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Volumn 148, Issue 4, 2012, Pages 690-701

Spt4 is selectively required for transcription of extended trinucleotide repeats

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; MESSENGER RNA; POLYGLUTAMINE; TRANSCRIPTION ELONGATION FACTOR; TRANSCRIPTION ELONGATION FACTOR SPT4; UNCLASSIFIED DRUG;

EID: 84863160228     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2011.12.032     Document Type: Article
Times cited : (83)

References (67)
  • 2
    • 79551659526 scopus 로고    scopus 로고
    • Anchoring nascent RNA to the DNA template could interfere with transcription
    • B.P. Belotserkovskii, and P.C. Hanawalt Anchoring nascent RNA to the DNA template could interfere with transcription Biophys. J. 100 2011 675 684
    • (2011) Biophys. J. , vol.100 , pp. 675-684
    • Belotserkovskii, B.P.1    Hanawalt, P.C.2
  • 3
    • 0035875668 scopus 로고    scopus 로고
    • Cell signaling can direct either binary or graded transcriptional responses
    • DOI 10.1093/emboj/20.12.3167
    • S.R. Biggar, and G.R. Crabtree Cell signaling can direct either binary or graded transcriptional responses EMBO J. 20 2001 3167 3176 (Pubitemid 32612004)
    • (2001) EMBO Journal , vol.20 , Issue.12 , pp. 3167-3176
    • Biggar, S.R.1    Crabtree, G.R.2
  • 4
    • 0141926491 scopus 로고    scopus 로고
    • Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: A potential mechanism for loss of huntingtin function in Huntington's disease
    • DOI 10.1074/jbc.M303354200
    • A. Busch, S. Engemann, R. Lurz, H. Okazawa, H. Lehrach, and E.E. Wanker Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease J. Biol. Chem. 278 2003 41452 41461 (Pubitemid 37280974)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.42 , pp. 41452-41461
    • Busch, A.1    Engemann, S.2    Lurz, R.3    Okazawa, H.4    Lehrach, H.5    Wanker, E.E.6
  • 5
    • 0034050798 scopus 로고    scopus 로고
    • Yeast heterochromatin is a dynamic structure that requires silencers continuously
    • T.H. Cheng, and M.R. Gartenberg Yeast heterochromatin is a dynamic structure that requires silencers continuously Genes Dev. 14 2000 452 463 (Pubitemid 30131890)
    • (2000) Genes and Development , vol.14 , Issue.4 , pp. 452-463
    • Cheng, T.-H.1    Gartenberg, M.R.2
  • 6
    • 58849107237 scopus 로고    scopus 로고
    • Transcriptome content and dynamics at single-nucleotide resolution
    • N. Cloonan, and S.M. Grimmond Transcriptome content and dynamics at single-nucleotide resolution Genome Biol. 9 2008 234
    • (2008) Genome Biol. , vol.9 , pp. 234
    • Cloonan, N.1    Grimmond, S.M.2
  • 7
    • 18544410106 scopus 로고    scopus 로고
    • Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
    • DOI 10.1016/S0092-8674(00)80513-9
    • S.W. Davies, M. Turmaine, B.A. Cozens, M. DiFiglia, A.H. Sharp, C.A. Ross, E. Scherzinger, E.E. Wanker, L. Mangiarini, and G.P. Bates Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation Cell 90 1997 537 548 (Pubitemid 27347243)
    • (1997) Cell , vol.90 , Issue.3 , pp. 537-548
    • Davies, S.W.1    Turmaine, M.2    Cozens, B.A.3    DiFiglia, M.4    Sharp, A.H.5    Ross, C.A.6    Scherzinger, E.7    Wanker, E.E.8    Mangiarini, L.9    Bates, G.P.10
  • 8
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
    • DOI 10.1126/science.277.5334.1990
    • M. DiFiglia, E. Sapp, K.O. Chase, S.W. Davies, G.P. Bates, J.P. Vonsattel, and N. Aronin Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain Science 277 1997 1990 1993 (Pubitemid 27449140)
    • (1997) Science , vol.277 , Issue.5334 , pp. 1990-1993
    • DiFiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.P.6    Aronin, N.7
  • 9
    • 0033757718 scopus 로고    scopus 로고
    • Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
    • I. Dragatsis, M.S. Levine, and S. Zeitlin Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice Nat. Genet. 26 2000 300 306
    • (2000) Nat. Genet. , vol.26 , pp. 300-306
    • Dragatsis, I.1    Levine, M.S.2    Zeitlin, S.3
  • 12
    • 34548775695 scopus 로고    scopus 로고
    • A persistent RNA·DNA hybrid formed by transcription of the Friedreich ataxia triplet repeat in live bacteria, and by T7 RNAP in vitro
    • DOI 10.1093/nar/gkm589
    • E. Grabczyk, M. Mancuso, and M.C. Sammarco A persistent RNA.DNA hybrid formed by transcription of the Friedreich ataxia triplet repeat in live bacteria, and by T7 RNAP in vitro Nucleic Acids Res. 35 2007 5351 5359 (Pubitemid 47423909)
    • (2007) Nucleic Acids Research , vol.35 , Issue.16 , pp. 5351-5359
    • Grabczyk, E.1    Mancuso, M.2    Sammarco, M.C.3
  • 13
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group
    • Group, H.s.D.C.R.
    • Group, H.s.D.C.R. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group Cell 72 1993 971 983
    • (1993) Cell , vol.72 , pp. 971-983
  • 14
    • 55249117324 scopus 로고    scopus 로고
    • Core structure of the yeast spt4-spt5 complex: A conserved module for regulation of transcription elongation
    • M. Guo, F. Xu, J. Yamada, T. Egelhofer, Y. Gao, G.A. Hartzog, M. Teng, and L. Niu Core structure of the yeast spt4-spt5 complex: a conserved module for regulation of transcription elongation Structure 16 2008 1649 1658
    • (2008) Structure , vol.16 , pp. 1649-1658
    • Guo, M.1    Xu, F.2    Yamada, J.3    Egelhofer, T.4    Gao, Y.5    Hartzog, G.A.6    Teng, M.7    Niu, L.8
  • 16
    • 49549096453 scopus 로고    scopus 로고
    • Polyglutamine gene function and dysfunction in the ageing brain
    • S. Hands, C. Sinadinos, and A. Wyttenbach Polyglutamine gene function and dysfunction in the ageing brain Biochim. Biophys. Acta 1779 2008 507 521
    • (2008) Biochim. Biophys. Acta , vol.1779 , pp. 507-521
    • Hands, S.1    Sinadinos, C.2    Wyttenbach, A.3
  • 17
    • 0029896450 scopus 로고    scopus 로고
    • Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae
    • G.A. Hartzog, M.A. Basrai, S.L. Ricupero-Hovasse, P. Hieter, and F. Winston Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae Mol. Cell. Biol. 16 1996 2848 2856 (Pubitemid 26161289)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.6 , pp. 2848-2856
    • Hartzog, G.A.1    Basrai, M.A.2    Ricupero-Hovasse, S.L.3    Hieter, P.4    Winston, F.5
  • 21
    • 0000773895 scopus 로고
    • Regulation of amino acid and nucleotide biosynthesis in yeast
    • E.W. Jones, J.R. Broach, Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
    • E.W. Jones, and G.R. Fink Regulation of amino acid and nucleotide biosynthesis in yeast E.W. Jones, J.R. Broach, The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression 1982 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY 181 299
    • (1982) The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression , pp. 181-299
    • Jones, E.W.1    Fink, G.R.2
  • 23
    • 0029910940 scopus 로고    scopus 로고
    • In vitro transcription of a poly(dA).poly(dT)-containing sequence is inhibited by interaction between the template and its transcripts
    • DOI 10.1093/nar/24.22.4577
    • R. Kiyama, and M. Oishi In vitro transcription of a poly(dA) x poly(dT)-containing sequence is inhibited by interaction between the template and its transcripts Nucleic Acids Res. 24 1996 4577 4583 (Pubitemid 26388648)
    • (1996) Nucleic Acids Research , vol.24 , Issue.22 , pp. 4577-4583
    • Kiyama, R.1    Oishi, M.2
  • 25
    • 0034652127 scopus 로고    scopus 로고
    • Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins
    • DOI 10.1073/pnas.97.4.1589
    • S. Krobitsch, and S. Lindquist Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins Proc. Natl. Acad. Sci. USA 97 2000 1589 1594 (Pubitemid 30118486)
    • (2000) Proceedings of the National Academy of Sciences of the United States of America , vol.97 , Issue.4 , pp. 1589-1594
    • Krobitsch, S.1    Lindquist, S.2
  • 26
    • 0242718930 scopus 로고    scopus 로고
    • Trinucleotide repeat instability: A hairpin curve at the crossroads of replication, recombination, and repair
    • DOI 10.1159/000072836
    • B.A. Lenzmeier, and C.H. Freudenreich Trinucleotide repeat instability: a hairpin curve at the crossroads of replication, recombination, and repair Cytogenet. Genome Res. 100 2003 7 24 (Pubitemid 37467788)
    • (2003) Cytogenetic and Genome Research , vol.100 , Issue.1-4 , pp. 7-24
    • Lenzmeier, B.A.1    Freudenreich, C.H.2
  • 27
    • 0034426013 scopus 로고    scopus 로고
    • Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity
    • DOI 10.1038/78054
    • H. Li, S.H. Li, H. Johnston, P.F. Shelbourne, and X.J. Li Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity Nat. Genet. 25 2000 385 389 (Pubitemid 32983427)
    • (2000) Nature Genetics , vol.25 , Issue.4 , pp. 385-389
    • Li, H.1    Li, S.-H.2    Johnston, H.3    Shelbourne, P.F.4    Li, X.-J.5
  • 28
    • 77749271119 scopus 로고    scopus 로고
    • Macromolecular drug transport into the brain using targeted therapy
    • J. Lichota, T. Skjorringe, L.B. Thomsen, and T. Moos Macromolecular drug transport into the brain using targeted therapy J. Neurochem. 113 2010 1 13
    • (2010) J. Neurochem. , vol.113 , pp. 1-13
    • Lichota, J.1    Skjorringe, T.2    Thomsen, L.B.3    Moos, T.4
  • 31
    • 0027523232 scopus 로고
    • Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae
    • E.A. Malone, J.S. Fassler, and F. Winston Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae Mol. Gen. Genet. 237 1993 449 459 (Pubitemid 23080518)
    • (1993) Molecular and General Genetics , vol.237 , Issue.3 , pp. 449-459
    • Malone, E.A.1    Fassler, J.S.2    Winston, F.3
  • 33
    • 79953779997 scopus 로고    scopus 로고
    • Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity
    • F.W. Martinez-Rucobo, S. Sainsbury, A.C. Cheung, and P. Cramer Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity EMBO J. 30 2011 1302 1310
    • (2011) EMBO J. , vol.30 , pp. 1302-1310
    • Martinez-Rucobo, F.W.1    Sainsbury, S.2    Cheung, A.C.3    Cramer, P.4
  • 34
    • 15244358670 scopus 로고    scopus 로고
    • Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo
    • DOI 10.1016/j.molcel.2005.02.017
    • P.B. Mason, and K. Struhl Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo Mol. Cell 17 2005 831 840 (Pubitemid 40386944)
    • (2005) Molecular Cell , vol.17 , Issue.6 , pp. 831-840
    • Mason, P.B.1    Struhl, K.2
  • 35
    • 0037053566 scopus 로고    scopus 로고
    • Huntingtin toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1
    • DOI 10.1083/jcb.200112104
    • A.B. Meriin, X. Zhang, X. He, G.P. Newnam, Y.O. Chernoff, and M.Y. Sherman Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1 J. Cell Biol. 157 2002 997 1004 (Pubitemid 34839774)
    • (2002) Journal of Cell Biology , vol.157 , Issue.6 , pp. 997-1004
    • Meriin, A.B.1    Zhang, X.2    He, X.3    Newnam, G.P.4    Chernoff, Y.O.5    Sherman, M.Y.6
  • 36
    • 75949115042 scopus 로고    scopus 로고
    • RNA-Seq: A method for comprehensive transcriptome analysis
    • Chapter 4, Unit 4 11, 11-13
    • U. Nagalakshmi, K. Waern, and M. Snyder RNA-Seq: a method for comprehensive transcriptome analysis Curr. Protoc. Mol. Biol. 2010 Chapter 4, Unit 4 11, 11-13
    • (2010) Curr. Protoc. Mol. Biol.
    • Nagalakshmi, U.1    Waern, K.2    Snyder, M.3
  • 40
    • 0032500666 scopus 로고    scopus 로고
    • Transcriptional properties of RNA polymerase II within triplet repeat- containing DNA from the human myotonic dystrophy and fragile X loci
    • DOI 10.1074/jbc.273.41.26998
    • M.A. Parsons, R.R. Sinden, and M.G. Izban Transcriptional properties of RNA polymerase II within triplet repeat-containing DNA from the human myotonic dystrophy and fragile X loci J. Biol. Chem. 273 1998 26998 27008 (Pubitemid 28471723)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.41 , pp. 26998-27008
    • Parsons, M.A.1    Sinden, R.R.2    Izban, M.G.3
  • 43
    • 0037415686 scopus 로고    scopus 로고
    • Molecular evidence for a positive role of Spt4 in transcription elongation
    • DOI 10.1093/emboj/cdg047
    • A.G. Rondon, M. Garcia-Rubio, S. Gonzalez-Barrera, and A. Aguilera Molecular evidence for a positive role of Spt4 in transcription elongation EMBO J. 22 2003 612 620 (Pubitemid 36193605)
    • (2003) EMBO Journal , vol.22 , Issue.3 , pp. 612-620
    • Rondon, A.G.1    Garcia-Rubio, M.2    Gonzalez-Barrera, S.3    Aguilera, A.4
  • 44
    • 0037194897 scopus 로고    scopus 로고
    • Polyglutamine pathogenesis: Emergence of unifying mechanisms for Huntington's disease and related disorders
    • C.A. Ross Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders Neuron 35 2002 819 822
    • (2002) Neuron , vol.35 , pp. 819-822
    • Ross, C.A.1
  • 45
    • 66349101604 scopus 로고    scopus 로고
    • G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafter
    • D. Roy, and M.R. Lieber G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafter Mol. Cell. Biol. 29 2009 3124 3133
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 3124-3133
    • Roy, D.1    Lieber, M.R.2
  • 46
    • 80053215162 scopus 로고    scopus 로고
    • DNA slip-outs cause RNA polymerase II arrest in vitro: Potential implications for genetic instability
    • V. Salinas-Rios, B.P. Belotserkovskii, and P.C. Hanawalt DNA slip-outs cause RNA polymerase II arrest in vitro: potential implications for genetic instability Nucleic Acids Res. 39 2011 7444 7454
    • (2011) Nucleic Acids Res. , vol.39 , pp. 7444-7454
    • Salinas-Rios, V.1    Belotserkovskii, B.P.2    Hanawalt, P.C.3
  • 49
    • 77958487260 scopus 로고    scopus 로고
    • Cellular strategies for controlling protein aggregation
    • J. Tydemers, A. Mogk, and B. Bukau Cellular strategies for controlling protein aggregation Nat. Rev. Mol. Cell Biol. 11 2010 777 788
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 777-788
    • Tydemers, J.1    Mogk, A.2    Bukau, B.3
  • 50
    • 47549105506 scopus 로고    scopus 로고
    • Identification and allele-specific silencing of the mutant huntingtin allele in Huntington's disease patient-derived fibroblasts
    • P.H. van Bilsen, L. Jaspers, M.S. Lombardi, J.C. Odekerken, E.N. Burright, and W.F. Kaemmerer Identification and allele-specific silencing of the mutant huntingtin allele in Huntington's disease patient-derived fibroblasts Hum. Gene Ther. 19 2008 710 719
    • (2008) Hum. Gene Ther. , vol.19 , pp. 710-719
    • Van Bilsen, P.H.1    Jaspers, L.2    Lombardi, M.S.3    Odekerken, J.C.4    Burright, E.N.5    Kaemmerer, W.F.6
  • 51
    • 19744380273 scopus 로고    scopus 로고
    • Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease
    • DOI 10.1093/hmg/ddi147
    • J.M. Van Raamsdonk, J. Pearson, D.A. Rogers, N. Bissada, A.W. Vogl, M.R. Hayden, and B.R. Leavitt Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease Hum. Mol. Genet. 14 2005 1379 1392 (Pubitemid 40744495)
    • (2005) Human Molecular Genetics , vol.14 , Issue.10 , pp. 1379-1392
    • Van Raamsdonk, J.M.1    Pearson, J.2    Rogers, D.A.3    Bissada, N.4    Vogl, A.W.5    Hayden, M.R.6    Leavitt, B.R.7
  • 55
    • 73849136441 scopus 로고    scopus 로고
    • Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface
    • S. Wenzel, B.M. Martins, P. Rosch, and B.M. Wohrl Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface Biochem. J. 425 2010 373 380
    • (2010) Biochem. J. , vol.425 , pp. 373-380
    • Wenzel, S.1    Martins, B.M.2    Rosch, P.3    Wohrl, B.M.4
  • 56
    • 0021152709 scopus 로고
    • Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae
    • F. Winston, D.T. Chaleff, B. Valent, and G.R. Fink Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae Genetics 107 1984 179 197 (Pubitemid 14079516)
    • (1984) Genetics , vol.107 , Issue.2 , pp. 179-197
    • Winston, F.1    Chaleff, D.T.2    Valent, B.3    Fink, G.R.4
  • 57
    • 80052716635 scopus 로고    scopus 로고
    • Cellular toxicity of expanded RNA repeats: Focus on RNA foci
    • M. Wojciechowska, and W.J. Krzyzosiak Cellular toxicity of expanded RNA repeats: focus on RNA foci Hum. Mol. Genet. 20 2011 3811 3821
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 3811-3821
    • Wojciechowska, M.1    Krzyzosiak, W.J.2
  • 58
    • 55449110096 scopus 로고    scopus 로고
    • Analysis of a Splice Array Experiment Elucidates Roles of Chromatin Elongation Factor Spt4-5 in Splicing
    • Y. Xiao, Y.H. Yang, T.A. Burckin, L. Shiue, G.A. Hartzog, and M.R. Segal Analysis of a Splice Array Experiment Elucidates Roles of Chromatin Elongation Factor Spt4-5 in Splicing PLoS Comput. Biol. 1 2005 e39
    • (2005) PLoS Comput. Biol. , vol.1 , pp. 39
    • Xiao, Y.1    Yang, Y.H.2    Burckin, T.A.3    Shiue, L.4    Hartzog, G.A.5    Segal, M.R.6
  • 59
    • 79953762028 scopus 로고    scopus 로고
    • Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy
    • Z. Yu, X. Teng, and N.M. Bonini Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy PLoS Genet. 7 2011 e1001340
    • (2011) PLoS Genet. , vol.7 , pp. 1001340
    • Yu, Z.1    Teng, X.2    Bonini, N.M.3
  • 60
    • 57249086448 scopus 로고    scopus 로고
    • Allele-specific silencing of mutant Huntington's disease gene
    • Y. Zhang, J. Engelman, and R.M. Friedlander Allele-specific silencing of mutant Huntington's disease gene J. Neurochem. 108 2009 82 90
    • (2009) J. Neurochem. , vol.108 , pp. 82-90
    • Zhang, Y.1    Engelman, J.2    Friedlander, R.M.3
  • 61
    • 0034094873 scopus 로고    scopus 로고
    • Glutamine repeats and neurodegeneration
    • DOI 10.1146/annurev.neuro.23.1.217
    • H.Y. Zoghbi, and H.T. Orr Glutamine repeats and neurodegeneration Annu. Rev. Neurosci. 23 2000 217 247 (Pubitemid 30350043)
    • (2000) Annual Review of Neuroscience , vol.23 , pp. 217-247
    • Zoghbi, H.Y.1    Orr, H.T.2
  • 62
    • 77953140497 scopus 로고    scopus 로고
    • Fluorescence lifetime dynamics of enhanced green fluorescent protein in protein aggregates with expanded polyglutamine
    • Ghukasyan, V., Hsu, C.C., Liu, C.R., Kao, F.J., and Cheng, T.H. (2010). Fluorescence lifetime dynamics of enhanced green fluorescent protein in protein aggregates with expanded polyglutamine. J. Biomed. Opt. 15, 016008.
    • (2010) J. Biomed. Opt. , vol.15 , pp. 016008
    • Ghukasyan, V.1    Hsu, C.C.2    Liu, C.R.3    Kao, F.J.4    Cheng, T.H.5
  • 63
    • 33745622658 scopus 로고    scopus 로고
    • Transformation of yeast by infectious prion particles
    • King, C.Y., Wang, H.L., and Chang, H.Y. (2006). Transformation of yeast by infectious prion particles. Methods 39, 68-71.
    • (2006) Methods , vol.39 , pp. 68-71
    • King, C.Y.1    Wang, H.L.2    Chang, H.Y.3
  • 64
    • 0037053566 scopus 로고    scopus 로고
    • Huntingtin toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1
    • DOI 10.1083/jcb.200112104
    • Meriin, A.B., Zhang, X., He, X., Newnam, G.P., Chernoff, Y.O., and Sherman, M.Y. (2002). Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1. J. Cell Biol. 157, 997-1004. (Pubitemid 34839774)
    • (2002) Journal of Cell Biology , vol.157 , Issue.6 , pp. 997-1004
    • Meriin, A.B.1    Zhang, X.2    He, X.3    Newnam, G.P.4    Chernoff, Y.O.5    Sherman, M.Y.6
  • 65
    • 46249106990 scopus 로고    scopus 로고
    • Mapping and quantifying mammalian transcriptomes by RNA-Seq
    • DOI 10.1038/nmeth.1226, PII NMETH.1226
    • Mortazavi, A., Williams, B.A., McCue, K., Schaeffer, L., and Wold, B. (2008). Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat. Methods 5, 621-628. (Pubitemid 351911867)
    • (2008) Nature Methods , vol.5 , Issue.7 , pp. 621-628
    • Mortazavi, A.1    Williams, B.A.2    McCue, K.3    Schaeffer, L.4    Wold, B.5
  • 66
    • 0035692614 scopus 로고    scopus 로고
    • Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance
    • Scholes, D.T., Banerjee, M., Bowen, B., and Curcio, M.J. (2001). Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159, 1449-1465. (Pubitemid 34087588)
    • (2001) Genetics , vol.159 , Issue.4 , pp. 1449-1465
    • Scholes, D.T.1    Banerjee, M.2    Bowen, B.3    Curcio, M.J.4


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