Oral contraceptives and periodontal diseases: Rethinking the association based upon analysis of National Health and Nutrition Examination Survey data

Journal of Periodontology

Volumn 76, Issue 8, 2005, Pages 1374-1385

  Taichman, L Susan ^a,b   Eklund, Stephen A ^b  

^a UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^b UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Contraceptives, oral adverse effects; Gingivitis etiology; National Health and Nutrition Examination survey III; Periodontal diseases epidemiology; Periodontal diseases etiology

Indexed keywords

ORAL CONTRACEPTIVE AGENT;

ADOLESCENT; ADULT; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG MEGADOSE; FEMALE; GINGIVITIS; HEALTH SURVEY; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NATIONAL HEALTH SERVICE; PERIODONTAL DISEASE; PERIODONTITIS; POPULATION DISTRIBUTION; POPULATION RESEARCH; PREMENOPAUSE; PREVALENCE; RISK ASSESSMENT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; UNITED STATES; VALIDATION PROCESS;

ADOLESCENT; ADULT; CONTRACEPTIVES, ORAL, COMBINED; CROSS-SECTIONAL STUDIES; DEMOGRAPHY; FEMALE; HEALTH SURVEYS; HUMANS; LIKELIHOOD FUNCTIONS; LOGISTIC MODELS; MIDDLE AGED; ODDS RATIO; PERIODONTAL DISEASES; PERIODONTAL INDEX; PREVALENCE; UNITED STATES;

EID: 24344497260     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2005.76.8.1374     Document Type: Article

References (56)

1. Hatcher R. Contraceptive Technology, 17th ed. New York: Ardent Media; 1999:405-466.
2. Petitti DB. Epidemiologic assessment of the risks of oral contraception. J Reprod Med 1986;31:887-891.
3. Davis A, Wysocki S. Clinician/patient interaction: Communicating the benefits and risks of oral contraceptives. Contraception 1999;59:39S-42S.
4. Sherif K. Benefits and risks of oral contraceptives. Am J Obstet Gynecol 1999;180:S343-S348.
5. Burkman R, Schlesselman JJ, Zeiman M. Safety concerns and health benefits associated with oral contraception. Am J Obstet Gynecol 2004;190:S5-S22.
6. Mariotti A. Sex steroid hormones and cell dynamics in the periodontium. Crit Rev Oral Biol Med 1994;5: 27-53.
7. Zachariasen RD. The effect of elevated ovarian hormones on periodontal health: Oral contraceptives and pregnancy. Women Health 1993;20:21-30.
8. Sooriyamoorthy M, Gower DB. Hormonal influences on gingival tissue: Relationship to periodontal disease. J Clin Periodontol 1989;16:201-208.
9. Zacharias S, Aguilena H, Assanzo JR, Zantu J. Effects of hormonal and non-hormonal contraceptives on lactation and incidence of pregnancy. Contraception 1984;30:203-206.
10. Amar S, Chung KM. Influence of hormonal variation on the periodontium in women. Periodontol 2000 1994;6: 79-87.
11. Lindhe J, Bjorn AL. Influence of hormonal contraceptives on the gingiva of women. J Periodontal Res 1967;2: 1-6.
12. El-Ashiry GM, el-Kafrawy AH, Nasr MF, Younis N. Effects of oral contraceptives on the gingiva. J Periodontol 1971;42:273-275.
13. Kalkwarf KL. Effect of oral contraceptive therapy on gingival inflammation in humans. J Periodontol 1978;49: 560-563.
14. El-Ashiry GM, el-Kafrawy AH, Nasr MF, Younis N. Comparative study of the influence of pregnancy and oral contraceptives on the gingivae. Oral Surg Oral Med Oral Pathol 1970;30:472-475.
15. Das AK, Bhowmick S, Dutta A. Oral contraceptives and periodontal disease. J Indian Dent Assoc 1971; 43:47-53.
16. Pankhurst CL, Waite IM, Hicks KA, Allenu Y, Harkness RD. The influence of oral contraceptive therapy on the periodontium - duration of drug therapy. J Periodontol 1981;52:617-620.
17. Knight GM, Wade AB. The effects of hormonal contraceptives on the human periodontium. J Periodontal Res 1974;9:18-22.
18. Vittek J, Gordon GG, Rappaport SC, Munnangi PR, Southren AL. Specific progesterone receptors in rabbit gingiva. J Periodontal Res 1982;17:657-661.
19. Lindhe J, Bränemark PI, Lundskog J. Changes in vascular proliferation after local application of sex hormones. J Periodontal Res 1967;2:266-272.
20. Lindhe J, Bränemark PI. Changes in vascular permeability after local application of sex hormones. J Periodontal Res 1967;2:259-265.
21. Lindhe J, Bränemark PI. Changes in microcirculation after local application of sex hormones. J Periodontal Res 1967;2:185-193.
22. Thorogood M. Risk of stroke in users of oral contraceptives. JAMA 1999;281:1255-1256.
23. Schwartz SM, Petitti DB, Siscovick DS, et al. Stroke and use of low-dose oral contraceptives in young women: A pooled analysis of two US studies. Stroke 1998;29: 2277-2284.
24. Connell EB. Oral contraceptives: The current risk-benefit ratio. J Reprod Med 1998;29:513-523.
25. Hannaford PC, Owen-Smith V. Using epidemiological data to guide clinical practice: Review of studies on cardiovascular disease and use of combined oral contraceptives. Br Med J 1998;316:984-987.
26. Klinger G, Eick S, Klinger G, et al. Influence of hormonal contraceptives on microbial flora of the gingival sulcus. Contraception 1998;57:381-384.
27. U.S. Department of Health and Human Services. National Center for Health Statistics. First National Health and Nutrition Examination Survey (NHANES I), 1971-1975. Hyattsville, MD: Centers for Disease Control and Prevention. Available at: http://www.cdc.gov/nchs/nhanes.htm; accessed April 22, 2002.
28. Third National Health and Nutrition Examination Survey, 1988-1994. NHANES III data file (CD-ROM): Hyattsville, MD; Centers for Disease Control and Prevention. 1996; Public use data file documentation number 76200.
29. U.S. Public Health Service. National Center for Health Statistics. Plan and Operation of a Health Examination Survey: United States, 1988-1994. Washington, DC: Government Printing Office; 1994. Number 32.
30. Miller HW. Plan and Operation of the Health and Nutrition Examination Survey, United States, 1971-1973. Vital Health Stat 1, No. 10b. Hyattsville, MD: U.S. Department of Health and Human Services; 1977.
31. Russell AL. A system for scoring prevalence and incidence of periodontal disease. J Dent Res 1956;35: 350-359.
32. Douglass C, Gillings D, Sollecito W, Gammon M. The potential for increase in the periodontal diseases of the aged population. J Periodontol 1983;54:721-730.
33. Borrell LN, Burt BA, Gillespie BW, Lynch J, Neighbors H. Periodontitis in the United States: Beyond black and white. J Public Health Dent 2002;62:92-101.
34. Ezzati T, Massey J, Waksburg J, et al. Sample Design: Third National Health and Nutrition Examination Survey. Hyattsville, MD: National Center for Health Statistics; 1992.
35. Chasan-Taber L, Stampfer MJ. Epidemiology of oral contraceptives and cardiovascular disease Ann Intern Med 1998;128:467-477.
36. Samant A, Malik C, Chabra SK, Devi PK. Gingivitis and periodontal disease in pregnancy. J Periodontal Res 1976;47:415-418.
37. Löe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963;21: 533-551.
38. Hugoson A. Gingivitis in pregnant women. A longitudinal clinical study. Odontol Revy 1971;22:65-84.
39. Raber-Durlacher JE, Leene W, Palmerbouva CCR, Raber J, Abraham-Inpijn L. Experimental gingivitis during pregnancy and post partum: Immuno-histochemical aspects. J Periodontol 1983;64:211-218.
40. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1-6.
41. Beck JD, Löe H. Epidemiological principles in studying periodontal diseases. Periodontol 2000 1993;2: 34-45.
42. Preshaw PM, Knutsen MA, Mariotti A. Experimental gingivitis in women using oral contraceptives. J Dent Res 2001;80:2011-2015.
43. Tilakaratne A, Soory M, Ranasinghe AW, Corea SMX, Ekanayake SL, de Silva M. Effects of hormonal contraceptives on the periodontium, in a population of rural Sri-Lankan women. J Clin Periodontol 2000; 27: 753-757.
44. Hunt RJ. The efficiency of half-mouth examinations in estimating the prevalence of periodontal disease. J Dent Res 1987;66:1044-1048.
45. Albandar JM, Kingman A. Gingival recession, gingival bleeding, and dental calculus in adults 30 years of age and older in the United States, 1988-1994. J Periodontol 1999;70:34-40.
46. Reinhardt RA, Payne JB, Maze CA, Patil KD, Gallagher SJ, Mattson JS. Influence of estrogen and osteopenia/osteoporosis on clinical periodontitis in postmenopausal women. J Periodontol 1999;70:823-828.
47. Norderyd OM, Grossi SG, Machtei EE, et al. Periodontal status of women taking postmenopausal estrogen supplementation. J Periodontol 1993;64:957-962.
48. Barrett-Connor E. Hormone replacement therapy. Br Med J 1998;317:457-461.
49. Krall EA, Dawson-Hughes B, Hannan MT, Wilson WPF, Kiel DP. Post-menopausal estrogen replacement and tooth retention. JAMA 1997;102:536-542.
50. Wilkins K, Johansen H, Beaudet MP, Neutel CI. Oral contraceptive use. Health Rep 2000;11:25-37.
51. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled clinical trial. JAMA 2002;288:321-333.
52. Barrett-Connor E, Grady D. Hormone replacement therapy, heart disease, and other considerations. Annu Rev Public Health 1998;19:55-72.
53. Henderson BE, Paganini-Hill A, Ross RK. Decreased mortality in users of estrogen replacement therapy. Arch Intern Med 1991;151:75-78.
54. Grodstein F, Stampfer MJ, Colditz GA, et al. Postmenopausal hormone therapy and mortality. N Engl J Med 1997;336:1769-1775.
55. Humphrey LL, Chan B, Sox HC. Postmenopausal hormone replacement therapy and the primary prevention of cardiovascular disease. Ann Intern Med 2002;137: 273-284.
56. Grodstein F, Clarkson TB, Manson JE. Understanding the divergent data on postmenopausal hormone therapy. N Engl J Med 2003;348:645-650.