A neuroprotective role of the human uncoupling protein 2 (hUCP2) in a Drosophila Parkinson's Disease model

Neurobiology of Disease

Volumn 46, Issue 1, 2012, Pages 137-146

  Islam, Rafique ^a,c   Yang, Lichuan ^b   Sah, Megha ^a   Kannan, Kavitha ^a   Anamani, Denise ^a   Vijayan, Chibi ^a   Kwok, Jenny ^a   Cantino, Marie E ^a   Beal, M Flint ^b   Fridell, Yih Woei C ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

Dopaminergic (DA) neuron; Energy metabolism; Human uncoupling protein 2 (hUCP2); Mitochondrial oxidative phosphorylation; Parkinson's Disease (PD); Rotenone; Spargel

Indexed keywords

ADENOSINE TRIPHOSPHATE; DOPAMINE; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; TYROSINE 3 MONOOXYGENASE; UBIQUINOL CYTOCHROME C REDUCTASE; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOPAMINERGIC TRANSMISSION; DROSOPHILA; ENERGY BALANCE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; EPIDERMIS; FEMALE; GENE TARGETING; MALE; MITOCHONDRIAL GENE; MITOCHONDRIAL TRANSCRIPTION FACTOR A GENE; NERVE CELL NECROSIS; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PARKINSON DISEASE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STEADY STATE; UPREGULATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; DROSOPHILA MELANOGASTER; FEMALE; HUMANS; ION CHANNELS; MALE; MITOCHONDRIAL PROTEINS; PARKINSONIAN DISORDERS;

EID: 84862817879     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.12.055     Document Type: Article

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