Antagonizing XIAP-mediated caspase-3 inhibition: Achilles' heel of cancers?

Cancer Cell

Volumn 5, Issue 1, 2004, Pages 1-2

  Huang, Yihua ^a   Lu, Miao ^a   Wu, Hao ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; CASPASE 3; CASPASE 7; CASPASE 9; CELL DNA; DOXORUBICIN; ENZYME PRECURSOR; ETOPOSIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN DERIVATIVE; PROTEIN INHIBITOR; PROTEIN XAF1; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE PROTEINASE OMI; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

AMINO TERMINAL SEQUENCE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER; CANCER CELL; CANCER MODEL; CELL DEATH; CELL DESTRUCTION; CELL KILLING; CELL SURVIVAL; COMBINATORIAL LIBRARY; DIMERIZATION; DNA DAMAGE; DROSOPHILA; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; LEUKEMIA CELL LINE; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SHORT SURVEY; SIGNAL TRANSDUCTION; SOLID TUMOR; TUMOR CELL; TUMOR XENOGRAFT;

MAMMALIA;

EID: 1642512653     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(03)00340-4     Document Type: Review

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