C-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16 INK4a expression

Nature Cell Biology

Volumn 14, Issue 7, 2012, Pages 727-737

  Kua, Hui Yi ^a,b   Liu, Huijuan ^a   Leong, Wai Fook ^b   Li, Lili ^a   Jia, Deyong ^a   Ma, Gang ^a   Hu, Yuanyu ^b   Wang, Xueying ^c   Chau, Jenny F L ^c   Chen, Ye Guang ^b   Mishina, Yuji ^d   Boast, Sharon ^e   Yeh, James ^f,h   Xia, Li ^a   Chen, Guo Qiang ^g   He, Lin ^a   Goff, Stephen P ^f   Li, Baojie ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d TSINGHUA UNIVERSITY   (China)

^e UNIVERSITY OF MICHIGAN   (United States)

^f Columbia University ^*  (United States)

^g SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^h UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2A; INHIBITOR OF DIFFERENTIATION 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYCLIN DEPENDENT KINASE INHIBITOR 2A GENE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION REGULATION; GENE MUTATION; GENE TARGETING; INHIBITOR OF DIFFERENTIATION 1 GENE; MOLECULAR INTERACTION; MOUSE; NEWBORN; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; SIGNAL TRANSDUCTION; STEM CELL EXPANSION; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BONE MORPHOGENETIC PROTEINS; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; ENZYME ACTIVATION; GENOTYPE; INHIBITOR OF DIFFERENTIATION PROTEIN 1; MAP KINASE KINASE KINASES; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOLECULAR SEQUENCE DATA; OSTEOBLASTS; PHENOTYPE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-ABL; SIGNAL TRANSDUCTION; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TIME FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84863222584     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2528     Document Type: Article

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