Two-photon imaging of capillary blood flow in olfactory bulb glomeruli

Methods in Molecular Biology

Volumn 489, Issue , 2009, Pages 81-91

  Tiret, Pascale ^a   Chaigneau, Emmanuelle ^a   Lecoq, Jérôme ^a   Charpak, Serge ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Calcium; Neuronal activity; Neurovascular coupling; Odor

Indexed keywords

EID: 84934437949     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-543-5_4     Document Type: Review

References (65)

1. Villringer, A. & Dirnagl, U. Coupling of brain activity and cerebral blood flow: Basis of functional neuroimaging. Cerebrovasc. Brain Metab Rev. 7, 240-276 (1995).
2. Magistretti, P.J., Pellerin, L., Rothman, D.L., & Shulman, R.G. Energy on demand. Science 283, 496-497 (1999).
3. Attwell, D. & Iadecola, C. The neural basis of functional brain imaging signals. Trends Neurosci. 25, 621-625 (2002).
4. Logothetis, N.K. & Pfeuffer, J. On the nature of the BOLD fMRI contrast mechanism. Magn. Reson. Imaging 22, 1517-1531 (2004).
5. Lauritzen, M. Reading vascular changes in brain imaging: Is dendritic calcium the key? Nat. Rev. Neurosci. 6, 77-85 (2005).
6. Mathiesen, C., Caesar, K., Akgoren, N., & Lauritzen, M. Modification of activity-dependent increases of cerebral blood flow by excitatory synaptic activity and spikes in rat cerebellar cortex. J. Physiol.-Lond. 512, 555-566 (1998).
7. Yang, G. & Iadecola, C. Activation of cerebellar climbing fibers increases cerebellar blood flow: Role of glutamate receptors, nitric oxide, and cGMP. Stroke 29, 499-507 (1998).
8. Nielsen, A.N. & Lauritzen, M. Coupling and uncoupling of activity-dependent increases of neuronal activity and blood flow in rat somatosensory cortex. J. Physiol.-Lond. 533, 773-785 (2001).
9. Hoffmeyer, H.W., Enager, P., Thomsen, K.J., & Lauritzen, M.J. Nonlinear neurovascular coupling in rat sensory cortex by activation of transcallosal fibers. J. Cereb. Blood Flow Metab(2006).
10. Gsell, W. et al. Differential effects of NMDA and AMPA glutamate receptors on functional magnetic resonance imaging signals and evoked neuronal activity during forepaw stimulation of the rat. J. Neurosci. 26, 8409-8416 (2006).
11. Gurden, H., Uchida, N., & Mainen, Z.F. Sensory-evoked intrinsic optical signals in the olfactory bulb are coupled to glutamate release and uptake. Neuron 52, 335-345 (2006).
12. Logothetis, N.K. The Underpinnings of the BOLD Functional Magnetic Resonance Imaging Signal. J. Neurosci. 23, 3963-3971 (2003).
13. Iadecola, C. & Nedergaard, M. Glial regulation of the cerebral microvasculature. Nat Neurosci 10, 1369-1376 (2007).
14. Zonta, M. et al. Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat. Neurosci. 6, 43-50 (2003).
15. Cauli, B. et al. Cortical GABA interneurons in neurovascular coupling: Relays for subcortical vasoactive pathways. J. Neurosci. 24, 8940-8949 (2004).
16. Mulligan, S.J. & MacVicar, B.A. Calcium transients in astrocyte endfeet cause cerebrovascular constrictions. Nature 431, 195-199 (2004).
17. Filosa, J.A., Bonev, A.D., & Nelson, M.T. Calcium dynamics in cortical astrocytes and arterioles during neurovascular coupling. Circ. Res. 95, e73-e81 (2004).
18. Metea, M.R. & Newman, E.A. Glial cells dilate and constrict blood vessels: A mechanism of neurovascular coupling. J. Neurosci. 26, 2862-2870 (2006).
19. Filosa, J.A. et al. Local potassium signaling couples neuronal activity to vasodilation in the brain. Nat. Neurosci. 9, 1397-1403 (2006).
20. Rancillac, A. et al. Glutamatergic Control of Microvascular Tone by Distinct GABA Neurons in the Cerebellum. J. Neurosci. 26, 6997-7006 (2006).
21. Vassar, R. et al. Topographic organization of sensory projections to the olfactory bulb. Cell 79, 981-991 (1994).
22. Ressler, K.J., Sullivan, S.L., & Buck, L.B. Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell 79, 1245-55 (1994).
23. Nagao, H., Yoshihara, Y., Mitsui, S., Fujisawa, H., & Mori, K. Two mirror-image sensory maps with domain organization in the mouse main olfactory bulb. Neuroreport 11, 3023-3027 (2000).
24. Yang, X. et al. Dynamic mapping at the laminar level of odor-elicited responses in rat olfactory bulb by functional MRI. Proc. Natl. Acad. Sci. U. S. A 95, 7715-7720 (1998).
25. Xu, F., Kida, I., Hyder, F., & Shulman, R.G. Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI. Proc. Natl. Acad. Sci. U. S. A 97, 10601-10606 (2000).
26. Kida, I., Xu, F., Shulman, R.G., & Hyder, F. Mapping at glomerular resolution: fMRI of rat olfactory bulb. Magn Reson. Med. 48, 570-576 (2002).
27. Schafer, J.R., Kida, I., Xu, F., Rothman, D.L., & Hyder, F. Reproducibility of odor maps by fMRI in rodents. Neuroimage. 31, 1238-1246 (2006).
28. Wachowiak, M. & Cohen, L.B. Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron 32, 723-735 (2001).
29. Spors, H., Wachowiak, M., Cohen, L.B., & Friedrich, R.W. Temporal dynamics and latency patterns of receptor neuron input to the olfactory bulb. J. Neurosci. 26, 1247-1259 (2006).
30. Wachowiak, M., Denk, W., & Friedrich, R.W. Functional organization of sensory input to the olfactory bulb glomerulus analyzed by two-photon calcium imaging. Proc Natl Acad Sci U S A 101, 9097-9102 (2004).
31. Spors, H. & Grinvald, A. Spatio-temporal dynamics of odor representations in the mammalian olfactory bulb. Neuron 34, 301-315 (2002).
32. Rubin, B.D. & Katz, L.C. Optical imaging of odorant representations in the mammalian olfactory bulb. Neuron 23, 499-511 (1999).
33. Uchida, N., Takahashi, Y.K., Tanifuji, M., & Mori, K. Odor maps in the mammalian olfactory bulb: Domain organization and odorant structural features. Nat. Neurosci. 3, 1035-1043 (2000).
34. Belluscio, L. & Katz, L.C. Symmetry, stereotypy, and topography of odorant representations in mouse olfactory bulbs. J. Neurosci. 21, 2113-2122 (2001).
35. Luo, M. & Katz, L.C. Response correlation maps of neurons in the mammalian olfactory bulb. Neuron 32, 1165-1179 (2001).
36. Meister, M. & Bonhoeffer, T. Tuning and topography in an odor map on the rat olfactory bulb. J. Neurosci. 21, 1351-1360 (2001).
37. Yuan, Q., Harley, C.W., McLean, J.H., & Knopfel, T. Optical imaging of odor preference memory in the rat olfactory bulb. J. Neurophysiol. 87, 3156-3159 (2002).
38. Imamura, K., Mataga, N., & Mori, K. Coding of odor molecules by mitral/tufted cells in rabbit olfactory bulb. I. Aliphatic compounds. J. Neurophysiol. 68, 1986-2002 (1992).
39. Katoh, K., Koshimoto, H., Tani, A., & Mori, K. Coding of odor molecules by mitral/tufted cells in rabbit olfactory bulb. II. Aromatic compounds. J. Neurophysiol. 70, 2161-2175 (1993).
40. Yokoi, M., Mori, K., & Nakanishi, S. Refinement of odor molecule tuning by dendrodendritic synaptic inhibition in the olfactory bulb. Proc Natl Acad Sci U S A 92, 3371-5 (1995).
41. Stewart, W.B., Kauer, J.S., & Shepherd, G.M. Functional organization of rat olfactory bulb analysed by the 2-deoxyglucose method. J. Comp Neurol. 185, 715-734 (1979).
42. Johnson, B.A., Woo, C.C., & Leon, M. Spatial coding of odorant features in the glomerular layer of the rat olfactory bulb. J. Comp Neurol. %20;393, 457-471 (1998).
43. Denk, W., Strickler, J.H., & Webb, W.W. Two-photon laser scanning fluorescence microscopy. Science 248, 73-76 (1990).
44. Svoboda, K., Denk, W., Kleinfeld, D., & Tank, D.W. In vivo dendritic calcium dynamics in neocortical pyramidal neurons. Nature 385, 161-165 (1997).
45. Kleinfeld, D., Mitra, P.P., Helmchen, F., & Denk, W. Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex. Proc Natl Acad Sci U S A 95, 15741-15746 (1998).
46. Charpak, S., Mertz, J., Beaurepaire, E., Moreaux, L., & Delaney, K. Odor-evoked calcium signals in dendrites of rat mitral cells. Proc Natl Acad Sci U S A 98, 1230-1234 (2001).
47. Debarbieux, F., Audinat, E., & Charpak, S. Action potential propagation in dendrites of rat mitral cells in vivo. J. Neurosci. 23, 5553-5560 (2003).
48. Jung, J.C., Mehta, A.D., Aksay, E., Stepnoski, R., & Schnitzer, M.J. In vivo mammalian brain imaging using one- and two-photon fluorescence microendoscopy. J. Neurophysiol. 92, 3121-3133 (2004).
49. Levene, M.J., Dombeck, D.A., Kasischke, K.A., Molloy, R.P., & Webb, W.W. In vivo multiphoton microscopy of deep brain tissue. J. Neurophysiol. 91, 1908-1912 (2004).
50. Gobel, W., Kerr, J.N., Nimmerjahn, A., & Helmchen, F. Miniaturized two-photon microscope based on a flexible coherent fiber bundle and a gradient-index lens objective. Opt. Lett. 29, 2521-2523 (2004).
51. Helmchen, F., Fee, M.S., Tank, D.W., & Denk, W. A miniature head-mounted two-photon microscope: High-resolution brain imaging in freely moving animals. Neuron 31, 903-912 (2001).
52. Oheim, M., Beaurepaire, E., Chaigneau, E., Mertz, J., & Charpak, S. Two-photon microscopy in brain tissue: Parameters influencing the imaging depth. J. Neurosci. Methods 111, 29-37 (2001).
53. Beaurepaire, E., Oheim, M., & Mertz, J. Ultra-deep two-photon fluorescence excitation in turbid media. Opt. Commun 188, 25-29 (2001).
54. Theer, P., Hasan, M.T., & Denk, W. Twophoton imaging to a depth of 1000 microm in living brains by use of a Ti:Al2O3 regenerative amplifier. Opt. Lett. 28, 1022-1024 (2003).
55. Rueckel, M., Mack-Bucher, J.A., & Denk, W. Adaptive wavefront correction in two-photon microscopy using coherence-gated wavefront sensing. Proc. Natl. Acad. Sci. U. S. A 103, 17137-17142 (2006).
56. Chaigneau, E., Oheim, M., Audinat, E., & Charpak, S. Two-photon imaging of capillary blood flow in olfactory bulb glomeruli. Proc Natl Acad Sci U S A 100, 13081-13086 (2003).
57. Attwell, D. & Laughlin, S.B. An energy budget for signaling in the grey matter of the brain. J. Cereb. Blood Flow Metab 21, 1133-1145 (2001).
58. Sharp, F.R., Kauer, J.S., & Shepherd, G.M. Local sites of activity-related glucose metabolism in rat olfactory bulb during olfactory stimulation. Brain Res. 98, 596-600 (1975).
59. Tsai, A.G. et al. Microvascular and tissue oxygen gradients in the rat mesentery. Proc. Natl. Acad. Sci. U. S. A 95, 6590-6595 (1998).
60. Chaigneau, E. et al. The relationship between blood flow and neuronal activity in the rodent olfactory bulb. J. Neurosci. 27, 6452-6460 (2007).
61. Diez-Garcia, J. et al. Activation of cerebellar parallel fibers monitored in transgenic mice expressing a fluorescent Ca2+ indicator protein. Eur. J. Neurosci. 22, 627-635 (2005).
62. Takano, T. et al. Astrocyte-mediated control of cerebral blood flow. Nat. Neurosci. 9, 260-267 (2005).
63. Rall, W. & Shepherd, G.M. Theoretical reconstruction of field potentials and dendrodendritic synaptic interactions in olfactory bulb. J. Neurophysiol. 31, 884-915 (1968).
64. Petzold, G.C., Albeanu, D.F., Sato, T.F., & Murthy, V.N. Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways. Neuron 58, 897-910 (2008).
65. Shepherd, G.M. & Charpak, S. The olfactory glomerulus: a model for neuro-glio-vascular biology. Neuron 58, 827-829 (2008).