One stage full-versus partial-mouth disinfection in the treatment of chronic adult or generalized early-onset periodontitis. I. Long-term clinical observations

Journal of Periodontology

Volumn 70, Issue 6, 1999, Pages 632-645

  Mongardini, Claudio ^a   Van Steenberghe, Daniel ^a   Dekeyser, Christel ^a   Quirynen, Marc ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Bacterial infection prevention and control; Chlorhexidine therapeutic use; Dental plaque prevention and control; Periodontitis, early onset therapy; Periodontitis therapy; Planing; Scaling

Indexed keywords

CHLORHEXIDINE;

ADULT; ARTICLE; BACTERIAL INFECTION; CHRONIC DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISINFECTION; DOSE RESPONSE; FEMALE; GINGIVITIS; HUMAN; MALE; MOUTH HYGIENE; ORAL DRUG ADMINISTRATION; PERIODONTITIS; RANDOMIZED CONTROLLED TRIAL; TOOTH PLAQUE; TREATMENT OUTCOME;

ADULT; AEROSOLS; AGED; ANALYSIS OF VARIANCE; ANTI-INFECTIVE AGENTS, LOCAL; CHLORHEXIDINE; DENTAL PLAQUE INDEX; DENTAL PROPHYLAXIS; DENTAL SCALING; EPISODE OF CARE; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MOUTHWASHES; PATIENT SATISFACTION; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL INDEX; PERIODONTITIS; PERIODONTITIS, JUVENILE; REGRESSION ANALYSIS; ROOT PLANING; SINGLE-BLIND METHOD; SMOKING; STATISTICS, NONPARAMETRIC; TIME FACTORS; TREATMENT OUTCOME;

EID: 0032982171     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.1999.70.6.632     Document Type: Article

References (85)

1. Hugoson A, Jordan T. Frequency distribution of individuals aged 20-70 years according to severity of periodontal disease. Community Dent Oral Epidemiol 1982;10:187-192.
2. Brown LJ, Löe H. Prevalence, extent, severity and progression of periodontal disease. Periodontol 2000 1993;2:57-71.
3. Slots J, Rams TE. New views on periodontal microbiota in special patient categories. J Clin Periodontol 1991;18:411-420.
4. Socransky SS, Haffajee AD. The bacterial etiology of destructive periodontal disease: Current concepts. J Periodontol 1992;63:322-331.
5. Wolff L, Dahlèn G, Aeppli D. Bacteria as risk markers for periodontitis. J Periodontol 1994;65(Suppl.):498-510.
6. Kornman KS, Crane A, Wang H-Y, et al. The interleukin-1 genotype as a severity factor in adult periodontal disease. J Clin Periodontol 1997;24:72-77.
7. Genco RJ, Löe H. The role of systemic conditions and disorders in periodontal disease. Periodontol 2000 1993;2:98-116.
8. Michalowicz BS. Genetic and heritable risk factors in periodontal disease. J Periodontol 1994;65:479-488.
9. Slots J, Rosling BG. Suppression of the periodontopathic microflora in localized juvenile periodontitis by systemic tetracycline. J Clin Periodontol 1983;10:465-486.
10. Christersson LA, Slots J, Rosling BG, Genco RJ. Microbiological and clinical effects of surgical treatment of localized juvenile periodontitis. J Clin Periodontol 1985;12:465-476.
11. Pavicic MJAMP, van Winkelhoff AJ, Douqué NH, Steures RWR, de Graaff J. Microbiological and clinical effects of metronidazole and amoxicillin in Actinobacillus actinomycetemcomitans-associated periodontitis. A 2-year evaluation. J Clin Periodontol 1994;21:107-112.
12. Grossi SG, Zambon JJ, Ho AW, et al. Assessment of risk for periodontal disease. I. Risk indicators for attachment loss. J Periodontol 1994;65:260-267.
13. Grossi SG, Genco RJ, Machtei EE, et al. Assessment of risk for periodontal disease. II. Risk indicators for alveolar bone loss. J Periodontol 1995;66:23-29.
14. Grossi SG, Skrepcinski FB, DeCaro T, Zambon JJ, Cummins D, Genco RJ. Response to periodontal therapy in diabetics and smokers. J Periodontol 1996;67 (Suppl.):1094-1102.
15. Haffajee AD, Cugini MA, Dibart S, Smith C, Kent RL Jr., Socransky SS. The effect of SRP on the clinical and microbiological parameters of periodontal diseases. J Clin Periodontol 1997;24:324-334.
16. Mousquës T, Listgarten MA, Philpis RW. Effect of scaling and root planing on the composition of the human subgingival microbial flora. J Periodont Res 1980; 15:144-151.
17. Hinrichs JE, Wolff LF, Pihlström BL, Schaffer EM, Liljemark WF, Bandt CL. Effects of scaling and root planing on subgingival microbial proportions standardized in terms of their naturally occurring distribution. J Periodontol 1985;56:187-194.
18. Van der Velden U, van Winkelhoff AJ, Abbas F, de Graaff J. The habitat of periodontopathic micro-organisms. J Clin Periodontol 1986;13:243-248.
19. van Winkelhoff AJ, Van der Velden U, Clement M, de Graaff J. Intra-oral distribution of black-pigmented Bacteroides species in periodontitis patients. Oral Microbiol Immunol 1988;3:83-85.
20. Asikainen S, Alaluusua S, Saxén L. Recovery of Actinobacillus actinomycetemcomitans from teeth, tongue, and saliva. J Periodontol 1991;62:203-206.
21. Müller HP, Lange DE, Müller RF. Actinobacillus actinomycetemcomitans recovery from extracrevicular locations of the mouth. Oral Microbiol Immunol 1993;8: 344-348.
22. Danser MM, van Winkelhoff AJ, de Graaff J, Loos BG, Van der Velden U. Short-term effect of full-mouth extraction on periodontal pathogens colonizing the oral mucous membranes. J Clin Periodontol 1994;21:484-489.
23. Apse P, Ellen RP, Overall CM, Zarb GA. Microbiota and crevicular fluid collagenase activity in the osseo-integrated dental implant sulcus: A comparison of sites in edentulous and partial edentulous patients. J Periodont Res 1989;24:96-105.
24. Quirynen M, Listgarten MA. The distribution of bacterial morphotypes around natural teeth and titanium implants ad modum Brånemark. Clin Oral Impl Res 1990;1:8-12.
25. Quirynen M, Papaioannou W, van Steenberghe D. Intraoral transmission and the colonization of oral hard surfaces. J Periodontol 1996;67:986-993.
26. Quirynen M, Bollen CML, Vandekerckhove BNA, Dekeyser C, Papaioannou W, Eyssen H. Full-versus partial-mouth disinfection in the treatment of periodontal infections: short-term clinical and microbiological observations. J Dent Res 1995;74:1459-1467.
27. Vandekerckhove BNA, Bollen CML, Dekeyser C, Darius P, Quirynen M. Full-versus partial-mouth disinfection in the treatment of periodontal infections. Long-term clinical observations. J Periodontol 1996;67:1251-1259.
28. Quirynen M, Mongardini C, Pauwels M, Bollen CML, Van Eldere J, van Steenberghe D. One stage full-versus partial-mouth disinfection in the treatment of chronic adult or generalized early-onset periodontitis. II. Long-term impact on microbial load. J Periodontol 1999;70:646-656.
29. Kinane DF, Radvar M. The effect of smoking on mechanical and antimicrobial periodontal therapy. J Periodontol 1997;68:467-472.
30. Mühlemann HR, Son S. Gingival sulcus bleeding - a leading symptom in initial gingivitis. Helv Odontol Acta 1971;15:107-113.
31. Quigley GA, Hein JW. Comparative cleansing efficiency of manual and power brushing. J Am Dent Assoc 1962;65:26-29.
32. Preber H, Linder L, Bergström J. Periodontal healing and periopathogenic microflora in smokers and non-smokers. J Clin Periodontol 1995;22:946-952.
33. Fleiss JL. The Design and Analysis of Clinical Experiments. New York: John Wiley & Sons Inc.; 1996.
34. Papaioannou W, Quirynen M, van Steenberghe D. The influence of periodontitis on the subgingival flora around implants in partially edentulous patients. Clin Oral Impl Res 1996;7:405-409.
35. van Winkelhoff AJ, Van der Velden U, Winkel EG, de Graaff J. Black-pigmented Bacteroides and motile organisms on oral mucosal surfaces in individuals with and without periodontal breakdown. J Periodont Res 1986;21:434-439.
36. Petit MDA, Van Steenbergen TJM, Timmerman MF, de Graaff J, Van der Velden U. Prevalence of periodontitis and suspected periodontal pathogens in families of adult periodontitis patients. J Clin Periodontol 1994;21:76-85.
37. Von Troil-Lindèn B, Torkko H, Alaluusua S, Wolf J, Jousimies-Somer H, Asikainen S. Periodontal findings in spouses: A clinical, radiographic and microbiological study. J Clin Periodontol 1995;22:93-99.
38. Danser MM, Timmerman MF, van Winkelhoff AJ, Van der Velden U. The effect of periodontal treatment on periodontal bacteria on the oral mucous membranes. J Periodontol 1996;67:478-485.
39. Könönen E, Jousimies-Somer H, Asikainen S. Relationship between oral Gram-negative anaerobic bacteria in saliva of the mother and the colonization of her edentulous infant. Oral Microbiol Immunol 1992;7: 273-276.
40. Danser MM. The prevalence of periodontal bacteria colonizing the oral mucous membranes (dissertation). Amsterdam, The Netherlands: Universiteit van Amsterdam; 1996.
41. van Winkelhoff AJ, Van der Velden U, de Graaff J. Microbial succession in recolonizing deep periodontal pockets after a single course of supra- and subgingival debridement. J Clin Periodontol 1988;15:116-122.
42. oller RF. Actinobacillus actinomycetemcomitans contamination of toothbrushes from patients harbouring the organism. J Clin Periodontol 1989;16:388-390.
43. Malmberg E, Birkhed D, Norvenius G, Noren JG, Dahlèn G. Microorganisms on toothbrushes at day-care centers. Acta Odontol Scand 1994;52:93-98.
44. Barnett ML, Baker RL, Olson JW. Material adherent to probes during a periodontal examination. Light and electron microscopic observations. J Periodontol 1982;53:446-448.
45. Papaioannou W, Bollen CML, Van Eldere J, Quirynen M. The adherence of periodontopathogens to periodontal probes. A possible factor in intra-oral transmission? J Periodontol 1996;67:1164-1169.
46. Christersson LA, Slots J, Zambon JJ, Genco RJ. Transmission and colonization of Actinobacillus actinomycetemcomitans in localized juvenile periodontitis patients. J Periodontol 1985;56:127-131.
47. Preus HR, Lassen J, Agss AM, Christersson LA. Prevention of transmission of resistant bacteria between periodontal sites during subgingival application of antibiotics. J Clin Periodontol 1993;20:299-303.
48. Walsh MM, Buchanan SA, Hoover CI, et al. Clinical and microbiologic effects of single-dose metronidazole or scaling and root planing in treatment of adult periodontitis. J Clin Periodontol 1986;13:151-157.
49. Loos B, Claffey N, Egelberg J. Clinical and microbiological effects of root debridement in periodontal furcation pockets. J Clin Periodontol 1988;15:453-463.
50. Bollen CML, Quirynen M. Microbiological response to mechanical treatment in combination with adjunctive therapy. A review of the literature. J Periodontol 1996;67: 1143-1158.
51. Hardy JH, Newman HN, Strahan JD. Direct irrigation and subgingival plaque. J Clin Periodontol 1982;9:57-65.
52. Oosterwaal PJM, Mikx, FHM, Renggli HH. Clearance of a topically applied fluorescein gel from periodontal pockets. J Clin Periodontol 1990;17:613-615.
53. Oosterwaal PJM, Mikx FHM, Van den Brink ME, Renggli HH. Bactericidal concentrations of chlorhexidine-digluconate, amine fluoride gel and stannous fluoride gel for subgingival bacteria tested in serum at short contact times. J Periodont Res 1989;24:155-160.
54. Oosterwaal PJM, Mikx FHM, van 't Hof MA, Renggli HH. Short-term bactericidal activity of chlorhexidine gel, stannous fluoride gel and amine fluoride gel tested in periodontal pockets. J Clin Periodontol 1991;18:97-100.
55. Wolffe GN, Van der Velden U. Reproducibility of phase-contrast microscope measurements of percentage motile microorganisms in samples removed from the dorsum of the tongue. J Periodont Res 1987;22:366-369.
56. Gilmore EL, Bhaskar SN. Effect of tongue brushing on bacteria and plaque formed in vitro. J Periodontol 1972;43:418-422.
57. Schiøtt CR, Briner WW, Loe H. Two years oral use of chlorhexidine in man. II. The effect on the salivary bacterial flora. J Periodont Res 1976;11:145-152.
58. Kalaga A, Addy M, Hunter B. Comparison of chlorhexidine delivery by mouthwash and spray on plaque accumulation. J Periodontol 1989;60:127-130.
59. Magnusson I, Lindhe J, Yoneyama T, Liljenberg B. Recolonisation of a subgingival microbiota following scaling in deep pockets. J Clin Periodontol 1984;11:193-207
60. Segreto VA, Collins EM, Beiswanger BB, et al. A comparison of mouthwashes containing two concentrations of chlorhexidine. J Periodont Res 1986;21(Suppl. 16):23-32.
61. Lindhe J, Westfelt E, Nyman S, Socransky SS, Heijl L, Bratthall G. Healing following surgical/non-surgical treatment of periodontal disease. A clinical study. J Clin Periodontol 1982;9:115-128.
62. Loos B, Nylund K, Claffey N, Egelberg J. Clinical effects of root debridement in molar and non-molar teeth. A 2-year follow up. J Clin Periodontol 1989;16:498-504.
63. Hämmerle CHF, Joss A, Lang NP. Short-term effects of initial periodontal therapy (hygienic phase). J Clin Periodontol 1991;18:233-239.
64. Badersten A, Nilvèus R, Egelberg J. Effect of nonsurgical periodontal therapy. H. Severely advanced periodontitis. J Clin Periodontol 1984;11:63-76.
65. Haffajee AD, Socransky SS, Lindhe J, Kent RL Jr., Okamoto H, Yoneyama T. Clinical risk indicators for periodontal attachment loss. J Clin Periodontol 1991;18:117-125.
66. Grbic JT, Lamster IB, Celenti RS, Fine JB. Risk indicators for future clinical attachment loss in adult periodontitis. Patient variables. J Periodontol 1991;62: 322-329.
67. Pedrazzoli V, Kilian M, Karring T, Kirkegaard E. Effect of surgical and non-surgical periodontal treatment on periodontal status and subgingival microbiota. J Clin Periodontol 1991;18:598-604.
68. Nieminen A, Sirén E, Wolf J, Asikainen S. Prognostic criteria for the efficiency of non-surgical periodontal therapy in advanced periodontitis. J Clin Periodontol 1995;22:153-161.
69. Mombelli A, Lehmann B, Tonetti M, Lang NP. Clinical response to local delivery of tetracycline in relation to overall and local periodontal conditions. J Clin Periodontol 1997;24:470-477.
70. Quinn SM, Zhang J-B, Gunsolley JC, Schenkein JG, Schenkein HA, Tew JG. Influence of smoking and race on immunoglobulin G subclass concentrations in early-onset periodontitis patients. Infect Immun 1996;64:2500-2505.
71. Gunsolley JC, Zambon JJ, Mellott CA, Brooks CN, Kaugars CC. Periodontal therapy in young adults with severe generalized periodontitis. J Periodontol 1994;65:268-273.
72. Sbordone L, Ramaglia L, Gulletta E, lacono, V. Recolonization of the subgingival microflora after scaling and rootplaning in human periodontitis. J Periodontol 1990;61:579-584.
73. Wennström JL, Heijl L, Dahlèn G, Gröndahl K. Periodic subgingival antimicrobial irrigation of periodontal pockets (I). Clinical observations. J Clin Periodontol 1987;14:541-550.
74. Schlagenhauf U, Stellwag P, Fiedler A. Subgingival irrigation in the maintenance phase of periodontal therapy. J Clin Periodontol 1990;17:650-653.
75. Flötra L, Gjermo P, Rölla G, Waerhaug J. A 4-month study on the effect of chlorhexidine mouth washes on 50 soldiers. Scand J Dent Res 1972;80:10-17.
76. Al-Joburi W, Chin Quee T, Lautar C, et al. Effects of adjunctive treatment of periodontitis with tetracycline and spiramycin. J Periodontol 1989;60:533-539.
77. Minabe M, Takeuchi K, Nishimura T, Hori T, Umemoto T. Therapeutic effects of combined treatment using tetracycline-immobilized collagen film and root planing in periodontal furcation pockets. J Clin Periodontol 1991;18:287-290.
78. Newman MG, Kornman KS, Doherty FM. A 6-month multi-center evaluation of adjunctive tetracycline fiber therapy used in conjunction with scaling and root planing in maintenance patients: clinical results. J Periodontol 1994;65:685-691.
79. van Steenberghe D, Bercy P, Kohl J, et al. Subgingival minocycline hydrochloride ointment in moderate to severe chronic adult periodontitis: a randomized, double-blind, vehicle-controlled, multicenter study. J Periodontol 1993;64:637-644.
80. Axelsson P, Kristoffersson K, Karlsson R, Bratthall D. A 30-month longitudinal study of the effects of some oral hygiene measures on Streptococcus mutans and approximal dental caries. J Dent Res 1987;66:761-765.
81. Nowzari H, MacDonald ES, Flynn J, London RM, Morrison JL, Slots J. The dynamics of microbial colonization of barrier membranes for guided tissue regeneration. J Periodontol 1996;67:694-702.
82. Ah MKB, Johnson GK, Kaldahl WB, Patil KD, Kalkwarf KL. The effect of smoking on the response to periodontal therapy. J Clin Periodontol 1994;21:91-97.
83. Peacock ME, Sutherland DE, Schuster GS, et al. The effect of nicotine on reproduction and attachment of human gingival fibroblasts in vitro. J Periodontol 1993;64:658-665.
84. MacFarlane GD, Herzberg MC, Wolff LF, Hardie NA. Refractory periodontitis associated with abnormal polymorphonuclear leukocyte phagocytosis and cigarette smoking. J Periodontol 1992;63:908-913.
85. Johnson JD, Houchens DP, Kluwe WM, Craig DK, Fisher GU. Effects of mainstream and environmental tobacco smoke on the immune system in animals and humans. A review. Crit Rev in Toxicol 1990;20:369-382.