An Uncleavable Procaspase-3 Mutant Has a Lower Catalytic Efficiency but an Active Site Similar to That of Mature Caspase-3

Biochemistry

Volumn 42, Issue 42, 2003, Pages 12298-12310

  Bose, Kakoli ^a   Pop, Cristina ^a   Feeney, Brett ^a   Clark, A Clay ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ENZYMES; FLUORESCENCE; PH EFFECTS; QUENCHING;

MUTANTS;

BIOCHEMISTRY;

AMINO ACID; CASPASE 3; ENZYME PRECURSOR; PROCASPASE 3; PROTEINASE; SOLVENT; TRYPSIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE; NONHUMAN; PH; PKA; PRIORITY JOURNAL; PROTEIN DEGRADATION;

BASE SEQUENCE; BINDING SITES; CASPASE 3; CASPASES; CATALYSIS; DNA PRIMERS; ENZYME ACTIVATION; ENZYME PRECURSORS; FLUORESCENCE; HYDROLYSIS; MODELS, MOLECULAR; PROTEIN CONFORMATION; TRYPSIN;

EID: 0142063422     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034998x     Document Type: Article

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