Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene

Journal of Neurology

Volumn 253, Issue 2, 2006, Pages 139-158

  Larner, A J ^a   Doran, M ^a  

^a WALTON CENTRE FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Alzheimer's disease; Amyloid peptide; Frontotemporal dementia; Gamma secretase; Genotype phenotype correlation; Presenilin 1 gene

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; PRESENILIN 1;

AGE DISTRIBUTION; AGNOSIA; ALZHEIMER DISEASE; APHASIA; APRAXIA; ATAXIA; CHROMOSOME 14; CLINICAL FEATURE; DEMENTIA; DISEASE ASSOCIATION; DYSTONIA; EXTRAPYRAMIDAL SYMPTOM; GENE LOCATION; GENE MUTATION; GENETIC ANALYSIS; HUMAN; LEWY BODY; MYOCLONUS; NEUROIMAGING; NEUROPSYCHOLOGY; ONSET AGE; PARKINSONISM; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; SEIZURE;

AGE OF ONSET; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BEHAVIORAL SYMPTOMS; DEMENTIA; DNA MUTATIONAL ANALYSIS; GENETIC HETEROGENEITY; GENOTYPE; HUMANS; MEMBRANE PROTEINS; MUTATION; MYOCLONUS; NEURODEGENERATIVE DISEASES; PHENOTYPE; PRESENILIN-1; SEIZURES;

EID: 32844465332     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00415-005-0019-5     Document Type: Review

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