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Volumn 1443, Issue , 2012, Pages 75-88

Cellular consequences of the expression of Alzheimer's disease-causing presenilin 1 mutations in human neuroblastoma (SH-SY5Y) cells

Author keywords

Alzheimer's disease; Amyloid mitochondria; Ca 2 + homeostasis; S170F PS1 mutation; SH SY5Y

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; CALCIUM; PRESENILIN 1;

EID: 84862829053     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.12.061     Document Type: Article
Times cited : (7)

References (47)
  • 2
    • 25444474703 scopus 로고    scopus 로고
    • Mitochondria take center stage in aging and neurodegeneration
    • DOI 10.1002/ana.20624
    • M.F. Beal Mitochondria take center stage in aging and neurodegeneration Ann. Neurol. 58 2005 495 505 (Pubitemid 41377212)
    • (2005) Annals of Neurology , vol.58 , Issue.4 , pp. 495-505
    • Beal, M.F.1
  • 3
    • 0023499666 scopus 로고
    • Photobleaching of fura-2 and its effect on determination of calcium concentrations
    • P.L. Becker, and F.S. Fay Photobleaching of fura-2 and its effect on determination of calcium concentrations Am. J. Physiol. 253 1987 C613 C618
    • (1987) Am. J. Physiol. , vol.253
    • Becker, P.L.1    Fay, F.S.2
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principal of protein-dye binding
    • M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principal of protein-dye binding Anal. Biochem. 72 1976 248 254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 0036403832 scopus 로고    scopus 로고
    • β-Amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons
    • DOI 10.1006/nbdi.2002.0516
    • C.S. Casley, J.M. Land, M.A. Sharpe, J.B. Clark, M.R. Duchen, and L. Canevari Beta-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons Neurobiol. Dis. 10 2002 258 267 (Pubitemid 35217579)
    • (2002) Neurobiology of Disease , vol.10 , Issue.3 , pp. 258-267
    • Casley, C.S.1    Land, J.M.2    Sharpe, M.A.3    Clark, J.B.4    Duchen, M.R.5    Canevari, L.6
  • 6
    • 57649171115 scopus 로고    scopus 로고
    • Mitochondrial approaches for neuroprotection
    • R.K. Chaturvedi, and M.F. Beal Mitochondrial approaches for neuroprotection Ann. N. Y. Acad. Sci. 1147 2008 395 412
    • (2008) Ann. N. Y. Acad. Sci. , vol.1147 , pp. 395-412
    • Chaturvedi, R.K.1    Beal, M.F.2
  • 8
    • 33947201115 scopus 로고    scopus 로고
    • Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease
    • DOI 10.1038/sj.embor.7400897, PII 7400897
    • B. De Strooper Loss-of-function presenilin mutations in Alzheimer disease. Talking point on the role of presenilin mutations in Alzheimer disease EMBO Rep. 8 2007 141 146 (Pubitemid 46420841)
    • (2007) EMBO Reports , vol.8 , Issue.2 , pp. 141-146
    • De Strooper, B.1
  • 10
    • 0030762296 scopus 로고    scopus 로고
    • Calibration of Fura-2 signals introduces errors into measurement of thrombin-stimulated calcium mobilisation in human platelets
    • DOI 10.1016/S0009-8981(97)00139-3, PII S0009898197001393
    • C.J. Fowler, and G. Tiger Calibration of Fura-2 signals introduces errors into measurement of thrombin-stimulated calcium mobilisation in human platelets Clin. Chim. Acta 265 1997 247 261 (Pubitemid 27438283)
    • (1997) Clinica Chimica Acta , vol.265 , Issue.2 , pp. 247-261
    • Fowler, C.J.1    Tiger, G.2
  • 11
    • 68949148655 scopus 로고    scopus 로고
    • Capacity of oxidative phosphorylation in human skeletal muscle: New perspectives of mitochondrial physiology
    • E. Gnaiger Capacity of oxidative phosphorylation in human skeletal muscle: new perspectives of mitochondrial physiology Int. J. Biochem. Cell Biol. 41 2009 1837 1845
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 1837-1845
    • Gnaiger, E.1
  • 13
    • 46249123354 scopus 로고    scopus 로고
    • SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production
    • DOI 10.1083/jcb.200706171
    • K.N. Green, A. Demuro, Y. Akbari, B.D. Hitt, I.F. Smith, and I. Parker SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production J. Cell Biol. 181 2008 1107 1116 (Pubitemid 351915486)
    • (2008) Journal of Cell Biology , vol.181 , Issue.7 , pp. 1107-1116
    • Green, K.N.1    Demuro, A.2    Akbari, Y.3    Hitt, B.D.4    Smith, I.F.5    Parker, I.6    LaFerla, F.M.7
  • 14
    • 0033615580 scopus 로고    scopus 로고
    • The presenilins in Alzheimer's disease - Proteolysis holds the key
    • C. Haass, and B. De Strooper The presenilins in Alzheimer's disease - proteolysis holds the key Science 286 1999 916 919
    • (1999) Science , vol.286 , pp. 916-919
    • Haass, C.1    De Strooper, B.2
  • 15
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • J.A. Hardy, and G.A. Higgins Alzheimer's disease: the amyloid cascade hypothesis Science 256 1992 184 185
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 16
    • 3042781117 scopus 로고    scopus 로고
    • Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts
    • DOI 10.1042/BJ20040095
    • E. Hutter, K. Renner, G. Pfister, P. Stockl, P. Jansen-Durr, and E. Gnaiger Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts Biochem. J. 380 2004 919 928 (Pubitemid 38850535)
    • (2004) Biochemical Journal , vol.380 , Issue.3 , pp. 919-928
    • Hutter, E.1    Renner, K.2    Pfister, G.3    Stockl, P.4    Jansen-Durr, P.5    Gnaiger, E.6
  • 17
    • 29744454546 scopus 로고    scopus 로고
    • High-resolution respirometry-a modern tool in aging research
    • DOI 10.1016/j.exger.2005.09.011, PII S0531556505002305
    • E. Hutter, H. Unterluggauer, A. Garedew, P. Jansen-Durr, and E. Gnaiger High-resolution respirometry - a modern tool in aging research Exp. Gerontol. 41 2006 103 109 (Pubitemid 43031375)
    • (2006) Experimental Gerontology , vol.41 , Issue.1 , pp. 103-109
    • Hutter, E.1    Unterluggauer, H.2    Garedew, A.3    Jansen-Durr, P.4    Gnaiger, E.5
  • 18
    • 33745700370 scopus 로고    scopus 로고
    • Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40
    • S. Kumar-Singh, J. Theuns, B. Van Broeck, D. Pirici, K. Vennekens, and E. Corsmit Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40 Hum. Mutat. 27 2006 686 695
    • (2006) Hum. Mutat. , vol.27 , pp. 686-695
    • Kumar-Singh, S.1    Theuns, J.2    Van Broeck, B.3    Pirici, D.4    Vennekens, K.5    Corsmit, E.6
  • 19
    • 77957785420 scopus 로고    scopus 로고
    • Neurotoxicity of Alzheimer's disease Abeta peptides is induced by small changes in the Abeta(42) to Abeta(40) ratio
    • I. Kuperstein, K. Broersen, I. Benilova, J. Rozenski, W. Jonckheere, and M. Debulpaep Neurotoxicity of Alzheimer's disease Abeta peptides is induced by small changes in the Abeta(42) to Abeta(40) ratio EMBO J. 29 2010 3408 3420
    • (2010) EMBO J. , vol.29 , pp. 3408-3420
    • Kuperstein, I.1    Broersen, K.2    Benilova, I.3    Rozenski, J.4    Jonckheere, W.5    Debulpaep, M.6
  • 20
    • 32844465332 scopus 로고    scopus 로고
    • Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene
    • DOI 10.1007/s00415-005-0019-5
    • A.J. Larner, and M. Doran Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene J. Neurol. 253 2006 139 158 (Pubitemid 43255883)
    • (2006) Journal of Neurology , vol.253 , Issue.2 , pp. 139-158
    • Larner, A.J.1    Doran, M.2
  • 21
    • 67849085401 scopus 로고    scopus 로고
    • Genotype-phenotype relationships of presenilin-1 mutations in Alzheimer's disease: An update
    • A.J. Larner, and M. Doran Genotype-phenotype relationships of presenilin-1 mutations in Alzheimer's disease: an update J. Alzheimers Dis. 17 2009 259 265
    • (2009) J. Alzheimers Dis. , vol.17 , pp. 259-265
    • Larner, A.J.1    Doran, M.2
  • 23
    • 77952957701 scopus 로고    scopus 로고
    • The sarco/endoplasmic reticulum Ca(2 +) ATPase (SERCA) is the third element in capacitative calcium entry
    • I.M. Manjarres, A. Rodriguez-Garcia, M.T. Alonso, and J. Garcia-Sancho The sarco/endoplasmic reticulum Ca(2 +) ATPase (SERCA) is the third element in capacitative calcium entry Cell Calcium 47 2010 412 418
    • (2010) Cell Calcium , vol.47 , pp. 412-418
    • Manjarres, I.M.1    Rodriguez-Garcia, A.2    Alonso, M.T.3    Garcia-Sancho, J.4
  • 24
    • 0036987729 scopus 로고    scopus 로고
    • Contributions of mitochondrial alterations, resulting from bad genes and a hostile environment, to the pathogenesis of Alzheimer's disease
    • M.P. Mattson Contributions of mitochondrial alterations, resulting from bad genes and a hostile environment, to the pathogenesis of Alzheimer's disease Int. Rev. Neurobiol. 53 2002 387 409
    • (2002) Int. Rev. Neurobiol. , vol.53 , pp. 387-409
    • Mattson, M.P.1
  • 25
    • 57049143140 scopus 로고    scopus 로고
    • Mitochondria in neuroplasticity and neurological disorders
    • M.P. Mattson, M. Gleichmann, and A. Cheng Mitochondria in neuroplasticity and neurological disorders Neuron 60 2008 748 766
    • (2008) Neuron , vol.60 , pp. 748-766
    • Mattson, M.P.1    Gleichmann, M.2    Cheng, A.3
  • 26
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J. Immunol. Methods 65 1983 55 63 (Pubitemid 14203433)
    • (1983) Journal of Immunological Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 29
    • 0038045587 scopus 로고    scopus 로고
    • The production of amyloid β peptide is a critical requirement for the viability of central neurons
    • L.D. Plant, J.P. Boyle, I.F. Smith, C. Peers, and H.A. Pearson The production of amyloid beta peptide is a critical requirement for the viability of central neurons J. Neurosci. 23 2003 5531 5535 (Pubitemid 36807828)
    • (2003) Journal of Neuroscience , vol.23 , Issue.13 , pp. 5531-5535
    • Plant, L.D.1    Boyle, J.P.2    Smith, I.F.3    Peers, C.4    Pearson, H.A.5
  • 30
    • 68149148549 scopus 로고    scopus 로고
    • Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells
    • V. Rhein, G. Baysang, S. Rao, F. Meier, A. Bonert, and F. Muller-Spahn Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells Cell. Mol. Neurobiol. 29 2009 1063 1071
    • (2009) Cell. Mol. Neurobiol. , vol.29 , pp. 1063-1071
    • Rhein, V.1    Baysang, G.2    Rao, S.3    Meier, F.4    Bonert, A.5    Muller-Spahn, F.6
  • 32
    • 0037072511 scopus 로고    scopus 로고
    • 2+ entry in human neuroblastoma (SH-SY5Y) cells expressing a familial Alzheimer's disease presenilin-1 mutation
    • DOI 10.1016/S0006-8993(02)02970-0, PII S0006899302029700
    • I.F. Smith, J.P. Boyle, P.F. Vaughan, H.A. Pearson, R.F. Cowburn, and C.S. Peers Ca(2 +) stores and capacitative Ca(2 +) entry in human neuroblastoma (SH-SY5Y) cells expressing a familial Alzheimer's disease presenilin-1 mutation Brain Res. 949 2002 105 111 (Pubitemid 35246182)
    • (2002) Brain Research , vol.949 , Issue.1-2 , pp. 105-111
    • Smith, I.F.1    Boyle, J.P.2    Vaughan, P.F.T.3    Pearson, H.A.4    Cowburn, R.F.5    Peers, C.S.6
  • 35
    • 34548823253 scopus 로고    scopus 로고
    • The pathogenesis of Alzheimers disease - Is it a lifelong "calciumopathy"?
    • DOI 10.1177/1073858407299730
    • G.E. Stutzmann The pathogenesis of Alzheimers disease is it a lifelong "calciumopathy"? Neuroscientist 13 2007 546 559 (Pubitemid 47439831)
    • (2007) Neuroscientist , vol.13 , Issue.5 , pp. 546-559
    • Stutzmann, G.E.1
  • 37
    • 34247621471 scopus 로고    scopus 로고
    • Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models
    • DOI 10.1196/annals.1379.025, Imaging and the Aging Brain
    • G.E. Stutzmann, I. Smith, A. Caccamo, S. Oddo, I. Parker, and F. LaFerla Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models Ann. N. Y. Acad. Sci. 1097 2007 265 277 (Pubitemid 47084900)
    • (2007) Annals of the New York Academy of Sciences , vol.1097 , pp. 265-277
    • Stutzmann, G.E.1    Smith, I.2    Caccamo, A.3    Oddo, S.4    Parker, I.5    Laferla, F.6
  • 38
    • 3042806534 scopus 로고    scopus 로고
    • A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease
    • DOI 10.1016/j.mehy.2003.12.045, PII S0306987704001252
    • R.H. Swerdlow, and S.M. Khan A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease Med. Hypotheses 63 2004 8 20 (Pubitemid 38887104)
    • (2004) Medical Hypotheses , vol.63 , Issue.1 , pp. 8-20
    • Swerdlow, R.H.1    Khan, S.M.2
  • 39
    • 67649687124 scopus 로고    scopus 로고
    • The Alzheimer's disease mitochondrial cascade hypothesis: An update
    • R.H. Swerdlow, and S.M. Khan The Alzheimer's disease mitochondrial cascade hypothesis: an update Exp. Neurol. 218 2009 308 315
    • (2009) Exp. Neurol. , vol.218 , pp. 308-315
    • Swerdlow, R.H.1    Khan, S.M.2
  • 40
    • 0036982389 scopus 로고    scopus 로고
    • Mitochondria in Alzheimer's disease
    • R.H. Swerdlow, and S.J. Kish Mitochondria in Alzheimer's disease Int. Rev. Neurobiol. 53 2002 341 385
    • (2002) Int. Rev. Neurobiol. , vol.53 , pp. 341-385
    • Swerdlow, R.H.1    Kish, S.J.2
  • 42
    • 0033795824 scopus 로고    scopus 로고
    • In vivo control of respiration by cytochrome c oxidase in human cells
    • G. Villani, and G. Attardi In vivo control of respiration by cytochrome c oxidase in human cells Free Radic. Biol. Med. 29 2000 202 210
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 202-210
    • Villani, G.1    Attardi, G.2
  • 43
    • 0033610865 scopus 로고    scopus 로고
    • Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types
    • DOI 10.1074/jbc.273.48.31829
    • G. Villani, M. Greco, S. Papa, and G. Attardi Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types J. Biol. Chem. 273 1998 31829 31836 (Pubitemid 29177118)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.48 , pp. 31829-31836
    • Villani, G.1    Greco, M.2    Papa, S.3    Attardi, G.4
  • 44
    • 53749105377 scopus 로고    scopus 로고
    • Presenilins: Members of the gamma-secretase quartets, but part-time soloists too
    • T. Wakabayashi, and B. De Strooper Presenilins: members of the gamma-secretase quartets, but part-time soloists too Physiology 23 2008 194 204
    • (2008) Physiology , vol.23 , pp. 194-204
    • Wakabayashi, T.1    De Strooper, B.2
  • 45
    • 0033621152 scopus 로고    scopus 로고
    • Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease
    • DOI 10.1021/bi991080q
    • M.S. Wolfe, A.J. De Los, D.D. Miller, W. Xia, and D.J. Selkoe Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease Biochemistry 38 1999 11223 11230 (Pubitemid 29420941)
    • (1999) Biochemistry , vol.38 , Issue.35 , pp. 11223-11230
    • Wolfe, M.S.1    De Los Angeles, J.2    Miller, D.D.3    Xia, W.4    Selkoe, D.J.5
  • 46
    • 33646377385 scopus 로고    scopus 로고
    • Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels
    • G. Zatti, A. Burgo, M. Giacomello, L. Barbiero, R. Ghidoni, and G. Sinigaglia Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels Cell Calcium 39 2006 539 550
    • (2006) Cell Calcium , vol.39 , pp. 539-550
    • Zatti, G.1    Burgo, A.2    Giacomello, M.3    Barbiero, L.4    Ghidoni, R.5    Sinigaglia, G.6


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