Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L)

Journal of Neuroscience

Volumn 25, Issue 46, 2005, Pages 10637-10647

  Ramsden, Martin ^a   Kotilinek, Linda ^a   Forster, Colleen ^a   Paulson, Jennifer ^a   McGowan, Eileen ^c   SantaCruz, Karen ^a   Guimaraes, Aaron ^a   Yue, Mei ^c   Lewis, Jada ^c   Carlson, George ^d   Hutton, Michael ^c   Ashe, Karen H ^a,b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c MAYO CLINIC   (United States)

^d MCLAUGHLIN RESEARCH INSTITUTE   (United States)

Author keywords

Alzheimer; FTDP 17; Hippocampus; Neurodegeneration; Tau; Transgenic

Indexed keywords

PROTEIN KINASE (CALCIUM,CALMODULIN) II;

AGING; ALZHEIMER DISEASE; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ATROPHY; CELL LOSS; CONTROLLED STUDY; DEGENERATIVE DISEASE; FRONTOTEMPORAL DEMENTIA; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HISTOPATHOLOGY; LIMBIC SYSTEM; MAZE TEST; MOUSE; NEOCORTEX; NERVE CELL; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TAUOPATHY; TRANSGENIC MOUSE;

AGING; ANIMALS; CELL COUNT; DISEASE MODELS, ANIMAL; HUMANS; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; NERVE DEGENERATION; NEUROFIBRILLARY TANGLES; TAUOPATHIES;

EID: 27944491109     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3279-05.2005     Document Type: Article

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