Chronic administration of the selective P2X3, P2X2/3 receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice

European Journal of Pharmacology

Volumn 688, Issue 1-3, 2012, Pages 27-34

  Hansen, Rikke Rie ^a   Nasser, Arafat ^a   Falk, Sarah ^a   Baldvinsson, Signe B ^a   Ohlsson, Pernille H ^a   Bahl, Justyna M C ^b   Jarvis, Michael F ^c   Ding, Ming ^d   Heegaard, Anne Marie ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b STATENS SERUM INSTITUT   (Denmark)

^c ABBOTT LABORATORIES   (United States)

^d ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

A 317491 (5 (3 Phenoxyphenyl)methyl (1S) 1,2,3,4 tetrahydro 1 naphthalenyl amino carbonyl 1,2,4 benzenetricarboxylic acid sodium salt hydrate); Bone cancer pain; P2X2 3 receptor; P2X3 receptor

Indexed keywords

5 [[(3 PHENOXYBENZYL)(1,2,3,4 TETRAHYDRO 1 NAPHTHYL)AMINO]CARBONYL]TRIMELLITIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE CANCER; BONE PAIN; CANCER PAIN; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG SELECTIVITY; FEMUR; LONG TERM CARE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTEMIC THERAPY;

ANIMALS; BONE NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; CLONE CELLS; MALE; MICE; PAIN; PHENOLS; POLYCYCLIC COMPOUNDS; PURINERGIC P2X RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2X2; RECEPTORS, PURINERGIC P2X3; TIME FACTORS;

EID: 84863533721     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.05.008     Document Type: Article

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