Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption

Development

Volumn 128, Issue 16, 2001, Pages 3061-3070

  Feiner, L ^a   Webber, A L ^a   Brown, C B ^a   Lu, M M ^a   Jia, L ^a   Feinstein, P ^a   Mombaerts, P ^a   Epstein, J A ^a   Raper, J A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cardiac neural crest; Chemoattractant; Interrupted aortic arch; Mouse; Persistent truncus arteriosus; PlexinA2; Sema3C; Semaphorin 3C

Indexed keywords

MUTANT PROTEIN; SEMAPHORIN 3A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ARCH INTERRUPTION; ARTICLE; CARDIOVASCULAR MALFORMATION; CELL MIGRATION; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE DISRUPTION; GENE FUNCTION; GENE LOCUS; GENE TARGETING; GENETIC ANALYSIS; HEART OUTFLOW TRACT OBSTRUCTION; IN VIVO STUDY; MOUSE; MULTIGENE FAMILY; MUTAGENESIS; NEURAL CREST CELL; NEWBORN; NONHUMAN; PATENT DUCTUS ARTERIOSUS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TARGETING;

AMINO ACID SEQUENCE; ANIMALS; AORTA, THORACIC; CARRIER PROTEINS; GENOTYPE; IN SITU HYBRIDIZATION; INTEGRASES; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NERVE TISSUE PROTEINS; PHENOTYPE; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEMAPHORIN-3A; SIGNAL TRANSDUCTION; TIME FACTORS; TRUNCUS ARTERIOSUS; VIRAL PROTEINS;

EID: 0034839802     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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