Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3

Archives of Biochemistry and Biophysics

Volumn 508, Issue 1, 2011, Pages 31-38

  Walters, Jad ^a   Swartz, Paul ^a   Mattos, Carla ^a   Clark, A Clay ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Caspase activation; Enzyme activity; Protein folding and assembly

Indexed keywords

CASPASE 3;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME STRUCTURE; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION;

CASPASE 3; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME STABILITY; HYDROGEN BONDING; MODELS, MOLECULAR; MUTATION; PROTEIN FOLDING; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 79952452195     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2011.01.011     Document Type: Article

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