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Volumn 23, Issue 4-5, 2012, Pages 207-214

The role of cytokines in the pathogenesis and treatment of HIV infection

Author keywords

CD4 and CD8 T cell immune activation; IL 7; T cell homeostasis; Type I IFN

Indexed keywords

ALPHA INTERFERON; CD14 ANTIGEN; CYTOKINE; D DIMER; INTERFERON; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 7; VIRUS RNA; ZIDOVUDINE;

EID: 84864924083     PISSN: 13596101     EISSN: 18790305     Source Type: Journal    
DOI: 10.1016/j.cytogfr.2012.05.007     Document Type: Article
Times cited : (77)

References (106)
  • 1
  • 3
    • 4644289983 scopus 로고    scopus 로고
    • Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract
    • Mehandru S., Poles M.A., Tenner-Racz K., Horowitz A., Hurley A., Hogan C., et al. Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract. The Journal of Experimental Medicine 2004, 200:761-770.
    • (2004) The Journal of Experimental Medicine , vol.200 , pp. 761-770
    • Mehandru, S.1    Poles, M.A.2    Tenner-Racz, K.3    Horowitz, A.4    Hurley, A.5    Hogan, C.6
  • 4
    • 17844376742 scopus 로고    scopus 로고
    • Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells
    • Li Q., Duan L., Estes J.D., Ma Z.M., Rourke T., Wang Y., et al. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature 2005, 434:1148-1152.
    • (2005) Nature , vol.434 , pp. 1148-1152
    • Li, Q.1    Duan, L.2    Estes, J.D.3    Ma, Z.M.4    Rourke, T.5    Wang, Y.6
  • 5
    • 17844374605 scopus 로고    scopus 로고
    • Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
    • Mattapallil J.J., Douek D.C., Hill B., Nishimura Y., Martin M., Roederer M. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 2005, 434:1093-1097.
    • (2005) Nature , vol.434 , pp. 1093-1097
    • Mattapallil, J.J.1    Douek, D.C.2    Hill, B.3    Nishimura, Y.4    Martin, M.5    Roederer, M.6
  • 6
    • 0026011260 scopus 로고
    • Few infected CD4+ T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection
    • Brinchmann J.E., Albert J., Vartdal F. Few infected CD4+ T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection. Journal of Virology 1991, 65:2019-2023.
    • (1991) Journal of Virology , vol.65 , pp. 2019-2023
    • Brinchmann, J.E.1    Albert, J.2    Vartdal, F.3
  • 8
    • 0030913366 scopus 로고    scopus 로고
    • Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
    • Chun T.W., Carruth L., Finzi D., Shen X., DiGiuseppe J.A., Taylor H., et al. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 1997, 387:183-188.
    • (1997) Nature , vol.387 , pp. 183-188
    • Chun, T.W.1    Carruth, L.2    Finzi, D.3    Shen, X.4    DiGiuseppe, J.A.5    Taylor, H.6
  • 9
    • 0032971372 scopus 로고    scopus 로고
    • Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues
    • Haase A.T. Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues. Annual Review of Immunology 1999, 17:625-656.
    • (1999) Annual Review of Immunology , vol.17 , pp. 625-656
    • Haase, A.T.1
  • 10
    • 0020516865 scopus 로고
    • Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome
    • Lane H.C., Masur H., Edgar L.C., Whalen G., Rook A.H., Fauci A.S. Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. The New England Journal of Medicine 1983, 309:453-458.
    • (1983) The New England Journal of Medicine , vol.309 , pp. 453-458
    • Lane, H.C.1    Masur, H.2    Edgar, L.C.3    Whalen, G.4    Rook, A.H.5    Fauci, A.S.6
  • 11
    • 0022314094 scopus 로고
    • Immunologic abnormalities in the acquired immunodeficiency syndrome
    • Lane H.C., Fauci A.S. Immunologic abnormalities in the acquired immunodeficiency syndrome. Annual Review of Immunology 1985, 3:477-500.
    • (1985) Annual Review of Immunology , vol.3 , pp. 477-500
    • Lane, H.C.1    Fauci, A.S.2
  • 13
    • 0032955651 scopus 로고    scopus 로고
    • Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage
    • Giorgi J.V., Hultin L.E., McKeating J.A., Johnson T.D., Owens B., Jacobson L.P., et al. Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. The Journal of Infectious Diseases 1999, 179:859-870.
    • (1999) The Journal of Infectious Diseases , vol.179 , pp. 859-870
    • Giorgi, J.V.1    Hultin, L.E.2    McKeating, J.A.3    Johnson, T.D.4    Owens, B.5    Jacobson, L.P.6
  • 15
    • 3843056825 scopus 로고    scopus 로고
    • Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load
    • Deeks S.G., Kitchen C.M., Liu L., Guo H., Gascon R., Narvaez A.B., et al. Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood 2004, 104:942-947.
    • (2004) Blood , vol.104 , pp. 942-947
    • Deeks, S.G.1    Kitchen, C.M.2    Liu, L.3    Guo, H.4    Gascon, R.5    Narvaez, A.B.6
  • 16
    • 4043102575 scopus 로고    scopus 로고
    • CD8+ T cells specific for EBV, cytomegalovirus, and influenza virus are activated during primary HIV infection
    • Doisne J.M., Urrutia A., Lacabaratz-Porret C., Goujard C., Meyer L., Chaix M.L., et al. CD8+ T cells specific for EBV, cytomegalovirus, and influenza virus are activated during primary HIV infection. Journal of Immunology 2004, 173:2410-2418.
    • (2004) Journal of Immunology , vol.173 , pp. 2410-2418
    • Doisne, J.M.1    Urrutia, A.2    Lacabaratz-Porret, C.3    Goujard, C.4    Meyer, L.5    Chaix, M.L.6
  • 17
    • 27744523526 scopus 로고    scopus 로고
    • NK cells in HIV infection: paradigm for protection or targets for ambush
    • Fauci A.S., Mavilio D., Kottilil S. NK cells in HIV infection: paradigm for protection or targets for ambush. Nature Reviews 2005, 5:835-843.
    • (2005) Nature Reviews , vol.5 , pp. 835-843
    • Fauci, A.S.1    Mavilio, D.2    Kottilil, S.3
  • 18
    • 20544475417 scopus 로고    scopus 로고
    • Viral and host factors in the pathogenesis of HIV infection
    • Derdeyn C.A., Silvestri G. Viral and host factors in the pathogenesis of HIV infection. Current Opinion in Immunology 2005, 17:366-373.
    • (2005) Current Opinion in Immunology , vol.17 , pp. 366-373
    • Derdeyn, C.A.1    Silvestri, G.2
  • 19
  • 24
    • 0031873665 scopus 로고    scopus 로고
    • Limited CD4+T-cell renewal in early HIV-1 infection: effect of highly active antiretroviral therapy
    • Fleury S., de Boer R.J., Rizzardi G.P., Wolthers K.C., Otto S.A., Welbon C.C., et al. Limited CD4+T-cell renewal in early HIV-1 infection: effect of highly active antiretroviral therapy. Nature Medicine 1998, 4:794-801.
    • (1998) Nature Medicine , vol.4 , pp. 794-801
    • Fleury, S.1    de Boer, R.J.2    Rizzardi, G.P.3    Wolthers, K.C.4    Otto, S.A.5    Welbon, C.C.6
  • 30
    • 35448976736 scopus 로고    scopus 로고
    • Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys
    • Gordon S.N., Klatt N.R., Bosinger S.E., Brenchley J.M., Milush J.M., Engram J.C., et al. Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys. Journal of Immunology 2007, 179:3026-3034.
    • (2007) Journal of Immunology , vol.179 , pp. 3026-3034
    • Gordon, S.N.1    Klatt, N.R.2    Bosinger, S.E.3    Brenchley, J.M.4    Milush, J.M.5    Engram, J.C.6
  • 33
    • 55949084601 scopus 로고    scopus 로고
    • Inflammatory and coagulation biomarkers and mortality in patients with HIV infection
    • Kuller L.H., Tracy R., Belloso W., De Wit S., Drummond F., Lane H.C., et al. Inflammatory and coagulation biomarkers and mortality in patients with HIV infection. PLoS Medicine 2008, 5:e203.
    • (2008) PLoS Medicine , vol.5
    • Kuller, L.H.1    Tracy, R.2    Belloso, W.3    De Wit, S.4    Drummond, F.5    Lane, H.C.6
  • 37
    • 20844450412 scopus 로고    scopus 로고
    • Peripheral S-phase T cells in HIV disease have a central memory phenotype and rarely have evidence of recent T cell receptor engagement
    • Sieg S.F., Rodriguez B., Asaad R., Jiang W., Bazdar D.A., Lederman M.M. Peripheral S-phase T cells in HIV disease have a central memory phenotype and rarely have evidence of recent T cell receptor engagement. The Journal of Infectious Diseases 2005, 192:62-70.
    • (2005) The Journal of Infectious Diseases , vol.192 , pp. 62-70
    • Sieg, S.F.1    Rodriguez, B.2    Asaad, R.3    Jiang, W.4    Bazdar, D.A.5    Lederman, M.M.6
  • 39
    • 57449097558 scopus 로고    scopus 로고
    • Homeostasis of naive and memory T cells
    • Surh C.D., Sprent J. Homeostasis of naive and memory T cells. Immunity 2008, 29:848-862.
    • (2008) Immunity , vol.29 , pp. 848-862
    • Surh, C.D.1    Sprent, J.2
  • 41
    • 0035138982 scopus 로고    scopus 로고
    • Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis
    • Napolitano L.A., Grant R.M., Deeks S.G., Schmidt D., De Rosa S.C., Herzenberg L.A., et al. Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nature Medicine 2001, 7:73-79.
    • (2001) Nature Medicine , vol.7 , pp. 73-79
    • Napolitano, L.A.1    Grant, R.M.2    Deeks, S.G.3    Schmidt, D.4    De Rosa, S.C.5    Herzenberg, L.A.6
  • 43
    • 18944379196 scopus 로고    scopus 로고
    • The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance
    • Fry T.J., Mackall C.L. The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. Journal of Immunology 2005, 174:6571-6576.
    • (2005) Journal of Immunology , vol.174 , pp. 6571-6576
    • Fry, T.J.1    Mackall, C.L.2
  • 44
    • 18744435046 scopus 로고    scopus 로고
    • Restoration of T-cell homeostasis after T-cell depletion
    • Mackall C.L., Hakim F.T., Gress R.E. Restoration of T-cell homeostasis after T-cell depletion. Seminars in Immunology 1997, 9:339-346.
    • (1997) Seminars in Immunology , vol.9 , pp. 339-346
    • Mackall, C.L.1    Hakim, F.T.2    Gress, R.E.3
  • 45
    • 33847401590 scopus 로고    scopus 로고
    • Idiopathic CD4+ T lymphocytopenia is associated with increases in immature/transitional B cells and serum levels of IL-7
    • Malaspina A., Moir S., Chaitt D.G., Rehm C.A., Kottilil S., Falloon J., et al. Idiopathic CD4+ T lymphocytopenia is associated with increases in immature/transitional B cells and serum levels of IL-7. Blood 2007, 109:2086-2088.
    • (2007) Blood , vol.109 , pp. 2086-2088
    • Malaspina, A.1    Moir, S.2    Chaitt, D.G.3    Rehm, C.A.4    Kottilil, S.5    Falloon, J.6
  • 46
    • 0033831175 scopus 로고    scopus 로고
    • Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection
    • Hazenberg M.D., Otto S.A., Cohen Stuart J.W., Verschuren M.C., Borleffs J.C., Boucher C.A., et al. Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection. Nature Medicine 2000, 6:1036-1042.
    • (2000) Nature Medicine , vol.6 , pp. 1036-1042
    • Hazenberg, M.D.1    Otto, S.A.2    Cohen Stuart, J.W.3    Verschuren, M.C.4    Borleffs, J.C.5    Boucher, C.A.6
  • 47
    • 17144440358 scopus 로고    scopus 로고
    • Distinctions between CD8+ and CD4+ T-cell regenerative pathways result in prolonged T-cell subset imbalance after intensive chemotherapy
    • Mackall C.L., Fleisher T.A., Brown M.R., Andrich M.P., Chen C.C., Feuerstein I.M., et al. Distinctions between CD8+ and CD4+ T-cell regenerative pathways result in prolonged T-cell subset imbalance after intensive chemotherapy. Blood 1997, 89:3700-3707.
    • (1997) Blood , vol.89 , pp. 3700-3707
    • Mackall, C.L.1    Fleisher, T.A.2    Brown, M.R.3    Andrich, M.P.4    Chen, C.C.5    Feuerstein, I.M.6
  • 50
    • 79951825000 scopus 로고    scopus 로고
    • CD4 and CD8 T cell immune activation during chronic HIV infection: roles of homeostasis, HIV, Type I IFN, and IL-7
    • Catalfamo M., Wilhelm C., Tcheung L., Proschan M., Friesen T., Park J.H., et al. CD4 and CD8 T cell immune activation during chronic HIV infection: roles of homeostasis, HIV, Type I IFN, and IL-7. Journal of Immunology 2011, 186:2106-2116.
    • (2011) Journal of Immunology , vol.186 , pp. 2106-2116
    • Catalfamo, M.1    Wilhelm, C.2    Tcheung, L.3    Proschan, M.4    Friesen, T.5    Park, J.H.6
  • 51
    • 79960453203 scopus 로고    scopus 로고
    • Differential effects of HIV viral load and CD4 count on proliferation of naive and memory CD4 and CD8 T lymphocytes
    • Srinivasula S., Lempicki R.A., Adelsberger J.W., Huang C.Y., Roark J., Lee P.I., et al. Differential effects of HIV viral load and CD4 count on proliferation of naive and memory CD4 and CD8 T lymphocytes. Blood 2011, 118:262-270.
    • (2011) Blood , vol.118 , pp. 262-270
    • Srinivasula, S.1    Lempicki, R.A.2    Adelsberger, J.W.3    Huang, C.Y.4    Roark, J.5    Lee, P.I.6
  • 52
    • 84857416171 scopus 로고    scopus 로고
    • Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans
    • den Braber I., Mugwagwa T., Vrisekoop N., Westera L., Mogling R., Bregje de Boer A., et al. Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans. Immunity 2012, 36:288-297.
    • (2012) Immunity , vol.36 , pp. 288-297
    • den Braber, I.1    Mugwagwa, T.2    Vrisekoop, N.3    Westera, L.4    Mogling, R.5    Bregje de Boer, A.6
  • 54
    • 84861733896 scopus 로고    scopus 로고
    • Naive T cells are dispensable for memory CD4+ T cell homeostasis in progressive simian immunodeficiency virus infection
    • Okoye A.A., Rohankhedkar M., Abana C., Pattenn A., Reyes M., Pexton C., et al. Naive T cells are dispensable for memory CD4+ T cell homeostasis in progressive simian immunodeficiency virus infection. The Journal of Experimental Medicine 2012, 209:641-651.
    • (2012) The Journal of Experimental Medicine , vol.209 , pp. 641-651
    • Okoye, A.A.1    Rohankhedkar, M.2    Abana, C.3    Pattenn, A.4    Reyes, M.5    Pexton, C.6
  • 55
    • 33644822414 scopus 로고    scopus 로고
    • Pathogenesis of HIV infection: what the virus spares is as important as what it destroys
    • Grossman Z., Meier-Schellersheim M., Paul W.E., Picker L.J. Pathogenesis of HIV infection: what the virus spares is as important as what it destroys. Nature Medicine 2006, 12:289-295.
    • (2006) Nature Medicine , vol.12 , pp. 289-295
    • Grossman, Z.1    Meier-Schellersheim, M.2    Paul, W.E.3    Picker, L.J.4
  • 56
    • 67649876115 scopus 로고    scopus 로고
    • New insights into the regulation of T cells by gamma(c) family cytokines
    • Rochman Y., Spolski R., Leonard W.J. New insights into the regulation of T cells by gamma(c) family cytokines. Nature Reviews Immunology 2009, 9:480-490.
    • (2009) Nature Reviews Immunology , vol.9 , pp. 480-490
    • Rochman, Y.1    Spolski, R.2    Leonard, W.J.3
  • 57
    • 0036624721 scopus 로고    scopus 로고
    • Interleukin-7: from bench to clinic
    • Fry T.J., Mackall C.L. Interleukin-7: from bench to clinic. Blood 2002, 99:3892-3904.
    • (2002) Blood , vol.99 , pp. 3892-3904
    • Fry, T.J.1    Mackall, C.L.2
  • 59
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: new surprises in the Jak/Stat pathway
    • O'Shea J.J., Gadina M., Schreiber R.D. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 2002, 109(Suppl.):S121-S131.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • O'Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 60
    • 33846632842 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression: intelligent design
    • Mazzucchelli R., Durum S.K. Interleukin-7 receptor expression: intelligent design. Nature Reviews Immunology 2007, 7:144-154.
    • (2007) Nature Reviews Immunology , vol.7 , pp. 144-154
    • Mazzucchelli, R.1    Durum, S.K.2
  • 62
    • 84860418562 scopus 로고    scopus 로고
    • Expression of gamma-chain cytokine receptors on CD8(+) T cells in HIV infection with a focus on IL-7Ralpha (CD127)
    • Crawley A.M., Angel J.B. Expression of gamma-chain cytokine receptors on CD8(+) T cells in HIV infection with a focus on IL-7Ralpha (CD127). Immunology and Cell Biology 2012, 90:379-387.
    • (2012) Immunology and Cell Biology , vol.90 , pp. 379-387
    • Crawley, A.M.1    Angel, J.B.2
  • 63
    • 0038545516 scopus 로고    scopus 로고
    • Homeostasis of naive and memory CD4+ T cells: IL-2 and IL-7 differentially regulate the balance between proliferation and Fas-mediated apoptosis
    • Jaleco S., Swainson L., Dardalhon V., Burjanadze M., Kinet S., Taylor N. Homeostasis of naive and memory CD4+ T cells: IL-2 and IL-7 differentially regulate the balance between proliferation and Fas-mediated apoptosis. Journal of Immunology 2003, 171:61-68.
    • (2003) Journal of Immunology , vol.171 , pp. 61-68
    • Jaleco, S.1    Swainson, L.2    Dardalhon, V.3    Burjanadze, M.4    Kinet, S.5    Taylor, N.6
  • 64
    • 14644423251 scopus 로고    scopus 로고
    • Interleukin-7 signalling is sufficient to phenotypically and functionally prime human CD4 naive T cells
    • Managlia E.Z., Landay A., Al-Harthi L. Interleukin-7 signalling is sufficient to phenotypically and functionally prime human CD4 naive T cells. Immunology 2005, 114:322-335.
    • (2005) Immunology , vol.114 , pp. 322-335
    • Managlia, E.Z.1    Landay, A.2    Al-Harthi, L.3
  • 65
    • 34247156743 scopus 로고    scopus 로고
    • Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection
    • Fluur C., De Milito A., Fry T.J., Vivar N., Eidsmo L., Atlas A., et al. Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection. Journal of Immunology 2007, 178:5340-5350.
    • (2007) Journal of Immunology , vol.178 , pp. 5340-5350
    • Fluur, C.1    De Milito, A.2    Fry, T.J.3    Vivar, N.4    Eidsmo, L.5    Atlas, A.6
  • 66
    • 51649123313 scopus 로고    scopus 로고
    • Priming of T cells to Fas-mediated proliferative signals by interleukin-7
    • Rethi B., Vivar N., Sammicheli S., Fluur C., Ruffin N., Atlas A., et al. Priming of T cells to Fas-mediated proliferative signals by interleukin-7. Blood 2008, 112:1195-1204.
    • (2008) Blood , vol.112 , pp. 1195-1204
    • Rethi, B.1    Vivar, N.2    Sammicheli, S.3    Fluur, C.4    Ruffin, N.5    Atlas, A.6
  • 67
    • 72949100401 scopus 로고    scopus 로고
    • Naive T cell homeostasis: from awareness of space to a sense of place
    • Takada K., Jameson S.C. Naive T cell homeostasis: from awareness of space to a sense of place. Nature Reviews Immunology 2009, 9:823-832.
    • (2009) Nature Reviews Immunology , vol.9 , pp. 823-832
    • Takada, K.1    Jameson, S.C.2
  • 69
    • 33646689587 scopus 로고    scopus 로고
    • Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection
    • Schacker T.W., Brenchley J.M., Beilman G.J., Reilly C., Pambuccian S.E., Taylor J., et al. Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection. Clinical and Vaccine Immunology 2006, 13:556-560.
    • (2006) Clinical and Vaccine Immunology , vol.13 , pp. 556-560
    • Schacker, T.W.1    Brenchley, J.M.2    Beilman, G.J.3    Reilly, C.4    Pambuccian, S.E.5    Taylor, J.6
  • 70
    • 50949112602 scopus 로고    scopus 로고
    • Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection
    • van Grevenynghe J., Halwani R., Chomont N., Ancuta P., Peretz Y., Tanel A., et al. Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection. Seminars in Immunology 2008, 20:196-203.
    • (2008) Seminars in Immunology , vol.20 , pp. 196-203
    • van Grevenynghe, J.1    Halwani, R.2    Chomont, N.3    Ancuta, P.4    Peretz, Y.5    Tanel, A.6
  • 72
    • 40449085117 scopus 로고    scopus 로고
    • Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection
    • van Grevenynghe J., Procopio F.A., He Z., Chomont N., Riou C., Zhang Y., et al. Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection. Nature Medicine 2008, 14:266-274.
    • (2008) Nature Medicine , vol.14 , pp. 266-274
    • van Grevenynghe, J.1    Procopio, F.A.2    He, Z.3    Chomont, N.4    Riou, C.5    Zhang, Y.6
  • 73
    • 84857479601 scopus 로고    scopus 로고
    • Lymphoid tissue damage in HIV-1 infection depletes naive T cells and limits T cell reconstitution after antiretroviral therapy
    • Zeng M., Southern P.J., Reilly C.S., Beilman G.J., Chipman J.G., Schacker T.W., et al. Lymphoid tissue damage in HIV-1 infection depletes naive T cells and limits T cell reconstitution after antiretroviral therapy. PLoS Pathogens 2012, 8:e1002437.
    • (2012) PLoS Pathogens , vol.8
    • Zeng, M.1    Southern, P.J.2    Reilly, C.S.3    Beilman, G.J.4    Chipman, J.G.5    Schacker, T.W.6
  • 75
    • 0028912032 scopus 로고
    • Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study
    • Kovacs J.A., Baseler M., Dewar R.J., Vogel S., Davey R.T., Falloon J., et al. Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study. The New England Journal of Medicine 1995, 332:567-575.
    • (1995) The New England Journal of Medicine , vol.332 , pp. 567-575
    • Kovacs, J.A.1    Baseler, M.2    Dewar, R.J.3    Vogel, S.4    Davey, R.T.5    Falloon, J.6
  • 79
    • 67650590873 scopus 로고    scopus 로고
    • IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection
    • Sereti I., Dunham R.M., Spritzler J., Aga E., Proschan M.A., Medvik K., et al. IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection. Blood 2009, 113:6304-6314.
    • (2009) Blood , vol.113 , pp. 6304-6314
    • Sereti, I.1    Dunham, R.M.2    Spritzler, J.3    Aga, E.4    Proschan, M.A.5    Medvik, K.6
  • 80
    • 78650903022 scopus 로고    scopus 로고
    • HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy
    • Imamichi H., Degray G., Asmuth D.M., Fischl M.A., Landay A.L., Lederman M.M., et al. HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy. AIDS (London, England) 2011, 25:159-164.
    • (2011) AIDS (London, England) , vol.25 , pp. 159-164
    • Imamichi, H.1    Degray, G.2    Asmuth, D.M.3    Fischl, M.A.4    Landay, A.L.5    Lederman, M.M.6
  • 81
    • 40449100795 scopus 로고    scopus 로고
    • IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8+ T cell responses
    • Mueller Y.M., Do D.H., Altork S.R., Artlett C.M., Gracely E.J., Katsetos C.D., et al. IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8+ T cell responses. Journal of Immunology 2008, 180:350-360.
    • (2008) Journal of Immunology , vol.180 , pp. 350-360
    • Mueller, Y.M.1    Do, D.H.2    Altork, S.R.3    Artlett, C.M.4    Gracely, E.J.5    Katsetos, C.D.6
  • 83
    • 80052413595 scopus 로고    scopus 로고
    • IL-15 delays suppression and fails to promote immune reconstitution in virally suppressed chronically SIV-infected macaques
    • Lugli E., Mueller Y.M., Lewis M.G., Villinger F., Katsikis P.D., Roederer M. IL-15 delays suppression and fails to promote immune reconstitution in virally suppressed chronically SIV-infected macaques. Blood 2011, 118:2520-2529.
    • (2011) Blood , vol.118 , pp. 2520-2529
    • Lugli, E.1    Mueller, Y.M.2    Lewis, M.G.3    Villinger, F.4    Katsikis, P.D.5    Roederer, M.6
  • 84
    • 84255197274 scopus 로고    scopus 로고
    • IL-15 administered by continuous infusion to rhesus macaques induces massive expansion of CD8+ T effector memory population in peripheral blood
    • Sneller M.C., Kopp W.C., Engelke K.J., Yovandich J.L., Creekmore S.P., Waldmann T.A., et al. IL-15 administered by continuous infusion to rhesus macaques induces massive expansion of CD8+ T effector memory population in peripheral blood. Blood 2011, 118:6845-6848.
    • (2011) Blood , vol.118 , pp. 6845-6848
    • Sneller, M.C.1    Kopp, W.C.2    Engelke, K.J.3    Yovandich, J.L.4    Creekmore, S.P.5    Waldmann, T.A.6
  • 87
    • 34247170486 scopus 로고    scopus 로고
    • HIV-1 immunopathogenesis: how good interferon turns bad
    • Herbeuval J.P., Shearer G.M. HIV-1 immunopathogenesis: how good interferon turns bad. Clinical Immunology 2007, 123:121-128.
    • (2007) Clinical Immunology , vol.123 , pp. 121-128
    • Herbeuval, J.P.1    Shearer, G.M.2
  • 88
    • 34147115208 scopus 로고    scopus 로고
    • HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells
    • Boasso A., Herbeuval J.P., Hardy A.W., Anderson S.A., Dolan M.J., Fuchs D., et al. HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells. Blood 2007, 109:3351-3359.
    • (2007) Blood , vol.109 , pp. 3351-3359
    • Boasso, A.1    Herbeuval, J.P.2    Hardy, A.W.3    Anderson, S.A.4    Dolan, M.J.5    Fuchs, D.6
  • 89
    • 34247350014 scopus 로고    scopus 로고
    • How does indoleamine 2,3-dioxygenase contribute to HIV-mediated immune dysregulation
    • Boasso A., Shearer G.M. How does indoleamine 2,3-dioxygenase contribute to HIV-mediated immune dysregulation. Current Drug Metabolism 2007, 8:217-223.
    • (2007) Current Drug Metabolism , vol.8 , pp. 217-223
    • Boasso, A.1    Shearer, G.M.2
  • 90
    • 51849112883 scopus 로고    scopus 로고
    • HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation
    • Boasso A., Hardy A.W., Anderson S.A., Dolan M.J., Shearer G.M. HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation. PLoS One 2008, 3:e2961.
    • (2008) PLoS One , vol.3
    • Boasso, A.1    Hardy, A.W.2    Anderson, S.A.3    Dolan, M.J.4    Shearer, G.M.5
  • 91
    • 72849132344 scopus 로고    scopus 로고
    • Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys
    • Bosinger S.E., Li Q., Gordon S.N., Klatt N.R., Duan L., Xu L., et al. Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. The Journal of Clinical Investigation 2009, 119:3556-3572.
    • (2009) The Journal of Clinical Investigation , vol.119 , pp. 3556-3572
    • Bosinger, S.E.1    Li, Q.2    Gordon, S.N.3    Klatt, N.R.4    Duan, L.5    Xu, L.6
  • 92
    • 72849136282 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response
    • Jacquelin B., Mayau V., Targat B., Liovat A.S., Kunkel D., Petitjean G., et al. Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response. The Journal of Clinical Investigation 2009, 119:3544-3555.
    • (2009) The Journal of Clinical Investigation , vol.119 , pp. 3544-3555
    • Jacquelin, B.1    Mayau, V.2    Targat, B.3    Liovat, A.S.4    Kunkel, D.5    Petitjean, G.6
  • 93
    • 53549103852 scopus 로고    scopus 로고
    • Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections
    • Mandl J.N., Barry A.P., Vanderford T.H., Kozyr N., Chavan R., Klucking S., et al. Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Nature Medicine 2008, 14:1077-1087.
    • (2008) Nature Medicine , vol.14 , pp. 1077-1087
    • Mandl, J.N.1    Barry, A.P.2    Vanderford, T.H.3    Kozyr, N.4    Chavan, R.5    Klucking, S.6
  • 94
    • 38849134878 scopus 로고    scopus 로고
    • Chronic CD4+ T-cell activation and depletion in human immunodeficiency virus type 1 infection: type I interferon-mediated disruption of T-cell dynamics
    • Sedaghat A.R., German J., Teslovich T.M., Cofrancesco J., Jie C.C., Talbot C.C., et al. Chronic CD4+ T-cell activation and depletion in human immunodeficiency virus type 1 infection: type I interferon-mediated disruption of T-cell dynamics. Journal of Virology 2008, 82:1870-1883.
    • (2008) Journal of Virology , vol.82 , pp. 1870-1883
    • Sedaghat, A.R.1    German, J.2    Teslovich, T.M.3    Cofrancesco, J.4    Jie, C.C.5    Talbot, C.C.6
  • 95
    • 33947419675 scopus 로고    scopus 로고
    • Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T cells
    • Hyrcza M.D., Kovacs C., Loutfy M., Halpenny R., Heisler L., Yang S., et al. Distinct transcriptional profiles in ex vivo CD4+ and CD8+ T cells are established early in human immunodeficiency virus type 1 infection and are characterized by a chronic interferon response as well as extensive transcriptional changes in CD8+ T cells. Journal of Virology 2007, 81:3477-3486.
    • (2007) Journal of Virology , vol.81 , pp. 3477-3486
    • Hyrcza, M.D.1    Kovacs, C.2    Loutfy, M.3    Halpenny, R.4    Heisler, L.5    Yang, S.6
  • 96
    • 1442349729 scopus 로고    scopus 로고
    • Functional genomic analysis of the response of HIV-1-infected lymphatic tissue to antiretroviral therapy
    • Li Q., Schacker T., Carlis J., Beilman G., Nguyen P., Haase A.T. Functional genomic analysis of the response of HIV-1-infected lymphatic tissue to antiretroviral therapy. The Journal of Infectious Diseases 2004, 189:572-582.
    • (2004) The Journal of Infectious Diseases , vol.189 , pp. 572-582
    • Li, Q.1    Schacker, T.2    Carlis, J.3    Beilman, G.4    Nguyen, P.5    Haase, A.T.6
  • 97
    • 79957912712 scopus 로고    scopus 로고
    • Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque
    • Rotger M., Dalmau J., Rauch A., McLaren P., Bosinger S.E., Martinez R., et al. Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque. The Journal of Clinical Investigation 2011, 121:2391-2400.
    • (2011) The Journal of Clinical Investigation , vol.121 , pp. 2391-2400
    • Rotger, M.1    Dalmau, J.2    Rauch, A.3    McLaren, P.4    Bosinger, S.E.5    Martinez, R.6
  • 99
    • 33645790477 scopus 로고    scopus 로고
    • Gene expression profiles in hepatitis C virus (HCV) and HIV coinfection: class prediction analyses before treatment predict the outcome of anti-HCV therapy among HIV-coinfected persons
    • Lempicki R.A., Polis M.A., Yang J., McLaughlin M., Koratich C., Huang D.W., et al. Gene expression profiles in hepatitis C virus (HCV) and HIV coinfection: class prediction analyses before treatment predict the outcome of anti-HCV therapy among HIV-coinfected persons. The Journal of Infectious Diseases 2006, 193:1172-1177.
    • (2006) The Journal of Infectious Diseases , vol.193 , pp. 1172-1177
    • Lempicki, R.A.1    Polis, M.A.2    Yang, J.3    McLaughlin, M.4    Koratich, C.5    Huang, D.W.6
  • 100
    • 81855218589 scopus 로고    scopus 로고
    • HIV reservoirs and the possibility of a cure for HIV infection
    • Palmer S., Josefsson L., Coffin J.M. HIV reservoirs and the possibility of a cure for HIV infection. Journal of Internal Medicine 2011, 270:550-560.
    • (2011) Journal of Internal Medicine , vol.270 , pp. 550-560
    • Palmer, S.1    Josefsson, L.2    Coffin, J.M.3
  • 101
    • 77950537810 scopus 로고    scopus 로고
    • HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects
    • Buzon M.J., Massanella M., Llibre J.M., Esteve A., Dahl V., Puertas M.C., et al. HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects. Nature Medicine 2010, 16:460-465.
    • (2010) Nature Medicine , vol.16 , pp. 460-465
    • Buzon, M.J.1    Massanella, M.2    Llibre, J.M.3    Esteve, A.4    Dahl, V.5    Puertas, M.C.6
  • 103
    • 0028877891 scopus 로고
    • Reverse transcriptase sequence of paired isolates of cerebrospinal fluid and blood from patients infected with human immunodeficiency virus type 1 during zidovudine treatment
    • Di Stefano M., Sabri F., Leitner T., Svennerholm B., Hagberg L., Norkrans G., et al. Reverse transcriptase sequence of paired isolates of cerebrospinal fluid and blood from patients infected with human immunodeficiency virus type 1 during zidovudine treatment. Journal of Clinical Microbiology 1995, 33:352-355.
    • (1995) Journal of Clinical Microbiology , vol.33 , pp. 352-355
    • Di Stefano, M.1    Sabri, F.2    Leitner, T.3    Svennerholm, B.4    Hagberg, L.5    Norkrans, G.6
  • 104
    • 0031984787 scopus 로고    scopus 로고
    • Analysis of the temporal relationship between human immunodeficiency virus type 1 quasispecies in sequential blood samples and various organs obtained at autopsy
    • van't Wout A.B., Ran L.J., Kuiken C.L., Kootstra N.A., Pals S.T., Schuitemaker H. Analysis of the temporal relationship between human immunodeficiency virus type 1 quasispecies in sequential blood samples and various organs obtained at autopsy. Journal of Virology 1998, 72:488-496.
    • (1998) Journal of Virology , vol.72 , pp. 488-496
    • van't Wout, A.B.1    Ran, L.J.2    Kuiken, C.L.3    Kootstra, N.A.4    Pals, S.T.5    Schuitemaker, H.6
  • 106
    • 78650682935 scopus 로고    scopus 로고
    • Changes in inflammatory and coagulation biomarkers: a randomized comparison of immediate versus deferred antiretroviral therapy in patients with HIV infection
    • Baker J.V., Neuhaus J., Duprez D., Kuller L.H., Tracy R., Belloso W.H., et al. Changes in inflammatory and coagulation biomarkers: a randomized comparison of immediate versus deferred antiretroviral therapy in patients with HIV infection. Journal of Acquired Immune Deficiency 2010, 56:36-43.
    • (2010) Journal of Acquired Immune Deficiency , vol.56 , pp. 36-43
    • Baker, J.V.1    Neuhaus, J.2    Duprez, D.3    Kuller, L.H.4    Tracy, R.5    Belloso, W.H.6


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