-
1
-
-
30944439493
-
TGFbeta pathobiology in the eye
-
Saika S. TGFbeta pathobiology in the eye. Lab. Invest. 2006; 86: 106-15.
-
(2006)
Lab. Invest.
, vol.86
, pp. 106-115
-
-
Saika, S.1
-
2
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003; 425: 577-84.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
3
-
-
43149103190
-
Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle
-
Dadlani H, Ballinger ML, Osman N, Getachew R, Little PJ. Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle. J. Biol. Chem. 2008; 283: 7844-52.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 7844-7852
-
-
Dadlani, H.1
Ballinger, M.L.2
Osman, N.3
Getachew, R.4
Little, P.J.5
-
4
-
-
0031685620
-
TGF-beta signal transduction
-
Massague J. TGF-beta signal transduction. Annu. Rev. Biochem. 1998; 67: 753-91.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
6
-
-
0036177334
-
Crystal structure of the human TbetaR2 ectodomain-TGF-beta3 complex
-
Hart PJ, Deep S, Taylor AB, Shu Z, Hinck CS, Hinck AP. Crystal structure of the human TbetaR2 ectodomain-TGF-beta3 complex. Nat. Struct. Biol. 2002; 9: 203-8.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 203-208
-
-
Hart, P.J.1
Deep, S.2
Taylor, A.B.3
Shu, Z.4
Hinck, C.S.5
Hinck, A.P.6
-
7
-
-
11844263366
-
Transforming growth factor-beta, cell signaling and cardiovascular disorders
-
Agrotis A, Kalinina N, Bobik A. Transforming growth factor-beta, cell signaling and cardiovascular disorders. Curr. Vasc. Pharmacol. 2005; 3: 55-61.
-
(2005)
Curr. Vasc. Pharmacol.
, vol.3
, pp. 55-61
-
-
Agrotis, A.1
Kalinina, N.2
Bobik, A.3
-
8
-
-
0033524943
-
Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12
-
Huse M, Chen YG, Massague J, Kuriyan J. Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell 1999; 96: 425-36.
-
(1999)
Cell
, vol.96
, pp. 425-436
-
-
Huse, M.1
Chen, Y.G.2
Massague, J.3
Kuriyan, J.4
-
9
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003; 113: 685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
10
-
-
78649982907
-
The dynamic roles of TGF-beta in cancer
-
Meulmeester E, Ten Dijke P. The dynamic roles of TGF-beta in cancer. J. Pathol. 2011; 223: 205-18.
-
(2011)
J. Pathol.
, vol.223
, pp. 205-218
-
-
Meulmeester, E.1
Ten Dijke, P.2
-
11
-
-
0034796457
-
The TGF beta receptor activation process: An inhibitor- to substrate-binding switch
-
Huse M, Muir TW, Xu L, Chen YG, Kuriyan J, Massague J. The TGF beta receptor activation process: An inhibitor- to substrate-binding switch. Mol. Cell 2001; 8: 671-82.
-
(2001)
Mol. Cell
, vol.8
, pp. 671-682
-
-
Huse, M.1
Muir, T.W.2
Xu, L.3
Chen, Y.G.4
Kuriyan, J.5
Massague, J.6
-
12
-
-
67650466368
-
Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer
-
Matsuzaki K, Kitano C, Murata M et al. Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer. Cancer Res. 2009; 69: 5321-30.
-
(2009)
Cancer Res.
, vol.69
, pp. 5321-5330
-
-
Matsuzaki, K.1
Kitano, C.2
Murata, M.3
-
13
-
-
34247539528
-
A tale of two proteins. Differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling
-
Brown KA, Pietenpol JA, Moses HL. A tale of two proteins. Differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling. J. Cell. Biochem. 2007; 101: 9-33.
-
(2007)
J. Cell. Biochem.
, vol.101
, pp. 9-33
-
-
Brown, K.A.1
Pietenpol, J.A.2
Moses, H.L.3
-
14
-
-
58149216052
-
Signaling cross-talk between TGF-beta/BMP and other pathways
-
Guo X, Wang XF. Signaling cross-talk between TGF-beta/BMP and other pathways. Cell Res. 2009; 19: 71-88.
-
(2009)
Cell Res.
, vol.19
, pp. 71-88
-
-
Guo, X.1
Wang, X.F.2
-
15
-
-
44349085416
-
Structure-function relationship of inhibitory Smads: Structural flexibility contributes to functional divergence
-
Hariharan R, Pillai MR. Structure-function relationship of inhibitory Smads: Structural flexibility contributes to functional divergence. Proteins 2008; 71: 1853-62.
-
(2008)
Proteins
, vol.71
, pp. 1853-1862
-
-
Hariharan, R.1
Pillai, M.R.2
-
16
-
-
0035116044
-
Structural insights on Smad function in TGFbeta signaling
-
Shi Y. Structural insights on Smad function in TGFbeta signaling. Bioessays 2001; 23: 223-32.
-
(2001)
Bioessays
, vol.23
, pp. 223-232
-
-
Shi, Y.1
-
17
-
-
58149264873
-
Nucleocytoplasmic shuttling of Smad proteins
-
Hill CS. Nucleocytoplasmic shuttling of Smad proteins. Cell Res. 2009; 19: 36-46.
-
(2009)
Cell Res.
, vol.19
, pp. 36-46
-
-
Hill, C.S.1
-
18
-
-
10744224961
-
Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis
-
Xiao C, Shim JH, Kluppel M et al. Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. Genes Dev. 2003; 17: 2933-49.
-
(2003)
Genes Dev.
, vol.17
, pp. 2933-2949
-
-
Xiao, C.1
Shim, J.H.2
Kluppel, M.3
-
20
-
-
0032483544
-
Crystal structure of a Smad MH1 domain bound to DNA. Insights on DNA binding in TGF-beta signaling
-
Shi Y, Wang YF, Jayaraman L, Yang H, Massague J, Pavletich NP. Crystal structure of a Smad MH1 domain bound to DNA. Insights on DNA binding in TGF-beta signaling. Cell 1998; 94: 585-94.
-
(1998)
Cell
, vol.94
, pp. 585-594
-
-
Shi, Y.1
Wang, Y.F.2
Jayaraman, L.3
Yang, H.4
Massague, J.5
Pavletich, N.P.6
-
21
-
-
0033104503
-
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta
-
Yang X, Letterio JJ, Lechleider RJ et al. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. EMBO J. 1999; 18: 1280-91.
-
(1999)
EMBO J.
, vol.18
, pp. 1280-1291
-
-
Yang, X.1
Letterio, J.J.2
Lechleider, R.J.3
-
22
-
-
70349659185
-
Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways. The role of Smad3
-
Yang F, Chung AC, Huang XR, Lan HY. Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways. The role of Smad3. Hypertension 2009; 54: 877-84.
-
(2009)
Hypertension
, vol.54
, pp. 877-884
-
-
Yang, F.1
Chung, A.C.2
Huang, X.R.3
Lan, H.Y.4
-
23
-
-
0033602186
-
A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3
-
Dennler S, Huet S, Gauthier JM. A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3. Oncogene 1999; 18: 1643-8.
-
(1999)
Oncogene
, vol.18
, pp. 1643-1648
-
-
Dennler, S.1
Huet, S.2
Gauthier, J.M.3
-
24
-
-
0033534573
-
Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3
-
Yagi K, Goto D, Hamamoto T, Takenoshita S, Kato M, Miyazono K. Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3. J. Biol. Chem. 1999; 274: 703-9.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 703-709
-
-
Yagi, K.1
Goto, D.2
Hamamoto, T.3
Takenoshita, S.4
Kato, M.5
Miyazono, K.6
-
25
-
-
65649084845
-
Transforming growth factor-{beta}-inducible phosphorylation of Smad3
-
Wang G, Matsuura I, He D, Liu F. Transforming growth factor-{beta}-inducible phosphorylation of Smad3. J. Biol. Chem. 2009; 284: 9663-73.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 9663-9673
-
-
Wang, G.1
Matsuura, I.2
He, D.3
Liu, F.4
-
26
-
-
78650982203
-
Smad linker region phosphorylation in the regulation of extracellular matrix synthesis
-
Burch ML, Zheng W, Little PJ. Smad linker region phosphorylation in the regulation of extracellular matrix synthesis. Cell. Mol. Life Sci. 2011; 68: 97-107.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 97-107
-
-
Burch, M.L.1
Zheng, W.2
Little, P.J.3
-
27
-
-
0033106484
-
A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras
-
Kretzschmar M, Doody J, Timokhina I, Massague J. A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras. Genes Dev. 1999; 13: 804-16.
-
(1999)
Genes Dev.
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massague, J.4
-
28
-
-
77953025465
-
TGF-β stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad 2
-
Burch ML, Yang SN, Ballinger ML, Getachew R, Osman N, Little PJ. TGF-β stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad 2. Cell. Mol. Life Sci. 2010; 67: 2077-90.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 2077-2090
-
-
Burch, M.L.1
Yang, S.N.2
Ballinger, M.L.3
Getachew, R.4
Osman, N.5
Little, P.J.6
-
29
-
-
65549170041
-
Quantitative modeling and analysis of the transforming growth factor beta signaling pathway
-
Chung SW, Miles FL, Sikes RA, Cooper CR, Farach-Carson MC, Ogunnaike BA. Quantitative modeling and analysis of the transforming growth factor beta signaling pathway. Biophys. J. 2009; 96: 1733-50.
-
(2009)
Biophys. J.
, vol.96
, pp. 1733-1750
-
-
Chung, S.W.1
Miles, F.L.2
Sikes, R.A.3
Cooper, C.R.4
Farach-Carson, M.C.5
Ogunnaike, B.A.6
-
30
-
-
58149239730
-
Phospho-control of TGF-beta superfamily signaling
-
Wrighton KH, Lin X, Feng XH. Phospho-control of TGF-beta superfamily signaling. Cell Res. 2009; 19: 8-20.
-
(2009)
Cell Res.
, vol.19
, pp. 8-20
-
-
Wrighton, K.H.1
Lin, X.2
Feng, X.H.3
-
31
-
-
0031773264
-
TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein
-
Shen X, Hu PP, Liberati NT, Datto MB, Frederick JP, Wang XF. TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein. Mol. Biol. Cell 1998; 9: 3309-19.
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 3309-3319
-
-
Shen, X.1
Hu, P.P.2
Liberati, N.T.3
Datto, M.B.4
Frederick, J.P.5
Wang, X.F.6
-
32
-
-
0039925710
-
Relationship between the renin-angiotensin system genes and diabetic nephropathy in the Chinese
-
Wu S, Xiang K, Zheng T et al. Relationship between the renin-angiotensin system genes and diabetic nephropathy in the Chinese. Chin. Med. J. 2000; 113: 437-41.
-
(2000)
Chin. Med. J.
, vol.113
, pp. 437-441
-
-
Wu, S.1
Xiang, K.2
Zheng, T.3
-
33
-
-
18244362844
-
Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling
-
Wu JW, Hu M, Chai J et al. Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling. Mol. Cell 2001; 8: 1277-89.
-
(2001)
Mol. Cell
, vol.8
, pp. 1277-1289
-
-
Wu, J.W.1
Hu, M.2
Chai, J.3
-
34
-
-
0030926005
-
A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity
-
Feng XH, Derynck R. A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity. EMBO J. 1997; 16: 3912-23.
-
(1997)
EMBO J.
, vol.16
, pp. 3912-3923
-
-
Feng, X.H.1
Derynck, R.2
-
35
-
-
0030613249
-
TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling
-
Abdollah S, Macias-Silva M, Tsukazaki T, Hayashi H, Attisano L, Wrana JL. TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling. J. Biol. Chem. 1997; 272: 27678-85.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27678-27685
-
-
Abdollah, S.1
Macias-Silva, M.2
Tsukazaki, T.3
Hayashi, H.4
Attisano, L.5
Wrana, J.L.6
-
37
-
-
0033568923
-
Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes
-
Howell M, Itoh F, Pierreux CE et al. Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes. Dev. Biol. 1999; 214: 354-69.
-
(1999)
Dev. Biol.
, vol.214
, pp. 354-369
-
-
Howell, M.1
Itoh, F.2
Pierreux, C.E.3
-
38
-
-
0035814804
-
Sedimentation studies reveal a direct role of phosphorylation in Smad3. Smad4 homo- and hetero-trimerization
-
Correia JJ, Chacko BM, Lam SS, Lin K. Sedimentation studies reveal a direct role of phosphorylation in Smad3. Smad4 homo- and hetero-trimerization. Biochemistry 2001; 40: 1473-82.
-
(2001)
Biochemistry
, vol.40
, pp. 1473-1482
-
-
Correia, J.J.1
Chacko, B.M.2
Lam, S.S.3
Lin, K.4
-
39
-
-
0030773834
-
Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1
-
Kretzschmar M, Doody J, Massague J. Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1. Nature 1997; 389: 618-22.
-
(1997)
Nature
, vol.389
, pp. 618-622
-
-
Kretzschmar, M.1
Doody, J.2
Massague, J.3
-
40
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature 2001; 410: 37-40.
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
41
-
-
20244376914
-
Transforming growth factor-beta and platelet-derived growth factor signal via c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury
-
Yoshida K, Matsuzaki K, Mori S et al. Transforming growth factor-beta and platelet-derived growth factor signal via c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury. Am. J. Pathol. 2005; 166: 1029-39.
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 1029-1039
-
-
Yoshida, K.1
Matsuzaki, K.2
Mori, S.3
-
42
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
-
Yamaguchi K, Shirakabe K, Shibuya H et al. Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 1995; 270: 2008-11.
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
-
43
-
-
24644476507
-
Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: Implications for carcinogenesis
-
Javelaud D, Mauviel A. Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: Implications for carcinogenesis. Oncogene 2005; 24: 5742-50.
-
(2005)
Oncogene
, vol.24
, pp. 5742-5750
-
-
Javelaud, D.1
Mauviel, A.2
-
44
-
-
24944497786
-
Non-Smad TGF-beta signals
-
Moustakas A, Heldin CH. Non-Smad TGF-beta signals. J. Cell Sci. 2005; 118: 3573-84.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.H.2
-
45
-
-
0346594337
-
Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction
-
Pera EM, Ikeda A, Eivers E, De Robertis EM. Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev. 2003; 17: 3023-8.
-
(2003)
Genes Dev.
, vol.17
, pp. 3023-3028
-
-
Pera, E.M.1
Ikeda, A.2
Eivers, E.3
De Robertis, E.M.4
-
46
-
-
6044261233
-
TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions
-
Mori S, Matsuzaki K, Yoshida K et al. TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions. Oncogene 2004; 23: 7416-29.
-
(2004)
Oncogene
, vol.23
, pp. 7416-7429
-
-
Mori, S.1
Matsuzaki, K.2
Yoshida, K.3
-
47
-
-
67749106488
-
A negative feedback control of transforming growth factor-beta signaling by glycogen synthase kinase 3-mediated Smad3 linker phosphorylation at Ser-204
-
Millet C, Yamashita M, Heller M, Yu LR, Veenstra TD, Zhang YE. A negative feedback control of transforming growth factor-beta signaling by glycogen synthase kinase 3-mediated Smad3 linker phosphorylation at Ser-204. J. Biol. Chem. 2009; 284: 19808-16.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 19808-19816
-
-
Millet, C.1
Yamashita, M.2
Heller, M.3
Yu, L.R.4
Veenstra, T.D.5
Zhang, Y.E.6
-
48
-
-
19944429743
-
Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis
-
Yamagata H, Matsuzaki K, Mori S et al. Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis. Cancer Res. 2005; 65: 157-65.
-
(2005)
Cancer Res.
, vol.65
, pp. 157-165
-
-
Yamagata, H.1
Matsuzaki, K.2
Mori, S.3
-
49
-
-
33646794060
-
Essential role of Smad3 in angiotensin II-induced vascular fibrosis
-
Wang W, Huang XR, Canlas E et al. Essential role of Smad3 in angiotensin II-induced vascular fibrosis. Circ. Res. 2006; 98: 1032-9.
-
(2006)
Circ. Res.
, vol.98
, pp. 1032-1039
-
-
Wang, W.1
Huang, X.R.2
Canlas, E.3
-
50
-
-
1342268353
-
Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: Implications for diabetic renal and vascular disease
-
Li JH, Huang XR, Zhu HJ et al. Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: Implications for diabetic renal and vascular disease. FASEB J. 2004; 18: 176-8.
-
(2004)
FASEB J.
, vol.18
, pp. 176-178
-
-
Li, J.H.1
Huang, X.R.2
Zhu, H.J.3
-
51
-
-
73849126315
-
Rho-kinase inhibitors as therapeutics: From pan inhibition to isoform selectivity
-
Hahmann C, Schroeter T. Rho-kinase inhibitors as therapeutics: From pan inhibition to isoform selectivity. Cell. Mol. Life Sci. 2010; 67: 171-7.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 171-177
-
-
Hahmann, C.1
Schroeter, T.2
-
52
-
-
0346690411
-
TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest
-
Bhowmick NA, Ghiassi M, Aakre M, Brown K, Singh V, Moses HL. TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest. Proc. Natl Acad. Sci. USA 2003; 100: 15548-53.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 15548-15553
-
-
Bhowmick, N.A.1
Ghiassi, M.2
Aakre, M.3
Brown, K.4
Singh, V.5
Moses, H.L.6
-
53
-
-
12544257249
-
Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo
-
Kamaraju AK, Roberts AB. Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo. J. Biol. Chem. 2005; 280: 1024-36.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1024-1036
-
-
Kamaraju, A.K.1
Roberts, A.B.2
-
54
-
-
33644974307
-
RhoA modulates Smad signaling during transforming growth factor-beta-induced smooth muscle differentiation
-
Chen S, Crawford M, Day RM et al. RhoA modulates Smad signaling during transforming growth factor-beta-induced smooth muscle differentiation. J. Biol. Chem. 2006; 281: 1765-70.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1765-1770
-
-
Chen, S.1
Crawford, M.2
Day, R.M.3
-
55
-
-
3142546336
-
Cyclin-dependent kinases regulate the antiproliferative function of Smads
-
Matsuura I, Denissova NG, Wang G, He D, Long J, Liu F. Cyclin-dependent kinases regulate the antiproliferative function of Smads. Nature 2004; 430: 226-31.
-
(2004)
Nature
, vol.430
, pp. 226-231
-
-
Matsuura, I.1
Denissova, N.G.2
Wang, G.3
He, D.4
Long, J.5
Liu, F.6
-
56
-
-
70350780570
-
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways
-
Alarcon C, Zaromytidou AI, Xi Q et al. Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell 2009; 139: 757-69.
-
(2009)
Cell
, vol.139
, pp. 757-769
-
-
Alarcon, C.1
Zaromytidou, A.I.2
Xi, Q.3
-
58
-
-
59049094551
-
A last-minute rescue of trapped chromatin
-
Chen CT, Doxsey S. A last-minute rescue of trapped chromatin. Cell 2009; 136: 397-9.
-
(2009)
Cell
, vol.136
, pp. 397-399
-
-
Chen, C.T.1
Doxsey, S.2
-
59
-
-
0347991862
-
Integration of Smad and MAPK pathways: A link and a linker revisited
-
Massague J. Integration of Smad and MAPK pathways: A link and a linker revisited. Genes Dev. 2003; 17: 2993-7.
-
(2003)
Genes Dev.
, vol.17
, pp. 2993-2997
-
-
Massague, J.1
-
60
-
-
0028168242
-
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
-
Hannon GJ, Beach D. p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature 1994; 371: 257-61.
-
(1994)
Nature
, vol.371
, pp. 257-261
-
-
Hannon, G.J.1
Beach, D.2
-
61
-
-
58149218252
-
Regulating the stability of TGFbeta receptors and Smads
-
Lonn P, Moren A, Raja E, Dahl M, Moustakas A. Regulating the stability of TGFbeta receptors and Smads. Cell Res. 2009; 19: 21-35.
-
(2009)
Cell Res.
, vol.19
, pp. 21-35
-
-
Lonn, P.1
Moren, A.2
Raja, E.3
Dahl, M.4
Moustakas, A.5
-
62
-
-
70350785179
-
Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling
-
Gao S, Alarcon C, Sapkota G et al. Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling. Mol. Cell 2009; 36: 457-68.
-
(2009)
Mol. Cell
, vol.36
, pp. 457-468
-
-
Gao, S.1
Alarcon, C.2
Sapkota, G.3
|