-
1
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
DOI 10.1056/NEJMoa053422
-
Bonner JA, Harari PM, Giralt J et al. Radiotherapy plus cetuximab for squamous- cell carcinoma of the head and neck. N Engl J Med 2006;354:567-578. (Pubitemid 43209104)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.6
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
Cohen, R.B.6
Jones, C.U.7
Sur, R.8
Raben, D.9
Jassem, J.10
Ove, R.11
Kies, M.S.12
Baselga, J.13
Youssoufian, H.14
Amellal, N.15
Rowinsky, E.K.16
Ang, K.K.17
-
2
-
-
2342624080
-
EGFR mutations in lung, cancer: Correlation with clinical response to gefitinib therapy
-
DOI 10.1126/science.1099314
-
Paez JG, Jänne PA, Lee JC et al. EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 2004;304:1497-1500. (Pubitemid 38720929)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
3
-
-
2342471392
-
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non-Small-Cell Lung Cancer to Gefitinib
-
DOI 10.1056/NEJMoa040938
-
Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-2139. (Pubitemid 38637993)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
4
-
-
0037115674
-
Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
-
Ang KK, Berkey BA, Tu X et al. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 2002;62:7350-7356. (Pubitemid 36025259)
-
(2002)
Cancer Research
, vol.62
, Issue.24
, pp. 7350-7356
-
-
Ang, K.K.1
Berkey, B.A.2
Tu, X.3
Zhang, H.-Z.4
Katz, R.5
Hammond, E.H.6
Fu, K.K.7
Milas, L.8
-
5
-
-
0032478998
-
Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
-
Rubin Grandis J, Melhem MF, GoodingWEet al. Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998;90:824-832. (Pubitemid 28280548)
-
(1998)
Journal of the National Cancer Institute
, vol.90
, Issue.11
, pp. 824-832
-
-
Grandis, J.R.1
Melhem, M.F.2
Gooding, W.E.3
Day, R.4
Holst, V.A.5
Wagener, M.M.6
Drenning, S.D.7
Tweardy, D.J.8
-
6
-
-
47149111638
-
Distinctive E-cadherin and epidermal growth factor receptor expression in metastatic and nonmetastatic head and neck squamous cell carcinoma: Predictive and prognostic correlation
-
DOI 10.1002/cncr.23557
-
Muller S, Su L, Tighiouart M et al. Distinctive E-cadherin and epidermal growth factor receptor expression in metastatic and nonmetastatic head and neck squamous cell carcinoma: Predictive and prognostic correlation. Cancer 2008;113:97-107. (Pubitemid 351976391)
-
(2008)
Cancer
, vol.113
, Issue.1
, pp. 97-107
-
-
Muller, S.1
Su, L.2
Tighiouart, M.3
Saba, N.4
Zhang, H.5
Shin, D.M.6
Chen, Z.7
-
7
-
-
0346670259
-
A screen to identify drug resistant variants to target-directed anti-cancer agents
-
DOI 10.1251/bpo63
-
Azam M, Raz T, Nardi V et al. A screen to identify drug resistant variants to target-directed anti-cancer agents. Biol Proced Online 2003;5:204-210. (Pubitemid 38097516)
-
(2003)
Biological Procedures Online
, vol.5
, Issue.1
, pp. 204-210
-
-
Azam, M.1
Raz, T.2
Nardi, V.3
Opitz, S.L.4
Daley, G.Q.5
-
8
-
-
33847371736
-
Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors
-
Yuza Y, Glatt KA, Jiang J et al. Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors. Cancer Biol Ther 2007;6:661-667. (Pubitemid 47328344)
-
(2007)
Cancer Biology and Therapy
, vol.6
, Issue.5
, pp. 661-667
-
-
Yuza, Y.1
Glatt, K.A.2
Jiang, J.3
Greulich, H.4
Minami, Y.5
Woo, M.S.6
Shimamura, T.7
Shapiro, G.8
Lee, J.C.9
Ji, H.10
Feng, W.11
Chen, T.-H.12
Yanagisawa, H.13
Wong, K.-K.14
Meyerson, M.15
-
10
-
-
34250155320
-
Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer
-
DOI 10.1200/JCO.2006.06.6605
-
Temam S, Kawaguchi H, El-Naggar AK et al. Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer. J Clin Oncol 2007;25:2164-2170. (Pubitemid 46954638)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.16
, pp. 2164-2170
-
-
Temam, S.1
Kawaguchi, H.2
El-Naggar, A.K.3
Jelinek, J.4
Tang, H.5
Liu, D.D.6
Lang, W.7
Issa, J.-P.8
Lee, J.J.9
Mao, L.10
-
11
-
-
27244451321
-
Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
-
DOI 10.1200/JCO.2005.01.0793
-
Takano T, Ohe Y, Sakamoto H et al. Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J Clin Oncol 2005;23: 6829-6837. (Pubitemid 46260269)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.28
, pp. 6829-6837
-
-
Takano, T.1
Ohe, Y.2
Sakamoto, H.3
Tsuta, K.4
Matsuno, Y.5
Tateishi, U.6
Yamamoto, S.7
Nokihara, H.8
Yamamoto, N.9
Sekine, I.10
Kunitoh, H.11
Shibata, T.12
Sakiyama, T.13
Yoshida, T.14
Tamura, T.15
-
12
-
-
28844449401
-
Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: Molecular analysis of the IDEAL/INTACT gefitinib trials
-
DOI 10.1200/JCO.2005.02.7078
-
Bell DW, Lynch TJ, Haserlat SM et al. Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: Molecular analysis of the IDEAL/INTACT gefitinib trials. J Clin Oncol 2005;23: 8081-8092. (Pubitemid 46657411)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.31
, pp. 8081-8092
-
-
Bell, D.W.1
Lynch, T.J.2
Haserlat, S.M.3
Harris, P.L.4
Okimoto, R.A.5
Brannigan, B.W.6
Sgroi, D.C.7
Muir, B.8
Riemenschneider, M.J.9
Iacona, R.B.10
Krebs, A.D.11
Johnson, D.H.12
Giaccone, G.13
Herbst, R.S.14
Manegold, C.15
Fukuoka, M.16
Kris, M.G.17
Baselga, J.18
Ochs, J.S.19
Haber, D.A.20
more..
-
13
-
-
47549104067
-
EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: One-third of doublets occur at five pairs of amino acids
-
DOI 10.1038/onc.2008.71, PII ONC200871
-
Chen Z, Feng J, Saldivar JS et al. EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: One-third of doublets occur at five pairs of amino acids. Oncogene 2008;27:4336-4343. (Pubitemid 352010002)
-
(2008)
Oncogene
, vol.27
, Issue.31
, pp. 4336-4343
-
-
Chen, Z.1
Feng, J.2
Saldivar, J.-S.3
Gu, D.4
Bockholt, A.5
Sommer, S.S.6
-
14
-
-
20244389231
-
Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck
-
DOI 10.1158/1078-0432.CCR-04-2029
-
Lee JW, Soung YH, Kim SY et al. Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck. Clin Cancer Res 2005;11: 2879-2882. (Pubitemid 40525187)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.8
, pp. 2879-2882
-
-
Jong, W.L.1
Young, H.S.2
Su, Y.K.3
Hyo, K.N.4
Won, S.P.5
Suk, W.N.6
Min, S.K.7
Dong, I.S.8
Youn, S.L.9
Ja, J.J.10
Jung, Y.L.11
Nam, J.Y.12
Sug, H.L.13
-
15
-
-
33646154001
-
Detection of EGFR- And HER2-activating mutations in squamous cell carcinoma involving the head and neck
-
Willmore-Payne C, Holden JA, Layfield LJ. Detection of EGFR- and HER2-activating mutations in squamous cell carcinoma involving the head and neck. Mod Pathol 2006;19:634-640.
-
(2006)
Mod Pathol
, vol.19
, pp. 634-640
-
-
Willmore-Payne, C.1
Holden, J.A.2
Layfield, L.J.3
-
16
-
-
29144520704
-
Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma
-
DOI 10.1016/j.ejca.2005.08.034, PII S0959804905008737
-
Loeffler-Ragg J, Witsch-Baumgartner M, Tzankov A et al. Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma. Eur J Cancer 2006;42:109-111. (Pubitemid 41814540)
-
(2006)
European Journal of Cancer
, vol.42
, Issue.1
, pp. 109-111
-
-
Loeffler-Ragg, J.1
Witsch-Baumgartner, M.2
Tzankov, A.3
Hilbe, W.4
Schwentner, I.5
Sprinzl, G.M.6
Utermann, G.7
Zwierzina, H.8
-
17
-
-
33749035470
-
Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting
-
DOI 10.1158/1078-0432.CCR-06-0913
-
Sok JC, Coppelli FM, Thomas SM et al. Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting. Clin Cancer Res 2006;12:5064-5073. (Pubitemid 44453332)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.17
, pp. 5064-5073
-
-
Sok, J.C.1
Coppelli, F.M.2
Thomas, S.M.3
Lango, M.N.4
Xi, S.5
Hunt, J.L.6
Freilino, M.L.7
Graner, M.W.8
Wikstrand, C.J.9
Bigner, D.D.10
Gooding, W.E.11
Furnari, F.B.12
Grandis, J.R.13
-
18
-
-
50649113267
-
Is immunohistochemical epidermal growth factor receptor expression overestimated as a prognostic factor in head-neck squamous cell carcinoma? A retrospective analysis based on a tissue microarray of 365 carcinomas
-
Fischer C, Zlobec I, Stöckli E et al. Is immunohistochemical epidermal growth factor receptor expression overestimated as a prognostic factor in head-neck squamous cell carcinoma? A retrospective analysis based on a tissue microarray of 365 carcinomas. Hum Pathol 2008;39:1527-1534.
-
(2008)
Hum Pathol
, vol.39
, pp. 1527-1534
-
-
Fischer, C.1
Zlobec, I.2
Stöckli, E.3
-
19
-
-
40949124676
-
Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes
-
Seethala RR, Gooding WE, Handler PN et al. Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes. Cancer Res 2008;14:1303-1309.
-
(2008)
Cancer Res
, vol.14
, pp. 1303-1309
-
-
Seethala, R.R.1
Gooding, W.E.2
Handler, P.N.3
-
20
-
-
33846285373
-
Influence of epidermal growth factor receptor (EGFR) gene mutations on the expression of EGFR, phosphoryl-Akt, and phosphoryl-MAPK, and on the prognosis of patients with non-small cell lung cancer
-
DOI 10.1002/jso.20547
-
Sonobe M, Nakagawa M, Takenaka K et al. Influence of epidermal growth factor receptor (EGFR) gene mutations on the expression of EGFR, phosphoryl- Akt, and phosphoryl-MAPK, and on the prognosis of patients with non-small cell lung cancer. J Surg Oncol 2007;95:63-69. (Pubitemid 46122720)
-
(2007)
Journal of Surgical Oncology
, vol.95
, Issue.1
, pp. 63-69
-
-
Sonobe, M.1
Nakagawa, M.2
Takenaka, K.3
Katakura, H.4
Adachi, M.5
Yanagihara, K.6
Otake, Y.7
Wada, H.8
Tanaka, F.9
-
21
-
-
55449123441
-
Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha, and an epidermal growth factor receptor somatic mutation in patients with advanced non-squamous, non-small cell lung cancer
-
Masago K, Fujita S, Hatachi Y et al. Clinical significance of pretreatment serum amphiregulin and transforming growth factor-alpha, and an epidermal growth factor receptor somatic mutation in patients with advanced non-squamous, non-small cell lung cancer. Cancer Sci 2008;99: 2295-2301.
-
(2008)
Cancer Sci
, vol.99
, pp. 2295-2301
-
-
Masago, K.1
Fujita, S.2
Hatachi, Y.3
-
22
-
-
57149089886
-
EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan
-
Takano T, Fukui T, Ohe Y et al. EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan. J Clin Oncol 2008;26:5589-5595.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5589-5595
-
-
Takano, T.1
Fukui, T.2
Ohe, Y.3
-
23
-
-
34248358971
-
Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma
-
DOI 10.1159/000101047
-
Hoshino M, Fukui H, Ono Y et al. Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma. Pathobiology 2007;74:15-21. (Pubitemid 46742314)
-
(2007)
Pathobiology
, vol.74
, Issue.1
, pp. 15-21
-
-
Hoshino, M.1
Fukui, H.2
Ono, Y.3
Sekikawa, A.4
Ichikawa, K.5
Tomita, S.6
Imai, Y.7
Imura, J.8
Hiraishi, H.9
Fujimori, T.10
-
24
-
-
55749100008
-
Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas
-
Magkou C, Nakopoulou L, Zoubouli C et al. Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas. Breast Cancer Res 2008;10:R49.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Magkou, C.1
Nakopoulou, L.2
Zoubouli, C.3
|