Two-photon imaging to a depth of 1000 μm in living brains by use of a Ti:Al2O3 regenerative amplifier

Optics Letters

Volumn 28, Issue 12, 2003, Pages 1022-1024

  Theer, Patrick ^a   Hasan, Mazahir T ^a   Denk, Winfried ^a  

^a MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPLIFIERS (ELECTRONIC); BRAIN; FLUORESCENCE; PHOTONS;

TWO-PHOTON IMAGING;

IMAGING TECHNIQUES;

ALUMINUM OXIDE; DEXTRAN; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; FLUORESCEIN ISOTHIOCYANATE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GREEN FLUORESCENT PROTEIN; PHOTOPROTEIN; TITANIUM;

ANIMAL; ARTICLE; BLOOD VESSEL; BRAIN; BRAIN CIRCULATION; BRAIN CORTEX; FLUORESCENCE MICROSCOPY; HISTOLOGY; MOUSE; PERIAQUEDUCTAL GRAY MATTER; PHOTON; THREE DIMENSIONAL IMAGING; TRANSGENIC MOUSE;

ALUMINUM OXIDE; ANIMALS; BLOOD VESSELS; BRAIN; CEREBRAL CORTEX; CEREBROVASCULAR CIRCULATION; DEXTRANS; FLUORESCEIN-5-ISOTHIOCYANATE; GREEN FLUORESCENT PROTEINS; IMAGING, THREE-DIMENSIONAL; INDICATORS AND REAGENTS; LUMINESCENT PROTEINS; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; PERIAQUEDUCTAL GRAY; PHOTONS; TITANIUM;

EID: 0038648569     PISSN: 01469592     EISSN: None     Source Type: Journal    
DOI: 10.1364/OL.28.001022     Document Type: Article

References (21)

1. W. Denk, J. H. Strickler, and W. W. Webb, Science 248, 73 (1990).
2. F. Helmchen and W. Denk, Curr. Opin. Neurobiol. 12, 593 (2002).
3. W. Denk, K. R. Delaney, A. Gelperin, D. Kleinfeld, B. W. Stowbridge, D. W. Tank, and R. Yuste, J. Neurosci. Methods 54, 151 (1994).
4. K. Svoboda, F. Helmchen, W. Denk, and D. W. Tank, Nat. Neurosci. 2, 65 (1999).
5. D. Kleinfeld, P. P. Mitra, F. Helmchen, and W. Denk, Proc. Natl. Acad. Sci. USA 95, 15741 (1998).
6. K. Konig, T. W. Becker, P. Fischer, I. Riemann, and K. J. Halbhuber, Opt. Lett. 24, 113 (1999).
7. H. J. Koester, D. Baur, R. Uhl, and S. W. Hell, Biophys. J. 77, 2226 (1999).
8. A. Hopt and E. Neher, Biophys. J. 80, 2029 (2001).
9. M. Oheim, E. Beaurepaire, E. Chaigneau, J. Mertz, and S. Charpak, J. Neurosci. Methods 112, 205 (2001).
10. D. N. Fittinghoff, A. C. Millard, J. A. Squier, and M. Muller, IEEE J. Quantum Electron. 35, 479 (1999).
11. M. Muller, J. Squier, R. Wolleschensky, U. Simon, and G. J. Brakenhoff, J. Microsc. (Oxford) 191, 141 (1998).
12. E. Beaurepaire, M. Oheim, and J. Mertz, Opt. Commun. 188, 25 (2001).
13. S. H. Cho, F. X. Kartner, U. Morgner, E. P. Ippen, J. G. Fujimoto, J. E. Cunningham, and W. H. Knox, Opt. Lett. 26, 560 (2001).
14. M. Ramaswamy, M. Ulman, J. Paye, and J. G. Fujimoto, Opt. Lett. 18, 1822 (1993).
15. T. B. Norris, Opt. Lett. 17, 1009 (1992).
16. W. Denk, "Optical beam power controller using a tiltable birefringent plate," U.S. patent 6,249,379 B1 (June 19, 2001).
17. J. P. Ying, F. Liu, and R. R. Alfano, Appl. Opt. 38, 2151 (1999).
18. P. Theer and W. Denk are preparing a manuscript on the fundamental imaging-depth limit in two-photon microscopy.
19. J. W. McLean, J. D. Freeman, and R. E. Walker, Appl. Opt. 37, 4701 (1998).
20. H. E. Krestel, M. Mayford, P. H. Seeburg, and R. Sprengel, Nucleic Acids Res. 29, E39 (2001).
21. M. J. Booth, M. A. A. Neil, and T. Wilson, J. Opt. Soc. Am. A 19, 2112 (2002).