The effect of 1,3-diaryl-[1H]-pyrazole-4-acetamides on glucose utilization in ob/ob mice

Journal of Medicinal Chemistry

Volumn 44, Issue 16, 2001, Pages 2601-2611

  Bebernitz, G R ^a   Argentieri, G ^a   Battle, B ^a   Brennan, C ^a   Balkan, B ^a,b   Burkey, B F ^a   Eckhardt, M ^a   Gao, J ^a   Kapa, P ^a   Strohschein, R J ^a   Schuster, H F ^a   Wilson, M ^a   Xu, D D ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b IDD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (1,1' BIPHENYL) 4 YL N,N'DIMETHYL 1 [3 (TRIFLUOROMETHYL)PHENYL] 1H PYRAZOLE 4 ACETAMIDE; ANTIDIABETIC AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; THIAZOLIDINE; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ABSORPTION; DRUG POTENCY; GLUCOSE UTILIZATION; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; MOUSE; MUSCLE CELL; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ACETAMIDES; ADIPOSE TISSUE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BEHAVIOR, ANIMAL; BIOLOGICAL AVAILABILITY; BLOOD GLUCOSE; CELL LINE; DIABETES MELLITUS; GLUCOSE; HYPOGLYCEMIC AGENTS; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; MUSCLE, SKELETAL; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035797357     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010032c     Document Type: Article

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