Reduced serotonin reuptake transporter (SERT) function causes insulin resistance and hepatic steatosis independent of food intake

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Chen, Xiaoning ^a   Margolis, Kara J ^b   Gershon, Michael D ^b   Schwartz, Gary J ^a   Sze, Ji Y ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SEROTONIN REUPTAKE TRANSPORTER; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; INSULIN; SEROTONIN TRANSPORTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BODY FAT; CELL EXPANSION; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE COURSE; ENZYME ACTIVITY; ENZYME REGULATION; FATTY LIVER; FOOD INTAKE; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERLEPTINEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; MALE; METABOLIC SYNDROME X; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET CELL HYPERPLASIA; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WEIGHT CONTROL; ANIMAL; BLOOD; BODY WEIGHT; C57BL MOUSE; EATING; ENZYME ACTIVATION; GENETICS; HYPERTROPHY; METABOLISM; MOUSE MUTANT; MUSCLE; MUTATION; PANCREAS ISLET; PATHOLOGY; PSYCHOLOGICAL ASPECT;

MUS;

ANIMALS; BODY WEIGHT; EATING; ENZYME ACTIVATION; FATTY LIVER; GLUCOSE INTOLERANCE; HYPERTROPHY; INSULIN; INSULIN RESISTANCE; ISLETS OF LANGERHANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEPTIN; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLES; MUTATION; OBESITY; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 84863262841     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032511     Document Type: Article

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