Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein

Toxicology in Vitro

Volumn 25, Issue 7, 2011, Pages 1392-1398

  Ng, Wei Keat ^a   Yazan, Latifah Saiful ^a   Ismail, Maznah ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Apoptosis; Bcl 2; Cervical cancer; Nigella sativa; P53; Thymoquinone

Indexed keywords

CISPLATIN; LIPOCORTIN 5; PROPIDIUM IODIDE; PROTEIN BCL 2; PROTEIN P53; THYMOQUINONE; TRYPAN BLUE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLACK CUMIN; CARCINOMA CELL; CELL CYCLE G1 PHASE; CELL STRUCTURE; COMPARATIVE EFFECTIVENESS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENCY; EMBRYO; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; UTERINE CERVIX CARCINOMA;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOQUINONES; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITORY CONCENTRATION 50; MICE; NIGELLA SATIVA; PROTO-ONCOGENE PROTEINS C-BCL-2; UTERINE CERVICAL NEOPLASMS; VERO CELLS;

NIGELLA SATIVA;

EID: 84860390247     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.04.030     Document Type: Article

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