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Volumn 13, Issue 1, 2010, Pages 127-132

An in vivo biosensor for neurotransmitter release and in situ receptor activity

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CALCIUM; CHLORPROMAZINE; CLOZAPINE; G PROTEIN COUPLED RECEPTOR; HALOPERIDOL; METABOTROPIC RECEPTOR; MUSCARINIC M1 RECEPTOR; NEUROTRANSMITTER; NEUROTRANSMITTER RECEPTOR; NICOTINE TARTRATE; OLANZAPINE; BENZODIAZEPINE DERIVATIVE; NEUROLEPTIC AGENT; PHOTOPROTEIN;

EID: 73949130442     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn.2469     Document Type: Article
Times cited : (103)

References (50)
  • 1
    • 33744827973 scopus 로고    scopus 로고
    • Volume, transmission and wiring transmission from cellular to molecular networks: History and perspectives
    • Agnati, L.F., et al. Volume, transmission and wiring transmission from cellular to molecular networks: history and perspectives. Acta Physiol. (Oxf.) 187, 329-344 (2006).
    • (2006) Acta Physiol. (Oxf.) , vol.187 , pp. 329-344
    • Agnati, L.F.1
  • 2
    • 0018069078 scopus 로고
    • The monoamine innervation of rat cerebral cortex: Synaptic and nonsynaptic axon terminals
    • Beaudet, A. & Descarries, L. The monoamine innervation of rat cerebral cortex: synaptic and nonsynaptic axon terminals. Neuroscience 3, 851-860 (1978).
    • (1978) Neuroscience , vol.3 , pp. 851-860
    • Beaudet, A.1    Descarries, L.2
  • 3
    • 14544286521 scopus 로고    scopus 로고
    • Building and breeding molecules to spy on cells and tumors
    • Tsien, R.Y. Building and breeding molecules to spy on cells and tumors. FEBS Lett. 579, 927-932 (2005).
    • (2005) FEBS Lett. , vol.579 , pp. 927-932
    • Tsien, R.Y.1
  • 4
    • 41949134810 scopus 로고    scopus 로고
    • Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fuorescent reporters
    • Hires, S.A., Zhu, Y. & Tsien, R.Y. Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fuorescent reporters. Proc. Natl. Acad. Sci. USA 105, 4411-4416 (2008).
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 4411-4416
    • Hires, S.A.1    Zhu, Y.2    Tsien, R.Y.3
  • 5
    • 20844449080 scopus 로고    scopus 로고
    • Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors
    • Okumoto, S. et al. Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors. Proc. Natl. Acad. Sci. USA 102, 8740-8745 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 8740-8745
    • Okumoto, S.1
  • 6
    • 0038729670 scopus 로고    scopus 로고
    • Measurement of the millisecond activation switch of G protein-coupled receptors in living cells
    • Vilardaga, J.-P., Bünemann, M., Krasel, C., Castro, M. & Lohse, M.J. Measurement of the millisecond activation switch of G protein-coupled receptors in living cells. Nat. Biotechnol. 21, 807-812 (2003).
    • (2003) Nat. Biotechnol. , vol.21 , pp. 807-812
    • Vilardaga, J.-P.1    Bünemann, M.2    Krasel, C.3    Castro, M.4    Lohse, M.J.5
  • 7
    • 0020503470 scopus 로고
    • Spontaneous release of transmitter from growth cones of embryonic neurones
    • Young, S.H. & Poo, M.M. Spontaneous release of transmitter from growth cones of embryonic neurones. Nature 305, 634-637 (1983).
    • (1983) Nature , vol.305 , pp. 634-637
    • Young, S.H.1    Poo, M.M.2
  • 8
    • 30744450905 scopus 로고    scopus 로고
    • Activity-dependent ATP-waves in the mouse neocortex are independent from astrocytic calcium waves
    • Haas, B. et al. Activity-dependent ATP-waves in the mouse neocortex are independent from astrocytic calcium waves. Cereb. Cortex 16, 237-246 (2006).
    • (2006) Cereb. Cortex , vol.16 , pp. 237-246
    • Haas, B.1
  • 9
    • 19644375284 scopus 로고
    • FLIPR: A new instrument for accurate, high throughput optical screening
    • Schroeder, K.S. & Neagle, B. FLIPR: A new instrument for accurate, high throughput optical screening. J. Biomol. Screen. 1, 75-80 (1995).
    • (1995) J. Biomol. Screen. , vol.1 , pp. 75-80
    • Schroeder, K.S.1    Neagle, B.2
  • 10
    • 0342647022 scopus 로고    scopus 로고
    • In vivo spectrometric calcium fux recordings of intrinsic Caudate-Putamen cells and transplanted IMR-32 neuroblastoma cells using miniature fber optrodes in anesthetized and awake rats and monkeys
    • Duff Davis, M. & Schmidt, J.J. In vivo spectrometric calcium fux recordings of intrinsic Caudate-Putamen cells and transplanted IMR-32 neuroblastoma cells using miniature fber optrodes in anesthetized and awake rats and monkeys. J. Neurosci. Methods 99, 9-23 (2000).
    • (2000) J. Neurosci. Methods , vol.99 , pp. 9-23
    • Duff Davis, M.1    Schmidt, J.J.2
  • 11
    • 0027937360 scopus 로고
    • Ultrastructural and morphometric features of the acetylcholine innervation in adult rat parietal cortex: An electron microscopic study in serial sections
    • Umbriaco, D., Watkins, K.C., Descarries, L., Cozzari, C. & Hartman, B.K. Ultrastructural and morphometric features of the acetylcholine innervation in adult rat parietal cortex: an electron microscopic study in serial sections. J. Comp. Neurol. 348, 351-373 (1994).
    • (1994) J. Comp. Neurol. , vol.348 , pp. 351-373
    • Umbriaco, D.1    Watkins, K.C.2    Descarries, L.3    Cozzari, C.4    Hartman, B.K.5
  • 12
    • 0030636350 scopus 로고    scopus 로고
    • Central cholinergic systems and cognition
    • Everitt, B.J. & Robbins, T.W. Central cholinergic systems and cognition. Annu. Rev. Psychol. 48, 649-684 (1997).
    • (1997) Annu. Rev. Psychol. , vol.48 , pp. 649-684
    • Everitt, B.J.1    Robbins, T.W.2
  • 13
    • 33847257743 scopus 로고    scopus 로고
    • Towards a muscarinic hypothesis of schizophrenia
    • Raedler, T.J. et al. Towards a muscarinic hypothesis of schizophrenia. Mol. Psychiatry 12, 232-246 (2007).
    • (2007) Mol. Psychiatry , vol.12 , pp. 232-246
    • Raedler, T.J.1
  • 14
    • 0025943814 scopus 로고
    • Identifcation and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specifc antibodies
    • Levey, A.I., Kitt, C.A., Simonds, W.F., Price, D.L. & Brann, M.R. Identifcation and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specifc antibodies. J. Neurosci. 11, 3218-3226 (1991).
    • (1991) J. Neurosci. , vol.11 , pp. 3218-3226
    • Levey, A.I.1    Kitt, C.A.2    Simonds, W.F.3    Price, D.L.4    Brann, M.R.5
  • 15
    • 50849123433 scopus 로고    scopus 로고
    • A genetically encoded calcium indicator for chronic in vivo two-photon imaging
    • Mank, M. et al. A genetically encoded calcium indicator for chronic in vivo two-photon imaging. Nat. Methods 5, 805-811 (2008).
    • (2008) Nat. Methods , vol.5 , pp. 805-811
    • Mank, M.1
  • 16
    • 0025342635 scopus 로고
    • Two-photon laser scanning fuorescence microscopy
    • Denk, W., Strickler, J.H. & Webb, W.W. Two-photon laser scanning fuorescence microscopy. Science 248, 73-76 (1990).
    • (1990) Science , vol.248 , pp. 73-76
    • Denk, W.1    Strickler, J.H.2    Webb, W.W.3
  • 17
    • 0026488323 scopus 로고
    • Frequency-dependent increase in cortical acetylcholine release evoked by stimulation of the nucleus basalis magnocellularis in the rat
    • Rasmusson, D.D., Clow, K. & Szerb, J.C. Frequency-dependent increase in cortical acetylcholine release evoked by stimulation of the nucleus basalis magnocellularis in the rat. Brain Res. 594, 150-154 (1992).
    • (1992) Brain Res. , vol.594 , pp. 150-154
    • Rasmusson, D.D.1    Clow, K.2    Szerb, J.C.3
  • 18
    • 0034849276 scopus 로고    scopus 로고
    • Application of in vivo microdialysis to the study of cholinergic systems
    • Day, J.C., Kornecook, T.J. & Quirion, R. Application of in vivo microdialysis to the study of cholinergic systems. Methods 23, 21-39 (2001).
    • (2001) Methods , vol.23 , pp. 21-39
    • Day, J.C.1    Kornecook, T.J.2    Quirion, R.3
  • 19
    • 0028238306 scopus 로고
    • Modifcation of neocortical acetylcholine release and electroencephalogram desynchronization due to brainstem stimulation by drugs applied to the basal forebrain
    • Rasmusson, D.D., Clow, K. & Szerb, J.C. Modifcation of neocortical acetylcholine release and electroencephalogram desynchronization due to brainstem stimulation by drugs applied to the basal forebrain. Neuroscience 60, 665-677 (1994).
    • (1994) Neuroscience , vol.60 , pp. 665-677
    • Rasmusson, D.D.1    Clow, K.2    Szerb, J.C.3
  • 20
    • 21544437422 scopus 로고    scopus 로고
    • Activation of nucleus basalis facilitates cortical control of a brainstem motor program
    • Berg, R.W., Friedman, B., Schroeder, L.F. & Kleinfeld, D. Activation of nucleus basalis facilitates cortical control of a brainstem motor program. J. Neurophysiol. 94, 699-711 (2005).
    • (2005) J. Neurophysiol. , vol.94 , pp. 699-711
    • Berg, R.W.1    Friedman, B.2    Schroeder, L.F.3    Kleinfeld, D.4
  • 21
    • 0742271350 scopus 로고    scopus 로고
    • What's atypical about atypical antipsychotic drugs?
    • Meltzer, H.Y. What's atypical about atypical antipsychotic drugs? Curr. Opin. Pharmacol. 4, 53-57 (2004).
    • (2004) Curr. Opin. Pharmacol. , vol.4 , pp. 53-57
    • Meltzer, H.Y.1
  • 22
    • 44449166578 scopus 로고    scopus 로고
    • Schizophrenia therapy: Beyond atypical antipsychotics
    • Snyder, E.M. & Murphy, M.R. Schizophrenia therapy: beyond atypical antipsychotics. Nat. Rev. Drug Discov. 7, 471-472 (2008).
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 471-472
    • Snyder, E.M.1    Murphy, M.R.2
  • 23
  • 24
    • 0036234969 scopus 로고    scopus 로고
    • Effects of atypical antipsychotics on vertebrate neuromuscular transmission
    • Nguyen, Q.T., Yang, J. & Miledi, R. Effects of atypical antipsychotics on vertebrate neuromuscular transmission. Neuropharmacology 42, 670-676 (2002).
    • (2002) Neuropharmacology , vol.42 , pp. 670-676
    • Nguyen, Q.T.1    Yang, J.2    Miledi, R.3
  • 25
    • 0031007902 scopus 로고    scopus 로고
    • Selective action of acute systemic clozapine on acetylcholine release in the rat prefrontal cortex by reference to the nucleus accumbens and striatum
    • Parada, M.A. & Hernandez, L. Selective action of acute systemic clozapine on acetylcholine release in the rat prefrontal cortex by reference to the nucleus accumbens and striatum. J. Pharmacol. Exp. Ther. 281, 582-588 (1997).
    • (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 582-588
    • Parada, M.A.1    Hernandez, L.2
  • 26
    • 0036176263 scopus 로고    scopus 로고
    • A typical but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum
    • Ichikawa, J., Dai, J., O'Laughlin, I.A., Fowler, W.L. & Meltzer, H.Y. Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum. Neuropsychopharmacology 26, 325-339 (2002).
    • (2002) Neuropsychopharmacology , vol.26 , pp. 325-339
    • Ichikawa, J.1    Dai, J.2    O'Laughlin, I.A.3    Fowler, W.L.4    Meltzer, H.Y.5
  • 27
    • 0026579901 scopus 로고
    • Antagonism by antimuscarinic and neuroleptic compounds at the fve cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells
    • Bolden, C., Cusack, B. & Richelson, E. Antagonism by antimuscarinic and neuroleptic compounds at the fve cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells. J. Pharmacol. Exp. Ther. 260, 576-580 (1992).
    • (1992) J. Pharmacol. Exp. Ther. , vol.260 , pp. 576-580
    • Bolden, C.1    Cusack, B.2    Richelson, E.3
  • 28
    • 33750628479 scopus 로고    scopus 로고
    • A model of anticholinergic activity of atypical antipsychotic medications
    • Chew, M.L. et al. A model of anticholinergic activity of atypical antipsychotic medications. Schizophr. Res. 88, 63-72 (2006).
    • (2006) Schizophr. Res. , vol.88 , pp. 63-72
    • Chew, M.L.1
  • 29
    • 16844363204 scopus 로고    scopus 로고
    • The highly effcacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: Is M1 agonism a pre-requisite for mimicking clozapine's actions
    • Davies, M.A., Compton-Toth, B.A., Hufeisen, S.J., Meltzer, H.Y. & Roth, B.L. The highly effcacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: Is M1 agonism a pre-requisite for mimicking clozapine's actions. Psychopharmacology (Berl.) 178, 451-460 (2005).
    • (2005) Psychopharmacology (Berl.) , vol.178 , pp. 451-460
    • Davies, M.A.1    Compton-Toth, B.A.2    Hufeisen, S.J.3    Meltzer, H.Y.4    Roth, B.L.5
  • 30
    • 14944342214 scopus 로고    scopus 로고
    • The role of muscarinic receptor antagonism in antipsychotic-induced hippocampal acetylcholine release
    • Johnson, D.E. et al. The role of muscarinic receptor antagonism in antipsychotic-induced hippocampal acetylcholine release. Eur. J. Pharmacol. 506, 209-219 (2005).
    • (2005) Eur. J. Pharmacol. , vol.506 , pp. 209-219
    • Johnson, D.E.1
  • 31
    • 34548348729 scopus 로고    scopus 로고
    • Molecular targets for treating cognitive dysfunction in schizophrenia
    • Gray, J.A. & Roth, B.L. Molecular targets for treating cognitive dysfunction in schizophrenia. Schizophr. Bull. 33, 1100-1119 (2007).
    • (2007) Schizophr. Bull. , vol.33 , pp. 1100-1119
    • Gray, J.A.1    Roth, B.L.2
  • 32
    • 0031809369 scopus 로고    scopus 로고
    • Pharmacological characterization of nicotinic receptor-mediated acetylcholine release in rat brain: An in vivo microdialysis study
    • Tani, Y., Saito, K., Imoto, M. & Ohno, T. Pharmacological characterization of nicotinic receptor-mediated acetylcholine release in rat brain: an in vivo microdialysis study. Eur. J. Pharmacol. 351, 181-188 (1998).
    • (1998) Eur. J. Pharmacol. , vol.351 , pp. 181-188
    • Tani, Y.1    Saito, K.2    Imoto, M.3    Ohno, T.4
  • 33
    • 0016138354 scopus 로고
    • Antischizophrenic drugs and brain cholinergic receptors. Affnity for muscarinic sites predicts extrapyramidal effects
    • Snyder, S., Greenberg, D. & Yamamura, H.I. Antischizophrenic drugs and brain cholinergic receptors. Affnity for muscarinic sites predicts extrapyramidal effects. Arch. Gen. Psychiatry 31, 58-61 (1974).
    • (1974) Arch. Gen. Psychiatry , vol.31 , pp. 58-61
    • Snyder, S.1    Greenberg, D.2    Yamamura, H.I.3
  • 34
    • 10644276245 scopus 로고    scopus 로고
    • Kinetics of G protein-coupled receptor signaling and desensitization
    • Krasel, C., Vilardaga, J.P., Bunemann, M. & Lohse, M.J. Kinetics of G protein-coupled receptor signaling and desensitization. Biochem. Soc. Trans. 32, 1029-1031 (2004).
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 1029-1031
    • Krasel, C.1    Vilardaga, J.P.2    Bunemann, M.3    Lohse, M.J.4
  • 35
    • 0032524334 scopus 로고    scopus 로고
    • Receptor subtype-specifc regulation of muscarinic acetylcholine receptor sequestration by dynamin. Distinct sequestration of m2 receptors
    • Vögler, O. et al. Receptor subtype-specifc regulation of muscarinic acetylcholine receptor sequestration by dynamin. Distinct sequestration of m2 receptors. J. Biol. Chem. 273, 12155-12160 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 12155-12160
    • Vögler, O.1
  • 37
    • 24344475560 scopus 로고    scopus 로고
    • 2+ requirement, and regulation of M current
    • 2+ requirement, and regulation of M current. J. Gen. Physiol. 126, 243-262 (2005).
    • (2005) J. Gen. Physiol. , vol.126 , pp. 243-262
    • Horowitz, L.F.1
  • 38
    • 25644446102 scopus 로고    scopus 로고
    • Insulin disrupts beta-adrenergic signaling to protein kinase A in adipocytes
    • Zhang, J., Hupfeld, C.J., Taylor, S.S., Olefsky, J.M. & Tsien, R.Y. Insulin disrupts beta-adrenergic signaling to protein kinase A in adipocytes. Nature 437, 569-573 (2005).
    • (2005) Nature , vol.437 , pp. 569-573
    • Zhang, J.1    Hupfeld, C.J.2    Taylor, S.S.3    Olefsky, J.M.4    Tsien, R.Y.5
  • 39
    • 27144434813 scopus 로고    scopus 로고
    • Techniques: Promiscuous Gα proteins in basic research and drug discovery
    • Kostenis, E., Waelbroeck, M. & Milligan, G. Techniques: promiscuous Gα proteins in basic research and drug discovery. Trends Pharmacol. Sci. 26, 595-602 (2005).
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 595-602
    • Kostenis, E.1    Waelbroeck, M.2    Milligan, G.3
  • 40
    • 0033151694 scopus 로고    scopus 로고
    • Chimeric G proteins allow a high-throughput signaling assay of Gi-coupled receptors
    • Coward, P., Chan, S.D., Wada, H.G., Humphries, G.M. & Conklin, B.R. Chimeric G proteins allow a high-throughput signaling assay of Gi-coupled receptors. Anal. Biochem. 270, 242-248 (1999).
    • (1999) Anal. Biochem. , vol.270 , pp. 242-248
    • Coward, P.1    Chan, S.D.2    Wada, H.G.3    Humphries, G.M.4    Conklin, B.R.5
  • 41
    • 11144267737 scopus 로고    scopus 로고
    • Improved monomeric red, orange and yellow fuorescent proteins derived from Discosoma sp. red fuorescent protein
    • Shaner, N.C. et al. Improved monomeric red, orange and yellow fuorescent proteins derived from Discosoma sp. red fuorescent protein. Nat. Biotechnol. 22, 1567-1572 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1567-1572
    • Shaner, N.C.1
  • 42
    • 70949091050 scopus 로고    scopus 로고
    • In vivo two-photon laser-scanning microscopy with concurrent plasma-mediated ablation: Principles and hardware realization
    • 2nd edn (ed. R.D. Frostig) CRC Press, Boca Raton
    • Tsai, P.S. & Kleinfeld, D. In vivo two-photon laser-scanning microscopy with concurrent plasma-mediated ablation: principles and hardware realization. in Methods for In vivo Optical Imaging, 2nd edn (ed. R.D. Frostig) 59-115 (CRC Press, Boca Raton, 2009).
    • (2009) Methods for in Vivo Optical Imaging , pp. 59-115
    • Tsai, P.S.1    Kleinfeld, D.2
  • 43
    • 70949093606 scopus 로고    scopus 로고
    • MPScope 2.0: A computer system for two-photon laser scanning microscopy with concurrent plasma-mediated ablation and electrophysiology
    • 2nd edn (ed. R.D. Frostig) CRC Press, Boca Raton
    • Nguyen, Q.-T., Dolnick, E.M., Driscoll, J. & Kleinfeld, D. MPScope 2.0: A computer system for two-photon laser scanning microscopy with concurrent plasma-mediated ablation and electrophysiology. in Methods for In vivo Optical Imaging 2nd edn (ed. R.D. Frostig) 117-142 (CRC Press, Boca Raton, 2009).
    • (2009) Methods for in Vivo Optical Imaging , pp. 117-142
    • Nguyen, Q.-T.1    Dolnick, E.M.2    Driscoll, J.3    Kleinfeld, D.4
  • 44
    • 61949190911 scopus 로고    scopus 로고
    • Absolute two-photon absorption spectra and two-photon brightness of orange and red fuorescent proteins
    • Drobizhev, M., Tillo, S., Makarov, N.S., Hughes, T.E. & Rebane, A. Absolute two-photon absorption spectra and two-photon brightness of orange and red fuorescent proteins. J. Phys. Chem. B 113, 855-859 (2009).
    • (2009) J. Phys. Chem. B , vol.113 , pp. 855-859
    • Drobizhev, M.1    Tillo, S.2    Makarov, N.S.3    Hughes, T.E.4    Rebane, A.5
  • 45
    • 33244478081 scopus 로고    scopus 로고
    • Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood fow after vascular occlusion
    • Schaffer, C.B. et al. Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood fow after vascular occlusion. PLoS Biol. 4, e22 (2006).
    • (2006) PLoS Biol. , vol.4
    • Schaffer, C.B.1
  • 46
    • 0027137818 scopus 로고
    • Ionic fux contributions to neocortical slow waves and nucleus basalis-mediated activation: Whole-cell recordings in vivo
    • Metherate, R. & Ashe, J.H. Ionic fux contributions to neocortical slow waves and nucleus basalis-mediated activation: whole-cell recordings in vivo. J. Neurosci. 12, 5312-5323 (1993).
    • (1993) J. Neurosci. , vol.12 , pp. 5312-5323
    • Metherate, R.1    Ashe, J.H.2
  • 47
    • 0026579276 scopus 로고
    • Morphological and neurochemical features of cultured primary skin fbroblasts of Fischer 344 rats following striatal implantation
    • Kawaja, M.D. & Gage, F.H. Morphological and neurochemical features of cultured primary skin fbroblasts of Fischer 344 rats following striatal implantation. J. Comp. Neurol. 317, 102-116 (1992).
    • (1992) J. Comp. Neurol. , vol.317 , pp. 102-116
    • Kawaja, M.D.1    Gage, F.H.2
  • 48
    • 31744448499 scopus 로고    scopus 로고
    • Targeted insult to individual subsurface cortical blood vessels using ultrashort laser pulses: Three models of stroke
    • Nishimura, N. et al. Targeted insult to individual subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke. Nat. Methods 3, 99-108 (2006).
    • (2006) Nat. Methods , vol.3 , pp. 99-108
    • Nishimura, N.1
  • 49
    • 0036201186 scopus 로고    scopus 로고
    • Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine effux in the hippocampus of the rat
    • Shirazi-Southall, S., Rodriguez, D.E. & Nomikos, G.G. Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine effux in the hippocampus of the rat. Neuropsychopharmacology 26, 583-594 (2002).
    • (2002) Neuropsychopharmacology , vol.26 , pp. 583-594
    • Shirazi-Southall, S.1    Rodriguez, D.E.2    Nomikos, G.G.3
  • 50
    • 0010045457 scopus 로고    scopus 로고
    • Bayesian curve-ftting with free-knot splines
    • DiMatteo, I., Genovese, C.R. & Kass, R.E. Bayesian curve-ftting with free-knot splines. Biometrika 88, 1055-1071 (2001).
    • (2001) Biometrika , vol.88 , pp. 1055-1071
    • Dimatteo, I.1    Genovese, C.R.2    Kass, R.E.3


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