Allele-specific silencing of mutant Huntington's disease gene

Journal of Neurochemistry

Volumn 108, Issue 1, 2009, Pages 82-90

  Zhang, Yu ^a   Engelman, Joshua ^a   Friedlander, Robert M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Allele specific; Huntington's disease; Polymorphism; siRNA

Indexed keywords

CASPASE 3; HUNTINGTIN; SMALL INTERFERING RNA;

ALLELE; ARTICLE; CODON; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME ACTIVATION; FIBROBLAST; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; WILD TYPE;

CASPASE 3; CELL DEATH; CELL LINE, TRANSFORMED; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; LUCIFERASES; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; RNA, MESSENGER; RNA, SMALL INTERFERING; SEQUENCE DELETION; TRANSFECTION; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 57249086448     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05734.x     Document Type: Article

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