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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 14, 2012, Pages 4619-4624

Discovery and modification of sulfur-containing heterocyclic pyrazoline derivatives as potential novel class of β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitors

(9) Yang, Yu Shun a Zhang, Fei a Gao, Chao a Zhang, Yan Bin a Wang, Xiao Liang a Tang, Jian Feng a Sun, Jian a Gong, Hai Bin b Zhu, Hai Liang a

a NANJING UNIVERSITY (China)

b XUZHOU CENTRAL HOSPITAL (China)

Author keywords

Antibacterial activity; FabH; Pyrazoline; Thiazole; Thiazolidinone

Indexed keywords

BETA KETOACYLACYL CARRIER PROTEIN SYNTHASE III INHIBITOR; PROTEIN INHIBITOR; PYRAZOLINE DERIVATIVE; SULFUR; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG STRUCTURE; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; NONHUMAN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE; DRUG DISCOVERY; ENZYME INHIBITORS; HETEROCYCLIC COMPOUNDS; HYDROGEN BONDING; MICROBIAL VIABILITY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PYRAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFUR COMPOUNDS;

BACILLUS SUBTILIS; ESCHERICHIA COLI; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 84863422802 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.05.091 Document Type: Article

Times cited : (30)

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