MMP proteolysis of the human extracellular matrix protein aggrecan is mainly a process of normal turnover

Biochemical Journal

Volumn 446, Issue 2, 2012, Pages 213-223

  Struglics, André ^a   Hansson, Maria ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Aggrecan; Cartilage; Degradation; Matrix metalloproteinase; Proteolysis; Synovial fluid

Indexed keywords

AGGRECAN; AGGRECANASE; CHONDROITIN SULFATE; EPITOPE; KERATAN SULFATE; MONOCLONAL ANTIBODY; STROMELYSIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CARTILAGE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STRUCTURE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; KNEE INJURY; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SYNOVIAL FLUID; WESTERN BLOTTING;

ADAM PROTEINS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGGRECANS; CARTILAGE, ARTICULAR; CHONDROITIN SULFATES; EXTRACELLULAR MATRIX; HUMANS; KERATAN SULFATE; KNEE INJURIES; MATRIX METALLOPROTEINASES; MIDDLE AGED; OSTEOARTHRITIS; PEPTIDE FRAGMENTS; PROCOLLAGEN N-ENDOPEPTIDASE; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEOLYSIS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SYNOVIAL FLUID; YOUNG ADULT;

EID: 84865165620     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120274     Document Type: Article

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