Peripheral mechanisms underlying the essential role of P2X3,2/3 receptors in the development of inflammatory hyperalgesia

Pain

Volumn 141, Issue 1-2, 2009, Pages 127-134

  Oliveira, Maria Cláudia G ^a   Pelegrini da Silva, Adriana ^a   Tambeli, Cláudia Herrera ^a   Parada, Carlos Amílcar ^b  

^a Piracicaba Dental School   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Antisense; ATP; Carrageenan; Cytokines; Mechanical inflammatory hyperalgesia; Neutrophils; P2X3,2 3 receptors

Indexed keywords

5 [[(3 PHENOXYBENZYL)(1,2,3,4 TETRAHYDRO 1 NAPHTHYL)AMINO]CARBONYL]TRIMELLITIC ACID; ADENOSINE TRIPHOSPHATE; ANTISENSE OLIGONUCLEOTIDE; CARRAGEENAN; COMPLEMENTARY DNA; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; INTERLEUKIN 1BETA; MYELOPEROXIDASE; PURINERGIC P2X RECEPTOR; PURINERGIC P2X3 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CYTOKINE PRODUCTION; DNA SEQUENCE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPERALGESIA; INFLAMMATION; LEUKOCYTE MIGRATION; MALE; NEUTROPHIL; NOCICEPTIVE RECEPTOR; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SAPHENOUS NERVE; SENSITIZATION; WESTERN BLOTTING; WISTAR ALBINO GLAXO RAT;

ADENOSINE TRIPHOSPHATE; ANALYSIS OF VARIANCE; ANIMALS; CARRAGEENAN; CYTOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPERALGESIA; INFLAMMATION; MALE; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PAIN MEASUREMENT; PAIN THRESHOLD; PEROXIDASE; PHENOLS; POLYCYCLIC COMPOUNDS; POLYSACCHARIDES; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; TIME FACTORS;

EID: 58149173964     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2008.10.024     Document Type: Article

References (36)

1. Barclay J., Patel S., Dorn G., Wotherspoon G., Moffatt S., Eunson L., et al. Functional downregulation of P2X3 receptor subunit in rat sensory neurons reveals a significant role in chronic neuropathic and inflammatory pain. J Neurosci 22 (2002) 8139-8147
2. Bradley P.P., Priebat D.A., Christensen R.D., and Rothstein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78 (1982) 206-209
3. Chen C.C., Akopian A.N., Sivilotti L., Colquhoun D., Burnstock G., and Wood J.N. A P2X purinoceptor expressed by a subset of sensory neurons. Nature 377 (1995) 428-431
4. Cockayne D.A., Dunn P.M., Zhong Y., Rong W., Hamilton S.G., Knight G.E., et al. P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP. J Physiol 567 (2005) 621-639
5. Cunha F.Q., Lorenzetti B.B., Poole S., and Ferreira S.H. Interleukin-8 as a mediator of sympathetic pain. Br J Pharmacol 104 (1991) 765-767
6. Cunha F.Q., Poole S., Lorenzetti B.B., and Ferreira S.H. The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia. Br J Pharmacol 107 (1992) 660-664
7. Cunha T.M., Verri Jr. W.A., Schivo I.R., Napimoga M.H., Parada C.A., Poole S., et al. Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. J Leukoc Biol 83 (2008) 824-832
8. Ferreira S.H., Lorenzetti B.B., Cunha F.Q., and Poole S. Bradykinin release of TNF-alpha plays a key role in the development of inflammatory hyperalgesia. Agents Actions 38 (1993) Spec. No. C7-9
9. Ferreira S.H., Lorenzetti B.B., and Poole S. Bradykinin initiates cytokine-mediated inflammatory hyperalgesia. Br J Pharmacol 110 (1993) 1227-1231
10. Ferreira S.H., Moncada S., Parsons M., and Vane J.R. Proceedings: the concomitant release of bradykinin and prostaglandin in the inflammatory response to carrageenin. Br J Pharmacol 52 (1974) 108P-109P
11. Fukui M., Nakagawa T., Minami M., Satoh M., and Kaneko S. Inhibitory role of supraspinal P2X3/P2X2/3 subtypes on nociception in rats. Mol Pain 2 (2006) 19
12. Gold M.S., Shuster M.J., and Levine J.D. Role of a Ca(2+)-dependent slow after hyperpolarization in prostaglandin E2-induced sensitization of cultured rat sensory neurons. Neurosci Lett 205 (1996) 161-164
13. Honore P., Kage K., Mikusa J., Watt A.T., Johnston J.F., Wyatt J.R., et al. Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats. Pain 99 (2002) 11-19
14. Jarvis M.F., Burgard E.C., McGaraughty S., Honore P., Lynch K., Brennan T.J., et al. A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Proc Natl Acad Sci USA 99 (2002) 17179-17184
15. Jarvis M.F., Wismer C.T., Schweitzer E., Yu H., van Biesen T., Lynch K.J., et al. Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP-ATP and enhancement by the P2X(3) allosteric modulator, cibacron blue. Br J Pharmacol 132 (2001) 259-269
16. Kennedy C., Assis T.S., Currie A.J., and Rowan E.G. Crossing the pain barrier: P2 receptors as targets for novel analgesics. J Physiol 553 (2003) 683-694
17. Kennedy C., and Leff P. Painful connection for ATP. Nature 377 (1995) 385-386
18. Le Bars D., Dickenson A.H., and Besson J.M. Diffuse noxious inhibitory controls (DNIC) I. Effects on dorsal horn convergent neurones in the rat. Pain 6 (1979) 283-304
19. Lewis C., Neidhart S., Holy C., North R.A., Buell G., and Surprenant A. Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons. Nature 377 (1995) 432-435
20. Loram L.C., Fuller A., Fick L.G., Cartmell T., Poole S., and Mitchell D. Cytokine profiles during carrageenan-induced inflammatory hyperalgesia in rat muscle and hind paw. J Pain 8 (2007) 127-136
21. Lorenzetti B.B., Veiga F.H., Canetti C.A., Poole S., Cunha F.Q., and Ferreira S.H. Cytokine-induced neutrophil chemoattractant 1 (CINC-1) mediates the sympathetic component of inflammatory mechanical hypersensitivity in rats. **Eur Cytokine Netw 13 (2002) 456-461
22. McGaraughty S., Honore P., Wismer C.T., Mikusa J., Zhu C.Z., McDonald H.A., et al. Endogenous opioid mechanisms partially mediate P2X3/P2X2/3-related antinociception in rat models of inflammatory and chemogenic pain but not neuropathic pain. Br J Pharmacol 146 (2005) 180-188
23. McGaraughty S., Wismer C.T., Zhu C.Z., Mikusa J., Honore P., Chu K.L., et al. Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration. Br J Pharmacol 140 (2003) 1381-1388
24. Moncada S., Ferreira S.H., and Vane J.R. Prostaglandins, aspirin-like drugs and the oedema of inflammation. Nature 246 (1973) 217-219
25. Oliveira M.C., Pelegrini-da-Silva A., Parada C.A., and Tambeli C.H. 5-HT acts on nociceptive primary afferents through an indirect mechanism to induce hyperalgesia in the subcutaneous tissue. Neuroscience 145 (2007) 708-714
26. Papir-Kricheli D., Frey J., Laufer R., Gilon C., Chorev M., Selinger Z., et al. Behavioural effects of receptor-specific substance P agonists. Pain 31 (1987) 263-276
27. Parada C.A., Yeh J.J., Joseph E.K., and Levine J.D. Tumor necrosis factor receptor type-1 in sensory neurons contributes to induction of chronic enhancement of inflammatory hyperalgesia in rat. Eur J Neurosci 17 (2003) 1847-1852
28. Randall L.O., and Selitto J.J. A method for measurement of analgesic activity on inflamed tissue. Arch Int Pharmacodyn Ther 111 (1957) 409-419
29. Rosland J.H. The formalin test in mice: the influence of ambient temperature. Pain 45 (1991) 211-216
30. Rush A.M., and Waxman S.G. PGE2 increases the tetrodotoxin-resistant Nav1 9 sodium current in mouse DRG neurons via G-proteins. Brain Res 1023 (2004) 264-271
31. Safieh-Garabedian B., Poole S., Allchorne A., Winter J., and Woolf C.J. Contribution of interleukin-1 beta to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br J Pharmacol 115 (1995) 1265-1275
32. Sharp C.J., Reeve A.J., Collins S.D., Martindale J.C., Summerfield S.G., Sargent B.S., et al. Investigation into the role of P2X(3)/P2X(2/3) receptors in neuropathic pain following chronic constriction injury in the rat: an electrophysiological study. Br J Pharmacol 148 (2006) 845-852
33. Shinoda M., Ozaki N., Asai H., Nagamine K., and Sugiura Y. Changes in P2X3 receptor expression in the trigeminal ganglion following monoarthritis of the temporomandibular joint in rats. Pain 116 (2005) 42-51
34. Wu G., Whiteside G.T., Lee G., Nolan S., Niosi M., Pearson M.S., et al. A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats. Eur J Pharmacol 504 (2004) 45-53
35. Zhang X.W., Liu Q., and Thorlacius H. Inhibition of selectin function and leukocyte rolling protects against dextran sodium sulfate-induced murine colitis. Scand J Gastroenterol 36 (2001) 270-275
36. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16 (1983) 109-110