메뉴 건너뛰기




Volumn 62, Issue 12, 2005, Pages 1363-1371

Plexins: Axon guidance and signal transduction

Author keywords

Axon guidance; Neuron; Plexin; R Ras; Rho; Semaphorin

Indexed keywords

EPHRIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; NETRIN; PLEXIN; RAS PROTEIN; RHO FACTOR; SEMAPHORIN;

EID: 20744434543     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-005-5018-2     Document Type: Review
Times cited : (127)

References (73)
  • 1
    • 0037032812 scopus 로고    scopus 로고
    • Molecular mechanisms of axon guidance
    • Dickson B. J. (2002) Molecular mechanisms of axon guidance. Science 298: 1959-1964
    • (2002) Science , vol.298 , pp. 1959-1964
    • Dickson, B.J.1
  • 2
    • 0033868719 scopus 로고    scopus 로고
    • Molecular basis of semaphorin-mediated axon guidance
    • Nakamura F., Kalb R. G. and Strittmatter S. M. (2000) Molecular basis of semaphorin-mediated axon guidance. J. Neurobiol. 44: 219-229
    • (2000) J. Neurobiol. , vol.44 , pp. 219-229
    • Nakamura, F.1    Kalb, R.G.2    Strittmatter, S.M.3
  • 3
    • 0027787683 scopus 로고
    • The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules
    • Kolodkin A. L., Matthes D. J. and Goodman C. S. (1993) The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules. Cell 75: 1389-1399
    • (1993) Cell , vol.75 , pp. 1389-1399
    • Kolodkin, A.L.1    Matthes, D.J.2    Goodman, C.S.3
  • 5
    • 0032546965 scopus 로고    scopus 로고
    • Collapsin-1 covalently dimerizes, and dimerization is necessary for collapsing activity
    • Koppel A. M. and Raper J. A. (1998) Collapsin-1 covalently dimerizes, and dimerization is necessary for collapsing activity. J. Biol. Chem. 273: 15708-14713
    • (1998) J. Biol. Chem. , vol.273 , pp. 15708-114713
    • Koppel, A.M.1    Raper, J.A.2
  • 6
    • 0035313110 scopus 로고    scopus 로고
    • Biological activity of soluble CD100. 1. The extracellular region of CD100 is released from the surface of T lymphocytes
    • Elhabazi A., Delaire S., Bensussan A., Boumsell L. and Bismuth G. (2001) Biological activity of soluble CD100. 1. The extracellular region of CD100 is released from the surface of T lymphocytes. J. Immunol. 166: 4341-4347
    • (2001) J. Immunol. , vol.166 , pp. 4341-4347
    • Elhabazi, A.1    Delaire, S.2    Bensussan, A.3    Boumsell, L.4    Bismuth, G.5
  • 7
    • 20244364929 scopus 로고    scopus 로고
    • Plexins are large family of receptors for transmembrane, secreted and GPI-anchored semaphorins in vertebrates
    • Tamagnone L., Artigiani S., Chen H., He Z., Ming G.-L., Song H.-J. et al. (1999) Plexins are large family of receptors for transmembrane, secreted and GPI-anchored semaphorins in vertebrates. Cell 99: 71-80
    • (1999) Cell , vol.99 , pp. 71-80
    • Tamagnone, L.1    Artigiani, S.2    Chen, H.3    He, Z.4    Ming, G.-L.5    Song, H.-J.6
  • 8
    • 1642283154 scopus 로고    scopus 로고
    • Discovery of semaphorin receptors, neuropilin and plexin, and their functions in neural development
    • Fujisawa H. (2003) Discovery of semaphorin receptors, neuropilin and plexin, and their functions in neural development. J. Neurobiol. 59: 24-33
    • (2003) J. Neurobiol. , vol.59 , pp. 24-33
    • Fujisawa, H.1
  • 9
    • 0037509860 scopus 로고    scopus 로고
    • Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family
    • Bagri A., Cheng H.-J., Yaron, A., Pleasure S. J. and Tassier-Lavigne M. (2003) Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family. Cell 113: 285-299
    • (2003) Cell , vol.113 , pp. 285-299
    • Bagri, A.1    Cheng, H.-J.2    Yaron, A.3    Pleasure, S.J.4    Tassier-Lavigne, M.5
  • 10
    • 12144285611 scopus 로고    scopus 로고
    • Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2
    • Toyofuku T., Zhang H., Kumanogoh A., Takegahara N., Suto F., Kamei J. et al. (2004) Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. Gene Dev. 18: 435-447
    • (2004) Gene Dev. , vol.18 , pp. 435-447
    • Toyofuku, T.1    Zhang, H.2    Kumanogoh, A.3    Takegahara, N.4    Suto, F.5    Kamei, J.6
  • 11
    • 10344247099 scopus 로고    scopus 로고
    • Guidance of myocardial patterning in cardiac development by Sema6D reverse signaling
    • Toyofuku T., Zhang H., Kumanogoh A., Takegahara N., Yabuki M., Harada K. et al. (2004) Guidance of myocardial patterning in cardiac development by Sema6D reverse signaling. Nat. Cell Biol. 6: 1204-1211
    • (2004) Nat. Cell Biol. , vol.6 , pp. 1204-1211
    • Toyofuku, T.1    Zhang, H.2    Kumanogoh, A.3    Takegahara, N.4    Yabuki, M.5    Harada, K.6
  • 12
    • 1242351777 scopus 로고    scopus 로고
    • Biological functions and signaling of a tranmembrane semaphorin, CD100/Sema4D
    • Kumanogoh A. and Kikutani H. (2004) Biological functions and signaling of a tranmembrane semaphorin, CD100/Sema4D. Cell. Mol. Life Sci. 61: 292-300
    • (2004) Cell. Mol. Life Sci. , vol.61 , pp. 292-300
    • Kumanogoh, A.1    Kikutani, H.2
  • 13
    • 0141885133 scopus 로고    scopus 로고
    • The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion
    • Moreau-Fauvarque C., Kumanogoh A., Camand E., Jaillard C., Barbin G., Boquet I. et al. (2003) The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion. J. Neurosci. 23: 9229-9239
    • (2003) J. Neurosci. , vol.23 , pp. 9229-9239
    • Moreau-Fauvarque, C.1    Kumanogoh, A.2    Camand, E.3    Jaillard, C.4    Barbin, G.5    Boquet, I.6
  • 14
    • 0037014472 scopus 로고    scopus 로고
    • Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology
    • Swierz J. M., Kuner R., Behrens J. and Offermanns S. (2002) Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology. Neuron 35: 51-63
    • (2002) Neuron , vol.35 , pp. 51-63
    • Swierz, J.M.1    Kuner, R.2    Behrens, J.3    Offermanns, S.4
  • 15
    • 0037044715 scopus 로고    scopus 로고
    • Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF
    • Perrot V., Vazquez-Prado J. and Gutkind J. S. (2002) Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF. J. Biol. Chem. 277: 43115-43120
    • (2002) J. Biol. Chem. , vol.277 , pp. 43115-43120
    • Perrot, V.1    Vazquez-Prado, J.2    Gutkind, J.S.3
  • 17
    • 2542609986 scopus 로고    scopus 로고
    • An oligodendrocyte lineage-specific semaphorin, Sema5A, inhibits axon growth by retinal ganglion cells
    • Goldberg J. L., Vargas M. E., Wang J. T., Mandemakers W., Oster S. F., Sretavan D. W. et al. (2004) An oligodendrocyte lineage-specific semaphorin, Sema5A, inhibits axon growth by retinal ganglion cells. J. Neurosci. 24: 4989-4999
    • (2004) J. Neurosci. , vol.24 , pp. 4989-4999
    • Goldberg, J.L.1    Vargas, M.E.2    Wang, J.T.3    Mandemakers, W.4    Oster, S.F.5    Sretavan, D.W.6
  • 18
    • 0043033220 scopus 로고    scopus 로고
    • Semaphorin 7A promotes axon outgrowth integrins and MAPKs
    • Pasterkamp R. J., Peschon J. J., Spriggs M. K. and Kolodkin A. L. (2003) Semaphorin 7A promotes axon outgrowth integrins and MAPKs. Nature 424: 398-405
    • (2003) Nature , vol.424 , pp. 398-405
    • Pasterkamp, R.J.1    Peschon, J.J.2    Spriggs, M.K.3    Kolodkin, A.L.4
  • 19
    • 4344594556 scopus 로고    scopus 로고
    • PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development
    • Gitler A. D., Lu M. M. and Epstein J. A. (2004) PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev. Cell 7: 107-116
    • (2004) Dev. Cell , vol.7 , pp. 107-116
    • Gitler, A.D.1    Lu, M.M.2    Epstein, J.A.3
  • 21
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. (1998) Rho GTPases and the actin cytoskeleton. Science 279: 509-514
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 22
    • 0036684178 scopus 로고    scopus 로고
    • Rho family GTPases as key regulators for neuronal network formation
    • Negishi M. and Katoh H. (2002) Rho family GTPases as key regulators for neuronal network formation. J. Biochem. 132: 157-166
    • (2002) J. Biochem. , vol.132 , pp. 157-166
    • Negishi, M.1    Katoh, H.2
  • 23
    • 0028961293 scopus 로고
    • Rho, rac and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia and filopodia
    • Nobes C. D. and Hall A. (1995) Rho, rac and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia and filopodia. Cell 81: 53-62
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 24
    • 0031027205 scopus 로고    scopus 로고
    • Rho family GTPases and neuronal growth cone remodeling: Relationship between increased complexity induced Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid
    • Kozuma R., Sarner S., Ahmed S. and Lim L. (1997) Rho family GTPases and neuronal growth cone remodeling: relationship between increased complexity induced Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid. Mol. Cell. Biol. 17: 1201-1211
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1201-1211
    • Kozuma, R.1    Sarner, S.2    Ahmed, S.3    Lim, L.4
  • 25
    • 0032579378 scopus 로고    scopus 로고
    • p160 RhoA-binding kinase ROKα induces neurite retraction
    • Katoh H., Aoki J., Ichikawa A. and Negishi M. (1998) p160 RhoA-binding kinase ROKα induces neurite retraction. J. Biol. Chem. 273: 2489-2492
    • (1998) J. Biol. Chem. , vol.273 , pp. 2489-2492
    • Katoh, H.1    Aoki, J.2    Ichikawa, A.3    Negishi, M.4
  • 26
    • 0033835027 scopus 로고    scopus 로고
    • Small GTPase RhoG is a key regulator for neurite outgrowth in PC12 cells
    • Katoh H., Yasui H., Yamaguchi Y., Aoki J., Fujita H., Mori K. et al. (2000) Small GTPase RhoG is a key regulator for neurite outgrowth in PC12 cells. Mol. Cell. Biol. 20: 7378-7387
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7378-7387
    • Katoh, H.1    Yasui, H.2    Yamaguchi, Y.3    Aoki, J.4    Fujita, H.5    Mori, K.6
  • 27
    • 0042674398 scopus 로고    scopus 로고
    • RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
    • Katoh H. and Negishi M. (2003) RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature 424: 461-464
    • (2003) Nature , vol.424 , pp. 461-464
    • Katoh, H.1    Negishi, M.2
  • 28
    • 0347379829 scopus 로고    scopus 로고
    • A role of Rnd1 GTPase in dendritic spine formation in hippocampal neurons
    • Ishikawa Y., Katoh H. and Negishi M. (2003) A role of Rnd1 GTPase in dendritic spine formation in hippocampal neurons. J. Neurosci. 23: 11065-11072
    • (2003) J. Neurosci. , vol.23 , pp. 11065-11072
    • Ishikawa, Y.1    Katoh, H.2    Negishi, M.3
  • 29
    • 0037160026 scopus 로고    scopus 로고
    • Rapostlin is a novel effector of Rnd2 GTPase inducing neurite branching
    • Fujita H., Katoh H., Ishikawa Y., Mori K. and Negishi M. (2002) Rapostlin is a novel effector of Rnd2 GTPase inducing neurite branching. J. Biol. Chem. 277: 45428-45434
    • (2002) J. Biol. Chem. , vol.277 , pp. 45428-45434
    • Fujita, H.1    Katoh, H.2    Ishikawa, Y.3    Mori, K.4    Negishi, M.5
  • 30
    • 0034212667 scopus 로고    scopus 로고
    • The small GTP-binding protein TC10 promotes nerve elongation in neuronal cells, and its expression is induced during nerve regeneration in rats
    • Tanabe K., Tachibana T. Yamashita T., Che Y. H., Yoneda Y., Ochi T. et al. (2000) The small GTP-binding protein TC10 promotes nerve elongation in neuronal cells, and its expression is induced during nerve regeneration in rats. J. Neurosci. 20: 4138-4144
    • (2000) J. Neurosci. , vol.20 , pp. 4138-4144
    • Tanabe, K.1    Tachibana, T.2    Yamashita, T.3    Che, Y.H.4    Yoneda, Y.5    Ochi, T.6
  • 31
    • 0030809301 scopus 로고    scopus 로고
    • Rac1 mediates collapsing-1-induced growth cone collapse
    • Jin Z. and Strittmatter S. M. (1997) Rac1 mediates collapsing-1-induced growth cone collapse. J. Neurosci. 17: 6256-6263
    • (1997) J. Neurosci. , vol.17 , pp. 6256-6263
    • Jin, Z.1    Strittmatter, S.M.2
  • 32
    • 0033560132 scopus 로고    scopus 로고
    • Myelin and collapin-1 induce motor neuron growth cone collapse through different pathways: Inhibition of collapse by opposing mutants of rac1
    • Kuhn T. B., Brown M. D., Wilcox C. L., Raper J. A. and Bamburg J. R. (1999) Myelin and collapin-1 induce motor neuron growth cone collapse through different pathways: inhibition of collapse by opposing mutants of rac1. J. Neurosci. 19: 1965-1975
    • (1999) J. Neurosci. , vol.19 , pp. 1965-1975
    • Kuhn, T.B.1    Brown, M.D.2    Wilcox, C.L.3    Raper, J.A.4    Bamburg, J.R.5
  • 33
    • 4043105621 scopus 로고    scopus 로고
    • The activity of the Plexin-A1 receptor is regulated by Rac
    • Turner L. J., Nicholls S. and Hall A. (2004) The activity of the Plexin-A1 receptor is regulated by Rac. J. Biol. Chem. 279: 33199-33205
    • (2004) J. Biol. Chem. , vol.279 , pp. 33199-33205
    • Turner, L.J.1    Nicholls, S.2    Hall, A.3
  • 34
    • 0037101649 scopus 로고    scopus 로고
    • Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapse
    • Jurney W. M., Gallo G., Letourneau P. C. and McLoon S. C. (2002) Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapse. J. Neuosci. 22: 6019-6028
    • (2002) J. Neuosci. , vol.22 , pp. 6019-6028
    • Jurney, W.M.1    Gallo, G.2    Letourneau, P.C.3    McLoon, S.C.4
  • 36
    • 0029132912 scopus 로고
    • Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33
    • Goshima Y., Nakamura F., Strittmatter P. and Strittmatter S. M. (1995) Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33. Nature 276: 509-514
    • (1995) Nature , vol.276 , pp. 509-514
    • Goshima, Y.1    Nakamura, F.2    Strittmatter, P.3    Strittmatter, S.M.4
  • 37
    • 0034282891 scopus 로고    scopus 로고
    • Identification of CRAM, a novel unc-33 gene family protein that associates with CRMP3 and protein-tyrosine kinase(s) in the developing rat brain
    • Inatomi R., Tsujimura T., Hitomi T., Mitsui N., Hermann P., Kuroda S. et al. (2000) Identification of CRAM, a novel unc-33 gene family protein that associates with CRMP3 and protein-tyrosine kinase(s) in the developing rat brain. J. Biol. Chem. 275: 27291-27302
    • (2000) J. Biol. Chem. , vol.275 , pp. 27291-27302
    • Inatomi, R.1    Tsujimura, T.2    Hitomi, T.3    Mitsui, N.4    Hermann, P.5    Kuroda, S.6
  • 38
    • 18644374595 scopus 로고    scopus 로고
    • Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex
    • Sasaki Y., Cheng C., Uchida Y., Nakajima O., Ohshima T., Yagi T. et al. (2002) Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex. Neuron 35: 907-920
    • (2002) Neuron , vol.35 , pp. 907-920
    • Sasaki, Y.1    Cheng, C.2    Uchida, Y.3    Nakajima, O.4    Ohshima, T.5    Yagi, T.6
  • 39
    • 5644276320 scopus 로고    scopus 로고
    • α2-Chimaerin, cyclin-dependent kinase 5/p35 and its target collapsing response mediator protein-2 are essential components in semaphorin 3A-induced growth cone collapse
    • Brown M., Jacobs T., Eickholt B., Ferrari G., Teo M., Monfries C. et al. (2004) α2-Chimaerin, cyclin-dependent kinase 5/p35 and its target collapsing response mediator protein-2 are essential components in semaphorin 3A-induced growth cone collapse. J. Neuorsci. 24: 8994-9004
    • (2004) J. Neuorsci. , vol.24 , pp. 8994-9004
    • Brown, M.1    Jacobs, T.2    Eickholt, B.3    Ferrari, G.4    Teo, M.5    Monfries, C.6
  • 40
    • 0037092042 scopus 로고    scopus 로고
    • An inactive pool of GSK-3 at the leading edge of growth cones is implicated in semaphorin 3A signaling
    • Eickholt B., Walsh S. and Doherty P. (2002) An inactive pool of GSK-3 at the leading edge of growth cones is implicated in semaphorin 3A signaling. J. Cell Biol. 157: 211-217
    • (2002) J. Cell Biol. , vol.157 , pp. 211-217
    • Eickholt, B.1    Walsh, S.2    Doherty, P.3
  • 43
    • 0037188897 scopus 로고    scopus 로고
    • MICALs, a family of conserved flavoprotein oxidoreductases, function in Plexin-mediated axonal repulsion
    • Terman J. R., Mao T., Pasterkamp R. J., Yu H.-H. and Kolodkin A. (2002) MICALs, a family of conserved flavoprotein oxidoreductases, function in Plexin-mediated axonal repulsion. Cell 109: 887-900
    • (2002) Cell , vol.109 , pp. 887-900
    • Terman, J.R.1    Mao, T.2    Pasterkamp, R.J.3    Yu, H.-H.4    Kolodkin, A.5
  • 44
    • 0037096385 scopus 로고    scopus 로고
    • Growth cone collapse induced by semaphorin 3A requires 12/15-lipoxygenase
    • Mikule K., Gatlin J. C., Houssaye B. A. and Pfenninger K. H. (2002) Growth cone collapse induced by semaphorin 3A requires 12/15-lipoxygenase. J. Neurosci. 22: 4932-4941
    • (2002) J. Neurosci. , vol.22 , pp. 4932-4941
    • Mikule, K.1    Gatlin, J.C.2    Houssaye, B.A.3    Pfenninger, K.H.4
  • 45
    • 0034550281 scopus 로고    scopus 로고
    • The semaphorin 3A receptor may directly regulate the activity of small GTPases
    • Rohm B., Rahim B., Kleiber B., Hovatta I. and Püschel A. W. (2000) The semaphorin 3A receptor may directly regulate the activity of small GTPases. FEBS Lett. 486: 68-72
    • (2000) FEBS Lett. , vol.486 , pp. 68-72
    • Rohm, B.1    Rahim, B.2    Kleiber, B.3    Hovatta, I.4    Püschel, A.W.5
  • 46
    • 0033739987 scopus 로고    scopus 로고
    • The semaphoring receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner
    • Vikis H., Li W., He Z. and Guan K.-L. (2000) The semaphoring receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner. Proc. Natl. Acad. Sci. USA 97: 12457-12462
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12457-12462
    • Vikis, H.1    Li, W.2    He, Z.3    Guan, K.-L.4
  • 47
    • 0035814887 scopus 로고    scopus 로고
    • Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho
    • Driessens M. H. E., Hu H., Nobes C. D., Self A., Jordens I., Goodman C. S. et al. (2001) Plexin-B semaphorin receptors interact directly with active Rac and regulate the actin cytoskeleton by activating Rho. Curr. Biol. 11: 339-344
    • (2001) Curr. Biol. , vol.11 , pp. 339-344
    • Driessens, M.H.E.1    Hu, H.2    Nobes, C.D.3    Self, A.4    Jordens, I.5    Goodman, C.S.6
  • 48
    • 0034783680 scopus 로고    scopus 로고
    • Plexin B mediates axon guidance in Drosophila by simultaneously inhibiting active Rac and enhancing RhoA signaling
    • Hu H., Marton T. F. and Goodman C. S. (2001) Plexin B mediates axon guidance in Drosophila by simultaneously inhibiting active Rac and enhancing RhoA signaling. Neuron 32: 39-51
    • (2001) Neuron , vol.32 , pp. 39-51
    • Hu, H.1    Marton, T.F.2    Goodman, C.S.3
  • 49
    • 0036206649 scopus 로고    scopus 로고
    • The Plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding
    • Vikis H. G., Li W. and Guan K.-L. (2002) The Plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding. Gene Dev. 16: 836-845
    • (2002) Gene Dev. , vol.16 , pp. 836-845
    • Vikis, H.G.1    Li, W.2    Guan, K.-L.3
  • 50
    • 0037126064 scopus 로고    scopus 로고
    • The semaphoring receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG
    • Aurandt J., Vikis H. G., Gutkind J. S., Ahn N. and Guan K.-L. (2002) The semaphoring receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG. Proc. Natl. Acad. Sci. USA 99: 12085-12090
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12085-12090
    • Aurandt, J.1    Vikis, H.G.2    Gutkind, J.S.3    Ahn, N.4    Guan, K.-L.5
  • 53
    • 0035952680 scopus 로고    scopus 로고
    • RGS-containing RhoGEFs: The missing link between transforming G proteins and Rho
    • Fukuhara S., Chikumi H. and Gutkind J. S. (2001) RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho. Oncogene 20: 1661-1068
    • (2001) Oncogene , vol.20 , pp. 1661-11068
    • Fukuhara, S.1    Chikumi, H.2    Gutkind, J.S.3
  • 54
    • 0035150402 scopus 로고    scopus 로고
    • Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells
    • Fukata Y., Amano M. and Kaibuchi K. (2001) Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends Pharm. Sci. 22: 32-39
    • (2001) Trends Pharm. Sci. , vol.22 , pp. 32-39
    • Fukata, Y.1    Amano, M.2    Kaibuchi, K.3
  • 55
    • 0038491273 scopus 로고    scopus 로고
    • Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells
    • Oinuma I., Katoh H., Harada A. and Negishi M. (2003) Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells. J. Biol. Chem. 278: 25671-25777
    • (2003) J. Biol. Chem. , vol.278 , pp. 25671-25777
    • Oinuma, I.1    Katoh, H.2    Harada, A.3    Negishi, M.4
  • 56
    • 0032489841 scopus 로고    scopus 로고
    • A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion
    • Nobes C. D., Lauritzen L. Mattei M. G., Paris S., Hall A. and Chardin P. (1998) A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion. J. Cell Biol. 141: 187-197
    • (1998) J. Cell Biol. , vol.141 , pp. 187-197
    • Nobes, C.D.1    Lauritzen, L.2    Mattei, M.G.3    Paris, S.4    Hall, A.5    Chardin, P.6
  • 57
    • 3042546082 scopus 로고    scopus 로고
    • Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2
    • Swierz J. M., Kuner R. and Offermanns S. (2004) Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2. J. Cell Biol. 165: 869-880
    • (2004) J. Cell Biol. , vol.165 , pp. 869-880
    • Swierz, J.M.1    Kuner, R.2    Offermanns, S.3
  • 60
    • 3843065433 scopus 로고    scopus 로고
    • The semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras
    • Oinuma I., Ishikawa Y., Katoh H. and Negishi M. (2004) The semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras. Science 305: 862-865
    • (2004) Science , vol.305 , pp. 862-865
    • Oinuma, I.1    Ishikawa, Y.2    Katoh, H.3    Negishi, M.4
  • 61
    • 0037080330 scopus 로고    scopus 로고
    • Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in semaphorin 3A-induced cytoskeletal collapse
    • Zanata S. M., Hovatta I., Rohm B. and Püschel A. W. (2002) Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in semaphorin 3A-induced cytoskeletal collapse. J. Neurosci. 22: 471-477
    • (2002) J. Neurosci. , vol.22 , pp. 471-477
    • Zanata, S.M.1    Hovatta, I.2    Rohm, B.3    Püschel, A.W.4
  • 63
    • 0034279107 scopus 로고    scopus 로고
    • Regulation of neurite outgrowth by integrin activation
    • Ivins J. K., Yurchenco P. D. and Lander A. D. (2000) Regulation of neurite outgrowth by integrin activation. J. Neurosci. 20: 6551-6560
    • (2000) J. Neurosci. , vol.20 , pp. 6551-6560
    • Ivins, J.K.1    Yurchenco, P.D.2    Lander, A.D.3
  • 66
    • 0041530325 scopus 로고    scopus 로고
    • Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function
    • Serini G., Valdembri D., Zanivan S., Morterra G., Burkhardt C., Caccavari F. et al. (2003) Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature 424: 391-397
    • (2003) Nature , vol.424 , pp. 391-397
    • Serini, G.1    Valdembri, D.2    Zanivan, S.3    Morterra, G.4    Burkhardt, C.5    Caccavari, F.6
  • 67
    • 2442421626 scopus 로고    scopus 로고
    • Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility
    • Barberis D., Artigiani S., Casazza A., Corso S., Giordano S., Love C. A. et al. (2004) Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility. FASEB J. 18: 592-594
    • (2004) FASEB J. , vol.18 , pp. 592-594
    • Barberis, D.1    Artigiani, S.2    Casazza, A.3    Corso, S.4    Giordano, S.5    Love, C.A.6
  • 68
    • 10644250013 scopus 로고    scopus 로고
    • Molecular dissection of the semaphorin 4D receptor Plexin-B1-stimulated R-Ras GTPase activating protein acitivity and neurite remodeling in hippocampal neurons
    • Oinuma I., Katoh H. and Negishi M. (2004) Molecular dissection of the semaphorin 4D receptor Plexin-B1-stimulated R-Ras GTPase activating protein acitivity and neurite remodeling in hippocampal neurons. J. Neurosci. 24: 11473-11480
    • (2004) J. Neurosci. , vol.24 , pp. 11473-11480
    • Oinuma, I.1    Katoh, H.2    Negishi, M.3
  • 69
    • 3042796979 scopus 로고    scopus 로고
    • GAP control: Regulating the regulators of small GTPases
    • Bernards A. and Settleman J. (2004) GAP control: regulating the regulators of small GTPases. Trends Cell Biol. 14: 377-385
    • (2004) Trends Cell Biol. , vol.14 , pp. 377-385
    • Bernards, A.1    Settleman, J.2
  • 70
    • 0033152924 scopus 로고    scopus 로고
    • Signal transduction underlying growth cone guidance by diffusible factors
    • Song H.-J. and Poo M.-M. (1999) Signal transduction underlying growth cone guidance by diffusible factors. Curr. Opin. Neurobiol. 9: 355-363
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 355-363
    • Song, H.-J.1    Poo, M.-M.2
  • 71
    • 1242284592 scopus 로고    scopus 로고
    • Nervy links protein kinase a to Plexin-mediated semaphorin repulsion
    • Terman J. R. and Kolodkin A. L. (2004) Nervy links protein kinase A to Plexin-mediated semaphorin repulsion. Science 303: 1204-1207
    • (2004) Science , vol.303 , pp. 1204-1207
    • Terman, J.R.1    Kolodkin, A.L.2
  • 72
    • 0034611809 scopus 로고    scopus 로고
    • Semaphorin 3A is a chamoattractant for cortical apical dendrites
    • Polleux F., Morrow T. and Ghosh A. (2000) Semaphorin 3A is a chamoattractant for cortical apical dendrites. Nature 404: 567-573
    • (2000) Nature , vol.404 , pp. 567-573
    • Polleux, F.1    Morrow, T.2    Ghosh, A.3
  • 73
    • 2442516485 scopus 로고    scopus 로고
    • To move or not to move?
    • Tamagnone L. and Comoglio P. M. (2004) To move or not to move? EMBO Rep. 5: 356-361
    • (2004) EMBO Rep. , vol.5 , pp. 356-361
    • Tamagnone, L.1    Comoglio, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.