Synthetic biology with surgical precision: Targeted reengineering of signaling proteins

Cellular Signalling

Volumn 24, Issue 10, 2012, Pages 1899-1908

  Gurevich, Vsevolod V ^a   Gurevich, Eugenia V ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Arrestin; Cell death; Cell signaling; Cell survival; GPCR; Protein engineering; Scaffold protein; Signaling pathways

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 6; JANUS KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MUSCARINIC RECEPTOR; PROTEIN ARRESTIN 1; PROTEIN ARRESTIN 2; PROTEIN ARRESTIN 3; PROTEIN TYROSINE KINASE; RETINA S ANTIGEN; UNCLASSIFIED DRUG;

BINDING AFFINITY; CELL DEGENERATION; COLOR BLINDNESS; HUMAN; MUTATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RECEPTOR BINDING; RETINA DEGENERATION; REVIEW;

ANIMALS; ARRESTIN; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, MOLECULAR; PROTEIN ENGINEERING; PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; SYNTHETIC BIOLOGY;

EID: 84864008533     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.05.012     Document Type: Review

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