Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle

Journal of Biological Chemistry

Volumn 283, Issue 12, 2008, Pages 7844-7852

  Dadlani, Harsha ^a,c   Ballinger, Mandy L ^a   Osman, Narin ^a,b   Getachew, Robel ^a   Little, Peter J ^a,b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSEL PROSTHESES; CELL GROWTH; CHEMICAL REACTIONS; CHROMATOGRAPHIC ANALYSIS; GLYCOPROTEINS; MAPS; MUSCLE; PHOSPHORYLATION;

ATHEROGENESIS; ATHEROSCLEROTIC LESIONS; CARDIOVASCULAR DISEASES; CHAIN SIZES; CORE PROTEINS; CRITICAL COMPONENTS; DENSITY LIPOPROTEINS; GLUCOSAMINE; GLYCOSAMINOGLYCAN; GLYCOSAMINOGLYCANS; MAP KINASE SIGNALING; MAP KINASES; PATHOLOGICAL PROCESSES; PHOSPHORYLATION PATHWAYS; POTENTIAL THERAPEUTIC TARGETS; PROTEOGLYCAN; PROTEOGLYCAN SYNTHESIS; PROTEOGLYCANS; SIGNALING PATHWAYS; SIZE EXCLUSIONS; TRANSFORMING GROWTH FACTORS; VASCULAR SMOOTH MUSCLE CELLS; VASCULAR SMOOTH MUSCLES;

SIZE EXCLUSION CHROMATOGRAPHY;

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; CORE PROTEIN; CYSTEINE; GLUCOSAMINE; GLYCOSAMINOGLYCAN; LOW DENSITY LIPOPROTEIN; METHIONINE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROTEOGLYCAN; SMAD2 PROTEIN; SMAD3 PROTEIN; SULFATE; SULFUR 35; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; ENZYME INHIBITOR; PROTEIN SERINE THREONINE KINASE; SMAD2 PROTEIN, HUMAN; SMAD3 PROTEIN, HUMAN; TGF BETA TYPE I RECEPTOR; TGF-BETA TYPE I RECEPTOR;

ARTICLE; ATHEROGENESIS; CONTROLLED STUDY; ENZYME INHIBITION; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEOGLYCAN SYNTHESIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; ATHEROSCLEROSIS; BIOSYNTHESIS; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PATHOLOGY;

ATHEROSCLEROSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; LIPOPROTEINS, LDL; MAP KINASE SIGNALING SYSTEM; MUSCLE, SMOOTH, VASCULAR; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEOGLYCANS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SMAD2 PROTEIN; SMAD3 PROTEIN; SULFATES; TRANSFORMING GROWTH FACTOR BETA;

EID: 43149103190     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M703125200     Document Type: Article

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