Three to eight months in human intrabony defects. J Periodontol 1986: 57: 211-217.
372. Stahl SS, Froum S, Tarnow D. Human histologic responses to guided tissue regeneration techniques in intrabony lesions. J Clin Periodontol 1990: 17: 191-198.
373. Stahl SS, Froum S. Histologic healing responses in human vertical lesions following the use of osseous allografts and barrier membranes. J Clin Periodontol 1991: 18: 149-152.
374. Stambaugh RV, Dragoo M, Smith DM, Carasali L. The limits of subgingival scaling. Int J Periodontics Restorative Dent 1981: 1: 30-41.
375. Stamm JW. Epidemiology of gingivitis. J Clin Periodontol 1986: 13: 360-366.
376. Stavropoulos A, Mardas N, Herrero F, Karring T. Smoking affects the outcome of guided tissue regeneration with bioresorbable membranes: a retrospective analysis of intrabony defects. J Clin Periodontol 2004: 31: 945-950.
377. Stefanac SJ, Nesbitt SP. Treatment Planning in Dentistry, 2nd edition. St Louis: Mosby, 2007.
378. Summers CJ, Oberman A. Association of oral disease with 12 selected variables: I. periodontal disease. J Dent Res 1968: 47: 457-462.
379. Suntharalingam P, Cvitkovitch DG. Quorum sensing in streptococcal biofilm formation. Trends Microbiol 2005: 13: 3-6.
380. Suzuki A, Ji G, Numabe Y, Muramatsu M, Gomi K, Kanazashi M, Ogata Y, Shimizu E, Shibukawa Y, Ito A, Ito T, Sugaya A, Arai T, Yamada S, Deguchi S, Kamoi K. Single nucleotide polymorphisms associated with aggressive periodontitis and severe chronic periodontitis in Japanese. Biochem Biophys Res Commun 2004: 317: 887-892.
381. Syriänen J, Peltola J, Valtonen V, Iivanainen M, Kaste M, Huttunen JK. Dental infections in association with cerebral infarction in young and middle-aged men. J Intern Med 1989: 225: 179-184.
382. Taichman LS, Eklund StA. Oral contraceptives and periodontal diseases: rethinking the association based upon analysis of National Health and Nutrition Examination Survey data. J Periodontol 2005: 76: 1374-1385.
383. Takeuchi-Hatanaka K, Ohyama H, Nishimura F, Kato-Kogoe N, Soga Y, Matsushita S, Nakasho K, Yamanegi K, Yamada N, Terada N, Takashiba S. Polymorphisms in the 5′ flanking region of IL12RB2 are associated with susceptibility to periodontal diseases in the Japanese population. J Clin Periodontol 2008: 35: 317-323.
384. Tanner A, Maiden MF, Macuch PJ, Murray LL, Kent RL Jr. Microbiota of health, gingivitis, and initial periodontitis. J Clin Periodontol 1998: 25: 85-98.
385. Tanner AC, Milgrom PM, Kent R Jr, Mokeem SA, Page RC, Riedy CA, Weinstein P, Bruss J. The microbiota of young children from tooth and tongue samples. J Dent Res 2002: 81: 53-57.
386. Tanner ACR, Izard J. Tannerella forsythia, a periodontal pathogen entering the genomic era. Periodontol 2000 2006: 42: 88-113.
387. Taubman MA, Valverde P, Han X, Kawai T. Immune response: the key to bone resorption in periodontal disease. J Periodontol 2005: 76: 2033-2041.
388. Taylor GW, Burt BA, Becker MP, Genco RJ, Shlossman M. Glycemic control and alveolar bone loss progression in type2 diabetes. Ann Periodontol 1998: 3: 30-39.
389. Tervonen T, Karjalainen K. Periodontal disease related to diabetic status. A pilot study of the response to periodontal therapy in type1 diabetes. J Clin Periodontol 1997: 24: 505-510.
390. Theilade E, Wright WH, Jensen SB, Löe H. Experimental gingivitis in man. II. A longitudinal clinical and bacteriological investigation. J Periodontal Res 1966: 1: 1-13.
391. Thomas J, Walker C, Bradshaw M. Long-term use of subantimicrobial dose doxycycline does not lead to changes in antimicrobial susceptibility. J Periodontol 2000: 71: 1472-1483.
392. Timmerman MF, van der Weijden GA, van Steenbergen TJ, Mantel MS, de Graaff J, van der Velden U. Evaluation of the long-term efficacy and safety of locally-applied minocycline in adult periodontitis patients. J Clin Periodontol 1996: 23: 707-716.
393. Tomasi C, Schander K, Dahlén G, Wennström JL. Short-term clinical and microbiologic effects of pocket debridement with an Er:YAG laser during periodontal maintenance. J Periodontol 2006: 77: 111-118.
394. Tonetti MS, Imboden MA, Lang NP. Neutrophil migration into the gingival sulcus is associated with transepithelial gradients of interleukin-8 and ICAM-1. J Periodontol 1998: 69: 1139-1147.
395. Tonetti MS, Cortellini P, Suvan JE, Adriaens P, Baldi C, Dubravec D, Fonzar A, Fourmousis I, Magnani C, Muller-Campanile V, Patroni S, Anz M, Vangsted T, Zaalegui I, Oini-Prato G, Lang NP. Generalizability of the added benefits of guided tissue regeneration in the treatment of deep intrabony defects. Evaluation in a multi-center randomized controlled clinical trial. J Periodontol 1998: 69: 1183-1192.
396. Tonetti MS. Cigarette smoking and periodontal diseases: etiology and management of disease. Ann Periodontol 1998: 3: 88-101.
397. Tonetti MS, Mombelli A. Early-onset periodontitis. Ann Periodontol 1999: 4: 39-53.
398. Tonetti MS, Claffey N, on behalf of the European workshop in periodontology group C. Advances in the progress of periodontitis and proposal of definitions of periodontitis case and disaese progression for use in risk factor research. Group C Consensus report of the 5th European Workshop in Periodontology. J Clin Periodontol 2005: 32(Suppl. 6): 210-213.
399. Tonetti MS, D'Aiuto F, Nibali L, Donald A, Storry C, Parkar M, Suvan J, Hingorani AD, Vallance P, Deanfield J. Treatment of periodontitis and endothelial function. N Engl J Med 2007: 356: 911-920.
400. Trombelli L, Farina R. Clinical outcomes with bioactive agents alone or in combination with grafting or guided tissue regeneration. J Clin Periodontol 2008: 35(Suppl.): 117-135.
401. Tuite-McDonnell M, Griffen AL, Moeschberger ML, Dalton RE, Fuerst PA, Leys EJ. Concordance of Porphyromonas gingivalis colonization in families. J Clin Microbiol 1997: 35: 455-461.
402. Tunkel J, Heinecke A, Flemmig TF. A systematic review of efficacy of machine-driven and manual subgingival debridement in the treatment of chronic periodontitis. J Clin Periodontol 2002: 29(Suppl. 3): 72-81.
403. van der Velden U, Varoufaki A, Hutter JW, Xu L, Timmerman MF, van Winkelhoff AJ, Loos BG. Effect of smoking and periodontal treatment on the subgingival microflora. J Clin Periodontol 2003: 30: 603-610.
404. van der Velden U. Purpose and problems of periodontal disease classification. Periodontol 2000 2005: 39: 13-21.
405. Van der Weijden GA, Hioe KP. A systematic review of the effectiveness of self-performed mechanical plaque removal in adults with gingivitis using a manual toothbrush. J Clin Periodontol 2005: 32(Suppl.): 214-228.
406. van Dyke TE, Horoszewicz HU, Cianciola LJ, Genco RJ. Neutrophil chemotaxis dysfunction in human periodontitis. Infect Immun 1980: 27: 124-132.
407. van Dyke TE. Control of inflammation and periodontitis. Periodontol 2000 2007: 45: 158-166.
408. van Dyke TE. The management of inflammation in periodontal disease. J Periodontol 2008: 79(Suppl.): 1601-1608.
409. Waerhaug J. The interdental brush and its place in operative and crown and bridge dentistry. J Oral Rehabil 1976: 3: 107-113.
410. Waite IM. The present status of the gingivectomy procedure. J Clin Periodontol 1975: 2: 241-249.
411. Walker CB. The acquisition of antibiotic resistance in the periodontal microflora. Periodontol 2000 1996: 10: 79-88.
412. Walker C, Thomas J, Nangó S, Lennon J, Wetzel J, Powala C. Long-term treatment with subantimicrobial dose doxycycline exerts no antibacterial effect on the subgingival microflora associated with adult periodontitis. J Periodontol 2000: 71: 1465-1471.
413. Walker C, Preshaw PM, Novak J, Hefti AF, Bradshaw M, Powala C. Long-term treatment with sub-antimicrobial dose doxycycline has no antibacterial effect on intestinal flora. J Clin Periodontol 2005: 32: 1163-1169.
414. Walmsley AD, Lea SC, Landini G, Moses AJ. Advances in power driven pocket/root instrumentation. J Clin Periodontol 2008: 35(Suppl.): 22-28.
415. Wang HL, Greenwell H, Fiorellini J, Giannobile W, Offenbacher S, Salkin L, Townsend C, Sheridan P, Genco RJ, on behalf of the Research, Science and Therapy Committee. Periodontal regeneration. J Periodontol 2005: 76: 1601-1622.
416. Westfelt E, Rylander H, Blohmé G, Jonasson P, Lindhe J. The effect of periodontal therapy in diabetics. Results after 5years. J Clin Periodontol 1996: 23: 92-100.
417. Wiebe CB, Putnins EE. The periodontal disease classification system of the American Academy of Periodontology - an update. J Can Dent Assoc 2000: 66: 594-597.
418. Williams RC, Offenbacher S. Periodontal medicine: the emergence of a new branch of periodontology. Periodontol 2000 2000: 23: 9-12.
419. Williams RC, Paquette DW, Offenbacher S, Adams DF, Armitage GC, Bray K, Caton J, Cochran DL, Drisko CH, Fiorellini JP, Giannobile WV, Grossi S, Guerrero DM, Johnson GK, Lamster IB, Magnusson I, Oringer RJ, Perssson GR, Van Dyke TE, Wolff LF, Santucci EA, Rodda BE, Lessem J. Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial. J Periodontol 2001: 72: 1535-1544.
420. Wilson TG Jr, Glover ME, Malik AK, Schoen JA, Dorsett D. Tooth loss in maintenance patients in a private periodontal practice. J Periodontol 1987: 58: 231-235.
421. Wilson AG. Epigenetic regulation of gene expression in the inflammatory response and relevance to common diseases. J Periodontol 2008: 79: 1514-1519.
422. Wohlfahrt JC, Wu T, Hodges JS, Hinrichs JE, Michalowicz BS. No association between selected candidate gene polymorphisms and severe chronic periodontitis. J Periodontol 2006: 77: 426-436.
423. Yamazaki K, Tabeta K, Nakajima T, Ohsawa Y, Ueki K, Itoh H, Yoshie H. Interleukin-10 gene promoter polymorphism in Japanese patients with adult and early-onset periodontitis. J Clin Periodontol 2001: 28: 828-832.
424. Ylöstalo P, Suominen-Taipale L, Reunanen A, Knuuttila M. Association between body weight and periodontal infection. J Clin Periodontol 2008: 35: 297-304.
425. Yukna RA, Mayer ET, Brite DV. Longitudinal evaluation of durapatite ceramic as an alloplastic implant in periodontal osseous defects after 3years. J Periodontol 1984: 55: 633-637.
426. Yukna RA, Harrison BG, Caudill RF, Evans GH, Mayer ET, Miller S. Evaluation of durapatite ceramic as an alloplastic implant in periodontal osseous defects. II. Twelve month reentry results. J Periodontol 1985: 56: 540-547.
427. Yukna RA, Mayer ET, Amos SM. 5-year evaluation of durapatite ceramic alloplastic implants in periodontal osseous defects. J Periodontol 1989: 60: 544-551.
428. Zambon JJ, Slots J, Genco RJ. Serology of oral Actinobacillus actinomycetemcomitans and serotype distribution in human periodontal disease. Infect Immun 1983: 41: 19-27.
429. Zambon JJ. Actinobacillus actinomycetemcomitans in human periodontal disease. J Clin Periodontol 1985: 12: 1-20.