메뉴 건너뛰기




Volumn 18, Issue 1, 2010, Pages 137-145

Serotonin transporter deficiency increases abdominal fat in female, but not male rats

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; INSULIN; LEPTIN; SEROTONIN TRANSPORTER;

EID: 73949084789     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2009.139     Document Type: Article
Times cited : (28)

References (32)
  • 1
    • 33644674139 scopus 로고    scopus 로고
    • Gender differences in the metabolic syndrome and their role for cardiovascular disease
    • Regitz-Zagrosek V, Lehmkuhl E, Weickert MO. Gender differences in the metabolic syndrome and their role for cardiovascular disease. Clin Res Cardiol 2006;95:136-147.
    • (2006) Clin Res Cardiol , vol.95 , pp. 136-147
    • Regitz-Zagrosek, V.1    Lehmkuhl, E.2    Weickert, M.O.3
  • 2
    • 0036210682 scopus 로고    scopus 로고
    • Hypercortisolemic depression is associated with increased intra-abdominal fat
    • Weber-Hamann B, Hentschel F, Kniest A et al. Hypercortisolemic depression is associated with increased intra-abdominal fat. Psychosom Med 2002;64:274-277.
    • (2002) Psychosom Med , vol.64 , pp. 274-277
    • Weber-Hamann, B.1    Hentschel, F.2    Kniest, A.3
  • 3
    • 40949084721 scopus 로고    scopus 로고
    • A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders
    • Olivier JD, Van Der Hart MG, Van Swelm RP et al. A study in male and female 5-HT transporter knockout rats: an animal model for anxiety and depression disorders. Neuroscience 2008;152:573-584.
    • (2008) Neuroscience , vol.152 , pp. 573-584
    • Olivier, J.D.1    Van Der Hart, M.G.2    Van Swelm, R.P.3
  • 4
    • 33846448741 scopus 로고    scopus 로고
    • Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice
    • Wellman CL, Izquierdo A, Garrett JE et al. Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice. J Neurosci 2007;27:684-691.
    • (2007) J Neurosci , vol.27 , pp. 684-691
    • Wellman, C.L.1    Izquierdo, A.2    Garrett, J.E.3
  • 5
    • 51049089858 scopus 로고    scopus 로고
    • Depression and the serotonin transporter 5-HTTLPR polymorphism: A review and a hypothesis concerning gene-environment interaction
    • Brown GW, Harris TO. Depression and the serotonin transporter 5-HTTLPR polymorphism: a review and a hypothesis concerning gene-environment interaction. J Affect Disord 2008;111:1-12.
    • (2008) J Affect Disord , vol.111 , pp. 1-12
    • Brown, G.W.1    Harris, T.O.2
  • 6
    • 35548988366 scopus 로고    scopus 로고
    • Serotonin and the orchestration of energy balance
    • Tecott LH. Serotonin and the orchestration of energy balance. Cell Metab 2007;6:352-361.
    • (2007) Cell Metab , vol.6 , pp. 352-361
    • Tecott, L.H.1
  • 7
    • 33644765339 scopus 로고    scopus 로고
    • Investigation of the serotonin transporter regulatory region polymorphism in bulimia nervosa: Relationships to harm avoidance, nutritional parameters, and psychiatric comorbidity
    • Monteleone P, Santonastaso P, Mauri M et al. Investigation of the serotonin transporter regulatory region polymorphism in bulimia nervosa: relationships to harm avoidance, nutritional parameters, and psychiatric comorbidity. Psychosom Med 2006;68:99-103.
    • (2006) Psychosom Med , vol.68 , pp. 99-103
    • Monteleone, P.1    Santonastaso, P.2    Mauri, M.3
  • 8
    • 34547466155 scopus 로고    scopus 로고
    • A reciprocal interaction between food-motivated behavior and diet-induced obesity
    • la Fleur SE, Vanderschuren LJ, Luijendijk MC et al. A reciprocal interaction between food-motivated behavior and diet-induced obesity. Int J Obes (Lond) 2007;31:1286-1294.
    • (2007) Int J Obes (Lond) , vol.31 , pp. 1286-1294
    • La Fleur, S.E.1    Vanderschuren, L.J.2    Luijendijk, M.C.3
  • 9
    • 33644601589 scopus 로고    scopus 로고
    • Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis
    • Smits BM, Mudde JB, van de Belt J et al. Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis. Pharmacogenet Genomics 2006;16:159-169.
    • (2006) Pharmacogenet Genomics , vol.16 , pp. 159-169
    • Smits, B.M.1    Mudde, J.B.2    Van De Belt, J.3
  • 10
    • 34249080888 scopus 로고    scopus 로고
    • Characterization of the serotonin transporter knockout rat: A selective change in the functioning of the serotonergic system
    • Homberg JR, Olivier JD, Smits BM et al. Characterization of the serotonin transporter knockout rat: a selective change in the functioning of the serotonergic system. Neuroscience 2007;146:1662-1676.
    • (2007) Neuroscience , vol.146 , pp. 1662-1676
    • Homberg, J.R.1    Olivier, J.D.2    Smits, B.M.3
  • 11
    • 0032213142 scopus 로고    scopus 로고
    • Hypothalamic serotonin in control of eating behavior, meal size, and body weight
    • Leibowitz SF, Alexander JT. Hypothalamic serotonin in control of eating behavior, meal size, and body weight. Biol Psychiatry 1998;44:851-864.
    • (1998) Biol Psychiatry , vol.44 , pp. 851-864
    • Leibowitz, S.F.1    Alexander, J.T.2
  • 12
    • 48049122651 scopus 로고    scopus 로고
    • Stress-induced hyperthermia and basal body temperature are mediated by different 5-HT(1A) receptor populations: A study in SERT knockout rats
    • Olivier JD, Cools AR, Olivier B et al. Stress-induced hyperthermia and basal body temperature are mediated by different 5-HT(1A) receptor populations: a study in SERT knockout rats. Eur J Pharmacol 2008;590:190-197.
    • (2008) Eur J Pharmacol , vol.590 , pp. 190-197
    • Olivier, J.D.1    Cools, A.R.2    Olivier, B.3
  • 13
    • 21144448323 scopus 로고    scopus 로고
    • Visceral fat deposition and insulin sensitivity in depressed women with and without comorbid borderline personality disorder
    • Kahl KG, Bester M, Greggersen W et al. Visceral fat deposition and insulin sensitivity in depressed women with and without comorbid borderline personality disorder. Psychosom Med 2005;67:407-412.
    • (2005) Psychosom Med , vol.67 , pp. 407-412
    • Kahl, K.G.1    Bester, M.2    Greggersen, W.3
  • 14
    • 33749542744 scopus 로고    scopus 로고
    • Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies
    • Ren-Patterson RF, Cochran LW, Holmes A et al. Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cell Mol Neurobiol 2006;26:755-780.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 755-780
    • Ren-Patterson, R.F.1    Cochran, L.W.2    Holmes, A.3
  • 16
    • 33846390395 scopus 로고    scopus 로고
    • Tolerability and effectiveness of fluoxetine, metformin and sibutramine in reducing anthropometric and metabolic parameters in obese patients
    • Guimarães C, Pereira LR, Iucif Júnior N et al. Tolerability and effectiveness of fluoxetine, metformin and sibutramine in reducing anthropometric and metabolic parameters in obese patients. Arq Bras Endocrinol Metabol 2006;50:1020-1025.
    • (2006) Arq Bras Endocrinol Metabol , vol.50 , pp. 1020-1025
    • Guimarães, C.1    Pereira, L.R.2    Iucif Júnior, N.3
  • 17
    • 0034331195 scopus 로고    scopus 로고
    • Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: Gender and brain region differences
    • Li Q, Wichems C, Heils A, Lesch K P, Murphy DL. Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences. J Neurosci 2000;20:7888-7895.
    • (2000) J Neurosci , vol.20 , pp. 7888-7895
    • Li, Q.1    Wichems, C.2    Heils, A.3    Lesch, K.P.4    Murphy, D.L.5
  • 18
    • 4143131140 scopus 로고    scopus 로고
    • Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor
    • Muraki Y, Yamanaka A, Tsujino N et al. Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor. J Neurosci 2004;24:7159-7166.
    • (2004) J Neurosci , vol.24 , pp. 7159-7166
    • Muraki, Y.1    Yamanaka, A.2    Tsujino, N.3
  • 19
    • 33846246036 scopus 로고    scopus 로고
    • Serotonergic drugs: Effects on appetite expression and use for the treatment of obesity
    • Halford JC, Harrold JA, Boyland EJ, Lawton CL, Blundell JE. Serotonergic drugs: effects on appetite expression and use for the treatment of obesity. Drugs 2007;67:27-55.
    • (2007) Drugs , vol.67 , pp. 27-55
    • Halford, J.C.1    Harrold, J.A.2    Boyland, E.J.3    Lawton, C.L.4    Blundell, J.E.5
  • 20
    • 34249984987 scopus 로고    scopus 로고
    • 5-HT(2C) receptor activation inhibits appetitive and consummatory components of feeding and increases brain c-fos immunoreactivity in mice
    • Somerville EM, Horwood JM, Lee MD, Kennett GA, Clifton PG. 5-HT(2C) receptor activation inhibits appetitive and consummatory components of feeding and increases brain c-fos immunoreactivity in mice. Eur J Neurosci 2007;25:3115-3124.
    • (2007) Eur J Neurosci , vol.25 , pp. 3115-3124
    • Somerville, E.M.1    Horwood, J.M.2    Lee, M.D.3    Kennett, G.A.4    Clifton, P.G.5
  • 21
    • 34948867184 scopus 로고    scopus 로고
    • Fluvoxamine, a selective serotonin reuptake inhibitor, and 5-HT2C receptor inactivation induce appetite-suppressing effects in mice via 5-HT1B receptors
    • Nonogaki K, Nozue K, Takahashi Y et al. Fluvoxamine, a selective serotonin reuptake inhibitor, and 5-HT2C receptor inactivation induce appetite-suppressing effects in mice via 5-HT1B receptors. Int J Neuropsychopharmacol 2007;10:675-681.
    • (2007) Int J Neuropsychopharmacol , vol.10 , pp. 675-681
    • Nonogaki, K.1    Nozue, K.2    Takahashi, Y.3
  • 22
    • 0037343950 scopus 로고    scopus 로고
    • Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice
    • Li Q, Wichems CH, Ma L et al. Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice. J Neurochem 2003;84:1256-1265.
    • (2003) J Neurochem , vol.84 , pp. 1256-1265
    • Li, Q.1    Wichems, C.H.2    Ma, L.3
  • 23
    • 21244500509 scopus 로고    scopus 로고
    • 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter
    • Qu Y, Villacreses N, Murphy DL, Rapoport SI. 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter. Psychopharmacology (Berl) 2005;180:12-20.
    • (2005) Psychopharmacology (Berl) , vol.180 , pp. 12-20
    • Qu, Y.1    Villacreses, N.2    Murphy, D.L.3    Rapoport, S.I.4
  • 24
    • 59249093767 scopus 로고    scopus 로고
    • Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice
    • Shanahan NA, Holick Pierz KA, Masten VL et al. Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biol Psychiatry 2009;65:401-408.
    • (2009) Biol Psychiatry , vol.65 , pp. 401-408
    • Shanahan, N.A.1    Holick Pierz, K.A.2    Masten, V.L.3
  • 25
    • 30044439732 scopus 로고    scopus 로고
    • Effect of a triallelic functional polymorphism of the serotonin-transporter-linked promoter region on expression of serotonin transporter in the human brain
    • Parsey R V, Hastings RS, Oquendo MA et al. Effect of a triallelic functional polymorphism of the serotonin-transporter-linked promoter region on expression of serotonin transporter in the human brain. Am J Psychiatry 2006;163:48-51.
    • (2006) Am J Psychiatry , vol.163 , pp. 48-51
    • Parsey, R.V.1    Hastings, R.S.2    Oquendo, M.A.3
  • 26
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: Insights into human neurobiology
    • Murphy DL, Lesch K P. Targeting the murine serotonin transporter: insights into human neurobiology. Nat Rev Neurosci 2008;9:85-96.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.P.2
  • 27
    • 39449137183 scopus 로고    scopus 로고
    • Contribution of the functional 5-HTTLPR variant of the SLC6A4 gene to obesity risk in male adults
    • Sookoian S, Gianotti TF, Gemma C, Burgueño A, Pirola CJ. Contribution of the functional 5-HTTLPR variant of the SLC6A4 gene to obesity risk in male adults. Obesity (Silver Spring) 2008;16:488-491.
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 488-491
    • Sookoian, S.1    Gianotti, T.F.2    Gemma, C.3    Burgueño, A.4    Pirola, C.J.5
  • 28
    • 0343376123 scopus 로고    scopus 로고
    • Serotonin transporter gene-linked polymorphic region: Allele distributions in relationship to body weight and in anorexia nervosa
    • PL
    • Hinney A, Barth N, Ziegler A et al. Serotonin transporter gene-linked polymorphic region: allele distributions in relationship to body weight and in anorexia nervosa. Life Sci 1997;61: PL 295-303.
    • (1997) Life Sci , vol.61 , pp. 295-303
    • Hinney, A.1    Barth, N.2    Ziegler, A.3
  • 29
    • 59249089847 scopus 로고    scopus 로고
    • Impaired hypothalamic-pituitary-adrenal axis and its feedback regulation in serotonin transporter knockout mice
    • Jiang X, Wang J, Luo T, Li Q. Impaired hypothalamic-pituitary-adrenal axis and its feedback regulation in serotonin transporter knockout mice. Psychoneuroendocrinology 2009;34:317-331.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 317-331
    • Jiang, X.1    Wang, J.2    Luo, T.3    Li, Q.4
  • 30
    • 34147106946 scopus 로고    scopus 로고
    • Glucocorticoids, the etiology of obesity and the metabolic syndrome
    • Dallman M F, Akana S F, Pecoraro NC et al. Glucocorticoids, the etiology of obesity and the metabolic syndrome. Curr Alzheimer Res 2007;4: 199-204.
    • (2007) Curr Alzheimer Res , vol.4 , pp. 199-204
    • Dallman, M.F.1    Akana, S.F.2    Pecoraro, N.C.3
  • 31
    • 34548314067 scopus 로고    scopus 로고
    • Long story short: The serotonin transporter in emotion regulation and social cognition
    • Canli T, Lesch K P. Long story short: the serotonin transporter in emotion regulation and social cognition. Nat Neurosci 2007;10: 1103-1109.
    • (2007) Nat Neurosci , vol.10 , pp. 1103-1109
    • Canli, T.1    Lesch, K.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.