메뉴 건너뛰기




Volumn 32, Issue 7, 2012, Pages 1277-1309

Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain

Author keywords

Blood flow; cranial window; neurovascular coupling; stroke; two photon microscopy; vasculature

Indexed keywords

ARTERIOLE; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; CELL ACTIVITY; ELECTRICAL EQUIPMENT; ELECTROCORTICOGRAPHY; LASER MICROSCOPY; MEASUREMENT; MOUSE; NEUROIMAGING; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; SMOOTH MUSCLE; SURGICAL EQUIPMENT; SURGICAL TECHNIQUE; TWO PHOTON LASER SCANNING MICROSCOPY;

EID: 84863446808     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2011.196     Document Type: Review
Times cited : (361)

References (212)
  • 2
    • 77955171581 scopus 로고    scopus 로고
    • Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins
    • Akemann W, Mutoh H, Perron A, Rossier J, Knopfel T (2010) Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins. Nat Methods 7:643-9
    • (2010) Nat Methods , vol.7 , pp. 643-649
    • Akemann, W.1    Mutoh, H.2    Perron, A.3    Rossier, J.4    Knopfel, T.5
  • 4
    • 0033378522 scopus 로고    scopus 로고
    • Laser doppler imaging of activation-flow coupling in the rat somatosensory cortex
    • Ances BM, Greenberg JH, Detre JA (1999) Laser doppler imaging of activation-flow coupling in the rat somatosensory cortex. Neuroimage 10:25-8
    • (1999) Neuroimage , vol.10 , pp. 25-28
    • Ances, B.M.1    Greenberg, J.H.2    Detre, J.A.3
  • 7
    • 19444382379 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II by RNA interference
    • DOI 10.1016/j.ymthe.2005.02.016, PII S1525001605000869
    • Babcock AM, Standing D, Bullshields K, Schwartz E, Paden CM, Poulsen DJ (2005) in vivo inhibition of hippocampal Ca2 +calmodulin-dependent protein kinase II by RNA interference. Mol Ther 11:899-905 (Pubitemid 40724108)
    • (2005) Molecular Therapy , vol.11 , Issue.6 , pp. 899-905
    • Babcock, A.M.1    Standing, D.2    Bullshields, K.3    Schwartz, E.4    Paden, C.M.5    Poulsen, D.J.6
  • 8
    • 0018847124 scopus 로고
    • The vascular system of the cerebral cortex
    • Bar T (1980) The vascular system of the cerebral cortex. Adv Anat Embryol Cell Biol 59:1-62
    • (1980) Adv Anat Embryol Cell Biol , vol.59 , pp. 1-62
    • Bar, T.1
  • 9
    • 67649610690 scopus 로고    scopus 로고
    • In vivo fluorescence imaging with high-resolution microlenses
    • Barretto RP, Messerschmidt B, Schnitzer MJ (2009) In vivo fluorescence imaging with high-resolution microlenses. Nat Methods 6:511-2
    • (2009) Nat Methods , vol.6 , pp. 511-512
    • Barretto, R.P.1    Messerschmidt, B.2    Schnitzer, M.J.3
  • 10
    • 77955438276 scopus 로고    scopus 로고
    • Topological basis for the robust distribution of blood to rodent neocortex
    • Blinder P, Shih AY, Rafie CA, Kleinfeld D (2010) Topological basis for the robust distribution of blood to rodent neocortex. Proc Natl Acad Sci USA 107:12670-5
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 12670-12675
    • Blinder, P.1    Shih, A.Y.2    Rafie, C.A.3    Kleinfeld, D.4
  • 11
    • 26444621497 scopus 로고    scopus 로고
    • Millisecond-timescale, genetically targeted optical control of neural activity
    • DOI 10.1038/nn1525, PII N1525
    • Boyden ES, Zhang F, Bamberg E, Nagel G, Deisseroth K (2005) Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci 8:1263-8 (Pubitemid 43348147)
    • (2005) Nature Neuroscience , vol.8 , Issue.9 , pp. 1263-1268
    • Boyden, E.S.1    Zhang, F.2    Bamberg, E.3    Nagel, G.4    Deisseroth, K.5
  • 12
    • 34247151722 scopus 로고    scopus 로고
    • Extensive turnover of dendritic spines and vascular remodeling in cortical tissues recovering from stroke
    • DOI 10.1523/JNEUROSCI.4295-06.2007
    • Brown CE, Li P, Boyd JD, Delaney KR, Murphy TH (2007) Extensive turnover of dendritic spines and vascular remodeling in cortical tissues recovering from stroke. J Neurosci 27:4101-9 (Pubitemid 46597152)
    • (2007) Journal of Neuroscience , vol.27 , Issue.15 , pp. 4101-4109
    • Brown, C.E.1    Li, P.2    Boyd, J.D.3    Delaney, K.R.4    Murphy, T.H.5
  • 13
    • 0347671203 scopus 로고    scopus 로고
    • Telemetric measurement of cardiovascular parameters
    • Butz GM, Davisson RL (2001) telemetric measurement of cardiovascular parameters. Physiol Genomics 5:89-97
    • (2001) Physiol Genomics , vol.5 , pp. 89-97
    • Butz, G.M.1    Davisson, R.L.2
  • 14
    • 0031809018 scopus 로고    scopus 로고
    • Dynamics of blood flow and oxygenation changes during brain activation: The balloon model
    • DOI 10.1002/mrm.1910390602
    • Buxton RB, Wong EC, Frank LR (1998) Dynamics of blood flow and oxygenation changes during brain activation: the balloon model. Magn Reson Med 39:855-64 (Pubitemid 28237743)
    • (1998) Magnetic Resonance in Medicine , vol.39 , Issue.6 , pp. 855-864
    • Buxton, R.B.1    Wong, E.C.2    Frank, L.R.3
  • 16
    • 5644289368 scopus 로고    scopus 로고
    • Cortical GABA interneurons in neurovascular coupling: Relays for subcortical vasoactive pathways
    • DOI 10.1523/JNEUROSCI.3065-04.2004
    • Cauli B, Tong XK, Rancillac A, Serluca N, Lambolez B, Rossier J, Hamel E (2004) Cortical GABA interneurons in neurovascular coupling: relays for subcortical vasoactive pathways. J Neurosci 24:8940-9 (Pubitemid 39372239)
    • (2004) Journal of Neuroscience , vol.24 , Issue.41 , pp. 8940-8949
    • Cauli, B.1    Tong, X.-K.2    Rancillac, A.3    Serluca, N.4    Lambolez, B.5    Rossier, J.6    Hamel, E.7
  • 19
    • 34250304323 scopus 로고    scopus 로고
    • The relationship between blood flow and neuronal activity in the rodent olfactory bulb
    • DOI 10.1523/JNEUROSCI.3141-06.2007
    • Chaigneau E, Tiret P, Lecoq J, Ducros M, Knöpfel T, Charpak S (2007) The relationship between blood flow and neuronal activity in the rodent olfactory bulb. J Neurosci 27:6452-60 (Pubitemid 46920368)
    • (2007) Journal of Neuroscience , vol.27 , Issue.24 , pp. 6452-6460
    • Chaigneau, E.1    Tiret, P.2    Lecoq, J.3    Ducros, M.4    Knopfel, T.5    Charpak, S.6
  • 20
    • 7444250117 scopus 로고    scopus 로고
    • Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period
    • Chattopadhyaya B, Cristo GD, Higashiyama H, Knott GW, Kuhlman SJ, Welker E, Huang ZJ (2004) Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period. J Neurosci 24:9498-611
    • (2004) J Neurosci , vol.24 , pp. 9498-9611
    • Chattopadhyaya, B.1    Cristo, G.D.2    Higashiyama, H.3    Knott, G.W.4    Kuhlman, S.J.5    Welker, E.6    Huang, Z.J.7
  • 22
    • 79551526438 scopus 로고    scopus 로고
    • Simultaneous two-photon calcium imaging at different depths with spatiotemporal multiplexing
    • Cheng A, Goncalves JT, Golshani P, Arisaka K, Portera-Cailliau C (2011) Simultaneous two-photon calcium imaging at different depths with spatiotemporal multiplexing. Nat Methods 8:139-42
    • (2011) Nat Methods , vol.8 , pp. 139-142
    • Cheng, A.1    Goncalves, J.T.2    Golshani, P.3    Arisaka, K.4    Portera-Cailliau, C.5
  • 24
    • 34247148660 scopus 로고    scopus 로고
    • High-resolution in vivo imaging of the neurovascular unit during spreading depression
    • DOI 10.1523/JNEUROSCI.0721-07.2007
    • Chuquet J, Hollender L, Nimchinsky EA (2007) Highresolution in vivo imaging of the neurovascular unit during spreading depression. J Neurosci 27:4036-44 (Pubitemid 46597148)
    • (2007) Journal of Neuroscience , vol.27 , Issue.15 , pp. 4036-4044
    • Chuquet, J.1    Hollender, L.2    Nimchinsky, E.A.3
  • 25
    • 0022608311 scopus 로고
    • Transoral tracheal intubation of rodents using a fiberoptic laryngoscope
    • Costa DL, Lehmann JR, Harold WM, Drew RT (1986) Transoral tracheal intubation of rodents using a fiberoptic laryngoscope. Lab Anim Sci 36:256-61 (Pubitemid 16098705)
    • (1986) Laboratory Animal Science , vol.36 , Issue.3 , pp. 256-261
    • Costa, D.L.1    Lehmann, J.R.2    Harold, W.M.3    Drew, R.T.4
  • 26
    • 0034888287 scopus 로고    scopus 로고
    • Applications of the Morris water maze in the study of learning and memory
    • DOI 10.1016/S0165-0173(01)00067-4, PII S0165017301000674
    • D'Hooge R, De Deyn PP (2001) Applications of the Morris water maze in the study of learning and memory. Brain Res Brain Res Rev 36:60-90 (Pubitemid 32763130)
    • (2001) Brain Research Reviews , vol.36 , Issue.1 , pp. 60-90
    • D'Hooge, R.1    De Deyn, P.P.2
  • 27
    • 0029018863 scopus 로고
    • Cerebrovascular responses under controlled and monitored physiological conditions in the anesthetized mouse
    • Dalkara T, Irikura K, Huang Z, Panahian N, Moskowitz MA (1995) Cerebrovascular responses under controlled and monitored physiological conditions in the anesthetized mouse. J Cereb Blood Flow Metab 15:631-8
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 631-638
    • Dalkara, T.1    Irikura, K.2    Huang, Z.3    Panahian, N.4    Moskowitz, M.A.5
  • 31
    • 0025342635 scopus 로고
    • Two-photon laser scanning fluorescence microscopy
    • Denk W, Strickler JH, Webb WW (1990) Two-photon laser scanning fluorescence microscopy. Science 248:73-6
    • (1990) Science , vol.248 , pp. 73-76
    • Denk, W.1    Strickler, J.H.2    Webb, W.W.3
  • 32
    • 0037659201 scopus 로고    scopus 로고
    • Imaging spatiotemporal dynamics of surround inhibition in the barrels somatosensory cortex
    • Derdikman D, Hildesheim R, Ahissar E, Arieli A, Grinvald A (2003) Imaging spatiotemporal dynamics of surround inhibition in the barrels somatosensory cortex. J Neurosci 23:3100-5 (Pubitemid 36531949)
    • (2003) Journal of Neuroscience , vol.23 , Issue.8 , pp. 3100-3105
    • Derdikman, D.1    Hildesheim, R.2    Ahissar, E.3    Arieli, A.4    Grinvald, A.5
  • 36
  • 37
    • 70449382583 scopus 로고    scopus 로고
    • Functional clustering of neurons in motor cortex determined by cellular resolution imaging in awake behaving mice
    • Dombeck DA, Graziano MS, Tank DW (2009) Functional clustering of neurons in motor cortex determined by cellular resolution imaging in awake behaving mice. J Neurosci 29:13751-60
    • (2009) J Neurosci , vol.29 , pp. 13751-13756
    • Dombeck, D.A.1    Graziano, M.S.2    Tank, D.W.3
  • 38
    • 78049299090 scopus 로고    scopus 로고
    • Functional imaging of hippocampal place cells at cellular resolution during virtual navigation
    • Dombeck DA, Harvey CD, Tian L, Looger LL, Tank DW (2010) Functional imaging of hippocampal place cells at cellular resolution during virtual navigation. Nat Neurosci 13:1433-40
    • (2010) Nat Neurosci , vol.13 , pp. 1433-1440
    • Dombeck, D.A.1    Harvey, C.D.2    Tian, L.3    Looger, L.L.4    Tank, D.W.5
  • 39
    • 34748867201 scopus 로고    scopus 로고
    • Imaging Large-Scale Neural Activity with Cellular Resolution in Awake, Mobile Mice
    • DOI 10.1016/j.neuron.2007.08.003, PII S0896627307006149
    • Dombeck DA, Khabbaz AN, Collman F, Adelman TL, Tank DW (2007) Imaging large-scale neural activity with cellular resolution in awake, mobile mice. Neuron 56:43-57 (Pubitemid 47484173)
    • (2007) Neuron , vol.56 , Issue.1 , pp. 43-57
    • Dombeck, D.A.1    Khabbaz, A.N.2    Collman, F.3    Adelman, T.L.4    Tank, D.W.5
  • 41
    • 77955170921 scopus 로고    scopus 로고
    • Rapid determination of particle velocity from space-time images using the Radon transform
    • Drew PJ, Blinder P, Cauwenberghs G, Shih AY, Kleinfeld D (2010a) Rapid determination of particle velocity from space-time images using the Radon transform. J Comput Neurosci 29:5-11
    • (2010) J Comput Neurosci , vol.29 , pp. 5-11
    • Drew, P.J.1    Blinder, P.2    Cauwenberghs, G.3    Shih, A.Y.4    Kleinfeld, D.5
  • 43
    • 79957698081 scopus 로고    scopus 로고
    • Fluctuating and sensory-induced vasodynamics in rodent cortex extends arteriole capacity
    • Drew PJ, Shih AY, Kleinfeld D (2011) Fluctuating and sensory-induced vasodynamics in rodent cortex extends arteriole capacity. Proc Natl Acad Sci USA 108: 8473-8
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 8473-8478
    • Drew, P.J.1    Shih, A.Y.2    Kleinfeld, D.3
  • 44
    • 84859260344 scopus 로고    scopus 로고
    • Quantitative two-photon imaging of blood flow in cortex
    • (Yuste R, ed), New York: Cold Spring Harbor Laboratory Press
    • Driscoll JD, Shih AY, Drew PJ, Kleinfeld D (2011a) Quantitative two-photon imaging of blood flow in cortex. In: Imaging in neuroscience and development Vol. 2 (Yuste R, ed), New York: Cold Spring Harbor Laboratory Press, 927-37
    • (2011) Imaging in Neuroscience and Development , vol.2 , pp. 927-937
    • Driscoll, J.D.1    Shih, A.Y.2    Drew, P.J.3    Kleinfeld, D.4
  • 47
    • 79952490984 scopus 로고    scopus 로고
    • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression
    • Eikermann-Haerter K, Yuzawa I, Dilekoz E, Joutel A, Moskowitz MA, Ayata C (2011) Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression. Ann Neurol 69:413-8
    • (2011) Ann Neurol , vol.69 , pp. 413-418
    • Eikermann-Haerter, K.1    Yuzawa, I.2    Dilekoz, E.3    Joutel, A.4    Moskowitz, M.A.5    Ayata, C.6
  • 49
    • 78650645093 scopus 로고    scopus 로고
    • Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain
    • Fernández-Klett F, Offenhauser N, Dirnagl U, Priller J, Lindauer U (2010) Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain. Proc Natl Acad Sci USA 107: 22290-5
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 22290-22295
    • Fernández-Klett, F.1    Offenhauser, N.2    Dirnagl, U.3    Priller, J.4    Lindauer, U.5
  • 50
    • 34248545253 scopus 로고    scopus 로고
    • Selective Stimulation of Astrocyte Calcium In Situ Does Not Affect Neuronal Excitatory Synaptic Activity
    • DOI 10.1016/j.neuron.2007.04.032, PII S0896627307003364
    • Fiacco TA, Agulhon C, Taves SR, Petravicz J, Caspar KB, Dong X, Chen J, McCarthy KD (2007) Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity. Neuron 54:611-26 (Pubitemid 46756143)
    • (2007) Neuron , vol.54 , Issue.4 , pp. 611-626
    • Fiacco, T.A.1    Agulhon, C.2    Taves, S.R.3    Petravicz, J.4    Casper, K.B.5    Dong, X.6    Chen, J.7    McCarthy, K.D.8
  • 51
    • 21644475992 scopus 로고    scopus 로고
    • Calcium dynamics in cortical astrocytes and arterioles during neurovascular coupling
    • Filosa JA, Bonev AD, Nelson MT (2004) Calcium dynamics in cortical astrocytes and arterioles during neurovascular coupling. Circ Res 95:73-81
    • (2004) Circ Res , vol.95 , pp. 73-81
    • Filosa, J.A.1    Bonev, A.D.2    Nelson, M.T.3
  • 54
    • 0025032599 scopus 로고
    • Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signals
    • Frostig RD, Lieke EE, Ts'o DY, Grinvald A (1990) Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signals. Proc Natl Acad Sci USA 87:6082-6
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6082-6086
    • Frostig, R.D.1    Lieke, E.E.2    Ts'O, D.Y.3    Grinvald, A.4
  • 55
    • 33751113978 scopus 로고    scopus 로고
    • Targeted bulkloading of fluorescent indicators for two-photon brain imaging in vivo
    • Garaschuk O, Milos RI, Konnerth A (2006) Targeted bulkloading of fluorescent indicators for two-photon brain imaging in vivo. Nat Protoc 1:380-6
    • (2006) Nat Protoc , vol.1 , pp. 380-386
    • Garaschuk, O.1    Milos, R.I.2    Konnerth, A.3
  • 56
    • 75949115986 scopus 로고    scopus 로고
    • Membrane potential dynamics of GABAergic neurons in the barrel cortex of behaving mice
    • Gentet LJ, Avermann M, Matyas F, Staiger JF, Petersen CH (2010) Membrane potential dynamics of GABAergic neurons in the barrel cortex of behaving mice. Neuron 65:422-35
    • (2010) Neuron , vol.65 , pp. 422-435
    • Gentet, L.J.1    Avermann, M.2    Matyas, F.3    Staiger, J.F.4    Petersen, C.H.5
  • 57
    • 0024805137 scopus 로고
    • Rodent models of cerebral ischemia
    • Ginsberg MD, Busto R (1989) Rodent models of cerebral ischemia. Stroke 20:1627-42 (Pubitemid 20030870)
    • (1989) Stroke , vol.20 , Issue.12 , pp. 1627-1642
    • Ginsberg, M.D.1    Busto, R.2
  • 58
    • 33644649803 scopus 로고    scopus 로고
    • Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease
    • Girouard H, Iadecola C (2006) Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease. J Appl Physiol 100:318-35
    • (2006) J Appl Physiol , vol.100 , pp. 318-335
    • Girouard, H.1    Iadecola, C.2
  • 59
    • 37549061420 scopus 로고    scopus 로고
    • New angles on neuronal dendrites in vivo
    • Göbel W, Helmchen F (2007) New angles on neuronal dendrites in vivo. J Neurophysiol 98:3770-9
    • (2007) J Neurophysiol , vol.98 , pp. 3770-3779
    • Göbel, W.1    Helmchen, F.2
  • 60
    • 33845961471 scopus 로고    scopus 로고
    • Imaging cellular network dynamics in three dimensions using fast 3D laser scanning
    • DOI 10.1038/nmeth989, PII NMETH989
    • Göbel W, Kampa BM, Helmchen F (2007) Imaging cellular network dynamics in three dimensions using fast 3D laser scanning. Nat Methods 4:73-9 (Pubitemid 46029479)
    • (2007) Nature Methods , vol.4 , Issue.1 , pp. 73-79
    • Gobel, W.1    Kampa, B.M.2    Helmchen, F.3
  • 61
    • 0034530003 scopus 로고    scopus 로고
    • A brainstem area mediating cerebrovascular and EEG responses to hypoxic excitation of rostal ventrolateral medulla in rat
    • DOI 10.1111/j.1469-7793.2000.00413.x
    • Golanov EV, Ruggiero DA, Reis DJ (2000) A brainstem area mediating cerebrovascular and EEG responses to hypoxic excitation of rostral ventrolateral medulla in rat. J Physiol 529:413-29 (Pubitemid 32007737)
    • (2000) Journal of Physiology , vol.529 , Issue.2 , pp. 413-429
    • Golanov, E.V.1    Ruggiero, D.A.2    Reis, D.J.3
  • 62
    • 35648934983 scopus 로고    scopus 로고
    • Identification of Alzheimer and vascular lesion thresholds for mixed dementia
    • DOI 10.1093/brain/awm228
    • Gold G, Giannakopoulos P, Herrmann FR, Bouras C, Kovari E (2007) Identification of Alzheimer and vascular lesion thresholds for mixed dementia. Brain 130:2830-6 (Pubitemid 350033968)
    • (2007) Brain , vol.130 , Issue.11 , pp. 2830-2836
    • Gold, G.1    Giannakopoulos, P.2    Herrmann, F.R.3    Bouras, C.4    Kovari, E.5
  • 64
    • 46049110525 scopus 로고    scopus 로고
    • Population imaging of ongoing neuronal activity in the visual cortex of awake rats
    • DOI 10.1038/nn.2140, PII NN2140
    • Greenberg DS, Houweling AR, Kerr JN (2008) Population imaging of ongoing neuronal activity in the visual cortex of awake rats. Nat Neurosci 11:749-51 (Pubitemid 351896680)
    • (2008) Nature Neuroscience , vol.11 , Issue.7 , pp. 749-751
    • Greenberg, D.S.1    Houweling, A.R.2    Kerr, J.N.D.3
  • 65
    • 0022997296 scopus 로고
    • Functional architecture of cortex revealed by optical imaging of intrinsic signals
    • DOI 10.1038/324361a0
    • Grinvald A, Lieke EE, Frostig RD, Gilbert CD, Wiesel TN (1986) Functional architecture of cortex revealed by optical imaging of intrinsic signals. Nature 324:361-4 (Pubitemid 17180109)
    • (1986) Nature , vol.324 , Issue.6095 , pp. 361-364
    • Grinvald, A.1    Lieke, E.2    Frostig, R.D.3
  • 66
    • 56649103770 scopus 로고    scopus 로고
    • Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review
    • Hainsworth AH, Markus HS (2008) Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review. J Cereb Blood Flow Metab 28: 1877-91
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1877-1891
    • Hainsworth, A.H.1    Markus, H.S.2
  • 67
    • 33645809129 scopus 로고    scopus 로고
    • Perivascular nerves and the regulation of cerebrovascular tone
    • DOI 10.1152/japplphysiol.00954.2005
    • Hamel E (2006) Perivascular nerves and the regulation of cerebrovascular tone. J Appl Physiol 100:1059-64 (Pubitemid 43671565)
    • (2006) Journal of Applied Physiology , vol.100 , Issue.3 , pp. 1059-1064
    • Hamel, E.1
  • 69
    • 30944450665 scopus 로고    scopus 로고
    • Deep tissue two-photon microscopy
    • DOI 10.1038/nmeth818, PII N818
    • Helmchen F, Denk W (2005) Deep tissue two-photon microscopy. Nat Methods 2:932-40 (Pubitemid 43108729)
    • (2005) Nature Methods , vol.2 , Issue.12 , pp. 932-940
    • Helmchen, F.1    Denk, W.2
  • 70
    • 55449083385 scopus 로고    scopus 로고
    • In vivo measurements of blood flow and glial cell function with two-photon laser scanning microscopy
    • Helmchen F, Kleinfeld D (2008) In vivo measurements of blood flow and glial cell function with two-photon laser scanning microscopy. Methods Enzymol 444:231-54
    • (2008) Methods Enzymol , vol.444 , pp. 231-254
    • Helmchen, F.1    Kleinfeld, D.2
  • 73
    • 77951568027 scopus 로고    scopus 로고
    • Photoacoustic imaging and characterization of the microvasculature
    • Hu S, Wang LV (2010) Photoacoustic imaging and characterization of the microvasculature. J Biomed Opt 15:011101
    • (2010) J Biomed Opt , vol.15 , pp. 011101
    • Hu, S.1    Wang, L.V.2
  • 74
    • 36648999131 scopus 로고    scopus 로고
    • The need for animal models in small-vessel brain disease
    • Hua R, Walz W (2006) The need for animal models in small-vessel brain disease. Crit Rev Neurobiol 18:5-11 (Pubitemid 350194077)
    • (2006) Critical Reviews in Neurobiology , vol.18 , Issue.1-2 , pp. 5-11
    • Hua, R.1    Walz, W.2
  • 75
    • 0028830779 scopus 로고
    • Video microscopy of cerebrocortical capillary flow: Response to hypotension and intracranial hypertension
    • Hudetz AG, Feher G, Weigle CGM, Knuese DE, Kampine JP (1995) Video microscopy of cerebrocortical capillary flow: response to hypotension and intracranial hypertension. Am J Physiol 268:H2202-10
    • (1995) Am J Physiol , vol.268
    • Hudetz, A.G.1    Feher, G.2    Weigle, C.G.M.3    Knuese, D.E.4    Kampine, J.P.5
  • 76
    • 33746698933 scopus 로고    scopus 로고
    • Spatial flow-volume dissociation of the cerebral microcirculatory response to mild hypercapnia
    • DOI 10.1016/j.neuroimage.2006.03.033, PII S1053811906002187
    • Hutchinson EB, Stefanovic B, Koretsky AP, Silva AC (2006) Spatial flow-volume dissociation of the cerebral microcirculatory response to mild hypercapnia. Neuroimage 32:520-30 (Pubitemid 44164622)
    • (2006) NeuroImage , vol.32 , Issue.2 , pp. 520-530
    • Hutchinson, E.B.1    Stefanovic, B.2    Koretsky, A.P.3    Silva, A.C.4
  • 77
    • 0022970092 scopus 로고
    • The sensory contribution of a single vibrissa's cortical barrel
    • Hutson KA, Masterton RB (1986) The sensory contribution of a single vibrissa's cortical barrel. J Neurophysiol 56:1196-223 (Pubitemid 17174139)
    • (1986) Journal of Neurophysiology , vol.56 , Issue.4 , pp. 1196-1223
    • Hutson, K.A.1    Masterton, R.B.2
  • 78
    • 35548969443 scopus 로고    scopus 로고
    • Glial regulation of the cerebral microvasculature
    • DOI 10.1038/nn2003, PII NN2003
    • Iadecola C, Nedergaard M (2007) Glial regulation of the cerebral microvasculature. Nat Neurosci 10:1369-76 (Pubitemid 350014688)
    • (2007) Nature Neuroscience , vol.10 , Issue.11 , pp. 1369-1376
    • Iadecola, C.1    Nedergaard, M.2
  • 80
    • 79551533195 scopus 로고    scopus 로고
    • What does local functional hyperemia tell about local neuronal activation?
    • Jukovskaya N, Tiret P, Lecoq J, Charpak S (2011) What does local functional hyperemia tell about local neuronal activation? J Neurosci 31:1579-82
    • (2011) J Neurosci , vol.31 , pp. 1579-1582
    • Jukovskaya, N.1    Tiret, P.2    Lecoq, J.3    Charpak, S.4
  • 85
    • 79959630869 scopus 로고    scopus 로고
    • Temporal dynamics and spatial specificity of aterial and venous blood volume changes during visual stimulation: Implication for BOLD quantification
    • Kim T, Kim SG (2011) Temporal dynamics and spatial specificity of aterial and venous blood volume changes during visual stimulation: implication for BOLD quantification. J Cereb Blood Flow Metab 31: 1211-1222
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 1211-1222
    • Kim, T.1    Kim, S.G.2
  • 86
    • 77953284706 scopus 로고    scopus 로고
    • Frequency-dependent neural activity, CBF, and BOLD fMRI in somatosensory stimuli in isofluraneanesthetized rats
    • Kim TN, Masamoto K, Fukada M, Vazquez A, Kim SG (2010) Frequency-dependent neural activity, CBF, and BOLD fMRI in somatosensory stimuli in isofluraneanesthetized rats. Neuroimage 52:224-33
    • (2010) Neuroimage , vol.52 , pp. 224-233
    • Kim, T.N.1    Masamoto, K.2    Fukada, M.3    Vazquez, A.4    Kim, S.G.5
  • 87
    • 85013198467 scopus 로고    scopus 로고
    • Cortical blood flow through individual capillaries in rat vibrissa S1 cortex: Stimulus induced changes are comparable to underlying fluctuations in flow
    • (Tomita M, ed), Tokyo: Elsevier International Congress Series
    • Kleinfeld D (2002) Cortical blood flow through individual capillaries in rat vibrissa S1 cortex: stimulus induced changes are comparable to underlying fluctuations in flow. In: Brain activation and cerebral blood flow control Vol. 892. (Tomita M, ed), Tokyo: Elsevier International Congress Series, 115-22
    • (2002) Brain Activation and Cerebral Blood Flow Control , vol.892 , pp. 115-122
    • Kleinfeld, D.1
  • 89
    • 0029910183 scopus 로고    scopus 로고
    • Distributed representation of vibrissa movement in the upper layers of somatosensory cortex revealed with voltage-sensitive dyes
    • DOI 10.1002/(SICI)1096-9861(19961104)375:1<89::AID-CNE6>3.0.CO;2-K
    • Kleinfeld D, Delaney KR (1996) Distributed representation of vibrissa movement in the upper layers of somatosensory cortex revealed with voltage sensitive dyes. J Comp Neurol 375:89-108 (Pubitemid 26378146)
    • (1996) Journal of Comparative Neurology , vol.375 , Issue.1 , pp. 89-108
    • Kleinfeld, D.1    Delaney, K.R.2
  • 90
    • 4544343277 scopus 로고    scopus 로고
    • Two-photon imaging of neocortical microcirculation
    • (Yuste R, Lanni F, Konnerth A, eds), Cold Spring Harbor: Cold Spring Harbor Laboratory Press
    • Kleinfeld D, Denk W (1999) Two-photon imaging of neocortical microcirculation. In: Imaging neurons: a laboratory manual (Yuste R, Lanni F, Konnerth A, eds), Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 23.1-5
    • (1999) Imaging Neurons: A Laboratory Manual , vol.23 , pp. 1-5
    • Kleinfeld, D.1    Denk, W.2
  • 91
    • 84900633997 scopus 로고    scopus 로고
    • Targeted occlusion to surface and deep vessels in neocortex via linear and nonlinear optical absorption
    • Chen J, Xu Z, Xu X-M, Zhang J, eds The Humana Press: New York, NY
    • Kleinfeld D, Friedman B, Lyden PD, Shih AY (2008) Targeted occlusion to surface and deep vessels in neocortex via linear and nonlinear optical absorption. In: Animal models of acute neurological injuries (Chen J, Xu Z, Xu X-M, Zhang J, eds), Vol. 14. The Humana Press: New York, NY, pp 169-85
    • (2008) Animal Models of Acute Neurological Injuries , vol.14 , pp. 169-185
    • Kleinfeld, D.1    Friedman, B.2    Lyden, P.D.3    Shih, A.Y.4
  • 92
    • 79957783070 scopus 로고    scopus 로고
    • Applications of spectral methods in functional brain imaging
    • (Yuste R, ed), New York: Cold Spring Harbor Laboratory Press
    • Kleinfeld D, Mitra PP (2011) Applications of spectral methods in functional brain imaging. In: Imaging: a laboratory manual Vol. 1. (Yuste R, ed), New York: Cold Spring Harbor Laboratory Press, 12.1-7
    • (2011) Imaging: A Laboratory Manual , vol.1 , pp. 121-127
    • Kleinfeld, D.1    Mitra, P.P.2
  • 94
    • 33748143364 scopus 로고    scopus 로고
    • Haptic object localization in the vibrissal system: Behavior and performance
    • Knutsen PM, Pietr M, Ahissar E (2006) Haptic object localization in the vibrissal system: behavior and performance. J Neurosci 26:8451-64
    • (2006) J Neurosci , vol.26 , pp. 8451-8464
    • Knutsen, P.M.1    Pietr, M.2    Ahissar, E.3
  • 95
    • 0025612862 scopus 로고
    • Role of adenosine in regulation of regional cerebral blood flow in sensory cortex
    • Ko KR, Ngai AC, Winn HR (1990) Role of adenosine in regulation of regional cerebral blood flow in sensory cortex. Am J Physiol 259:H1703-8
    • (1990) Am J Physiol , vol.259
    • Ko, K.R.1    Ngai, A.C.2    Winn, H.R.3
  • 98
    • 0024546198 scopus 로고
    • Validity of cerebral arterial blood flow calculations from velocity measurements
    • Kontos HA (1989) Validity of cerebral arterial blood flow calculations from velocity measurements. Stroke 20:1-3 (Pubitemid 19040205)
    • (1989) Stroke , vol.20 , Issue.1 , pp. 1-3
    • Kontos, H.A.1
  • 99
    • 34147092550 scopus 로고    scopus 로고
    • Cortical microinfarcts and demyelination affect cognition in cases at high risk for dementia
    • DOI 10.1212/01.wnl.0000257094.10655.9a, PII 0000611420070320000013
    • Kövari E, Gold G, Herrmann FR, Canuto A, Hof PR, Bouras C, Giannakopoulos P (2007) Cortical microinfarcts and demyelination affect cognition in cases at high risk for dementia. Neurology 66:927-31 (Pubitemid 46568505)
    • (2007) Neurology , vol.68 , Issue.12 , pp. 927-931
    • Kovari, E.1    Gold, G.2    Herrmann, F.R.3    Canuto, A.4    Hof, P.R.5    Bouras, C.6    Giannakopoulos, P.7
  • 100
    • 0842310806 scopus 로고    scopus 로고
    • Cortical Microinfarcts and Demyelination Significantly Affect Cognition in Brain Aging
    • DOI 10.1161/01.STR.0000110791.51378.4E
    • Kovari E, Gold G, Herrmann FR, Canuto A, Hof PR, Michel JP, Bouras C, Giannakopoulos P (2004) Cortical microinfarcts and demyelination significantly affect cognition in brain aging. Stroke 35:410-4 (Pubitemid 38174421)
    • (2004) Stroke , vol.35 , Issue.2 , pp. 410-414
    • Kovari, E.1    Gold, G.2    Herrmann, F.R.3    Canuto, A.4    Hof, P.R.5    Michel, J.-P.6    Bouras, C.7    Giannakopoulos, P.8
  • 101
    • 0035425617 scopus 로고    scopus 로고
    • Behavioral properties of the trigeminal somatosensory system in rats performing whisker-dependent tactile discriminations
    • Krupa DJ, Matell MS, Brisben AJ, Oliveira LM, Nicolelis MAL (2001) Behavioral properties of the trigeminal somatosensory system in rats performing whisker-dependent tactile discriminations. J Neurosci 21:5752-63 (Pubitemid 32692174)
    • (2001) Journal of Neuroscience , vol.21 , Issue.15 , pp. 5752-5763
    • Krupa, D.J.1    Matell, M.S.2    Brisben, A.J.3    Oliveira, L.M.4    Nicolelis, M.A.L.5
  • 102
    • 61349096009 scopus 로고    scopus 로고
    • Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice
    • Kuchibhotla KV, Lattarula CR, Hyman BT, Bacskai BJ (2009) Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice. Science 323:1211-5
    • (2009) Science , vol.323 , pp. 1211-1215
    • Kuchibhotla, K.V.1    Lattarula, C.R.2    Hyman, B.T.3    Bacskai, B.J.4
  • 103
    • 44849103425 scopus 로고    scopus 로고
    • High-resolution labeling and functional manipulation of specific neuron types in mouse brain by cre-activated viral gene expression
    • Kuhlman SJ, Huang JZ (2008) High-resolution labeling and functional manipulation of specific neuron types in mouse brain by cre-activated viral gene expression. PLoS ONE 3:1-11
    • (2008) PLoS ONE , vol.3 , pp. 1-11
    • Kuhlman, S.J.1    Huang, J.Z.2
  • 104
  • 106
    • 59649119749 scopus 로고    scopus 로고
    • Odor-evoked oxygen consumption by action potential and synaptic transmission in the olfactory bulb
    • Lecoq JL, Tiret P, Najac M, Sheperd GM, Greer CA, Charpak S (2009) Odor-evoked oxygen consumption by action potential and synaptic transmission in the olfactory bulb. J Neurosci 29:1424-33
    • (2009) J Neurosci , vol.29 , pp. 1424-1433
    • Lecoq, J.L.1    Tiret, P.2    Najac, M.3    Sheperd, G.M.4    Greer, C.A.5    Charpak, S.6
  • 108
    • 0025232287 scopus 로고
    • Enhanced vasomotion of cerebral arterioles in spontaneously hypertensive rats
    • DOI 10.1016/0026-2862(90)90065-Y
    • Lefer DJ, Lynch CD, Lapinski KC, Hutchins PM (1990) Enhanced vasomotion of cerebral arterioles in sponaneously hypertensive rats. Microvasc Res 39:129-39 (Pubitemid 20154440)
    • (1990) Microvascular Research , vol.39 , Issue.2 , pp. 129-139
    • Lefer, D.J.1    Lynch, C.D.2    Lapinski, K.C.3    Hutchins, P.M.4
  • 109
    • 0016814997 scopus 로고
    • Detailed description of a cranial window technique for acute and chronic experiments
    • Levasseur JE, Wei EP, Raper AJ, Kontos AA, Patterson JL (1975) Detailed description of a cranial window technique for acute and chronic experiments. Stroke 6:308-17
    • (1975) Stroke , vol.6 , pp. 308-317
    • Levasseur, J.E.1    Wei, E.P.2    Raper, A.J.3    Kontos, A.A.4    Patterson, J.L.5
  • 111
    • 21844436786 scopus 로고    scopus 로고
    • 3)-receptor type 2-deficient mice
    • DOI 10.1161/01.RES.0000172556.05576.4c
    • Li X, Zima AV, Sheikh F, Blatter LA, Chen J (2005) Endothelin-1-induced arrhythmogenic Ca2+ signaling is abolished in atrial myocytes of inositol-1,4, 5-triphosphte(IP3)-receptor type 2-deficient mice. Circ Res 96:1274-81 (Pubitemid 40962105)
    • (2005) Circulation Research , vol.96 , Issue.12 , pp. 1274-1281
    • Li, X.1    Zima, A.V.2    Sheikh, F.3    Blatter, L.A.4    Chen, J.5
  • 112
    • 46249127575 scopus 로고    scopus 로고
    • Two-photon imaging of spatially extended neuronal network dynamics with high temporal resolution
    • Lillis KP, Eng A, White JA, Mertz J (2008) Two-photon imaging of spatially extended neuronal network dynamics with high temporal resolution. J Neurosci Methods 172:178-84
    • (2008) J Neurosci Methods , vol.172 , pp. 178-184
    • Lillis, K.P.1    Eng, A.2    White, J.A.3    Mertz, J.4
  • 114
    • 33646909651 scopus 로고    scopus 로고
    • Distinct subtypes of somatostatin-containing neocortical interneurons revealed in transgenic mice
    • DOI 10.1523/JNEUROSCI.0661-06.2006
    • Ma Y, Hu H, Berrebi AS, Mathers PH, Agmon A (2006) Distinct subtypes of somatostatin-containing neocortical interneurons revealed in transgenic mice. J Neurosci 26:5069-82 (Pubitemid 44315288)
    • (2006) Journal of Neuroscience , vol.26 , Issue.19 , pp. 5069-5082
    • Ma, Y.1    Hu, H.2    Berrebi, A.S.3    Mathers, P.H.4    Agmon, A.5
  • 115
    • 0032956914 scopus 로고    scopus 로고
    • Homing with locale, taxon, and dead reckoning strategies by foraging rats: Sensory hierarchy in spatial navigation
    • DOI 10.1016/S0166-4328(98)00100-4, PII S0166432898001004
    • Maaswinkel H, Whishaw IQ (1999) Homing with locale, taxon, and dead reckoning strategies by foraging rats: Sensory hierarchy in spatial navigation. Behav Brain Res 99:143-52 (Pubitemid 29083441)
    • (1999) Behavioural Brain Research , vol.99 , Issue.2 , pp. 143-152
    • Maaswinkel, H.1    Whishaw, I.Q.2
  • 119
    • 80055106291 scopus 로고    scopus 로고
    • A thin-skull window technique for chronic two-photon in vivo imaging of murine microglia in models of neuroinflammation
    • Marker DF, Tremblay ME, Lu SM, Majewska AK, Gelbard HA (2010) A thin-skull window technique for chronic two-photon in vivo imaging of murine microglia in models of neuroinflammation. J Vis Exp 19:e2059
    • (2010) J Vis Exp , vol.19
    • Marker, D.F.1    Tremblay, M.E.2    Lu, S.M.3    Majewska, A.K.4    Gelbard, H.A.5
  • 120
    • 33748637368 scopus 로고    scopus 로고
    • Investigating neural-hemodynamic coupling and the hemodynamic response function in the awake rat
    • Martin C, Martindale J, Berwick J, Mayhew J (2006) Investigating neural-hemodynamic coupling and the hemodynamic response function in the awake rat. Neuroimage 32:33-48
    • (2006) Neuroimage , vol.32 , pp. 33-48
    • Martin, C.1    Martindale, J.2    Berwick, J.3    Mayhew, J.4
  • 122
    • 79952195106 scopus 로고    scopus 로고
    • In vivo 3D morphology of astrocyte-vasculature interactions in the somatosensory cortex: Implications for neurovascular coupling
    • McCaslin AF, Chen BR, Radosevich AJ, Cauli B, Hillman EM (2010) In vivo 3D morphology of astrocyte-vasculature interactions in the somatosensory cortex: implications for neurovascular coupling. J Cereb Blood Flow Metab 31:795-806
    • (2010) J Cereb Blood Flow Metab , vol.31 , pp. 795-806
    • McCaslin, A.F.1    Chen, B.R.2    Radosevich, A.J.3    Cauli, B.4    Hillman, E.M.5
  • 123
    • 0002487498 scopus 로고
    • Biological effects of blood loss: Implications for sampling volumes and techniques
    • McGuill MW, Rowan AN (1989) Biological effects of blood loss: implications for sampling volumes and techniques. ILAR News 31:5-20
    • (1989) ILAR News , vol.31 , pp. 5-20
    • McGuill, M.W.1    Rowan, A.N.2
  • 125
    • 33750730317 scopus 로고    scopus 로고
    • Ach dilates pial arterioles in endothelial and neuronal NOS knockout mice but NOdependent mechanisms
    • Meng W, Ma J, Ayata C, Hara H, Huang PL, Fishman MC, Moskowitz MA (1996) Ach dilates pial arterioles in endothelial and neuronal NOS knockout mice but NOdependent mechanisms. Am J Physiol 271:H1145-50
    • (1996) Am J Physiol , vol.271
    • Meng, W.1    Ma, J.2    Ayata, C.3    Hara, H.4    Huang, P.L.5    Fishman, M.C.6    Moskowitz, M.A.7
  • 126
    • 54749125078 scopus 로고    scopus 로고
    • Highspeed varifocal imaging with a tunable acoustic gradient index of refraction lens
    • Mermillod-Blondin A, McLeod E, Arnold CB (2008) Highspeed varifocal imaging with a tunable acoustic gradient index of refraction lens. Opt Lett 33:2146-8
    • (2008) Opt Lett , vol.33 , pp. 2146-2148
    • Mermillod-Blondin, A.1    McLeod, E.2    Arnold, C.B.3
  • 127
    • 33745740498 scopus 로고    scopus 로고
    • In vivo imaging of the diseased nervous system
    • DOI 10.1038/nrn1905, PII NRN1905
    • Misgeld T, Kerschensteiner M (2006) In vivo imaging of the diseased nervous system. Nat Rev Neurosci 7:449-63 (Pubitemid 44012285)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.6 , pp. 449-463
    • Misgeld, T.1    Kerschensteiner, M.2
  • 128
    • 79959355101 scopus 로고    scopus 로고
    • Targeted mini-strokes produce changes in interhemispheric sensory signal processing that are indicative of disinhibition within minutes
    • Mohajerani M, Aminoltejari K, Murphy TH (2011) Targeted mini-strokes produce changes in interhemispheric sensory signal processing that are indicative of disinhibition within minutes. Proc Natl Acad Sci 108: E183-91
    • (2011) Proc Natl Acad Sci , vol.108
    • Mohajerani, M.1    Aminoltejari, K.2    Murphy, T.H.3
  • 129
    • 57749193733 scopus 로고    scopus 로고
    • Tracheotomy improves experiment success rate in mice during urethane anesthesia and sterotaxic surgery
    • Moldestad O, Karlsen P, Molden S, Storm JF (2009) Tracheotomy improves experiment success rate in mice during urethane anesthesia and sterotaxic surgery. J Neurosc Methods 176:57-62
    • (2009) J Neurosc Methods , vol.176 , pp. 57-62
    • Moldestad, O.1    Karlsen, P.2    Molden, S.3    Storm, J.F.4
  • 130
    • 0022607349 scopus 로고
    • Reactivity of rat pial arterioles and venules to adenosine and carbon dioxide: With detailed description of the closed cranial window technique in rats
    • Morii S, Ngai AC, Winn HR (1986) Reactivity of rat pial arterioles and venules to adenosine and carbon dioxide: with detailed description of the closed cranial window technique in rats. J Cereb Blood Flow Metab 6:34-41 (Pubitemid 16153663)
    • (1986) Journal of Cerebral Blood Flow and Metabolism , vol.6 , Issue.1 , pp. 34-41
    • Morii, S.1    Ngai, A.C.2    Winn, H.R.3
  • 131
    • 80055117408 scopus 로고    scopus 로고
    • A method for 2-photon imaging of blood flow in the neocortex through a cranial window
    • Mostany R, Portera-Cailliau C (2008) A method for 2-photon imaging of blood flow in the neocortex through a cranial window. J Vis Exp 12:678
    • (2008) J Vis Exp , vol.12 , pp. 678
    • Mostany, R.1    Portera-Cailliau, C.2
  • 132
    • 79551558838 scopus 로고    scopus 로고
    • Absence of large-scale dendritic plasticity of layer 5 pyramidal neurons in periinfarct cortex
    • Mostany R, Portera-Cailliau C (2011) Absence of large-scale dendritic plasticity of layer 5 pyramidal neurons in periinfarct cortex. J Neurosci 31:1734-8
    • (2011) J Neurosci , vol.31 , pp. 1734-1738
    • Mostany, R.1    Portera-Cailliau, C.2
  • 134
    • 4544222190 scopus 로고    scopus 로고
    • Calcium transients in astrocyte endfeet cause cerebrovascular constrictions
    • DOI 10.1038/nature02827
    • Mulligan SJ, MacVicar BA (2004) Calcium transients in astrocyte endfeet cause cerebrovascular constrictions. Nature 431:195-9 (Pubitemid 39243473)
    • (2004) Nature , vol.431 , Issue.7005 , pp. 195-199
    • Mulligan, S.J.1    MacVicar, B.A.2
  • 136
    • 39549116502 scopus 로고    scopus 로고
    • Two-photon imaging of stroke onset in vivo reveals that NMDAreceptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines
    • Murphy TH, Li P, Betts K, Liu R (2008b) Two-photon imaging of stroke onset in vivo reveals that NMDAreceptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines. J Neurosc 28:756-72
    • (2008) J Neurosc , vol.28 , pp. 756-772
    • Murphy, T.H.1    Li, P.2    Betts, K.3    Liu, R.4
  • 137
    • 0023840436 scopus 로고
    • Effect of sciatic nerve stimulation on pial arterioles in rats
    • Ngai AC, Ko KR, Morii S, Winn HR (1988) Effect of sciatic nerve stimulation on pial arterioles in rats. Am J Physiol 254:H133-9
    • (1988) Am J Physiol , vol.254
    • Ngai, A.C.1    Ko, K.R.2    Morii, S.3    Winn, H.R.4
  • 138
    • 0028789715 scopus 로고
    • L-NNA suppresses cerebrovascular response and evoked potentials during somatosensory stimulation in rats
    • Ngai AC, Meno JR, Winn HR (1995) L-NNA suppresses cerebrovascular response and evoked potentials during somatosensory stimulation in rats. Am J Physiol 269:H1803-10 (Pubitemid 3005977)
    • (1995) The American journal of physiology , vol.269 , Issue.52
    • Ngai, A.C.1    Meno, J.R.2    Winn, H.R.3
  • 139
    • 80455174013 scopus 로고    scopus 로고
    • Occlusion of cortical ascending venules causes blood flow decreases, reversals in flow direction, and vessel dilation in upstream capillaries
    • Nguyen J, Nishimura N, Fetcho R, Iadecola C, Schaffer CB (2011) Occlusion of cortical ascending venules causes blood flow decreases, reversals in flow direction, and vessel dilation in upstream capillaries. J Cereb Blood Flow Metab 31:2243-54
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 2243-2254
    • Nguyen, J.1    Nishimura, N.2    Fetcho, R.3    Iadecola, C.4    Schaffer, C.B.5
  • 140
    • 33744946245 scopus 로고    scopus 로고
    • MPScope: A versatile software suite for multiphoton microscopy
    • DOI 10.1016/j.jneumeth.2006.03.001, PII S0165027006001397
    • Nguyen Q-T, Tsai PS, Kleinfeld D (2006) MPScope: a versatile software suite for multiphoton microscopy. J Neurosci Methods 156:351-9 (Pubitemid 44233677)
    • (2006) Journal of Neuroscience Methods , vol.156 , Issue.1-2 , pp. 351-359
    • Nguyen, Q.-T.1    Tsai, P.S.2    Kleinfeld, D.3
  • 141
    • 70949093606 scopus 로고    scopus 로고
    • MPScope 2.0: A computer system for two-photon laser scanning microscopy with concurrent plasma-mediated ablation and electrophysiology
    • 2nd ed. Frostig RD, ed, Boca Raton: CRC Press
    • Nguyen Q-T, Dolnick EM, Driscoll J, Kleinfeld D (2009) MPScope 2.0: A computer system for two-photon laser scanning microscopy with concurrent plasma-mediated ablation and electrophysiology. In: Methods for in vivo optical imaging 2nd ed. (Frostig RD, ed), Boca Raton: CRC Press, 117-42
    • (2009) Methods for in Vivo Optical Imaging , pp. 117-142
    • Nguyen, Q.-T.1    Dolnick, E.M.2    Driscoll, J.3    Kleinfeld, D.4
  • 143
    • 23244435013 scopus 로고    scopus 로고
    • Neuroscience: Hemodynamic signals correlate tightly with synchronized gamma oscillations
    • DOI 10.1126/science.1110948
    • Niessing J, Ebisch B, Schmidt KE, Niessing M, Singer W, Galuske RA (2005) Hemodynamic signals correlate tightly with synchronized gamma oscillations. Science 309:948-51 (Pubitemid 41099934)
    • (2005) Science , vol.309 , Issue.5736 , pp. 948-951
    • Niessing, J.1    Ebisch, B.2    Schmidt, K.E.3    Niessing, M.4    Singer, W.5    Galuske, R.A.W.6
  • 144
    • 18744409106 scopus 로고    scopus 로고
    • Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
    • Nimmerjahn A, Kirchhoff F, Kerr JN, Helmchen F (2004) Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat Methods 29:31-7
    • (2004) Nat Methods , vol.29 , pp. 31-37
    • Nimmerjahn, A.1    Kirchhoff, F.2    Kerr, J.N.3    Helmchen, F.4
  • 146
    • 78649708330 scopus 로고    scopus 로고
    • Limitations of collateral flow after occlusion of a single cortical penetrating arteriole
    • Nishimura N, Rosidi NL, Iadecola C, Schaffer CB (2010) Limitations of collateral flow after occlusion of a single cortical penetrating arteriole. J Cereb Blood Flow Metab 30:1914-27
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1914-1927
    • Nishimura, N.1    Rosidi, N.L.2    Iadecola, C.3    Schaffer, C.B.4
  • 148
    • 31744448499 scopus 로고    scopus 로고
    • Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: Three models of stroke
    • DOI 10.1038/nmeth844, PII N844
    • Nishimura N, Schaffer CB, Friedman B, Tsai PS, Lyden PD, Kleinfeld D (2006) Targeted insult to individual subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke. Nat Methods 3:99-108 (Pubitemid 43173308)
    • (2006) Nature Methods , vol.3 , Issue.2 , pp. 99-108
    • Nishimura, N.1    Schaffer, C.B.2    Friedman, B.3    Tsai, P.S.4    Lyden, P.D.5    Kleinfeld, D.6
  • 149
    • 0035132767 scopus 로고    scopus 로고
    • GFAP promoter-controlled EGFP-expressing transgenic mice: A tool to visualize astrocytes and astrogliosis in living brain tissue
    • DOI 10.1002/1098-1136(20010101)33:1<72::AID-GLIA1007>3.0.CO;2-A
    • Nolte C, Matyash M, Pivneva T, Schipke CG, Ohlemeyer C, Hanisch UK, Kirchhoff F, Kettenmann H (2001) GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue. Glia 33:72-86 (Pubitemid 32102818)
    • (2001) GLIA , vol.33 , Issue.1 , pp. 72-86
    • Nolte, C.1    Matyash, M.2    Pivneva, T.3    Schipke, C.G.4    Ohlemeyer, C.5    Hanisch, U.-K.6    Kirchhoff, F.7    Kettenmann, H.8
  • 151
    • 0026754226 scopus 로고
    • Intrinsic signal changes accompanying sensory stimulation: Functional brain mapping with magnetic resonance imaging
    • Ogawa S, Tank DW, Menon R, Ellermann JM, Kim S-G, Merkle H, Ugurbil K (1992) Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 89:5951-5
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5951-5955
    • Ogawa, S.1    Tank, D.W.2    Menon, R.3    Ellermann, J.M.4    Kim, S.-G.5    Merkle, H.6    Ugurbil, K.7
  • 152
  • 154
    • 0343569849 scopus 로고    scopus 로고
    • Novel hippocampal interneuronal subtypes identified using transgenic mice that express green fluorescent protein in GABAergic interneurons
    • Oliva AA, Jr, Jiang M, Lam T, Smith TL, Swann JW (2000) Novel hippocampal interneuronal subtypes identified using transgenic mice that express green fluorescent protein in GABAergic interneurons. J Neurosci 20: 3354-68 (Pubitemid 30263151)
    • (2000) Journal of Neuroscience , vol.20 , Issue.9 , pp. 3354-3368
    • Oliva Jr., A.A.1    Jiang, M.2    Lam, T.3    Smith, K.L.4    Swann, J.W.5
  • 155
    • 67649364233 scopus 로고    scopus 로고
    • Two-photon microscopy with simultaneous standard and extended depth of field using a tunable acoustic gradient-index lens
    • Olivier N, Mermillod-Blondin A, Arnold CB, Beaurepaire E (2009) Two-photon microscopy with simultaneous standard and extended depth of field using a tunable acoustic gradient-index lens. Opt Lett 34:1684-6
    • (2009) Opt Lett , vol.34 , pp. 1684-1686
    • Olivier, N.1    Mermillod-Blondin, A.2    Arnold, C.B.3    Beaurepaire, E.4
  • 157
    • 33749860102 scopus 로고    scopus 로고
    • Bidirectional control of CNS capillary diameter by pericytes
    • Peppiatt CM, Howarth C, Mobbs P, Attwell D (2006) Bidirectional control of CNS capillary diameter by pericytes. Nature 443:642-3
    • (2006) Nature , vol.443 , pp. 642-643
    • Peppiatt, C.M.1    Howarth, C.2    Mobbs, P.3    Attwell, D.4
  • 158
    • 45249086342 scopus 로고    scopus 로고
    • Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways
    • Petzold GC, Albeanu DF, Sato TF, Murthy VN (2008) Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways. Neuron 58:879-910
    • (2008) Neuron , vol.58 , pp. 879-910
    • Petzold, G.C.1    Albeanu, D.F.2    Sato, T.F.3    Murthy, V.N.4
  • 160
    • 44349134543 scopus 로고    scopus 로고
    • Three-dimensional random access multiphoton microscopy for functional imaging of neuronal activity
    • DOI 10.1038/nn.2116, PII NN2116
    • Reddy GD, Kelleher K, Fink R, Saggau P (2008) Threedimensional random access multiphoton microscopy for fast functional imaging of neuronal activity. Nat Neurosci 11:713-20 (Pubitemid 351748113)
    • (2008) Nature Neuroscience , vol.11 , Issue.6 , pp. 713-720
    • Duemani Reddy, G.1    Kelleher, K.2    Fink, R.3    Saggau, P.4
  • 161
    • 33645218765 scopus 로고    scopus 로고
    • Fast three-dimensional laser scanning scheme using acousto-optic deflectors
    • Reddy GD, Saggau P (2005) Fast three-dimensional laser scanning scheme using acousto-optic deflectors. J Biomed Opt 10:064038
    • (2005) J Biomed Opt , vol.10 , pp. 064038
    • Reddy, G.D.1    Saggau, P.2
  • 163
    • 0027175879 scopus 로고
    • Blood flow in single surface arterioles and venules on the mouse somatosensory cortex measured with videomicroscopy, fluorescent dextrans, nonoccluding fluorescent beads, and computer-assisted image analysis
    • Rovainen CM, Woolsey TA, Blocher NC, Wang D-B, Robinson OF (1993) Blood flow in single surface arterioles and venules on the mouse somatosensory cortex measured with videomicroscopy, fluorescent dextrans, nonoccluding fluorescent
    • (1993) Journal of Cerebral Blood Flow and Metabolism , vol.13 , Issue.3 , pp. 359-371
    • Rovainen, C.M.1    Woolsey, T.A.2    Blocher, N.C.3    Wang, D.-B.4    Robinson, O.F.5
  • 164
    • 84944817192 scopus 로고
    • On the regulation of the blood supply of the brain
    • Roy CS, Sherington CS (1890) On the regulation of the blood supply of the brain. J Physiol 11:85-108
    • (1890) J Physiol , vol.11 , pp. 85-108
    • Roy, C.S.1    Sherington, C.S.2
  • 169
    • 33244478081 scopus 로고    scopus 로고
    • Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion
    • DOI 10.1371/journal.pbio.0040022
    • Schaffer CB, Friedman B, Nishimura N, Schroeder LF, Tsai PS, Ebner FF, Lyden PD, Kleinfeld D (2006) Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. PLoSci Biol 4:258-70 (Pubitemid 43275855)
    • (2006) PLoS Biology , vol.4 , Issue.2 , pp. 258-270
    • Schaffer, C.B.1    Friedman, B.2    Nishimura, N.3    Schroeder, L.F.4    Tsai, P.S.5    Ebner, F.F.6    Lyden, P.D.7    Kleinfeld, D.8
  • 170
    • 0001866705 scopus 로고
    • Cerebral vascular system
    • (Paxinos G, ed), 2nd ed. San Diego: Academic Press, Inc.
    • Scremin OU (1995) Cerebral vascular system. In: The rat nervous system (Paxinos G, ed), 2nd ed. San Diego: Academic Press, Inc., 3-35
    • (1995) The Rat Nervous System , pp. 3-35
    • Scremin, O.U.1
  • 171
    • 33750856804 scopus 로고    scopus 로고
    • A model for red blood cell motion in glycocalyx-lined capillaries
    • Secomb TW, Hsu R, Pries AR (1998) A model for red blood cell motion in glycocalyx-lined capillaries. Am J Physiol 274:H1016-22
    • (1998) Am J Physiol , vol.274
    • Secomb, T.W.1    Hsu, R.2    Pries, A.R.3
  • 172
    • 79960361861 scopus 로고    scopus 로고
    • Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters
    • Shigetomi E, Kracun S, Khakh BS (2010) Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters. Neuron Glia Biol 6:183-91
    • (2010) Neuron Glia Biol , vol.6 , pp. 183-191
    • Shigetomi, E.1    Kracun, S.2    Khakh, B.S.3
  • 173
    • 63949087753 scopus 로고    scopus 로고
    • Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke
    • Shih AY, Friedman B, Drew PJ, Tsai PS, Lyden PD, Kleinfeld D (2009) Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke. J Cereb Blood Flow Metab 29:738-51
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 738-751
    • Shih, A.Y.1    Friedman, B.2    Drew, P.J.3    Tsai, P.S.4    Lyden, P.D.5    Kleinfeld, D.6
  • 174
    • 84863770669 scopus 로고    scopus 로고
    • A polished and reinforced thinned skull window for long-termimaging of mouse cortex
    • doi: 10.3791/3742 in press)
    • Shih AY, Mateo C, Drew PJ, Tsai PS, Kleinfeld D (2012) A polished and reinforced thinned skull window for long-termimaging of mouse cortex. J Vis Exp, e3742; doi: 10.3791/3742 (in press)
    • (2012) J Vis Exp
    • Shih, A.Y.1    Mateo, C.2    Drew, P.J.3    Tsai, P.S.4    Kleinfeld, D.5
  • 176
    • 67650915104 scopus 로고    scopus 로고
    • Imaging rapid redistribution of sensory-evoked depolarization through existing cortical pathways after targeted stroke in mice
    • Sigler A, Mohajerani MH, Murphy TH (2009) Imaging rapid redistribution of sensory-evoked depolarization through existing cortical pathways after targeted stroke in mice. Proc Natl Acad Sci USA 106:11758-64
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11758-11756
    • Sigler, A.1    Mohajerani, M.H.2    Murphy, T.H.3
  • 177
    • 58749113429 scopus 로고    scopus 로고
    • Anticipatory haemodynamic signals in sensory cortex not predicted by local neuronal activity
    • Sirotin YB, Das A (2008) Anticipatory haemodynamic signals in sensory cortex not predicted by local neuronal activity. Nature 457:475-9
    • (2008) Nature , vol.457 , pp. 475-479
    • Sirotin, Y.B.1    Das, A.2
  • 178
    • 33847185168 scopus 로고    scopus 로고
    • GABAergic neurons are less selective to stimulus orientation than excitatory neurons in layer II/III of visual cortex, as revealed by in vivo functional Ca2+ imaging in transgenic mice
    • Sohya K, Kameyama K, Yanagawa Y, Obata K, Tsumoto T (2007) GABAergic neurons are less selective to stimulus orientation than excitatory neurons in layer II/III of visual cortex, as revealed by in vivo functional Ca2+ imaging in transgenic mice. J Neurosci 27:2145-9
    • (2007) J Neurosci , vol.27 , pp. 2145-2149
    • Sohya, K.1    Kameyama, K.2    Yanagawa, Y.3    Obata, K.4    Tsumoto, T.5
  • 183
    • 0036327648 scopus 로고    scopus 로고
    • Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease
    • DOI 10.1161/01.STR.0000024523.82311.77
    • Suter OC, Sunthorn T, Kraftsik R, Straubel J, Darekar P, Khalili K, Miklossy J (2002) Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease. Stroke 33:1986-92 (Pubitemid 34840055)
    • (2002) Stroke , vol.33 , Issue.8 , pp. 1986-1992
    • Suter, O.-C.1    Sunthorn, T.2    Kraftsik, R.3    Straubel, J.4    Darekar, P.5    Khalili, K.6    Miklossy, J.7
  • 185
    • 0242300262 scopus 로고    scopus 로고
    • Green Fluorescent Protein Expression and Colocalization with Calretinin, Parvalbumin, and Somatostatin in the GAD67-GFP Knock-In Mouse
    • DOI 10.1002/cne.10905
    • Tamamaki N, Yanagawa T, Tomioka R, Miyazaki J, Obata K, Kaneko T (2003) Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse. J Comp Neurol 40:60-79 (Pubitemid 37339758)
    • (2003) Journal of Comparative Neurology , vol.467 , Issue.1 , pp. 60-79
    • Tamamaki, N.1    Yanagawa, Y.2    Tomioka, R.3    Miyazaki, J.-I.4    Obata, K.5    Kaneko, T.6
  • 186
    • 0038648569 scopus 로고    scopus 로고
    • Two-photon imaging to a depth of 1000 micrometers in living brains by use of a Ti:Al2O3 regenerative amplifier
    • Theer P, Hasan MT, Denk W (2003) Two-photon imaging to a depth of 1000 micrometers in living brains by use of a Ti:Al2O3 regenerative amplifier. Opt Lett 28:1022-4
    • (2003) Opt Lett , vol.28 , pp. 1022-1024
    • Theer, P.1    Hasan, M.T.2    Denk, W.3
  • 187
    • 33845887246 scopus 로고    scopus 로고
    • On the fundamental imaging-depth limit in two-photon microscopy
    • Theer P, DenkW(2006) On the fundamental imaging-depth limit in two-photon microscopy. J Opt Soc Am A Opt Image Sci Vis 23:3139-50
    • (2006) J Opt Soc Am A Opt Image Sci Vis , vol.23 , pp. 3139-3150
    • Theer, P.1    Denk, W.2
  • 190
    • 84934437949 scopus 로고    scopus 로고
    • Two-photon imaging of capillary blood flow in olfactory bulb glomeruli
    • Tiret P, Chaigneau E, Lecoq J, Charpak S (2009) Two-photon imaging of capillary blood flow in olfactory bulb glomeruli. Methods Mol Biol 489:81-91
    • (2009) Methods Mol Biol , vol.489 , pp. 81-91
    • Tiret, P.1    Chaigneau, E.2    Lecoq, J.3    Charpak, S.4
  • 191
    • 84896994780 scopus 로고    scopus 로고
    • All-optical, in situ histology of brain tissue with ultra-short laser pulses
    • New York: Cold Spring Harbor Laboratory Press
    • Tsai PS, Blinder P, Kaufhold JP, Squier JD, Kleinfeld D (2011) All-optical, in situ histology of brain tissue with ultra-short laser pulses. In: Imaging in neuroscience and development, Vol. 2. New York: Cold Spring Harbor Laboratory Press, 437-46
    • (2011) Imaging in Neuroscience and Development , vol.2 , pp. 437-446
    • Tsai, P.S.1    Blinder, P.2    Kaufhold, J.P.3    Squier, J.D.4    Kleinfeld, D.5
  • 193
    • 70949083465 scopus 로고    scopus 로고
    • Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of cell nuclei and microvessels
    • Tsai PS, Kaufhold J, Blinder P, Friedman B, Drew P, Karten HJ, Lyden PD, Kleinfeld D (2009) Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of cell nuclei and microvessels. J Neurosci 18:14553-70
    • (2009) J Neurosci , vol.18 , pp. 14553-14557
    • Tsai, P.S.1    Kaufhold, J.2    Blinder, P.3    Friedman, B.4    Drew, P.5    Karten, H.J.6    Lyden, P.D.7    Kleinfeld, D.8
  • 194
    • 70949091050 scopus 로고    scopus 로고
    • In vivo two-photon laser scanning microscopy with concurrent plasma-mediated ablation: Principles and hardware realization
    • 2nd ed. (Frostig RD, ed), Boca Raton: CRC Press
    • Tsai PS, Kleinfeld D (2009) In vivo two-photon laser scanning microscopy with concurrent plasma-mediated ablation: principles and hardware realization. In: Methods for in vivo optical imaging 2nd ed. (Frostig RD, ed), Boca Raton: CRC Press, 59-115
    • (2009) Methods for in Vivo Optical Imaging , pp. 59-115
    • Tsai, P.S.1    Kleinfeld, D.2
  • 195
    • 0027399689 scopus 로고
    • Dexamethasone prevents cerebral infarction without affecting cerebral blood flow in neonatal rats
    • Tuor U, Simone CS, Barks JD, Post M (1993) Dexamethasone prevents cerebral infarction without affecting cerebral blood flow in neonatal rats. Stroke 24: 452-7 (Pubitemid 23070054)
    • (1993) Stroke , vol.24 , Issue.3 , pp. 452-457
    • Tuor, U.I.1    Simone, C.S.2    Barks, J.D.E.3    Post, M.4    Schielke, G.P.5
  • 197
    • 34548751156 scopus 로고    scopus 로고
    • Pial arteriolar vasomotion changes during cortical activation in rats
    • DOI 10.1016/j.neuroimage.2007.07.017, PII S1053811907006544
    • Vetri F, Menicucci D, Lapi D, Gemignani A, Colantuoni A (2007) Pial arteriolar vasomotion changes during cortical activation in rats. Neuroimage 38:25-33 (Pubitemid 47429991)
    • (2007) NeuroImage , vol.38 , Issue.1 , pp. 25-33
    • Vetri, F.1    Menicucci, D.2    Lapi, D.3    Gemignani, A.4    Colantuoni, A.5
  • 198
    • 0024852966 scopus 로고
    • Confocal laser microscopy to study microcirculation on the rat brain surface in vivo
    • DOI 10.1016/0006-8993(89)91616-8
    • Villringer A, Haberl RL, Dirnagl U, Anneser F, Verst M, Einhaupl KM (1989) Confocal laser microscopy to study microcirculation on the rat brain surface in vivo. Brain Res 504:159-60 (Pubitemid 20014058)
    • (1989) Brain Research , vol.504 , Issue.1 , pp. 159-160
    • Villringer, A.1    Haberl, R.L.2    Dirnagl, U.3    Anneser, F.4    Verst, M.5    Einhaupl, K.M.6
  • 200
    • 0021826450 scopus 로고
    • Induction of reproducible brain infarction by photochemically initiated thrombosis
    • DOI 10.1002/ana.410170513
    • Watson BD, Dietrich WD, Busto R, Wachtel MS, Ginsberg MD (1985) Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol 17:497-504 (Pubitemid 15019990)
    • (1985) Annals of Neurology , vol.17 , Issue.5 , pp. 497-504
    • Watson, B.D.1    Dietrich, W.D.2    Busto, R.3
  • 202
    • 48549087008 scopus 로고    scopus 로고
    • In vivo calcium imaging reveals functional rewiring of single somatosensory neurons after stroke
    • Winship IR, Murphy TH (2008) In vivo calcium imaging reveals functional rewiring of single somatosensory neurons after stroke. J Neurosci 28:6592-606
    • (2008) J Neurosci , vol.28 , pp. 6592-6606
    • Winship, I.R.1    Murphy, T.H.2
  • 203
    • 34249980900 scopus 로고    scopus 로고
    • Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo
    • DOI 10.1523/JNEUROSCI.4801-06.2007
    • Winship IR, Plaa N, Murphy TH (2007) Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo. J Neurosci 27:6268-72 (Pubitemid 46890012)
    • (2007) Journal of Neuroscience , vol.27 , Issue.23 , pp. 6268-6272
    • Winship, I.R.1    Plaa, N.2    Murphy, T.H.3
  • 205
    • 0037015212 scopus 로고    scopus 로고
    • Smooth muscle expression of Cre recombinase and eGFP in transgenic mice
    • Xin HB, Deng KY, Rishniw M, Ji G, Kotlikoff MI (2002) Smooth muscle expression of Cre recombinase and eGFP in transgenic mice. Physiol Genomics 10: 211-9
    • (2002) Physiol Genomics , vol.10 , pp. 211-219
    • Xin, H.B.1    Deng, K.Y.2    Rishniw, M.3    Ji, G.4    Kotlikoff, M.I.5
  • 206
    • 76649121846 scopus 로고    scopus 로고
    • Thinned-skull cranial window technique for long-termimaging of the cortex in live mice
    • Yang G, Pan F, Parkhurst CN, Grutzendler J, Gan WB (2010) Thinned-skull cranial window technique for long-termimaging of the cortex in live mice. Nat Protoc 5:201-8
    • (2010) Nat Protoc , vol.5 , pp. 201-208
    • Yang, G.1    Pan, F.2    Parkhurst, C.N.3    Grutzendler, J.4    Gan, W.B.5
  • 208
    • 20044374010 scopus 로고    scopus 로고
    • Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia
    • DOI 10.1523/JNEUROSCI.1085-05.2005
    • Zhang S, Boyd J, Delaney KR, Murphy TH (2005) Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia. J Neurosci 25:5333-8 (Pubitemid 40770912)
    • (2005) Journal of Neuroscience , vol.25 , Issue.22 , pp. 5333-5338
    • Zhang, S.1    Boyd, J.2    Delaney, K.3    Murphy, T.H.4
  • 209
    • 34249007157 scopus 로고    scopus 로고
    • Imaging the impact of cortical microcirculation on synaptic structure and sensoryevoked hemodynamic responses in vivo
    • Zhang S, Murphy TH (2007) Imaging the impact of cortical microcirculation on synaptic structure and sensoryevoked hemodynamic responses in vivo. PLoS Biol 5:e119
    • (2007) PLoS Biol , vol.5
    • Zhang, S.1    Murphy, T.H.2
  • 210
    • 38849095193 scopus 로고    scopus 로고
    • NG2 cells generate both oligodendrocytes and gray matter astrocytes
    • DOI 10.1242/dev.004895
    • Zhu X, Bergles DE, Nishiyama A (2008) NG2 cells generate both oligodendrocytes and gray matter astrocytes. Development 135:145-57 (Pubitemid 351201488)
    • (2008) Development , vol.135 , Issue.1 , pp. 145-157
    • Zhu, X.1    Bergles, D.E.2    Nishiyama, A.3
  • 211
    • 0031193324 scopus 로고    scopus 로고
    • Live astrocytes visualized by green fluorescent protein in transgenic mice
    • DOI 10.1006/dbio.1997.8601
    • Zhuo L, Sun B, Zhang CL, Fine A, Chiu SY, Messing A (1997) Live astrocytes visualized by green fluorescent protein in transgenic mice. Dev Biol 187:36-42 (Pubitemid 27359423)
    • (1997) Developmental Biology , vol.187 , Issue.1 , pp. 36-42
    • Zhuo, L.1    Sun, B.2    Zhang, C.-L.3    Fine, A.4    Chiu, S.-Y.5    Messing, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.