Crystal structure of the multidrug efflux transporter AcrB at 3.1 Å resolution reveals the N-terminal region with conserved amino acids

Journal of Structural Biology

Volumn 158, Issue 3, 2007, Pages 494-502

  Das, Debanu ^a,b   Xu, Qian Steven ^a   Lee, Jonas Y ^a,b   Ankoudinova, Irina ^a   Huang, Candice ^a,c   Lou, Yun ^a   DeGiovanni, Andy ^a   Kim, Rosalind ^a   Kim, Sung Hou ^a,b  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BIO RAD LABORATORIES   (United States)

Author keywords

AcrB; Crystal structure; Membrane protein; Multidrug efflux transporter; N terminal loop with conserved amino acids

Indexed keywords

AMINO ACID; GLYCOPROTEIN P; MEMBRANE PROTEIN; MULTIDRUG TRANSPORTER ACRB; PHENYLALANINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; CYTOPLASM; DRUG UPTAKE; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN STRUCTURE; X RAY DIFFRACTION;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT; CONSERVED SEQUENCE; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; CYTOSOL; MOLECULAR SEQUENCE DATA; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PHARMACEUTICAL PREPARATIONS; PROTEIN CONFORMATION;

BACTERIA (MICROORGANISMS);

EID: 34248572735     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2006.12.004     Document Type: Article

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