Silencing USP22 by asymmetric structure of interfering RNA inhibits proliferation and induces cell cycle arrest in bladder cancer cells

Molecular and Cellular Biochemistry

Volumn 346, Issue 1-2, 2011, Pages 11-21

  Lv, Lei ^a   Xiao, Xing Yuan ^a   Gu, Zhao Hui ^a   Zeng, Fu Qing ^a   Huang, Lu Qi ^a   Jiang, Guo Song ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Asymmetric interfering RNA (aiRNA); Bladder cancer; Cell growth; Ubiquitin specific peptidase 22 (USP22)

Indexed keywords

ASYMMETRIC INTERFERING RNA; CYCLIN E; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; REGULATOR PROTEIN; RNA DERIVATIVE; SMALL INTERFERING RNA; UBIQUITIN SPECIFIC PEPTIDASE 22; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG POTENCY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CELL LINE, TUMOR; DNA PRIMERS; GENE SILENCING; HUMANS; MALE; MICE; MICE, INBRED BALB C; POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; THIOLESTER HYDROLASES; URINARY BLADDER NEOPLASMS;

MUS;

EID: 78751616954     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0585-4     Document Type: Article

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