l-DOPA-induced neurotoxicity is reduced by the activation of the PI3K signaling pathway

Toxicology

Volumn 265, Issue 3, 2009, Pages 80-86

  Park, Hyun Hee ^a   Lee, Kyu Yong ^a   Kim, Seung Hyun ^a   Lee, Young Joo ^a   Koh, Seong Ho ^a  

^a Hanyang University College of Medicine   (South Korea)

Author keywords

l DOPA; Neurotoxicity; Phosphatidylinositol 3 kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYTOCHROME C; GLYCOGEN SYNTHASE KINASE 3BETA; HEAT SHOCK TRANSCRIPTION FACTOR 1; LEVODOPA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SERINE;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RAT; SIGNAL TRANSDUCTION; TOXICOKINETICS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL SURVIVAL; COLORING AGENTS; CULTURE MEDIA, SERUM-FREE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; FLUORESCENT DYES; INDOLES; LEVODOPA; NEURONS; PC12 CELLS; RATS; SIGNAL TRANSDUCTION; SINCALIDE; TRYPAN BLUE;

EID: 71749104937     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.09.011     Document Type: Article

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