Anti-cancer effects of thymoquinone in mouse neuroblastoma (Neuro-2a) cells through caspase-3 activation with down-regulation of XIAP

Toxicology Letters

Volumn 213, Issue 2, 2012, Pages 151-159

  Paramasivam, Arumugam ^a   Sambantham, Shanmugam ^a   Shabnam, Jawahar ^a   Raghunandhakumar, Subramanian ^a   Anandan, Balakrishnan ^a   Rajiv, Rose ^b   Priyadharsini, Jayaseelan Vijayashree ^a   Jayaraman, Gopalswamy ^a  

^a UNIVERSITY OF MADRAS   (India)

^b U S ARMY MEDICAL RESEARCH AND MATERIEL COMMAND   (United States)

Author keywords

Apoptosis; Caspase; Neuroblastoma; Thymoquinone; XIAP

Indexed keywords

CASPASE 3; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; THYMOQUINONE; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLACK CUMIN; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVATION; MITOCHONDRION; MOUSE; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZOQUINONES; BLOTTING, WESTERN; CASPASE 3; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; NEUROBLASTOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

NIGELLA SATIVA;

EID: 84864468084     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.06.011     Document Type: Article

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