Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 4, 2011, Pages 741-749

  Casazza, Andrea ^a   Fu, Xi ^b   Johansson, Irja ^b   Capparuccia, Lorena ^a   Andersson, Fredrik ^b   Giustacchini, Alice ^c,d   Squadrito, Mario Leonardo ^c,d   Venneri, Mary Anna ^c   Mazzone, Massimiliano ^e,f   Larsson, Erik ^b   Carmeliet, Peter ^e,f   De Palma, Michele ^c   Naldini, Luigi ^c,d   Tamagnone, Luca ^a   Rolny, Charlotte ^a,b  

^a UNIVERSITY OF TURIN   (Italy)

^b UPPSALA UNIVERSITY   (Sweden)

^c SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^d VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^e DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^f UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

angiogenesis; metastasis; molecular biology; neuropilin; pathology; receptors; semaphorin; tumor; vascular biology

Indexed keywords

ANGIOPOIETIN RECEPTOR; NEUROPILIN 1; SEMAPHORIN 3A;

ANGIOGENESIS; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL FUNCTION; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL MIGRATION; CONTROLLED STUDY; GENE TARGETING; GENE TRANSFER; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; MONOCYTE; MOUSE; NONHUMAN; PRIMARY TUMOR; PRIORITY JOURNAL; TUMOR ANGIOGENESIS; TUMOR NECROSIS;

ANIMALS; BREAST NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; GENE THERAPY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; NECROSIS; NEOVASCULARIZATION, PATHOLOGIC; NEUROPILIN-1; PARACRINE COMMUNICATION; RECEPTOR, TIE-2; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; SEMAPHORIN-3A; SIGNAL TRANSDUCTION; STEM CELLS; STROMAL CELLS; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79953751395     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.211920     Document Type: Article

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