Mammary gland specific hEGF receptor transgene expression induces neoplasia and inhibits differentiation

Oncogene

Volumn 19, Issue 17, 2000, Pages 2129-2137

  Brandt, Ralf ^a,d   Eisenbrandt, Ralf ^a,e   Leenders, Frauke ^b   Zschiesche, Wolfgang ^c   Binas, Bert ^c   Juergensen, Carola ^a   Theuring, Franz ^a,b  

^a BAYER PHARMA AG   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d NOVARTIS PHARMA AG   (Switzerland)

^e MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

Adenocarcinoma; Differentiation; Epidermal growth factor receptor; Mammary gland; Transgenic mice

Indexed keywords

ACID PROTEIN; BETA LACTOGLOBULIN; GAMMA UROGASTRONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST ADENOCARCINOMA; BREAST CANCER; BREAST DYSPLASIA; BREAST EPITHELIUM; BREAST HYPERPLASIA; CANCER GROWTH; CELL DIFFERENTIATION; CELL TRANSFORMATION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; GENE EXPRESSION; GENETIC REGULATION; LACTATION; MAMMARY GLAND; MOUSE; MULTIPLE PREGNANCY; NEOPLASM; NONHUMAN; OVARY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SALIVARY GLAND; TESTIS; TRANSGENE; TRANSGENIC MOUSE;

ANIMALIA; MOUSE MAMMARY TUMOR VIRUS; MUS MUSCULUS;

EID: 0034690033     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203520     Document Type: Article

References (42)

1. Aaronson SA. (1993). Science, 254, 1146-1153.
2. Al-Kusspooles M, Moore JH, Orringer MB and Beer DG. (1993). Int. J. Cancer, 54, 213-219.
3. Andres AC, Van der Walk MA, Schonenberger CA, Fluciger F, LeMeur M, Gerlinger P and Groner B. (1988). Genes Dev., 6, 1486-1495.
4. Archibald AL, McClenaghan M, Hornsey V, Simons JP and Clark AJ. (1990). Proc. Natl. Acad. Sci. USA, 87, 5178-5182.
5. Banerjee MR, Wood BG and Kinder DL. (1973). In Vitro Cell. Dev. Biol., 9, 129-133.
6. Barash IA, Faerman T, Ratovitsky R, Puzis M, Nathan DR, Hurwitz and Shani M. (1994). Transgenic. Res., 3, 141-151.
7. Baselga J and Mendelsohn J. (1994). Breast. Cancer Res. Treat., 29, 127-138.
8. Borg A. Baldetorp B, Ferno M, Killander D, Olsson H and Sigurdsson H. (1991). Oncogene, 6, 137-143.
9. Bouchard L, Lamarre L, Tremblay PJ and Jolicouer P. (1989). Cell, 57, 931-936.
10. Chakrabarty S, Rajagopal S and Huang S. (1995). Clin. Exp. Metastasis, 13, 191-195.
11. Chomczynski P and Sacchi N. (1987). Anal. Biochem., 162, 156-159.
12. Di Fiore PP, Pierce JH, Fleming TP, Hazan R, Ullrich A, King CR, Schlessinger J and Aaronson SA. (1987a). Cell, 51, 1063-1070.
13. Di Fiore PP, Pierce JH, Kraus MH, Segatto O, King CR and Aaronson SA. (1987b). Science, 237, 178-182.
14. Di Marco E, Pierce JH, Fleming TP, Kraus MH, Molloy CJ, Aaronson SA and Di Fiore PP. (1989). Oncogene, 4, 831-838.
15. Fan Z, Masui H, Atlas I and Mendelsohn J. (1993). Cancer Res., 53, 4322-4328.
16. Fox SB, Smith K, Hollyer J, Greenall M, Hastrich D and Harris AL. (1994). Breast Cancer Res. Treat., 29, 41-49.
17. Goldenring JR, Tsunoda Y, Stoch SA, Coffey R and Modlin IM. (1993). Regul. Pept., 43, 37-44.
18. Gramlich TL, Cohen C, Fritsch C, Derose DB and Gansler T. (1994). Am. J. Clin. Pathol., 101, 493-499.
19. Hackel PO, Zwick E, Prenzel N and Ullrich A. (1999). Curr. Opin. Cell Biol., 11, 184-189.
20. Harris AL and Nicholson S. (1987). Epidermal growth factor in breast cancer. In: Lippman ME and Dickson RB (eds). Regulatory Mechanisms in Breast Cancer. Kluwer: Boston; pp. 93-118.
21. Hennighausen L, Mcknight R, Burdon T, Baik M, Wall RJ and Smith GH. (1994). Cell Growth. Differ., 5, 607-613.
22. Hinrichs SH, Fontes JD, Bills ND and Schneider PD. (1991). Princess Takamatsu. Symp., 22, 259-274.
23. Klijn JG, Berns PM, Schmitz PI and Foekens JA. (1992). Endocr. Rev., 13, 3-17.
24. Krane IM and Leder P. (1996). Oncogene, 12, 1781-1788.
25. Lee PP, Darey KM, Shudo K and Ip MM. (1995). Endocrinol., 136, 1718-1730.
26. Liu T, Chen J and Zeng C. (1995). Chin. Med. J. Engl., 108, 653-659.
27. Matsui Y, Halter S, Holt JT, Hogan BLM and Coffey RJ. (1990). Cell, 61, 1137-1146.
28. McClenaghan M, Springbett A, Wallace RM, Wilde CJ and Clark AJ. (1995). Biochem. J., 310, 637-641.
29. Mullaney BP and Skinner MK. (1992). Mol. Endocrinol., 6, 2103-2113.
30. Muller WJ. (1991). Cancer Met. Rev., 10, 217-227.
31. Normanno N, Kim N, Wen D, Smith K, Harris AL, Plowman G, Colletta G, Ciardiello F and Salomon DS. (1995). Breast Cancer Res. Treat., 35, 293-297.
32. Rajagopal S, Huang S, Moskal TL, Lee BN, ElNaggar AK and Chakrabarty S. (1995). Int. J. Cancer, 62, 661-667.
33. Rivera EM. (1967). Methods Mammal. Embryol., 31, 442-471.
34. Salomon DS, Ciardiello F, Valverius EM and Kim N. (1991). Cancer Treat. Res., 53, 107-157.
35. Simons JP, McClenaghan M and Clark AJ. (1987). β-lactoglobulin in transgenic mice. Nature, 328, 530-532.
36. Sinn E, Muller W, Pattengale P, Tepler I, Wallace R and Leder P. (1987). Cell, 49, 465-475.
37. Spitzer E, Zschiesche W, Binas B, Grosse R and Erdmann B. (1995). J. Cell Biochem., 57, 495-508.
38. Theuring F, Aguzzi A, Kropp C, Wohn KD, Hoffmann S and Schleuning WD. (1995). Fibrinol. Proteol., 9, 277-287.
39. Tortora G, Ciardiello F, Ally S, Clair T, Salomon DS and Cho-Chung YS. (1989). FEBS Lett., 242, 363-367.
40. Whitela CBA, Archibald AA, Harris S and McClenaghan M. (1991). Transgenic. Res., 1, 3-13.
41. Yee LD, Kacinski BM and Carter D. (1989). Semin. Diagn. Pathol., 6, 110-125.
42. Yull F, Binas B, Harold G, Wallace R and Clark AJ. (1996). Transgenic Res., 6, 7-11.