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Volumn 8, Issue 2, 2008, Pages 98-109
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Targeting cell death in tumors by activating caspases
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Author keywords
Active site formation; Active site loops; Apoptosis; Cancer treatment; Caspase; Crystallography; Dimer interface; Dimerization; Enzyme activation; Human disease; Programmed cell death; Protease; Proteolytic cleavage; Zymogen
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Indexed keywords
BLEOMYCIN;
CASPASE;
CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN;
CYCLIN DEPENDENT KINASE INHIBITOR;
CYCLOPHOSPHAMIDE;
CYTOTOXIC AGENT;
DACARBAZINE;
DIMER;
DOXORUBICIN;
ENZYME PRECURSOR;
ETOPOSIDE;
FLAVOPIRIDOL;
HISTIDINE;
METHOTREXATE;
PACLITAXEL;
PREDNISONE;
PROCARBAZINE;
PROCASPASE 3;
PURVANOLOL A;
UNCLASSIFIED DRUG;
VALINE;
VINBLASTINE;
X LINKED INHIBITOR OF APOPTOSIS;
APOPTOSIS;
BIOCHEMISTRY;
BIOPHYSICS;
CANCER CELL;
CANCER THERAPY;
CELL DEATH;
CELL KILLING;
CELL STRUCTURE;
CYTOLOGY;
DRUG TARGETING;
ENZYME ACTIVATION;
ENZYME ACTIVE SITE;
ENZYME BINDING;
HUMAN;
MEDICAL RESEARCH;
MUTANT;
NONHUMAN;
REVIEW;
SIGNAL TRANSDUCTION;
STIMULUS;
TARGET CELL;
TUMOR;
TUMOR CELL;
TUMOR RESISTANCE;
AMINO ACID SEQUENCE;
ANIMALS;
ANTINEOPLASTIC AGENTS;
CASPASES;
CELL DEATH;
DRUG DELIVERY SYSTEMS;
ENZYME ACTIVATION;
HUMANS;
MOLECULAR SEQUENCE DATA;
NEOPLASMS;
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EID: 40449141956
PISSN: 15680096
EISSN: None
Source Type: Journal
DOI: 10.2174/156800908783769391 Document Type: Review |
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Times cited : (87)
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References (109)
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