Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma

Free Radical Biology and Medicine

Volumn 50, Issue 8, 2011, Pages 978-987

  Hussain, Azhar R ^a   Ahmed, Maqbool ^a   Ahmed, Saeeda ^a   Manogaran, Pulicat ^a   Platanias, Leonidas C ^b   Alvi, Syed N ^a   Al Kuraya, Khawla S ^a   Uddin, Shahab ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Cell death; Free radicals; NHL therapy; Primary effusion lymphoma; Thymoquinone

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE 9; CYTOCHROME C; DEATH RECEPTOR 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; THYMOQUINONE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL LOSS; CELL PROLIFERATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIMARY EFFUSION LYMPHOMA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN SECRETION; RECEPTOR UPREGULATION;

APOPTOSIS; BENZOQUINONES; BLOTTING, WESTERN; CELL DIVISION; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE SILENCING; HUMANS; IN SITU NICK-END LABELING; LYMPHOMA, PRIMARY EFFUSION; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING;

NIGELLA SATIVA;

EID: 79952446077     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.12.034     Document Type: Article

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