Allosteric modulation of caspase 3 through mutagenesis

Bioscience Reports

Volumn 32, Issue 4, 2012, Pages 401-411

  Walters, Jad ^a   Schipper, Joshua L ^a   Swartz, Paul ^a   Mattos, Carla ^a,b   Clark, A Clay ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Allosteric site; Apoptosis; Caspase; Inhibition; Protein ensemble

Indexed keywords

CASPASE 3;

ALLOSTERISM; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SUBSTRATE COMPLEX; MOLECULAR DYNAMICS; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; STRUCTURE ANALYSIS; SURFACE PROPERTY; X RAY CRYSTALLOGRAPHY;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; AMINO ACID SUBSTITUTION; CASPASE 3; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, SECONDARY;

EID: 84863667542     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20120037     Document Type: Article

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