-
1
-
-
2942731519
-
Crystal structure of the membrane fusion protein, MexA of the multidrug transporter in Pseudomonas aeruginosa
-
Akama, H., T. Matsuura, S. Kashiwagi, H. Yoneyama, T. Tsukihara, A. Nakagawa, and T. Nakae. 2004. Crystal structure of the membrane fusion protein, MexA of the multidrug transporter in Pseudomonas aeruginosa. J. Biol. Chem. 279:25939-25942.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25939-25942
-
-
Akama, H.1
Matsuura, T.2
Kashiwagi, S.3
Yoneyama, H.4
Tsukihara, T.5
Nakagawa, A.6
Nakae, T.7
-
2
-
-
0035782880
-
Lipid-layer crystallization and preliminary three-dimensional structural analysis of AcrA, the periplasmic component of a bacterial multidrug efflux pump
-
Avila-Sakar, A. J., S. Misaghi, E. M. Wilson-Kubalek, K. H. Downing, H. Zgurskaya, H. Nikaido, and E. Nogales. 2001. Lipid-layer crystallization and preliminary three-dimensional structural analysis of AcrA, the periplasmic component of a bacterial multidrug efflux pump. J. Struct. Biol. 136:81-88.
-
(2001)
J. Struct. Biol.
, vol.136
, pp. 81-88
-
-
Avila-Sakar, A.J.1
Misaghi, S.2
Wilson-Kubalek, E.M.3
Downing, K.H.4
Zgurskaya, H.5
Nikaido, H.6
Nogales, E.7
-
3
-
-
0019883199
-
Pyranine (8-hydroxy-1,3,6-pyrenetrisulfonate) as a probe of internal aqueous hydrogen ion concentration in phospholipid vesicles
-
Clement, N. R., and J. M. Gould. 1981. Pyranine (8-hydroxy-1,3,6- pyrenetrisulfonate) as a probe of internal aqueous hydrogen ion concentration in phospholipid vesicles. Biochemistry 20:1534-1544.
-
(1981)
Biochemistry
, vol.20
, pp. 1534-1544
-
-
Clement, N.R.1
Gould, J.M.2
-
4
-
-
0025738363
-
Purification and characterization of the membrane-associated components of the maltose transport system from Escherichia coli
-
Davidson, A. L., and H. Nikaido. 1991. Purification and characterization of the membrane-associated components of the maltose transport system from Escherichia coli J. Biol. Chem. 266:8946-8951.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 8946-8951
-
-
Davidson, A.L.1
Nikaido, H.2
-
5
-
-
0028318241
-
A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria
-
Dinh, T., I. T. Paulsen, and M. H. Saier, Jr. 1994. A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria. J. Bacteriol. 176:3825-3831.
-
(1994)
J. Bacteriol.
, vol.176
, pp. 3825-3831
-
-
Dinh, T.1
Paulsen, I.T.2
Saier Jr., M.H.3
-
6
-
-
0036889033
-
Substrate specificity of the RND-type multidrug efflux pumps AcrB and AcrD of Escherichia coli is determined predominantly by two large periplasmic loops
-
Elkins, C. A., and H. Nikaido. 2002. Substrate specificity of the RND-type multidrug efflux pumps AcrB and AcrD of Escherichia coli is determined predominantly by two large periplasmic loops. J. Bacteriol. 184:6490-6498.
-
(2002)
J. Bacteriol.
, vol.184
, pp. 6490-6498
-
-
Elkins, C.A.1
Nikaido, H.2
-
7
-
-
0042838181
-
Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pump
-
Elkins, C. A., and H. Nikaido. 2003. Chimeric analysis of AcrA function reveals the importance of its C-terminal domain in its interaction with the AcrB multidrug efflux pump. J. Bacteriol. 185:5349-5356.
-
(2003)
J. Bacteriol.
, vol.185
, pp. 5349-5356
-
-
Elkins, C.A.1
Nikaido, H.2
-
8
-
-
0029796966
-
Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli
-
Fralick, J. A. 1996. Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli. J. Bacteriol. 178:5803-5805.
-
(1996)
J. Bacteriol.
, vol.178
, pp. 5803-5805
-
-
Fralick, J.A.1
-
9
-
-
0033543578
-
Energetics and topology of CzcA, a cation/proton antiporter of the resistance-nodulation-cell division protein family
-
Goldberg, M., T. Pribyl, S. Juhnke, and D. H. Nies. 1999. Energetics and topology of CzcA, a cation/proton antiporter of the resistance-nodulation-cell division protein family. J. Biol. Chem. 274:26065-26070.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26065-26070
-
-
Goldberg, M.1
Pribyl, T.2
Juhnke, S.3
Nies, D.H.4
-
10
-
-
3042838743
-
Structure of the periplasmic component of a bacterial drug efflux pump
-
Higgins, M. K., E. Bokma, E. Koronakis, and V. Koronakis. 2004. Structure of the periplasmic component of a bacterial drug efflux pump. Proc. Natl. Acad. Sci. USA 101:9994-9999.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9994-9999
-
-
Higgins, M.K.1
Bokma, E.2
Koronakis, E.3
Koronakis, V.4
-
11
-
-
0346749468
-
H-induced changes in the conformation of AcrA, the membrane fusion protein of Escherichia coli multidrug efflux system
-
Ip, H., K. Stratton, H. Zgurskaya, and J. Liu. 2003. pH-induced changes in the conformation of AcrA, the membrane fusion protein of Escherichia coli multidrug efflux system. J. Biol. Chem. 278:50474-50482.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50474-50482
-
-
Ip, H.1
Stratton, K.2
Zgurskaya, H.3
Liu, J.4
-
12
-
-
0026437584
-
pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids
-
Kamp, F., and J. A. Hamilton. 1992. pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids. Proc. Natl. Acad. Sci. USA 89:11367-11370.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 11367-11370
-
-
Kamp, F.1
Hamilton, J.A.2
-
13
-
-
0028050605
-
Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: Active efflux as a contributing factor to β-lactam resistance
-
Li, X.-Z., D. Ma, D. M. Livermore, and H. Nikaido. 1994. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to β-lactam resistance. Antimicrob. Agents Chemother. 38:1742-1752.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 1742-1752
-
-
Li, X.-Z.1
Ma, D.2
Livermore, D.M.3
Nikaido, H.4
-
14
-
-
0028926676
-
Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli
-
Ma, D., D. N. Cook, M. Alberti, N. G. Pon, H. Nikaido, and J. E. Hearst. 1995. Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli. Mol. Microbiol. 16:45-55.
-
(1995)
Mol. Microbiol.
, vol.16
, pp. 45-55
-
-
Ma, D.1
Cook, D.N.2
Alberti, M.3
Pon, N.G.4
Nikaido, H.5
Hearst, J.E.6
-
15
-
-
0037057652
-
Crystal structure of bacterial multidrug efflux transporter AcrB
-
Murakami, S., R. Nakashima, E. Yamashita, and A. Yamaguchi. 2002. Crystal structure of bacterial multidrug efflux transporter AcrB. Nature 419:587-593.
-
(2002)
Nature
, vol.419
, pp. 587-593
-
-
Murakami, S.1
Nakashima, R.2
Yamashita, E.3
Yamaguchi, A.4
-
16
-
-
0029845913
-
Multidrug efflux pumps of gram-negative bacteria
-
Nikaido, H. 1996. Multidrug efflux pumps of gram-negative bacteria. J. Bacteriol. 178:5853-5859.
-
(1996)
J. Bacteriol.
, vol.178
, pp. 5853-5859
-
-
Nikaido, H.1
-
17
-
-
0031948133
-
Antibiotic resistance caused by Gram-negative multidrug efflux pumps
-
Nikaido, H. 1998. Antibiotic resistance caused by Gram-negative multidrug efflux pumps. Clin. Infect. Dis. 27(Suppl. 1):S32-S41.
-
(1998)
Clin. Infect. Dis.
, vol.27
, Issue.1 SUPPL.
-
-
Nikaido, H.1
-
18
-
-
0031720812
-
Multidrug efflux pump AcrAB of Salmonella typhimurium excretes only those β-lactam antibiotics containing lipophilic side chains
-
Nikaido, H., M. Basina, V. Nguyen, and E. Y. Rosenberg. 1998. Multidrug efflux pump AcrAB of Salmonella typhimurium excretes only those β-lactam antibiotics containing lipophilic side chains. J. Bacteriol. 180:4686-4692.
-
(1998)
J. Bacteriol.
, vol.180
, pp. 4686-4692
-
-
Nikaido, H.1
Basina, M.2
Nguyen, V.3
Rosenberg, E.Y.4
-
19
-
-
0032323640
-
Overview of bacterial ABC transporters
-
Nikaido, H., and J. A. Hall. 1998. Overview of bacterial ABC transporters. Methods Enzymol. 292:3-20.
-
(1998)
Methods Enzymol.
, vol.292
, pp. 3-20
-
-
Nikaido, H.1
Hall, J.A.2
-
20
-
-
0034817367
-
Analysis of a complete library of putative drug transporter genes in Escherichia coli
-
Nishino, K., and A. Yamaguchi. 2001. Analysis of a complete library of putative drug transporter genes in Escherichia coli. J. Bacteriol. 183:5803-5812.
-
(2001)
J. Bacteriol.
, vol.183
, pp. 5803-5812
-
-
Nishino, K.1
Yamaguchi, A.2
-
21
-
-
0030029513
-
AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants
-
Okusu, H., D. Ma, and H. Nikaido. 1996. AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants. J. Bacteriol. 178:306-308.
-
(1996)
J. Bacteriol.
, vol.178
, pp. 306-308
-
-
Okusu, H.1
Ma, D.2
Nikaido, H.3
-
22
-
-
0034090541
-
AcrD of Escherichia coli is an aminoglycoside efflux pump
-
Rosenberg, E. Y., D. Ma, and H. Nikaido. 2000. AcrD of Escherichia coli is an aminoglycoside efflux pump. J. Bacteriol. 182:1754-1756.
-
(2000)
J. Bacteriol.
, vol.182
, pp. 1754-1756
-
-
Rosenberg, E.Y.1
Ma, D.2
Nikaido, H.3
-
23
-
-
0023867105
-
Porin channels in intact cells of Escherichia coli are not affected by Donnan potential across the outer membrane
-
Sen, K., J. Hellman, and H. Nikaido. 1988. Porin channels in intact cells of Escherichia coli are not affected by Donnan potential across the outer membrane. J. Biol. Chem. 263:1182-1187.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 1182-1187
-
-
Sen, K.1
Hellman, J.2
Nikaido, H.3
-
24
-
-
0028321391
-
OmpA protein of Escherichia coli outer membrane occurs in open and closed channel forms
-
Sugawara, E., and H. Nikaido. 1994. OmpA protein of Escherichia coli outer membrane occurs in open and closed channel forms. J. Biol. Chem. 269:17981-17987.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17981-17987
-
-
Sugawara, E.1
Nikaido, H.2
-
25
-
-
0035086501
-
Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes
-
Sulavik, M. C., C. Houseweart, C. Cramer, N. Jiwani, N. Murgolo, J. Greeene, B. DiDomenico, K. J. Shaw, G. H. Miller, R. Hare, and G. Shimer. 2001. Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes. Antimicrob. Agents Chemother. 45:1126-1136.
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 1126-1136
-
-
Sulavik, M.C.1
Houseweart, C.2
Cramer, C.3
Jiwani, N.4
Murgolo, N.5
Greeene, J.6
DiDomenico, B.7
Shaw, K.J.8
Miller, G.H.9
Hare, R.10
Shimer, G.11
-
26
-
-
0033170990
-
The RND permease superfamily: An ancient, ubiquitous and diverse family that includes human disease and development proteins
-
Tseng, T. T., K. S. Gratwick, J. Kollman, D. Park, D. H. Nies, A. Goffeau, and M. H. Saier, Jr. 1999. The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins. J. Mol. Microbiol. Biotechnol. 1:107-125.
-
(1999)
J. Mol. Microbiol. Biotechnol.
, vol.1
, pp. 107-125
-
-
Tseng, T.T.1
Gratwick, K.S.2
Kollman, J.3
Park, D.4
Nies, D.H.5
Goffeau, A.6
Saier Jr., M.H.7
-
27
-
-
0141615783
-
AcrB multidrug efflux pump of Escherichia coli: Composite substrate-binding cavity of exceptional flexibility generates its extremely wide substrate specificity
-
Yu, E. W., J. R. Aires, and H. Nikaido. 2003. AcrB multidrug efflux pump of Escherichia coli: composite substrate-binding cavity of exceptional flexibility generates its extremely wide substrate specificity. J. Bacteriol. 185:5657-5664.
-
(2003)
J. Bacteriol.
, vol.185
, pp. 5657-5664
-
-
Yu, E.W.1
Aires, J.R.2
Nikaido, H.3
-
28
-
-
0038670226
-
Structural basis of multiple drug-binding capacity of AcrB multidrug efflux pump
-
Yu, E. W., G. McDermott, H. I. Zgurskaya, H. Nikaido, and D. E. Koshland, Jr. 2003. Structural basis of multiple drug-binding capacity of AcrB multidrug efflux pump. Science 300:976-980.
-
(2003)
Science
, vol.300
, pp. 976-980
-
-
Yu, E.W.1
McDermott, G.2
Zgurskaya, H.I.3
Nikaido, H.4
Koshland Jr., D.E.5
-
29
-
-
0033594886
-
Bypassing the periplasm: Reconstitution of the AcrAB multidrug efflux pump of Escherichia coli
-
Zgurskaya, H. I., and H. Nikaido. 1999. Bypassing the periplasm: reconstitution of the AcrAB multidrug efflux pump of Escherichia coli. Proc. Natl. Acad. Sci. USA 96:7190-7195.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7190-7195
-
-
Zgurskaya, H.I.1
Nikaido, H.2
-
30
-
-
0033534373
-
AcrA is a highly asymmetric protein capable of spanning the periplasm
-
Zgurskaya, H. I., and H. Nikaido. 1999. AcrA is a highly asymmetric protein capable of spanning the periplasm. J. Mol. Biol. 285:409-420.
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 409-420
-
-
Zgurskaya, H.I.1
Nikaido, H.2
-
31
-
-
0033912430
-
Multidrug resistance mechanisms: Drug efflux across two membranes
-
Zgurskaya, H. I., and H. Nikaido. 2000. Multidrug resistance mechanisms: drug efflux across two membranes. Mol. Microbiol. 37:219-235.
-
(2000)
Mol. Microbiol.
, vol.37
, pp. 219-235
-
-
Zgurskaya, H.I.1
Nikaido, H.2
-
32
-
-
0033940002
-
Cross-linked complex between oligomeric periplasmic lipoprotein AcrA and the inner-membrane-associated multidrug efflux pump AcrB from Escherichia coli
-
Zgurskaya, H. I., and H. Nikaido. 2000. Cross-linked complex between oligomeric periplasmic lipoprotein AcrA and the inner-membrane-associated multidrug efflux pump AcrB from Escherichia coli. J. Bacteriol. 182:4264-4267.
-
(2000)
J. Bacteriol.
, vol.182
, pp. 4264-4267
-
-
Zgurskaya, H.I.1
Nikaido, H.2
|