-
1
-
-
58849097959
-
Making a commitment: Cell lineage allocation and axis patterning in the early mouse embryo
-
Arnold SJ, Robertson EJ (2009) Making a commitment: Cell lineage allocation and axis patterning in the early mouse embryo. Nat Rev Mol Cell Biol 10:91-103
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 91-103
-
-
Arnold, S.J.1
Robertson, E.J.2
-
2
-
-
79956306617
-
Regulation of X-chromosome inactivation by the X-inactivation centre
-
Augui S, Nora EP, Heard E (2011) Regulation of X-chromosome inactivation by the X-inactivation centre. Nat Rev 12:429-442
-
(2011)
Nat Rev
, vol.12
, pp. 429-442
-
-
Augui, S.1
Nora, E.P.2
Heard, E.3
-
3
-
-
78751590899
-
Silencing chromatin: Comparing modes and mechanisms
-
Beisel C, Paro R (2011) Silencing chromatin: Comparing modes and mechanisms. Nat Rev 12:123-135
-
(2011)
Nat Rev
, vol.12
, pp. 123-135
-
-
Beisel, C.1
Paro, R.2
-
4
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16:6-21
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
5
-
-
79955600698
-
The liberation of embryonic stem cells
-
Blair K, Wray J, Smith A (2011) The liberation of embryonic stem cells. PLoS Genet 7:e1002019
-
(2011)
PLoS Genet
, vol.7
-
-
Blair, K.1
Wray, J.2
Smith, A.3
-
6
-
-
42649100978
-
SmcHD1, containing a structuralmaintenance- of-chromosomes hinge domain, has a critical role in X inactivation
-
Blewitt ME, Gendrel AV, Pang Z, Sparrow DB, Whitelaw N, Craig JM, Apedaile A, Hilton DJ, Dunwoodie SL, Brockdorff N, Kay GF, Whitelaw E (2008) SmcHD1, containing a structuralmaintenance- of-chromosomes hinge domain, has a critical role in X inactivation. Nat Genet 40:663-669
-
(2008)
Nat Genet
, vol.40
, pp. 663-669
-
-
Blewitt, M.E.1
Gendrel, A.V.2
Pang, Z.3
Sparrow, D.B.4
Whitelaw, N.5
Craig, J.M.6
Apedaile, A.7
Hilton, D.J.8
Dunwoodie, S.L.9
Brockdorff, N.10
Kay, G.F.11
Whitelaw, E.12
-
7
-
-
34648833002
-
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
-
Bostick M, Kim JK, Esteve PO, Clark A, Pradhan S, Jacobsen SE (2007) UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science (New York, NY) 317:1760-1764
-
(2007)
Science (New York, NY
, vol.317
, pp. 1760-1764
-
-
Bostick, M.1
Kim, J.K.2
Esteve, P.O.3
Clark, A.4
Pradhan, S.5
Jacobsen, S.E.6
-
8
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, Jaenisch R (2006) Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441:349-353
-
(2006)
Nature
, vol.441
, pp. 349-353
-
-
Boyer, L.A.1
Plath, K.2
Zeitlinger, J.3
Brambrink, T.4
Medeiros, L.A.5
Lee, T.I.6
Levine, S.S.7
Wernig, M.8
Tajonar, A.9
Ray, M.K.10
Bell, G.W.11
Otte, A.P.12
Vidal, M.13
Gifford, D.K.14
Young, R.A.15
Jaenisch, R.16
-
9
-
-
33646870495
-
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
-
Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K (2006) Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 20:1123-1136
-
(2006)
Genes Dev
, vol.20
, pp. 1123-1136
-
-
Bracken, A.P.1
Dietrich, N.2
Pasini, D.3
Hansen, K.H.4
Helin, K.5
-
10
-
-
34447527158
-
Derivation of pluripotent epiblast stem cells from mammalian embryos
-
Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P, Sun B, de Sousa C, Lopes SM, Howlett SK, Clarkson A, Ahrlund-Richter L, Pedersen RA, Vallier L (2007) Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448:191-195
-
(2007)
Nature
, vol.448
, pp. 191-195
-
-
Brons, I.G.1
Smithers, L.E.2
Trotter, M.W.3
Rugg-Gunn, P.4
Sun, B.5
De Sousa, C.6
Lopes, S.M.7
Howlett, S.K.8
Clarkson, A.9
Ahrlund-Richter, L.10
Pedersen, R.A.11
Vallier, L.12
-
11
-
-
48649091905
-
Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency
-
Chamberlain SJ, Yee D, Magnuson T (2008) Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency. Stem cells (Dayton, Ohio) 26:1496-1505
-
(2008)
Stem cells (Dayton, Ohio
, vol.26
, pp. 1496-1505
-
-
Chamberlain, S.J.1
Yee, D.2
Magnuson, T.3
-
12
-
-
33646527782
-
Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway
-
Chazaud C, Yamanaka Y, Pawson T, Rossant J (2006) Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell 10:615-624
-
(2006)
Dev Cell
, vol.10
, pp. 615-624
-
-
Chazaud, C.1
Yamanaka, Y.2
Pawson, T.3
Rossant, J.4
-
13
-
-
0035858882
-
Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation
-
Csankovszki G, Nagy A, Jaenisch R (2001) Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. J Cell Biol 153:773-784
-
(2001)
J Cell Biol
, vol.153
, pp. 773-784
-
-
Csankovszki, G.1
Nagy, A.2
Jaenisch, R.3
-
14
-
-
79961139741
-
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
-
Dawlaty MM, Ganz K, Powell BE, Hu YC, Markoulaki S, Cheng AW, Gao Q, Kim J, Choi SW, Page DC, Jaenisch R (2011) Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell 9:166-175
-
(2011)
Cell Stem Cell
, vol.9
, pp. 166-175
-
-
Dawlaty, M.M.1
Ganz, K.2
Powell, B.E.3
Hu, Y.C.4
Markoulaki, S.5
Cheng, A.W.6
Gao, Q.7
Kim, J.8
Choi, S.W.9
Page, D.C.10
Jaenisch, R.11
-
15
-
-
7744228427
-
Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation
-
de Napoles M, Mermoud JE, Wakao R, Tang YA, Endoh M, Appanah R, Nesterova TB, Silva J, Otte AP, Vidal M, Koseki H, Brockdorff N (2004) Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev Cell 7:663-676
-
(2004)
Dev Cell
, vol.7
, pp. 663-676
-
-
De Napoles, M.1
Mermoud, J.E.2
Wakao, R.3
Tang, Y.A.4
Endoh, M.5
Appanah, R.6
Nesterova, T.B.7
Silva, J.8
Otte, A.P.9
Vidal, M.10
Koseki, H.11
Brockdorff, N.12
-
16
-
-
1542314243
-
Histone H3-K9 methyltransferase ESET is essential for early development
-
Dodge JE, Kang YK, Beppu H, Lei H, Li E (2004) Histone H3-K9 methyltransferase ESET is essential for early development. Mol Cell Biol 24:2478-2486
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2478-2486
-
-
Dodge, J.E.1
Kang, Y.K.2
Beppu, H.3
Lei, H.4
Li, E.5
-
17
-
-
82755182211
-
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells
-
Elling U, Taubenschmid J, Wirnsberger G, O'Malley R, Demers SP, Vanhaelen Q, Shukalyuk AI, Schmauss G, Schramek D, Schnuetgen F, von Melchner H, Ecker JR, Stanford WL, Zuber J, Stark A, Penninger JM(2011) Forward and reverse genetics through derivation of haploid mouse embryonic stem cells. Cell Stem Cell 9:563-574
-
(2011)
Cell Stem Cell
, vol.9
, pp. 563-574
-
-
Elling, U.1
Taubenschmid, J.2
Wirnsberger, G.3
O'Malley, R.4
Demers, S.P.5
Vanhaelen, Q.6
Shukalyuk, A.I.7
Schmauss, G.8
Schramek, D.9
Schnuetgen, F.10
Von Melchner, H.11
Ecker, J.R.12
Stanford, W.L.13
Zuber, J.14
Stark, A.15
Penninger, J.M.16
-
18
-
-
0042310137
-
Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development
-
Erhardt S, Su IH, Schneider R, Barton S, Bannister AJ, Perez-Burgos L, Jenuwein T, Kouzarides T, Tarakhovsky A, Surani MA (2003) Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development 130:4235-4248
-
(2003)
Development
, vol.130
, pp. 4235-4248
-
-
Erhardt, S.1
Su, I.H.2
Schneider, R.3
Barton, S.4
Bannister, A.J.5
Perez-Burgos, L.6
Jenuwein, T.7
Kouzarides, T.8
Tarakhovsky, A.9
Surani, M.A.10
-
19
-
-
77951947926
-
Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination
-
Eskeland R, Leeb M, Grimes GR, Kress C, Boyle S, Sproul D, Gilbert N, Fan Y, Skoultchi AI, Wutz A, Bickmore WA (2010) Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell 38:452-464
-
(2010)
Mol Cell
, vol.38
, pp. 452-464
-
-
Eskeland, R.1
Leeb, M.2
Grimes, G.R.3
Kress, C.4
Boyle, S.5
Sproul, D.6
Gilbert, N.7
Fan, Y.8
Skoultchi, A.I.9
Wutz, A.10
Bickmore, W.A.11
-
20
-
-
79960530899
-
Genomic imprinting: The emergence of an epigenetic paradigm
-
Ferguson-Smith AC (2011) Genomic imprinting: The emergence of an epigenetic paradigm. Nat Rev 12:565-575
-
(2011)
Nat Rev
, vol.12
, pp. 565-575
-
-
Ferguson-Smith, A.C.1
-
21
-
-
79956323623
-
Dynamic regulation of 5- hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G, Branco MR, Seisenberger S, Santos F, Krueger F, Hore TA, Marques CJ, Andrews S, ReikW(2011) Dynamic regulation of 5- hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473:398-402
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
Santos, F.4
Krueger, F.5
Hore, T.A.6
Marques, C.J.7
Andrews, S.8
Reik, W.9
-
23
-
-
0033988813
-
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
-
Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T (2000) DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat Genet 24:88-91
-
(2000)
Nat Genet
, vol.24
, pp. 88-91
-
-
Fuks, F.1
Burgers, W.A.2
Brehm, A.3
Hughes-Davies, L.4
Kouzarides, T.5
-
24
-
-
77956919550
-
Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation
-
Gehani SS, Agrawal-Singh S, Dietrich N, Christophersen NS, Helin K, Hansen K (2010) Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation. Mol Cell 39:886-900
-
(2010)
Mol Cell
, vol.39
, pp. 886-900
-
-
Gehani, S.S.1
Agrawal-Singh, S.2
Dietrich, N.3
Christophersen, N.S.4
Helin, K.5
Hansen, K.6
-
25
-
-
71449125977
-
Forcing cells to change lineages
-
Graf T, Enver T (2009) Forcing cells to change lineages. Nature 462:587-594
-
(2009)
Nature
, vol.462
, pp. 587-594
-
-
Graf, T.1
Enver, T.2
-
26
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
doi:10.1038/nature10443
-
Gu TP, Guo F, Yang H, Wu HP, Xu GF, Liu W, Xie ZG, Shi L, He X, Jin SG, Iqbal K, Shi YG, Deng Z, Szabo PE, Pfeifer GP, Li J, Xu GL (2011) The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 477:606-610. doi:10.1038/nature10443
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
Wu, H.P.4
Xu, G.F.5
Liu, W.6
Xie, Z.G.7
Shi, L.8
He, X.9
Jin, S.G.10
Iqbal, K.11
Shi, Y.G.12
Deng, Z.13
Szabo, P.E.14
Pfeifer, G.P.15
Li, J.16
Xu, G.L.17
-
27
-
-
66049136895
-
Klf4 reverts developmentally programmed restriction of ground state pluripotency
-
Guo G, Yang J, Nichols J, Hall JS, Eyres I, Mansfield W, Smith A (2009) Klf4 reverts developmentally programmed restriction of ground state pluripotency. Development 136:1063-1069
-
(2009)
Development
, vol.136
, pp. 1063-1069
-
-
Guo, G.1
Yang, J.2
Nichols, J.3
Hall, J.S.4
Eyres, I.5
Mansfield, W.6
Smith, A.7
-
28
-
-
80052869283
-
LincRNAs act in the circuitry controlling pluripotency and differentiation
-
Guttman M, Donaghey J, Carey BW, Garber M, Grenier JK, Munson G, Young G, Lucas AB, Ach R, Bruhn L, Yang X, Amit I, Meissner A, Regev A, Rinn JL, Root DE, Lander ES (2011) lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature 477:295-300
-
(2011)
Nature
, vol.477
, pp. 295-300
-
-
Guttman, M.1
Donaghey, J.2
Carey, B.W.3
Garber, M.4
Grenier, J.K.5
Munson, G.6
Young, G.7
Lucas, A.B.8
Ach, R.9
Bruhn, L.10
Yang, X.11
Amit, I.12
Meissner, A.13
Regev, A.14
Rinn, J.L.15
Root, D.E.16
Lander, E.S.17
-
29
-
-
0347763875
-
Dynamics of global gene expression changes during mouse preimplantation development
-
Hamatani T, Carter MG, Sharov AA, Ko MS (2004) Dynamics of global gene expression changes during mouse preimplantation development. Dev Cell 6:117-131
-
(2004)
Dev Cell
, vol.6
, pp. 117-131
-
-
Hamatani, T.1
Carter, M.G.2
Sharov, A.A.3
Ko, M.S.4
-
30
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He YF, Li BZ, Li Z, Liu P, Wang Y, Tang Q, Ding J, Jia Y, Chen Z, Li L, Sun Y, Li X, Dai Q, Song CX, Zhang K, He C, Xu GL (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science (New York, NY) 333:1303-1307
-
(2011)
Science (New York, NY
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
Ding, J.7
Jia, Y.8
Chen, Z.9
Li, L.10
Sun, Y.11
Li, X.12
Dai, Q.13
Song, C.X.14
Zhang, K.15
He, C.16
Xu, G.L.17
-
31
-
-
68049097008
-
Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington's canal
-
Hemberger M, Dean W, Reik W (2009) Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington's canal. Nat Rev Mol Cell Biol 10:526-537
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 526-537
-
-
Hemberger, M.1
Dean, W.2
Reik, W.3
-
32
-
-
77951871731
-
The JARID2-PRC2 duality
-
Herz HM, Shilatifard A (2010) The JARID2-PRC2 duality. Genes Dev 24:857-861
-
(2010)
Genes Dev
, vol.24
, pp. 857-861
-
-
Herz, H.M.1
Shilatifard, A.2
-
33
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
-
Iqbal K, Jin SG, Pfeifer GP, Szabo PE (2011) Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc Natl Acad Sci USA 108: 3642-3647
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabo, P.E.4
-
34
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y (2010) Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466:1129-1133
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
35
-
-
33644764030
-
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells
-
Kaji K, Caballero IM, MacLeod R, Nichols J, Wilson VA, Hendrich B (2006) The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol 8:285-292
-
(2006)
Nat Cell Biol
, vol.8
, pp. 285-292
-
-
Kaji, K.1
Caballero, I.M.2
MacLeod, R.3
Nichols, J.4
Wilson, V.A.5
Hendrich, B.6
-
36
-
-
34247333474
-
Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells
-
Kaji K, Nichols J, Hendrich B (2007) Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development 134:1123-1132
-
(2007)
Development
, vol.134
, pp. 1123-1132
-
-
Kaji, K.1
Nichols, J.2
Hendrich, B.3
-
37
-
-
19344375746
-
A chromosomal memory triggered by Xist regulates histone methylation in X inactivation
-
Kohlmaier A, Savarese F, Lachner M, Martens J, Jenuwein T, Wutz A (2004) A chromosomal memory triggered by Xist regulates histone methylation in X inactivation. PLoS Biol 2: E171
-
(2004)
PLoS Biol
, vol.2
-
-
Kohlmaier, A.1
Savarese, F.2
Lachner, M.3
Martens, J.4
Jenuwein, T.5
Wutz, A.6
-
38
-
-
55449105221
-
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains
-
Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, Presser A, Nusbaum C, Xie X, Chi AS, Adli M, Kasif S, Ptaszek LM, Cowan CA, Lander ES, Koseki H, Bernstein BE (2008) Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet 4: E1000242
-
(2008)
PLoS Genet
, vol.4
-
-
Ku, M.1
Koche, R.P.2
Rheinbay, E.3
Mendenhall, E.M.4
Endoh, M.5
Mikkelsen, T.S.6
Presser, A.7
Nusbaum, C.8
Xie, X.9
Chi, A.S.10
Adli, M.11
Kasif, S.12
Ptaszek, L.M.13
Cowan, C.A.14
Lander, E.S.15
Koseki, H.16
Bernstein, B.E.17
-
39
-
-
20244381688
-
Imprinted Xinactivation in extra-embryonic endoderm cell lines from mouse blastocysts
-
Kunath T, Arnaud D, Uy GD, Okamoto I, Chureau C, Yamanaka Y, Heard E, Gardner RL, Avner P, Rossant J (2005) Imprinted Xinactivation in extra-embryonic endoderm cell lines from mouse blastocysts. Development 132:1649-1661
-
(2005)
Development
, vol.132
, pp. 1649-1661
-
-
Kunath, T.1
Arnaud, D.2
Uy, G.D.3
Okamoto, I.4
Chureau, C.5
Yamanaka, Y.6
Heard, E.7
Gardner, R.L.8
Avner, P.9
Rossant, J.10
-
40
-
-
77953120646
-
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators
-
Landeira D, Sauer S, Poot R, Dvorkina M, Mazzarella L, Jorgensen HF, Pereira CF, Leleu M, Piccolo FM, Spivakov M, Brookes E, Pombo A, Fisher C, SkarnesWC, Snoek T, Bezstarosti K, Demmers J, Klose RJ, Casanova M, Tavares L, Brockdorff N, Merkenschlager M, Fisher AG (2010) Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. Nat Cell Biol 12:618-624
-
(2010)
Nat Cell Biol
, vol.12
, pp. 618-624
-
-
Landeira, D.1
Sauer, S.2
Poot, R.3
Dvorkina, M.4
Mazzarella, L.5
Jorgensen, H.F.6
Pereira, C.F.7
Leleu, M.8
Piccolo, F.M.9
Spivakov, M.10
Brookes, E.11
Pombo, A.12
Fisher, C.13
Skarnes, W.C.14
Snoek, T.15
Bezstarosti, K.16
Demmers, J.17
Klose, R.J.18
Casanova, M.19
Tavares, L.20
Brockdorff, N.21
Merkenschlager, M.22
Fisher, A.G.23
more..
-
41
-
-
34447508437
-
Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells
-
Leeb M, Wutz A (2007) Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells. J Cell Biol 178:219-229
-
(2007)
J Cell Biol
, vol.178
, pp. 219-229
-
-
Leeb, M.1
Wutz, A.2
-
42
-
-
80455174608
-
Derivation of haploid embryonic stem cells from mouse embryos
-
doi:10.1038/ nature10448
-
Leeb M, Wutz A (2011) Derivation of haploid embryonic stem cells from mouse embryos. Nature 479:131-134. doi:10.1038/ nature10448
-
(2011)
Nature
, vol.479
, pp. 131-134
-
-
Leeb, M.1
Wutz, A.2
-
43
-
-
76149142791
-
Polycomb complexes act redundantly to repress genomic repeats and genes
-
Leeb M, Pasini D, Novatchkova M, Jaritz M, Helin K, Wutz A (2010) Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev 24:265-276
-
(2010)
Genes Dev
, vol.24
, pp. 265-276
-
-
Leeb, M.1
Pasini, D.2
Novatchkova, M.3
Jaritz, M.4
Helin, K.5
Wutz, A.6
-
44
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69: 915-926
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
45
-
-
0027378582
-
Role for DNA methylation in genomic imprinting
-
Li E, Beard C, Jaenisch R (1993) Role for DNA methylation in genomic imprinting. Nature 366:362-365
-
(1993)
Nature
, vol.366
, pp. 362-365
-
-
Li, E.1
Beard, C.2
Jaenisch, R.3
-
46
-
-
76749083433
-
Jarid2 and PRC2, partners in regulating gene expression
-
Li G, Margueron R, Ku M, Chambon P, Bernstein BE, Reinberg D (2010) Jarid2 and PRC2, partners in regulating gene expression. Genes Dev 24:368-380
-
(2010)
Genes Dev
, vol.24
, pp. 368-380
-
-
Li, G.1
Margueron, R.2
Ku, M.3
Chambon, P.4
Bernstein, B.E.5
Reinberg, D.6
-
47
-
-
80054994283
-
Identification of genetic elements that autonomously determine DNA methylation states
-
Lienert F, Wirbelauer C, Som I, Dean A, Mohn F, Schubeler D (2011) Identification of genetic elements that autonomously determine DNA methylation states. Nat Genet 43:1091-1097
-
(2011)
Nat Genet
, vol.43
, pp. 1091-1097
-
-
Lienert, F.1
Wirbelauer, C.2
Som, I.3
Dean, A.4
Mohn, F.5
Schubeler, D.6
-
48
-
-
77149138834
-
KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation
-
Lohmann F, Loureiro J, Su H, Fang Q, Lei H, Lewis T, Yang Y, Labow M, Li E, Chen T, Kadam S (2010) KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation. Stem Cells (Dayton, Ohio) 28:201-212
-
(2010)
Stem Cells (Dayton, Ohio
, vol.28
, pp. 201-212
-
-
Lohmann, F.1
Loureiro, J.2
Su, H.3
Fang, Q.4
Lei, H.5
Lewis, T.6
Yang, Y.7
Labow, M.8
Li, E.9
Chen, T.10
Kadam, S.11
-
49
-
-
77956282774
-
Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells
-
Majewski IJ, Ritchie ME, Phipson B, Corbin J, Pakusch M, Ebert A, Busslinger M, Koseki H, Hu Y, Smyth GK, Alexander WS, Hilton DJ, Blewitt ME (2010) Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells. Blood 116:731-739
-
(2010)
Blood
, vol.116
, pp. 731-739
-
-
Majewski, I.J.1
Ritchie, M.E.2
Phipson, B.3
Corbin, J.4
Pakusch, M.5
Ebert, A.6
Busslinger, M.7
Koseki, H.8
Hu, Y.9
Smyth, G.K.10
Alexander, W.S.11
Hilton, D.J.12
Blewitt, M.E.13
-
50
-
-
0037172659
-
Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells
-
Mak W, Baxter J, Silva J, Newall AE, Otte AP, Brockdorff N (2002) Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells. Curr Biol 12:1016-1020
-
(2002)
Curr Biol
, vol.12
, pp. 1016-1020
-
-
Mak, W.1
Baxter, J.2
Silva, J.3
Newall, A.E.4
Otte, A.P.5
Brockdorff, N.6
-
51
-
-
0031044166
-
Xist-deficient mice are defective in dosage compensation but not spermatogenesis
-
Marahrens Y, Panning B, Dausman J, Strauss W, Jaenisch R (1997) Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev 11:156-166
-
(1997)
Genes Dev
, vol.11
, pp. 156-166
-
-
Marahrens, Y.1
Panning, B.2
Dausman, J.3
Strauss, W.4
Jaenisch, R.5
-
52
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES (2008) Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454:766-770
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
Wernig, M.4
Hanna, J.5
Sivachenko, A.6
Zhang, X.7
Bernstein, B.E.8
Nusbaum, C.9
Jaffe, D.B.10
Gnirke, A.11
Jaenisch, R.12
Lander, E.S.13
-
53
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineagecommitted cells
-
Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim TK, Koche RP, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, Xie X, Meissner A, Wernig M, Jaenisch R, Nusbaum C, Lander ES, Bernstein BE (2007) Genome-wide maps of chromatin state in pluripotent and lineagecommitted cells. Nature 448:553-560
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
Issac, B.4
Lieberman, E.5
Giannoukos, G.6
Alvarez, P.7
Brockman, W.8
Kim, T.K.9
Koche, R.P.10
Lee, W.11
Mendenhall, E.12
O'Donovan, A.13
Presser, A.14
Russ, C.15
Xie, X.16
Meissner, A.17
Wernig, M.18
Jaenisch, R.19
Nusbaum, C.20
Lander, E.S.21
Bernstein, B.E.22
more..
-
54
-
-
51649129596
-
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
-
Mohn F,Weber M, Rebhan M, Roloff TC, Richter J, Stadler MB, Bibel M, Schubeler D (2008) Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell 30:755-766
-
(2008)
Mol Cell
, vol.30
, pp. 755-766
-
-
Mohn, F.1
Weber, M.2
Rebhan, M.3
Roloff, T.C.4
Richter, J.5
Stadler, M.B.6
Bibel, M.7
Schubeler, D.8
-
55
-
-
80052476744
-
Molecular biology. Demystifying DNA demethylation
-
Nabel CS, Kohli RM (2011) Molecular biology. Demystifying DNA demethylation. Science (New York, NY) 333:1229-1230
-
(2011)
Science (New York, NY
, vol.333
, pp. 1229-1230
-
-
Nabel, C.S.1
Kohli, R.M.2
-
56
-
-
0025245614
-
Embryonic stem cells alone are able to support fetal development in the mouse
-
Nagy A, Gocza E, Diaz EM, Prideaux VR, Ivanyi E, Markkula M, Rossant J (1990) Embryonic stem cells alone are able to support fetal development in the mouse. Development 110:815-821
-
(1990)
Development
, vol.110
, pp. 815-821
-
-
Nagy, A.1
Gocza, E.2
Diaz, E.M.3
Prideaux, V.R.4
Ivanyi, E.5
Markkula, M.6
Rossant, J.7
-
57
-
-
55549119925
-
Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5
-
Ng RK, Dean W, Dawson C, Lucifero D, Madeja Z, Reik W, Hemberger M (2008) Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat Cell Biol 10:1280-1290
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1280-1290
-
-
Ng, R.K.1
Dean, W.2
Dawson, C.3
Lucifero, D.4
Madeja, Z.5
Reik, W.6
Hemberger, M.7
-
58
-
-
70349934958
-
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
-
Nichols J, Silva J, Roode M, Smith A (2009) Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development 136:3215-3222
-
(2009)
Development
, vol.136
, pp. 3215-3222
-
-
Nichols, J.1
Silva, J.2
Roode, M.3
Smith, A.4
-
59
-
-
28344436489
-
Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation
-
Niwa H, Toyooka Y, Shimosato D, Strumpf D, Takahashi K, Yagi R, Rossant J (2005) Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell 123:917-929
-
(2005)
Cell
, vol.123
, pp. 917-929
-
-
Niwa, H.1
Toyooka, Y.2
Shimosato, D.3
Strumpf, D.4
Takahashi, K.5
Yagi, R.6
Rossant, J.7
-
60
-
-
0034977239
-
The polycomb-group gene Ezh2 is required for early mouse development
-
O'Carroll D, Erhardt S, Pagani M, Barton SC, Surani MA, Jenuwein T (2001) The polycomb-group gene Ezh2 is required for early mouse development. Mol Cell Biol 21:4330-4336
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4330-4336
-
-
O'Carroll, D.1
Erhardt, S.2
Pagani, M.3
Barton, S.C.4
Surani, M.A.5
Jenuwein, T.6
-
61
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99:247-257
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
62
-
-
79958252915
-
Chromatin connections to pluripotency and cellular reprogramming
-
Orkin SH, Hochedlinger K (2011) Chromatin connections to pluripotency and cellular reprogramming. Cell 145:835-850
-
(2011)
Cell
, vol.145
, pp. 835-850
-
-
Orkin, S.H.1
Hochedlinger, K.2
-
63
-
-
77949414371
-
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells
-
Pasini D, Cloos PA, Walfridsson J, Olsson L, Bukowski JP, Johansen JV, Bak M, Tommerup N, Rappsilber J, Helin K (2010) JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells. Nature 464:306-310
-
(2010)
Nature
, vol.464
, pp. 306-310
-
-
Pasini, D.1
Cloos, P.A.2
Walfridsson, J.3
Olsson, L.4
Bukowski, J.P.5
Johansen, J.V.6
Bak, M.7
Tommerup, N.8
Rappsilber, J.9
Helin, K.10
-
64
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R, Ko M, McLoughlin EM, Brudno Y, Mahapatra S, Kapranov P, Tahiliani M, Daley GQ, Liu XS, Ecker JR, Milos PM, Agarwal S, Rao A (2011) Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 473:394-397
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
Henderson, H.R.4
Lister, R.5
Ko, M.6
McLoughlin, E.M.7
Brudno, Y.8
Mahapatra, S.9
Kapranov, P.10
Tahiliani, M.11
Daley, G.Q.12
Liu, X.S.13
Ecker, J.R.14
Milos, P.M.15
Agarwal, S.16
Rao, A.17
-
65
-
-
79956318370
-
De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state
-
Pawlak M, Jaenisch R (2011) De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. Genes Dev 25:1035-1040
-
(2011)
Genes Dev
, vol.25
, pp. 1035-1040
-
-
Pawlak, M.1
Jaenisch, R.2
-
66
-
-
72249119297
-
Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells
-
Peng JC, Valouev A, Swigut T, Zhang J, Zhao Y, Sidow A, Wysocka J (2009) Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell 139:1290-1302
-
(2009)
Cell
, vol.139
, pp. 1290-1302
-
-
Peng, J.C.1
Valouev, A.2
Swigut, T.3
Zhang, J.4
Zhao, Y.5
Sidow, A.6
Wysocka, J.7
-
67
-
-
0242668706
-
Role of histone H3 lysine 27 methylation in X inactivation
-
Plath K, Fang J, Mlynarczyk-Evans SK, Cao R, Worringer KA, Wang H, de la Cruz CC, Otte AP, Panning B, Zhang Y (2003) Role of histone H3 lysine 27 methylation in X inactivation. Science (New York, NY) 300:131-135
-
(2003)
Science (New York, NY
, vol.300
, pp. 131-135
-
-
Plath, K.1
Fang, J.2
Mlynarczyk-Evans, S.K.3
Cao, R.4
Worringer, K.A.5
Wang, H.6
De La Cruz, C.C.7
Otte, A.P.8
Panning, B.9
Zhang, Y.10
-
68
-
-
33846156141
-
F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses
-
Poueymirou WT, Auerbach W, Frendewey D, Hickey JF, Escaravage JM, Esau L, Dore AT, Stevens S, Adams NC, Dominguez MG, Gale NW, Yancopoulos GD, DeChiara TM, Valenzuela DM (2007) F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses. Nat Biotechnol 25:91-99
-
(2007)
Nat Biotechnol
, vol.25
, pp. 91-99
-
-
Poueymirou, W.T.1
Auerbach, W.2
Frendewey, D.3
Hickey, J.F.4
Escaravage, J.M.5
Esau, L.6
Dore, A.T.7
Stevens, S.8
Adams, N.C.9
Dominguez, M.G.10
Gale, N.W.11
Yancopoulos, G.D.12
DeChiara, T.M.13
Valenzuela, D.M.14
-
69
-
-
77950354829
-
The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation
-
Pullirsch D, Hartel R, Kishimoto H, Leeb M, Steiner G,Wutz A (2010) The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation. Development 137:935-943
-
(2010)
Development
, vol.137
, pp. 935-943
-
-
Pullirsch, D.1
Hartel, R.2
Kishimoto, H.3
Leeb, M.4
Steiner, G.5
Wutz, A.6
-
70
-
-
74349118193
-
Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2
-
Ralston A, Cox BJ, Nishioka N, Sasaki H, Chea E, Rugg-Gunn P, Guo G, Robson P, Draper JS, Rossant J (2010) Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2. Development 137:395-403
-
(2010)
Development
, vol.137
, pp. 395-403
-
-
Ralston, A.1
Cox, B.J.2
Nishioka, N.3
Sasaki, H.4
Chea, E.5
Rugg-Gunn, P.6
Guo, G.7
Robson, P.8
Draper, J.S.9
Rossant, J.10
-
71
-
-
34250729138
-
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
-
Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, Chang HY (2007) Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 129:1311-1323
-
(2007)
Cell
, vol.129
, pp. 1311-1323
-
-
Rinn, J.L.1
Kertesz, M.2
Wang, J.K.3
Squazzo, S.L.4
Xu, X.5
Brugmann, S.A.6
Goodnough, L.H.7
Helms, J.A.8
Farnham, P.J.9
Segal, E.10
Chang, H.Y.11
-
72
-
-
33845985573
-
Stem cells and lineage development in the mammalian blastocyst
-
Rossant J (2007) Stem cells and lineage development in the mammalian blastocyst. Reprod Fertil Dev 19:111-118
-
(2007)
Reprod Fertil Dev
, vol.19
, pp. 111-118
-
-
Rossant, J.1
-
73
-
-
0034665756
-
X inactivation in the mouse embryo deficient for Dnmt1: Distinct effect of hypomethylation on imprinted and random X inactivation
-
Sado T, Fenner MH, Tan SS, Tam P, Shioda T, Li E (2000) X inactivation in the mouse embryo deficient for Dnmt1: Distinct effect of hypomethylation on imprinted and random X inactivation. Dev Biol 225:294-303
-
(2000)
Dev Biol
, vol.225
, pp. 294-303
-
-
Sado, T.1
Fenner, M.H.2
Tan, S.S.3
Tam, P.4
Shioda, T.5
Li, E.6
-
74
-
-
77957824513
-
DNA methylation is dispensable for the growth and survival of the extraembryonic lineages
-
Sakaue M, Ohta H, Kumaki Y, Oda M, Sakaide Y, Matsuoka C, Yamagiwa A, Niwa H, Wakayama T, Okano M (2010) DNA methylation is dispensable for the growth and survival of the extraembryonic lineages. Curr Biol 20:1452-1457
-
(2010)
Curr Biol
, vol.20
, pp. 1452-1457
-
-
Sakaue, M.1
Ohta, H.2
Kumaki, Y.3
Oda, M.4
Sakaide, Y.5
Matsuoka, C.6
Yamagiwa, A.7
Niwa, H.8
Wakayama, T.9
Okano, M.10
-
75
-
-
77950223473
-
Mechanisms of trophectoderm fate specification in preimplantation mouse development
-
Sasaki H (2010) Mechanisms of trophectoderm fate specification in preimplantation mouse development. Dev Growth Differ 52:263-273
-
(2010)
Dev Growth Differ
, vol.52
, pp. 263-273
-
-
Sasaki, H.1
-
76
-
-
77952429798
-
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
-
Scheuermann JC, de Ayala Alonso AG, Oktaba K, Ly-Hartig N, McGinty RK, Fraterman S, Wilm M, Muir TW, Muller J (2010) Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. Nature 465:243-247
-
(2010)
Nature
, vol.465
, pp. 243-247
-
-
Scheuermann, J.C.1
De Ayala Alonso, A.G.2
Oktaba, K.3
Ly-Hartig, N.4
McGinty, R.K.5
Fraterman, S.6
Wilm, M.7
Muir, T.W.8
Muller, J.9
-
77
-
-
33746407708
-
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
-
Schoeftner S, Sengupta AK, Kubicek S, Mechtler K, Spahn L, Koseki H, Jenuwein T, Wutz A (2006) Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing. EMBO J 25:3110-3122
-
(2006)
EMBO J
, vol.25
, pp. 3110-3122
-
-
Schoeftner, S.1
Sengupta, A.K.2
Kubicek, S.3
Mechtler, K.4
Spahn, L.5
Koseki, H.6
Jenuwein, T.7
Wutz, A.8
-
78
-
-
33847084602
-
Genome regulation by polycomb and trithorax proteins
-
Schuettengruber B, Chourrout D, Vervoort M, Leblanc B, Cavalli G (2007) Genome regulation by polycomb and trithorax proteins. Cell 128:735-745
-
(2007)
Cell
, vol.128
, pp. 735-745
-
-
Schuettengruber, B.1
Chourrout, D.2
Vervoort, M.3
Leblanc, B.4
Cavalli, G.5
-
79
-
-
77951428293
-
UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis
-
Seenundun S, Rampalli S, Liu QC, Aziz A, Palii C, Hong S, Blais A, Brand M, Ge K, Dilworth FJ (2010) UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO J 29:1401-1411
-
(2010)
EMBO J
, vol.29
, pp. 1401-1411
-
-
Seenundun, S.1
Rampalli, S.2
Liu, Q.C.3
Aziz, A.4
Palii, C.5
Hong, S.6
Blais, A.7
Brand, M.8
Ge, K.9
Dilworth, F.J.10
-
80
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
-
Sharif J, Muto M, Takebayashi S, Suetake I, Iwamatsu A, Endo TA, Shinga J, Mizutani-Koseki Y, Toyoda T, Okamura K, Tajima S, Mitsuya K, Okano M, Koseki H (2007) The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 450:908-912
-
(2007)
Nature
, vol.450
, pp. 908-912
-
-
Sharif, J.1
Muto, M.2
Takebayashi, S.3
Suetake, I.4
Iwamatsu, A.5
Endo, T.A.6
Shinga, J.7
Mizutani-Koseki, Y.8
Toyoda, T.9
Okamura, K.10
Tajima, S.11
Mitsuya, K.12
Okano, M.13
Koseki, H.14
-
81
-
-
77954676296
-
Origin of the polycomb repressive complex 2 and gene silencing by an E(z) homolog in the unicellular alga Chlamydomonas
-
Shaver S, Casas-Mollano JA, Cerny RL, Cerutti H (2010) Origin of the polycomb repressive complex 2 and gene silencing by an E(z) homolog in the unicellular alga Chlamydomonas. Epigenetics 5:301-312
-
(2010)
Epigenetics
, vol.5
, pp. 301-312
-
-
Shaver, S.1
Casas-Mollano, J.A.2
Cerny, R.L.3
Cerutti, H.4
-
82
-
-
72249104107
-
Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells
-
Shen X, Kim W, Fujiwara Y, Simon MD, Liu Y, Mysliwiec MR, Yuan GC, Lee Y, Orkin SH (2009) Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells. Cell 139:1303-1314
-
(2009)
Cell
, vol.139
, pp. 1303-1314
-
-
Shen, X.1
Kim, W.2
Fujiwara, Y.3
Simon, M.D.4
Liu, Y.5
Mysliwiec, M.R.6
Yuan, G.C.7
Lee, Y.8
Orkin, S.H.9
-
83
-
-
68749110887
-
Nanog is the gateway to the pluripotent ground state
-
Silva J, Nichols J, Theunissen TW, Guo G, van Oosten AL, Barrandon O, Wray J, Yamanaka S, Chambers I, Smith A (2009) Nanog is the gateway to the pluripotent ground state. Cell 138:722-737
-
(2009)
Cell
, vol.138
, pp. 722-737
-
-
Silva, J.1
Nichols, J.2
Theunissen, T.W.3
Guo, G.4
Van Oosten, A.L.5
Barrandon, O.6
Wray, J.7
Yamanaka, S.8
Chambers, I.9
Smith, A.10
-
84
-
-
36749089980
-
Ring1- mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
-
Stock JK, Giadrossi S, Casanova M, Brookes E, Vidal M, Koseki H, Brockdorff N, Fisher AG, Pombo A (2007) Ring1- mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells. Nat Cell Biol 9:1428-1435
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1428-1435
-
-
Stock, J.K.1
Giadrossi, S.2
Casanova, M.3
Brookes, E.4
Vidal, M.5
Koseki, H.6
Brockdorff, N.7
Fisher, A.G.8
Pombo, A.9
-
85
-
-
0037099413
-
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis
-
Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M, Fukuda M, Takeda N, Niida H, Kato H, Shinkai Y (2002) G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev 16:1779-1791
-
(2002)
Genes Dev
, vol.16
, pp. 1779-1791
-
-
Tachibana, M.1
Sugimoto, K.2
Nozaki, M.3
Ueda, J.4
Ohta, T.5
Ohki, M.6
Fukuda, M.7
Takeda, N.8
Niida, H.9
Kato, H.10
Shinkai, Y.11
-
86
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (New York, NY) 324:930-935
-
(2009)
Science (New York, NY
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
Rao, A.11
-
87
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan M, Luo H, Lee S, Jin F, Yang JS, Montellier E, Buchou T, Cheng Z, Rousseaux S, Rajagopal N, Lu Z, Ye Z, Zhu Q, Wysocka J, Ye Y, Khochbin S, Ren B, Zhao Y (2011) Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 146:1016-1028
-
(2011)
Cell
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
Luo, H.2
Lee, S.3
Jin, F.4
Yang, J.S.5
Montellier, E.6
Buchou, T.7
Cheng, Z.8
Rousseaux, S.9
Rajagopal, N.10
Lu, Z.11
Ye, Z.12
Zhu, Q.13
Wysocka, J.14
Ye, Y.15
Khochbin, S.16
Ren, B.17
Zhao, Y.18
-
88
-
-
34447528757
-
New cell lines from mouse epiblast share defining features with human embryonic stem cells
-
Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD (2007) New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448:196-199
-
(2007)
Nature
, vol.448
, pp. 196-199
-
-
Tesar, P.J.1
Chenoweth, J.G.2
Brook, F.A.3
Davies, T.J.4
Evans, E.P.5
Mack, D.L.6
Gardner, R.L.7
McKay, R.D.8
-
89
-
-
33745270104
-
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1
-
Tsumura A, Hayakawa T, Kumaki Y, Takebayashi S, Sakaue M, Matsuoka C, Shimotohno K, Ishikawa F, Li E, Ueda HR, Nakayama J, Okano M (2006) Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells 11:805-814
-
(2006)
Dnmt3a and Dnmt3b. Genes Cells
, vol.11
, pp. 805-814
-
-
Tsumura, A.1
Hayakawa, T.2
Kumaki, Y.3
Takebayashi, S.4
Sakaue, M.5
Matsuoka, C.6
Shimotohno, K.7
Ishikawa, F.8
Li, E.9
Ueda, H.R.10
Nakayama, J.11
Okano, M.12
-
90
-
-
0345269795
-
Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
-
Voncken JW, Roelen BA, Roefs M, de Vries S, Verhoeven E, Marino S, Deschamps J, van Lohuizen M (2003) Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition. Proc Natl Acad Sci USA 100:2468-2473
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2468-2473
-
-
Voncken, J.W.1
Roelen, B.A.2
Roefs, M.3
De Vries, S.4
Verhoeven, E.5
Marino, S.6
Deschamps, J.7
Van Lohuizen, M.8
-
91
-
-
0034934749
-
Imprinted X inactivation maintained by a mouse Polycomb group gene
-
Wang J, Mager J, Chen Y, Schneider E, Cross JC, Nagy A, Magnuson T (2001) Imprinted X inactivation maintained by a mouse Polycomb group gene. Nat Genet 28:371-375
-
(2001)
Nat Genet
, vol.28
, pp. 371-375
-
-
Wang, J.1
Mager, J.2
Chen, Y.3
Schneider, E.4
Cross, J.C.5
Nagy, A.6
Magnuson, T.7
-
92
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams K, Christensen J, Pedersen MT, Johansen JV, Cloos PA, Rappsilber J, Helin K (2011) TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473:343-348
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
Johansen, J.V.4
Cloos, P.A.5
Rappsilber, J.6
Helin, K.7
-
93
-
-
79956292024
-
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
-
Wu H, D'Alessio AC, Ito S, Xia K, Wang Z, Cui K, Zhao K, Eve Sun Y, Zhang Y (2011) Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 473:389-393
-
(2011)
Nature
, vol.473
, pp. 389-393
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Xia, K.4
Wang, Z.5
Cui, K.6
Zhao, K.7
Eve Sun, Y.8
Zhang, Y.9
-
94
-
-
67650095196
-
Elite and stochastic models for induced pluripotent stem cell generation
-
Yamanaka S (2009) Elite and stochastic models for induced pluripotent stem cell generation. Nature 460:49-52
-
(2009)
Nature
, vol.460
, pp. 49-52
-
-
Yamanaka, S.1
-
95
-
-
77149144362
-
ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage
-
Yeap LS, Hayashi K, Surani MA (2009) ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage. Epigenetics Chromatin 2:12
-
(2009)
Epigenetics Chromatin
, vol.2
, pp. 12
-
-
Yeap, L.S.1
Hayashi, K.2
Surani, M.A.3
-
96
-
-
84455167621
-
Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
-
Yildirim O, Li R, Hung JH, Chen PB, Dong X, Ee LS, Weng Z, Rando OJ, Fazzio TG (2011) Mbd3/NURD complex regulates expression of 5- hydroxymethylcytosine marked genes in embryonic stem cells. Cell 147:1498-1510
-
(2011)
Cell
, vol.147
, pp. 1498-1510
-
-
Yildirim, O.1
Li, R.2
Hung, J.H.3
Chen, P.B.4
Dong, X.5
Ee, L.S.6
Weng, Z.7
Rando, O.J.8
Fazzio, T.G.9
-
97
-
-
70350686165
-
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
-
Yuan P, Han J, Guo G, Orlov YL, Huss M, Loh YH, Yaw LP, Robson P, Lim B, Ng HH (2009) Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes Dev 23:2507-2520
-
(2009)
Genes Dev
, vol.23
, pp. 2507-2520
-
-
Yuan, P.1
Han, J.2
Guo, G.3
Orlov, Y.L.4
Huss, M.5
Loh, Y.H.6
Yaw, L.P.7
Robson, P.8
Lim, B.9
Ng, H.H.10
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