메뉴 건너뛰기




Volumn , Issue , 2011, Pages 113-129

The epidermal growth factor receptor in normal and neoplastic epithelia

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84865192441     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4419-7203-3_5     Document Type: Chapter
Times cited : (1)

References (121)
  • 1
    • 12344299675 scopus 로고    scopus 로고
    • Growth of intestinal epithelium in organ culture is dependent on EGF signalling
    • Abud HE, Watson N, Heath JK (2005) Growth of intestinal epithelium in organ culture is dependent on EGF signalling. Exp Cell Res 303:252-262
    • (2005) Exp Cell Res , vol.303 , pp. 252-262
    • Abud, H.E.1    Watson, N.2    Heath, J.K.3
  • 2
    • 0037449752 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo
    • Andl CD, Mizushima T, Nakagawa H, Oyama K, Harada H, Chruma K, Herlyn M, Rustgi AK (2003) Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo. J biol Chem 278:1824-1830
    • (2003) J Biol Chem , vol.278 , pp. 1824-1830
    • Andl, C.D.1    Mizushima, T.2    Nakagawa, H.3    Oyama, K.4    Harada, H.5    Chruma, K.6    Herlyn, M.7    Rustgi, A.K.8
  • 6
    • 38449087529 scopus 로고    scopus 로고
    • Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer
    • bhola NE, Grandis JR (2008) Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer. Front biosci 13:1857-1865
    • (2008) Front Biosci , vol.13 , pp. 1857-1865
    • Bhola, N.E.1    Grandis, J.R.2
  • 7
  • 8
    • 30044445761 scopus 로고    scopus 로고
    • Rhob protects human keratinocytes from UVb-induced apoptosis through epidermal growth factor receptor signaling
    • Canguilhem b, Pradines A, Baudouin C, Boby C, Lajoie-Mazenc I, Charveron M, Favre G (2005) Rhob protects human keratinocytes from UVb-induced apoptosis through epidermal growth factor receptor signaling. J bio chem 280:43257-43263
    • (2005) J Bio Chem , vol.280 , pp. 43257-43263
    • Canguilhem, B.1    Pradines, A.2    Baudouin, C.3    Boby, C.4    Lajoie-Mazenc, I.5    Charveron, M.6    Favre, G.7
  • 10
    • 0028089832 scopus 로고
    • Epidermal growth factor receptor-mediated cell motility: Phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement
    • Chen P, Xie H, Sekar MC, Gupta K, Wells A (1994) Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, But mitogen-activated protein kinase activity is not sufficient for induced cell movement. J Cell biol 127:847-857
    • (1994) J Cell Biol , vol.127 , pp. 847-857
    • Chen, P.1    Xie, H.2    Sekar, M.C.3    Gupta, K.4    Wells, A.5
  • 11
    • 0030788405 scopus 로고    scopus 로고
    • Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis
    • Chin YE, Kitagawa M, Kuida K, Flavell RA, Fu XY (1997) Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol Cell biol 17:5328-5337
    • (1997) Mol Cell Biol , vol.17 , pp. 5328-5337
    • Chin, Y.E.1    Kitagawa, M.2    Kuida, K.3    Flavell, R.A.4    Fu, X.Y.5
  • 12
    • 40849147041 scopus 로고    scopus 로고
    • EGFR antagonists in cancer treatment
    • Ciardiello F, Tortora G (2008) EGFR antagonists in cancer treatment. N Engl J Med 358:1160-1174
    • (2008) N Engl J Med , vol.358 , pp. 1160-1174
    • Ciardiello, F.1    Tortora, G.2
  • 13
    • 33745828702 scopus 로고    scopus 로고
    • EGF-ERbb signalling: Towards the systems level
    • Citri A, Yarden Y (2006) EGF-ERbb signalling: towards the systems level. Nat Rev Mol Cell biol 7:505-516
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 505-516
    • Citri, A.1    Yarden, Y.2
  • 16
    • 49249084044 scopus 로고    scopus 로고
    • RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: Evidence for molecular and functional interactions between RET and EGFR
    • Croyle M, Akeno N, Knauf JA, Fabbro D, Chen X, Baumgartner JE, Lane HA, Fagin JA (2008) RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: evidence for molecular and functional interactions between RET and EGFR. Cancer Res 68:4183-4191
    • (2008) Cancer Res , vol.68 , pp. 4183-4191
    • Croyle, M.1    Akeno, N.2    Knauf, J.A.3    Fabbro, D.4    Chen, X.5    Baumgartner, J.E.6    Lane, H.A.7    Fagin, J.A.8
  • 18
    • 38349137362 scopus 로고    scopus 로고
    • Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration
    • Dise RS, Frey MR, Whitehead RH, Polk Db (2008) Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration. Am J Physiol Gastrointest Liver Physiol 294:G276-G285
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Dise, R.S.1    Frey, M.R.2    Whitehead, R.H.3    Polk, D.B.4
  • 19
    • 0030755457 scopus 로고    scopus 로고
    • Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-rasHa oncogene but does not block in vitro keratinocyte responses to oncogenic ras
    • Dlugosz AA, Hansen L, Cheng C, Alexander N, Denning MF, Threadgill DW, Magnuson T, Coffey RJ Jr, Yuspa SH (1997) Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-rasHa oncogene but does not block in vitro keratinocyte responses to oncogenic ras. Cancer Res 57:3180-3188
    • (1997) Cancer Res , vol.57 , pp. 3180-3188
    • Dlugosz, A.A.1    Hansen, L.2    Cheng, C.3    Alexander, N.4    Denning, M.F.5    Threadgill, D.W.6    Magnuson, T.7    Coffey, Jr.R.J.8    Yuspa, S.H.9
  • 20
    • 34547758527 scopus 로고    scopus 로고
    • EP2 prostanoid receptor promotes SCC growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways
    • Donnini S, Finetti F, Solito R, Terzuoli E, Sacchetti A, Morbidelli L, Patrignani P, Ziche M (2007) EP2 prostanoid receptor promotes SCC growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways. FASEb J 21:2418-2430
    • (2007) FASEb J , vol.21 , pp. 2418-2430
    • Donnini, S.1    Finetti, F.2    Solito, R.3    Terzuoli, E.4    Sacchetti, A.5    Morbidelli, L.6    Patrignani, P.7    Ziche, M.8
  • 21
    • 0033673340 scopus 로고    scopus 로고
    • EGF regulates early embryonic mouse gut development in chemically defined organ culture
    • Duh G, Mouri N, Warburton D, Thomas DW (2000) EGF regulates early embryonic mouse gut development in chemically defined organ culture. Pediatr Res 48:794-802
    • (2000) Pediatr Res , vol.48 , pp. 794-802
    • Duh, G.1    Mouri, N.2    Warburton, D.3    Thomas, D.W.4
  • 23
    • 18144371160 scopus 로고    scopus 로고
    • Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor
    • El Abaseri Tb, Fuhrman J, Trempus C, Shendrik I, Tennant RW, Hansen LA (2005) Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor. Cancer Res 65:3958-3965
    • (2005) Cancer Res , vol.65 , pp. 3958-3965
    • Abaseri Tb, E.1    Fuhrman, J.2    Trempus, C.3    Shendrik, I.4    Tennant, R.W.5    Hansen, L.A.6
  • 24
    • 31544471428 scopus 로고    scopus 로고
    • Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor
    • El Abaseri Tb, Putta S, Hansen LA (2006) Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor. Carcinogenesis 27:225-231
    • (2006) Carcinogenesis , vol.27 , pp. 225-231
    • Abaseri Tb, E.1    Putta, S.2    Hansen, L.A.3
  • 25
    • 9444277283 scopus 로고    scopus 로고
    • How thyroid tumors start and why it matters: Kinase mutants as targets for solid cancer pharmacotherapy
    • Fagin JA (2004) How thyroid tumors start and why it matters: kinase mutants as targets for solid cancer pharmacotherapy. J Endocrinol 183:249-256
    • (2004) J Endocrinol , vol.183 , pp. 249-256
    • Fagin, J.A.1
  • 26
    • 0037429649 scopus 로고    scopus 로고
    • Neuregulins: Functions, forms, and signaling strategies
    • Falls DL (2003) Neuregulins: functions, forms, and signaling strategies. Exp Cell Res 284:14-30
    • (2003) Exp Cell Res , vol.284 , pp. 14-30
    • Falls, D.L.1
  • 28
    • 52549084857 scopus 로고    scopus 로고
    • Regeneration of human epidermis on acellular dermis is impeded by small-molecule inhibitors of EGF receptor tyrosine kinase
    • Forsberg S, Ostman A, Rollman O (2008) Regeneration of human epidermis on acellular dermis is impeded by small-molecule inhibitors of EGF receptor tyrosine kinase. Arch Dermatol Res 300:505-516
    • (2008) Arch Dermatol Res , vol.300 , pp. 505-516
    • Forsberg, S.1    Ostman, A.2    Rollman, O.3
  • 29
    • 1542374120 scopus 로고    scopus 로고
    • Proteolysis within the membrane: Rhomboids revealed
    • Freeman M (2004) Proteolysis within the membrane: rhomboids revealed. Nat Rev Mol Cell biol 5:188-197
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 188-197
    • Freeman, M.1
  • 30
    • 33751085125 scopus 로고    scopus 로고
    • Apoptotic mechanism in pemphigus autoimmunoglobulins-induced acantholysis-possible involvement of the EGF receptor
    • Frusic-Zlotkin M, Raichenberg D, Wang X, David M, Michel b, Milner Y (2006) Apoptotic mechanism in pemphigus autoimmunoglobulins-induced acantholysis-possible involvement of the EGF receptor. Autoimmunity 39:563-575
    • (2006) Autoimmunity , vol.39 , pp. 563-575
    • Frusic-Zlotkin, M.1    Raichenberg, D.2    Wang, X.3    David, M.4    Michel, B.5    Milner, Y.6
  • 31
    • 0025683067 scopus 로고
    • Epidermal differentiation
    • Fuchs E (1990) Epidermal differentiation. Curr Opin Cell biol 2:1028-1035
    • (1990) Curr Opin Cell Biol , vol.2 , pp. 1028-1035
    • Fuchs, E.1
  • 32
    • 38749143649 scopus 로고    scopus 로고
    • Skin stem cells: Rising to the surface
    • Fuchs E (2008) Skin stem cells: rising to the surface. J Cell biol 180:273-284
    • (2008) J Cell Biol , vol.180 , pp. 273-284
    • Fuchs, E.1
  • 35
    • 42449141549 scopus 로고    scopus 로고
    • Regulation of dedifferentiation and redifferentiation in renal proximal tubular cells by the epidermal growth factor receptor
    • Hallman MA, Zhuang S, Schnellmann RG (2008) Regulation of dedifferentiation and redifferentiation in renal proximal tubular cells by the epidermal growth factor receptor. J Pharmacol Exp Ther 325:520-528
    • (2008) J Pharmacol Exp Ther , vol.325 , pp. 520-528
    • Hallman, M.A.1    Zhuang, S.2    Schnellmann, R.G.3
  • 37
    • 38949182962 scopus 로고    scopus 로고
    • Induction of Erbb2 by ultraviolet A irradiation: Potential role in malignant transformation of keratinocytes
    • Han CY, Lim SC, Choi HS, Kang KW (2008) Induction of Erbb2 by ultraviolet A irradiation: potential role in malignant transformation of keratinocytes. Cancer Sci 99:502-509
    • (2008) Cancer Sci , vol.99 , pp. 502-509
    • Han, C.Y.1    Lim, S.C.2    Choi, H.S.3    Kang, K.W.4
  • 39
    • 0030977565 scopus 로고    scopus 로고
    • Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development
    • Hansen LA, Alexander N, Hogan ME, Sundberg JP, Dlugosz A, Threadgill DW, Magnuson T, Yuspa SH (1997) Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. Am J Pathol 150:1959-1975
    • (1997) Am J Pathol , vol.150 , pp. 1959-1975
    • Hansen, L.A.1    Alexander, N.2    Hogan, M.E.3    Sundberg, J.P.4    Dlugosz, A.5    Threadgill, D.W.6    Magnuson, T.7    Yuspa, S.H.8
  • 40
    • 0034235628 scopus 로고    scopus 로고
    • The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors
    • Hansen LA, Woodson RL II, Holbus S, Strain K, Lo Y-C, Yuspa SH (2000) The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors. Cancer Res 60:3328-3332
    • (2000) Cancer Res , vol.60 , pp. 3328-3332
    • Hansen, L.A.1    Woodson, R.L.I.I.2    Holbus, S.3    Strain, K.4    Lo, Y.-C.5    Yuspa, S.H.6
  • 41
    • 0034543089 scopus 로고    scopus 로고
    • Regulation of keratinocyte function by growth factors
    • Hashimoto K (2000) Regulation of keratinocyte function by growth factors. J Dermatol Sci 24 (Suppl) 1:S46-S50
    • (2000) J Dermatol Sci , vol.24 , Issue.1 SUPPL.
    • Hashimoto, K.1
  • 43
    • 0029993503 scopus 로고    scopus 로고
    • UV activates growth factor receptors via reactive oxygen intermediates
    • Huang RP, Wu JX, Fan Y, Adamson ED (1996) UV activates growth factor receptors via reactive oxygen intermediates. J Cell biol 133:211-220
    • (1996) J Cell Biol , vol.133 , pp. 211-220
    • Huang, R.P.1    Wu, J.X.2    Fan, Y.3    Adamson, E.D.4
  • 44
    • 54249140899 scopus 로고    scopus 로고
    • Cellular localization of the activated EGFR determines its effect on cell growth in MDA-Mb-468 cells
    • Hyatt DC, Ceresa bP (2008) Cellular localization of the activated EGFR determines its effect on cell growth in MDA-Mb-468 cells. Exp Cell Res 314:3415-3425
    • (2008) Exp Cell Res , vol.314 , pp. 3415-3425
    • Hyatt, D.C.1    Ceresa, B.P.2
  • 45
    • 63749086305 scopus 로고    scopus 로고
    • Erbb receptors and signaling pathways in cancer
    • Hynes NE, Macdonald G (2009) Erbb receptors and signaling pathways in cancer. Curr Opin Cell biol 21:177-184
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 177-184
    • Hynes, N.E.1    Macdonald, G.2
  • 47
    • 0031238777 scopus 로고    scopus 로고
    • Specific inhibition of hair follicle formation by epidermal growth factor in an organ culture of developing mouse skin
    • Kashiwagi M, Kuroki T, Huh N (1997) Specific inhibition of hair follicle formation by epidermal growth factor in an organ culture of developing mouse skin. Dev biol 189:22-32
    • (1997) Dev Biol , vol.189 , pp. 22-32
    • Kashiwagi, M.1    Kuroki, T.2    Huh, N.3
  • 48
    • 0033992633 scopus 로고    scopus 로고
    • Biochemical and clinical implications of the Erbb/HER signaling network of growth factor receptors
    • Klapper LN, Kirschbaum MH, Sela M, Yarden Y (2000) biochemical and clinical implications of the Erbb/HER signaling network of growth factor receptors. Adv Cancer Res 77:25-79
    • (2000) Adv Cancer Res , vol.77 , pp. 25-79
    • Klapper, L.N.1    Kirschbaum, M.H.2    Sela, M.3    Yarden, Y.4
  • 49
    • 0029790979 scopus 로고    scopus 로고
    • Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
    • Knebel A, Rahmsdorf HJ, Ullrich A, Herrlich P (1996) Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. EMbO J 15:5314-5325
    • (1996) EMbO J , vol.15 , pp. 5314-5325
    • Knebel, A.1    Rahmsdorf, H.J.2    Ullrich, A.3    Herrlich, P.4
  • 50
    • 67249099003 scopus 로고    scopus 로고
    • Dynamic regulation of epithelial cell fate and barrier function by intercellular junctions
    • Koch S, Nusrat A (2009) Dynamic regulation of epithelial cell fate and barrier function by intercellular junctions. Ann NY Acad Sci 1165:220-227
    • (2009) Ann NY Acad Sci , vol.1165 , pp. 220-227
    • Koch, S.1    Nusrat, A.2
  • 51
    • 33747368155 scopus 로고    scopus 로고
    • HaCaT keratinocyte migration is dependent on epidermal growth factor receptor signaling and glycogen synthase kinase- 3alpha
    • Koivisto L, Jiang G, Hakkinen L, Chan b, Larjava H (2006) HaCaT keratinocyte migration is dependent on epidermal growth factor receptor signaling and glycogen synthase kinase- 3alpha. Exp Cell Res 312:2791-2805
    • (2006) Exp Cell Res , vol.312 , pp. 2791-2805
    • Koivisto, L.1    Jiang, G.2    Hakkinen, L.3    Chan, B.4    Larjava, H.5
  • 53
    • 38449101897 scopus 로고    scopus 로고
    • Mechanisms regulating epithelial stratification
    • Koster MI, Roop DR (2007) Mechanisms regulating epithelial stratification. Annu Rev Cell Dev biol 23:93-113
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 93-113
    • Koster, M.I.1    Roop, D.R.2
  • 56
  • 57
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • Lechler T, Fuchs E (2005) Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 437:275-280
    • (2005) Nature , vol.437 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 58
    • 0037336465 scopus 로고    scopus 로고
    • Inhibition of erbb receptor family members protects HaCaT keratinocytes from ultraviolet-b-induced apoptosis
    • Lewis DA, Zweig b, Hurwitz SA, Spandau DF (2003) Inhibition of erbb receptor family members protects HaCaT keratinocytes from ultraviolet-b-induced apoptosis. J Invest Dermatol 120:483-488
    • (2003) J Invest Dermatol , vol.120 , pp. 483-488
    • Lewis, D.A.1    Zweig, B.2    Hurwitz, S.A.3    Spandau, D.F.4
  • 59
    • 0026592283 scopus 로고
    • UVC modulation of epidermal growth factor receptor number in HeLa S3 cells
    • Ley KD, Ellem KA (1992) UVC modulation of epidermal growth factor receptor number in HeLa S3 cells. Carcinogenesis 13:183-187
    • (1992) Carcinogenesis , vol.13 , pp. 183-187
    • Ley, K.D.1    Ellem, K.A.2
  • 60
    • 66449127175 scopus 로고    scopus 로고
    • PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migration
    • Li S, Wang Q, Wang Y, Chen X, Wang Z (2009) PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migration. Mol Endocrinol 23:901-913
    • (2009) Mol Endocrinol , vol.23 , pp. 901-913
    • Li, S.1    Wang, Q.2    Wang, Y.3    Chen, X.4    Wang, Z.5
  • 62
    • 33847261640 scopus 로고    scopus 로고
    • Blockage of epidermal growth factor receptor by quinazoline tyrosine kinase inhibitors suppresses growth of human hepatocellular carcinoma
    • Liu Y, Poon RT, Shao W, Sun X, Chen H, Kok TW, Fan ST (2007) blockage of epidermal growth factor receptor by quinazoline tyrosine kinase inhibitors suppresses growth of human hepatocellular carcinoma. Cancer Lett 248:32-40
    • (2007) Cancer Lett , vol.248 , pp. 32-40
    • Liu, Y.1    Poon, R.T.2    Shao, W.3    Sun, X.4    Chen, H.5    Kok, T.W.6    Fan, S.T.7
  • 63
    • 34347211899 scopus 로고    scopus 로고
    • Erbb2 regulates inflammation and proliferation in the skin after ultraviolet irradiation
    • Madson JG, Lynch DT, Tinkum KL, Putta SK, Hansen LA (2006) Erbb2 regulates inflammation and proliferation in the skin after ultraviolet irradiation. Am J Pathol 169:1402-1414
    • (2006) Am J Pathol , vol.169 , pp. 1402-1414
    • Madson, J.G.1    Lynch, D.T.2    Tinkum, K.L.3    Putta, S.K.4    Hansen, L.A.5
  • 65
    • 0035851913 scopus 로고    scopus 로고
    • EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: Role in epithelial cell migration and carcinoma invasion
    • Mariotti A, Kedeshian PA, Dans M, Curatola AM, Gagnoux-Palacios L, Giancotti FG (2001) EGF-R signaling through Fyn kinase disrupts the function of integrin alpha6beta4 at hemidesmosomes: role in epithelial cell migration and carcinoma invasion. J Cell biol 155:447-458
    • (2001) J Cell Biol , vol.155 , pp. 447-458
    • Mariotti, A.1    Kedeshian, P.A.2    Dans, M.3    Curatola, A.M.4    Gagnoux-Palacios, L.5    Giancotti, F.G.6
  • 66
    • 0038306878 scopus 로고    scopus 로고
    • Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation
    • Mascia F, Mariani V, Girolomoni G, Pastore S (2003) blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation. Am J Pathol 163:303-312
    • (2003) Am J Pathol , vol.163 , pp. 303-312
    • Mascia, F.1    Mariani, V.2    Girolomoni, G.3    Pastore, S.4
  • 68
    • 38149076388 scopus 로고    scopus 로고
    • Hb-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development
    • Minami S, Iwamoto R, Mekada E (2008) Hb-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development. Dev Dyn 237:247-258
    • (2008) Dev Dyn , vol.237 , pp. 247-258
    • Minami, S.1    Iwamoto, R.2    Mekada, E.3
  • 69
    • 0031817827 scopus 로고    scopus 로고
    • EGFR blockade by tyrosine kinase inhibitor or monoclonal antibody inhibits growth, directs terminal differentiation and induces apoptosis in the human squamous cell carcinoma HN5
    • Modjtahedi H, Affleck K, Stubberfield C, Dean C (1998) EGFR blockade by tyrosine kinase inhibitor or monoclonal antibody inhibits growth, directs terminal differentiation and induces apoptosis in the human squamous cell carcinoma HN5. Int J Oncol 13:335-342
    • (1998) Int J Oncol , vol.13 , pp. 335-342
    • Modjtahedi, H.1    Affleck, K.2    Stubberfield, C.3    Dean, C.4
  • 70
    • 67649878206 scopus 로고    scopus 로고
    • Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma
    • Morris ZS, McClatchey AI (2009) Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma. Proc Natl Acad Sci USA 106:9767-9772
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9767-9772
    • Morris, Z.S.1    McClatchey, A.I.2
  • 71
    • 0028784049 scopus 로고
    • Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure
    • Murillas R, Larcher F, Conti CJ, Santos M, Ulrich A, Jorcano JL (1995) Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure. EMbO J 14:5216-5223
    • (1995) EMbO J , vol.14 , pp. 5216-5223
    • Murillas, R.1    Larcher, F.2    Conti, C.J.3    Santos, M.4    Ulrich, A.5    Jorcano, J.L.6
  • 72
    • 0034780526 scopus 로고    scopus 로고
    • The epidermal growth factor receptor (EGFR): Role in corneal wound healing and homeostasis 5
    • Nakamura Y, Sotozono C, Kinoshita S (2001) The epidermal growth factor receptor (EGFR): role in corneal wound healing and homeostasis 5. Exp Eye Res 72:511-517
    • (2001) Exp Eye Res , vol.72 , pp. 511-517
    • Nakamura, Y.1    Sotozono, C.2    Kinoshita, S.3
  • 75
    • 33745714456 scopus 로고    scopus 로고
    • ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors
    • Ohtsu H, Dempsey PJ, Eguchi S (2006) ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors. Am J Physiol Cell Physiol 291:C1-C10
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Ohtsu, H.1    Dempsey, P.J.2    Eguchi, S.3
  • 76
    • 0033546315 scopus 로고    scopus 로고
    • Erbb receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases
    • Olayioye MA, Beuvink I, Horsch K, Daly JM, Hynes NE (1999) Erbb receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases. J biol Chem 274:17209-17218
    • (1999) J Biol Chem , vol.274 , pp. 17209-17218
    • Olayioye, M.A.1    Beuvink, I.2    Horsch, K.3    Daly, J.M.4    Hynes, N.E.5
  • 78
    • 43749094998 scopus 로고    scopus 로고
    • The epidermal growth factor receptor system in skin repair and inflammation
    • Pastore S, Mascia F, Mariani V, Girolomoni G (2008) The epidermal growth factor receptor system in skin repair and inflammation. J Invest Dermatol 128:1365-1374
    • (2008) J Invest Dermatol , vol.128 , pp. 1365-1374
    • Pastore, S.1    Mascia, F.2    Mariani, V.3    Girolomoni, G.4
  • 79
    • 0034954124 scopus 로고    scopus 로고
    • The type III epidermal growth factor receptor mutation. biological significance and potential target for anti-cancer therapy
    • Pedersen MW, Meltorn M, Damstrup L, Poulsen HS (2001) The type III epidermal growth factor receptor mutation. biological significance and potential target for anti-cancer therapy. Ann Oncol 12:745-760
    • (2001) Ann Oncol , vol.12 , pp. 745-760
    • Pedersen, M.W.1    Meltorn, M.2    Damstrup, L.3    Poulsen, H.S.4
  • 80
    • 0042659624 scopus 로고    scopus 로고
    • Proliferation-differentiation relationships in the expression of heparin-binding epidermal growth factor-related factors and erbb receptors by normal and psoriatic human keratinocytes
    • Piepkorn M, Predd H, Underwood R, Cook P (2003) Proliferation- differentiation relationships in the expression of heparin-binding epidermal growth factor-related factors and erbb receptors by normal and psoriatic human keratinocytes. Arch Dermatol Res 295:93-101
    • (2003) Arch Dermatol Res , vol.295 , pp. 93-101
    • Piepkorn, M.1    Predd, H.2    Underwood, R.3    Cook, P.4
  • 82
    • 0142259346 scopus 로고    scopus 로고
    • The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
    • Radtke F, Raj K (2003) The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer 3:756-767
    • (2003) Nat Rev Cancer , vol.3 , pp. 756-767
    • Radtke, F.1    Raj, K.2
  • 83
    • 0037064121 scopus 로고    scopus 로고
    • Erbs-s activates Stat3 alpha in a Src- and JAK2 dependent manner
    • Ren Z., Schaefer T.S. (2002). Erbs-s activates Stat3 alpha in a Src- and JAK2 dependent manner. J. biol. Chem. 277:38486-38493
    • (2002) J. Biol. Chem. , vol.277 , pp. 38486-38493
    • Ren, Z.1    Schaefer, T.S.2
  • 88
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J (2000) Cell signaling by receptor tyrosine kinases. Cell 103:211-225
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 89
  • 90
    • 33745760717 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-mediated proliferation of enterocytes requires p21waf1/cip1 expression
    • Sheng G, Bernabe KQ, Guo J, Warner bW (2006) Epidermal growth factor receptor-mediated proliferation of enterocytes requires p21waf1/cip1 expression. Gastroenterology 131:153-164
    • (2006) Gastroenterology , vol.131 , pp. 153-164
    • Sheng, G.1    Bernabe, K.Q.2    Guo, J.3    Warner, B.W.4
  • 92
    • 26444536535 scopus 로고    scopus 로고
    • Regulating the dynamics of EGF receptor signaling in space and time
    • Shilo bZ (2005) Regulating the dynamics of EGF receptor signaling in space and time. Development 132:4017-4027
    • (2005) Development , vol.132 , pp. 4017-4027
    • Shilo, B.Z.1
  • 93
    • 0034007082 scopus 로고    scopus 로고
    • Epiregulin, a novel member of the epidermal growth factor family, is an autocrine growth factor in normal human keratinocytes
    • Shirakata Y, Komurasaki T, Toyoda H, Hanakawa Y, Yamasaki K, Tokumaru S, Sayama K, Hashimoto K (2000) Epiregulin, a novel member of the epidermal growth factor family, is an autocrine growth factor in normal human keratinocytes. J biol Chem 275:5748-5753
    • (2000) J Biol Chem , vol.275 , pp. 5748-5753
    • Shirakata, Y.1    Komurasaki, T.2    Toyoda, H.3    Hanakawa, Y.4    Yamasaki, K.5    Tokumaru, S.6    Sayama, K.7    Hashimoto, K.8
  • 95
    • 0029045856 scopus 로고
    • Strain-dependent epithelial defects in mice lacking the EGF receptor
    • Sibilia M, Wagner EF (1995) Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269:234-238
    • (1995) Science , vol.269 , pp. 234-238
    • Sibilia, M.1    Wagner, E.F.2
  • 96
    • 0033517356 scopus 로고    scopus 로고
    • Cutaneous wound healing4
    • Singer AJ, Clark RA (1999) Cutaneous wound healing4. N Engl J Med 341:738-746
    • (1999) N Engl J Med , vol.341 , pp. 738-746
    • Singer, A.J.1    Clark, R.A.2
  • 97
    • 58149288674 scopus 로고    scopus 로고
    • UV-induced EGFR signal transactivation is dependent on proligand shedding by activated metalloproteases in skin cancer cell lines
    • Singh b, Schneider M, Knyazev P, Ullrich A (2009) UV-induced EGFR signal transactivation is dependent on proligand shedding by activated metalloproteases in skin cancer cell lines. Int J Cancer 124:531-539
    • (2009) Int J Cancer , vol.124 , pp. 531-539
    • Singh, B.1    Schneider, M.2    Knyazev, P.3    Ullrich, A.4
  • 100
    • 0035947578 scopus 로고    scopus 로고
    • Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily
    • Strachan L, Murison JG, Prestidge RL, Sleeman MA, Watson JD, Kumble KD (2001) Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily. J biol Chem 276:18265-18271
    • (2001) J Biol Chem , vol.276 , pp. 18265-18271
    • Strachan, L.1    Murison, J.G.2    Prestidge, R.L.3    Sleeman, M.A.4    Watson, J.D.5    Kumble, K.D.6
  • 101
    • 23944506654 scopus 로고    scopus 로고
    • The love-hate relationship between Ras and Notch
    • Sundaram MV (2005) The love-hate relationship between Ras and Notch. Genes Dev 19:1825-1839
    • (2005) Genes Dev , vol.19 , pp. 1825-1839
    • Sundaram, M.V.1
  • 106
    • 0031656035 scopus 로고    scopus 로고
    • Human psoriatic skin in organ culture: Comparison with normal skin exposed to exogenous growth factors and effects of an antibody to the EGF receptor
    • Varani J, Kang S, Stoll S, Elder JT (1998) Human psoriatic skin in organ culture: comparison with normal skin exposed to exogenous growth factors and effects of an antibody to the EGF receptor. Pathobiology 66:253-259
    • (1998) Pathobiology , vol.66 , pp. 253-259
    • Varani, J.1    Kang, S.2    Stoll, S.3    Elder, J.T.4
  • 107
    • 70249104155 scopus 로고    scopus 로고
    • Epigenetics, stem cells and epithelial cell fate
    • Vincent A, Van SI (2009) Epigenetics, stem cells and epithelial cell fate. Differentiation 78(2-3):99-107
    • (2009) Differentiation , vol.78 , Issue.2-3 , pp. 99-107
    • Vincent, A.1    Van, S.I.2
  • 108
    • 2642532099 scopus 로고    scopus 로고
    • Differential response to keratinocyte growth factor receptor and epidermal growth factor receptor ligands of proliferating and differentiating intestinal epithelial cells
    • Visco V, Belleudi F, Marchese C, Leone L, Aimati L, Cardinali G, Kovacs D, Frati L, Torrisi MR (2004) Differential response to keratinocyte growth factor receptor and epidermal growth factor receptor ligands of proliferating and differentiating intestinal epithelial cells. J Cell Physiol 200:31-44
    • (2004) J Cell Physiol , vol.200 , pp. 31-44
    • Visco, V.1    Belleudi, F.2    Marchese, C.3    Leone, L.4    Aimati, L.5    Cardinali, G.6    Kovacs, D.7    Frati, L.8    Torrisi, M.R.9
  • 109
    • 0035289595 scopus 로고    scopus 로고
    • Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo
    • Wan YS, Wang ZQ, Shao Y, Voorhees JJ, Fisher GJ (2001) Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo. Int J Oncol 18:461-466
    • (2001) Int J Oncol , vol.18 , pp. 461-466
    • Wan, Y.S.1    Wang, Z.Q.2    Shao, Y.3    Voorhees, J.J.4    Fisher, G.J.5
  • 110
    • 0028234532 scopus 로고
    • Recombinant human betacellulin. Molecular structure, Biological activities, and receptor interaction
    • Watanabe T, Shintani A, Nakata M, Shing Y, Folkman J, Igarashi K, Sasada R (1994) Recombinant human betacellulin. Molecular structure, Biological activities, and receptor interaction. J biol Chem 269:9966-9973
    • (1994) J Biol Chem , vol.269 , pp. 9966-9973
    • Watanabe, T.1    Shintani, A.2    Nakata, M.3    Shing, Y.4    Folkman, J.5    Igarashi, K.6    Sasada, R.7
  • 112
    • 0038676258 scopus 로고    scopus 로고
    • Regulation of wound healing by growth factors and cytokines1
    • Werner S, Grose R (2003) Regulation of wound healing by growth factors and cytokines1. Physiol Rev 83:835-870
    • (2003) Physiol Rev , vol.83 , pp. 835-870
    • Werner, S.1    Grose, R.2
  • 113
    • 18044364483 scopus 로고    scopus 로고
    • Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation, apoptosis, and cell attachment
    • Woodworth CD, Michael E, Marker D, Allen S, Smith L, Nees M (2005) Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation, apoptosis, and cell attachment. Mol Cancer Ther 4:650-658
    • (2005) Mol Cancer Ther , vol.4 , pp. 650-658
    • Woodworth, C.D.1    Michael, E.2    Marker, D.3    Allen, S.4    Smith, L.5    Nees, M.6
  • 114
  • 115
    • 33748743056 scopus 로고    scopus 로고
    • Oxidative inhibition of receptor-type protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes
    • Xu Y, Shao Y, Voorhees JJ, Fisher GJ (2006) Oxidative inhibition of receptor-type protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes. J biol Chem 281:27389-27397
    • (2006) J Biol Chem , vol.281 , pp. 27389-27397
    • Xu, Y.1    Shao, Y.2    Voorhees, J.J.3    Fisher, G.J.4
  • 117
    • 36248968708 scopus 로고    scopus 로고
    • SnapShot: EGFR signaling pathway
    • Yarden Y, Shilo bZ (2007) SnapShot: EGFR signaling pathway. Cell 131:1018
    • (2007) Cell , vol.131 , pp. 1018
    • Yarden, Y.1    Shilo, B.Z.2
  • 118
    • 33845688497 scopus 로고    scopus 로고
    • Erbb receptors and epithelial-cadherin-catenin complex in human carcinomas
    • Yasmeen A, Bismar TA, Al Moustafa AE (2006) Erbb receptors and epithelial-cadherin-catenin complex in human carcinomas. Future Oncol 2:765-781
    • (2006) Future Oncol , vol.2 , pp. 765-781
    • Yasmeen, A.1    Bismar, T.A.2    Al Moustafa, A.E.3
  • 119
    • 36849049723 scopus 로고    scopus 로고
    • The role of heparin-binding EGF-like growth factor and amphiregulin in the epidermal proliferation of psoriasis in cooperation with TNFalpha
    • Yoshida A, Kanno H, Watabe D, Akasaka T, Sawai T (2008) The role of heparin-binding EGF-like growth factor and amphiregulin in the epidermal proliferation of psoriasis in cooperation with TNFalpha. Arch Dermatol Res 300:37-45
    • (2008) Arch Dermatol Res , vol.300 , pp. 37-45
    • Yoshida, A.1    Kanno, H.2    Watabe, D.3    Akasaka, T.4    Sawai, T.5
  • 120
    • 68649116693 scopus 로고    scopus 로고
    • Combined therapies for cancer: A review of EGFRtargeted monotherapy and combination treatment with other drugs
    • Zahorowska b, Crowe PJ, Yang JL (2009) Combined therapies for cancer: a review of EGFRtargeted monotherapy and combination treatment with other drugs. J Cancer Res Clin Oncol 135:1137-1148
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 1137-1148
    • Zahorowska, B.1    Crowe, P.J.2    Yang, J.L.3
  • 121
    • 3242711418 scopus 로고    scopus 로고
    • Exacerbation of psoriasis after treatment with an EGFR tyrosine kinase inhibitor
    • Zorzou MP, Stratigos A, Efstathiou E, Bamias A (2004) Exacerbation of psoriasis after treatment with an EGFR tyrosine kinase inhibitor. Acta Derm Venereol 84:308-309
    • (2004) Acta Derm Venereol , vol.84 , pp. 308-309
    • Zorzou, M.P.1    Stratigos, A.2    Efstathiou, E.3    Bamias, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.