메뉴 건너뛰기




Volumn 53, Issue 6, 2003, Pages 711-717

Mitochondrial uncoupling protein-2 protects the immature brain from excitotoxic neuronal death

Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 2;

EID: 0038443821     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.10543     Document Type: Article
Times cited : (222)

References (58)
  • 1
    • 0018862109 scopus 로고
    • Widespread patterns of neuronal damage following system or intracerebral injections of kainic acid: A histological study
    • Schwoh JE, Fuller T, Price TL, Olney JW. Widespread patterns of neuronal damage following system or intracerebral injections of kainic acid: a histological study. Neuroscience 1980;5:991-1014.
    • (1980) Neuroscience , vol.5 , pp. 991-1014
    • Schwoh, J.E.1    Fuller, T.2    Price, T.L.3    Olney, J.W.4
  • 2
    • 0019472821 scopus 로고
    • Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: Merabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy
    • Ben-Ari Y, Tremblay E, Riche D, et al. Electrographic, clinical and pathological alterations following systemic administration of kainic acid. bicuculline or pentetrazole: merabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy. Neuroscience 1981;6:1361-1391.
    • (1981) Neuroscience , vol.6 , pp. 1361-1391
    • Ben-Ari, Y.1    Tremblay, E.2    Riche, D.3
  • 3
    • 0032436145 scopus 로고    scopus 로고
    • Seizures in the developing brain: Perhaps not so benign after all
    • Holmes GL, Ben-Ari Y. Seizures in the developing brain: perhaps not so benign after all. Neuron 1998;21:1231-1234.
    • (1998) Neuron , vol.21 , pp. 1231-1234
    • Holmes, G.L.1    Ben-Ari, Y.2
  • 4
    • 0035943103 scopus 로고    scopus 로고
    • More evidence for seizure induced neuron loss: Is hippocampal sclerosis both cause and effect of epilepsy?
    • Sutula TP, Pitkanen A. More evidence for seizure induced neuron loss: is hippocampal sclerosis both cause and effect of epilepsy? Neurology 2001:57:169-170.
    • (2001) Neurology , vol.57 , pp. 169-170
    • Sutula, T.P.1    Pitkanen, A.2
  • 5
    • 0032212674 scopus 로고    scopus 로고
    • Neuropeptide-mediated excitability: A key triggering mechanism for seizure generation in the developing brain
    • Baram TZ, Hatalski CG. Neuropeptide-mediated excitability: a key triggering mechanism for seizure generation in the developing brain. Trends Neurosci 1998;21:471-476.
    • (1998) Trends Neurosci , vol.21 , pp. 471-476
    • Baram, T.Z.1    Hatalski, C.G.2
  • 6
    • 0032101776 scopus 로고    scopus 로고
    • Seizure induced neuronal injury: Vulnerability to febrile seizures in immature rat model
    • Toth Z, Yan XX, Hafroglou S, et al. Seizure induced neuronal injury: vulnerability to febrile seizures in immature rat model. J Neurosci 1998:18:4285-4294.
    • (1998) J Neurosci , vol.18 , pp. 4285-4294
    • Toth, Z.1    Yan, X.X.2    Hafroglou, S.3
  • 7
    • 0035689157 scopus 로고    scopus 로고
    • Resistance of immature hippocampus to morphologic and physiologic alterations following status epilepticus or kindling
    • Haas KZ, Sperher EF, Opanashuk LA, et al. Resistance of immature hippocampus to morphologic and physiologic alterations following status epilepticus or kindling. Hippocampus 2001;11:615-625.
    • (2001) Hippocampus , vol.11 , pp. 615-625
    • Haas, K.Z.1    Sperher, E.F.2    Opanashuk, L.A.3
  • 8
    • 0035197251 scopus 로고    scopus 로고
    • Brain development and generation of brain pathologies
    • Holmes GL, McCabe B. Brain development and generation of brain pathologies. Int Rev Neurobiol 2001;45:17-41.
    • (2001) Int Rev Neurobiol , vol.45 , pp. 17-41
    • Holmes, G.L.1    McCabe, B.2
  • 9
    • 0035873078 scopus 로고    scopus 로고
    • Status epilepticus causes necrotic damage in the mediodorsal nucleus of the thalamus in immature rats
    • Kubová H, Druga R, Lukasiuk K, et al. Status epilepticus causes necrotic damage in the mediodorsal nucleus of the thalamus in immature rats. J Neurosci 2001;21:3593-3599.
    • (2001) J Neurosci , vol.21 , pp. 3593-3599
    • Kubová, H.1    Druga, R.2    Lukasiuk, K.3
  • 10
    • 0025904583 scopus 로고
    • Autographic measurement of local cerebral beta-hydroxybutyrate uptake in the rat during postnatal development
    • Nehlig A, Boyet S, Pereira de Vasconcelos A. Autographic measurement of local cerebral beta-hydroxybutyrate uptake in the rat during postnatal development. Neuroscience 1991;40:871-878.
    • (1991) Neuroscience , vol.40 , pp. 871-878
    • Nehlig, A.1    Boyet, S.2    Pereira de Vasconcelos, A.3
  • 11
    • 0032982285 scopus 로고    scopus 로고
    • Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats
    • Fernandes MJ, Dubé C, Boyet S, et al. Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats. J Cereb Blood Flow Metab 1999;19:195-209.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 195-209
    • Fernandes, M.J.1    Dubé, C.2    Boyet, S.3
  • 12
    • 0030052530 scopus 로고    scopus 로고
    • Requirement for superoxide in excitotoxic cell death
    • Patel M, Day BJ, Crapo JD, et al. Requirement for superoxide in excitotoxic cell death. Neuron 1996;16:345.
    • (1996) Neuron , vol.16 , pp. 345
    • Patel, M.1    Day, B.J.2    Crapo, J.D.3
  • 13
    • 0034176843 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and neuronal glutamate excitotoxicity: Mortality and millivolts
    • Nicholls DG, Ward MW. Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts. Trends Neurosci 2000;23:166-174.
    • (2000) Trends Neurosci , vol.23 , pp. 166-174
    • Nicholls, D.G.1    Ward, M.W.2
  • 14
    • 18344380416 scopus 로고    scopus 로고
    • Mitochondrial dysfunction associated with neuronal death following status epilepticus in rat
    • Cock HR, Tong X, Hargreaves LP, et al. Mitochondrial dysfunction associated with neuronal death following status epilepticus in rat. Epilepsy Res 2002;48:157-168.
    • (2002) Epilepsy Res , vol.48 , pp. 157-168
    • Cock, H.R.1    Tong, X.2    Hargreaves, L.P.3
  • 15
    • 0032150860 scopus 로고    scopus 로고
    • Glutamate induced neuron death requires mitochondrial calcium uptake
    • Stout AK, Raphael HM, Kanterewicz BI, et al. Glutamate induced neuron death requires mitochondrial calcium uptake. Nat Neurosci 1998;1:366-373.
    • (1998) Nat Neurosci , vol.1 , pp. 366-373
    • Stout, A.K.1    Raphael, H.M.2    Kanterewicz, B.I.3
  • 16
    • 0036313059 scopus 로고    scopus 로고
    • Calcium induced cytochrome C release from CNS mitochondria is associated with the permeability transition and rapture of the outer membrane
    • Brustovetsky N, Brustovetsky T, Jemmerson R, Dubinsky JM. Calcium induced cytochrome C release from CNS mitochondria is associated with the permeability transition and rapture of the outer membrane. J Neurochem 2002;80:207-218.
    • (2002) J Neurochem , vol.80 , pp. 207-218
    • Brustovetsky, N.1    Brustovetsky, T.2    Jemmerson, R.3    Dubinsky, J.M.4
  • 17
    • 0029064518 scopus 로고
    • Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
    • Reynolds IJ, Hastings TG. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J Neurosci 1995;15:3318-3327.
    • (1995) J Neurosci , vol.15 , pp. 3318-3327
    • Reynolds, I.J.1    Hastings, T.G.2
  • 18
    • 0028900092 scopus 로고
    • Involvement of free radicals in excitotoxicity in vivo
    • Schulz JB, Henshaw DR, Siwak D, et al. Involvement of free radicals in excitotoxicity in vivo. J Neurochem 1995;64:2239-2247.
    • (1995) J Neurochem , vol.64 , pp. 2239-2247
    • Schulz, J.B.1    Henshaw, D.R.2    Siwak, D.3
  • 19
    • 0033578309 scopus 로고    scopus 로고
    • EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate induced neuropathology
    • Rong Y, Doctrow SR, Tocco G, Baudry M. EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate induced neuropathology. Proc Natl Acad Sci USA 1999;96:9897-9902.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 9897-9902
    • Rong, Y.1    Doctrow, S.R.2    Tocco, G.3    Baudry, M.4
  • 20
    • 0034237719 scopus 로고    scopus 로고
    • Energetics in the pathogenesis of neurodegenerative diseases
    • Beal MF. Energetics in the pathogenesis of neurodegenerative diseases. Trends Neurosci 2000;23:298-305.
    • (2000) Trends Neurosci , vol.23 , pp. 298-305
    • Beal, M.F.1
  • 22
    • 0033767740 scopus 로고    scopus 로고
    • Dietary supplement creatine protects against traumatic brain injury
    • Sullivan PG, Geiger JD, Mattson MP, Scheff S. Dietary supplement creatine protects against traumatic brain injury. Ann Neurol 2000;48:723-729.
    • (2000) Ann Neurol , vol.48 , pp. 723-729
    • Sullivan, P.G.1    Geiger, J.D.2    Mattson, M.P.3    Scheff, S.4
  • 23
    • 0029765443 scopus 로고    scopus 로고
    • Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its oneelectron reductants
    • Skulachev VP. Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its oneelectron reductants. Q Rev Biophys 1996;29:169-202.
    • (1996) Q Rev Biophys , vol.29 , pp. 169-202
    • Skulachev, V.P.1
  • 24
    • 0034740585 scopus 로고    scopus 로고
    • DeltaPsi(m)-dependent and -independent production of reactive oxygen species by rat brain mitochondria
    • Votyakova TV, Reynolds IJ. DeltaPsi(m)-dependent and -independent production of reactive oxygen species by rat brain mitochondria. J Neurochem 2001;79:266-277.
    • (2001) J Neurochem , vol.79 , pp. 266-277
    • Votyakova, T.V.1    Reynolds, I.J.2
  • 25
    • 0035214180 scopus 로고    scopus 로고
    • Uncoupling protein 2 in the brain: Distribution and function
    • Richard D, Clavel S, Huang Q, et al. Uncoupling protein 2 in the brain: distribution and function. Biochem Soc Trans 2001;29:812-817.
    • (2001) Biochem Soc Trans , vol.29 , pp. 812-817
    • Richard, D.1    Clavel, S.2    Huang, Q.3
  • 26
    • 0033492873 scopus 로고    scopus 로고
    • Brain uncoupling protein-2: Uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers
    • Horvath TL, Craig H, Warden CH, et al. Brain uncoupling protein-2: uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers. J Neurosci 1999;19:10417-10427.
    • (1999) J Neurosci , vol.19 , pp. 10417-10427
    • Horvath, T.L.1    Craig, H.2    Warden, C.H.3
  • 27
    • 0033667705 scopus 로고    scopus 로고
    • Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
    • Arsenijevic D, Onuma H, Pecqueur C, et al. Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet 2000;26:435-439.
    • (2000) Nat Genet , vol.26 , pp. 435-439
    • Arsenijevic, D.1    Onuma, H.2    Pecqueur, C.3
  • 28
    • 0034717015 scopus 로고    scopus 로고
    • Energy metabolism in uncoupling protein 3 gene knockout mice
    • Vidal-Puig AJ, Grujic D, Zhang CY, et al. Energy metabolism in uncoupling protein 3 gene knockout mice. J Biol Chem 2000;275:16258-16266.
    • (2000) J Biol Chem , vol.275 , pp. 16258-16266
    • Vidal-Puig, A.J.1    Grujic, D.2    Zhang, C.Y.3
  • 29
    • 18244379331 scopus 로고    scopus 로고
    • Superoxide activates mitochondrial uncoupling proteins
    • Echtay KS, Roussel D, St-Pierre J, et al. Superoxide activates mitochondrial uncoupling proteins. Nature 2002;415:96-99.
    • (2002) Nature , vol.415 , pp. 96-99
    • Echtay, K.S.1    Roussel, D.2    St-Pierre, J.3
  • 30
    • 0021688226 scopus 로고
    • Maturation of kainic acid seizure-brain damage syndrome in the rat. II. Histopathological sequelae
    • Nitecka L, Tremblay E, Charton G, et al. Maturation of kainic acid seizure-brain damage syndrome in the rat. II. Histopathological sequelae. Neuroscience 1984;13:1073-1094.
    • (1984) Neuroscience , vol.13 , pp. 1073-1094
    • Nitecka, L.1    Tremblay, E.2    Charton, G.3
  • 31
    • 0032504772 scopus 로고    scopus 로고
    • Distribution of uncoupling protein 2 mRNA in the mouse brain
    • Richard D, Rivest R, Huang Q, et al. Distribution of uncoupling protein 2 mRNA in the mouse brain. J Comp Neurol 1998;397:549-560.
    • (1998) J Comp Neurol , vol.397 , pp. 549-560
    • Richard, D.1    Rivest, R.2    Huang, Q.3
  • 32
    • 0034052613 scopus 로고    scopus 로고
    • Prolonged febrile seizures in the immature rat model enhance hippocampal excitability long-term
    • Dubé C, Chen K, Eghbal-Ahmadi M, et al. Prolonged febrile seizures in the immature rat model enhance hippocampal excitability long-term. Ann Neurol 2000;47:336-344.
    • (2000) Ann Neurol , vol.47 , pp. 336-344
    • Dubé, C.1    Chen, K.2    Eghbal-Ahmadi, M.3
  • 33
    • 0036616875 scopus 로고    scopus 로고
    • Developmental febrile seizures modulate hippocampal gene expression of hyperpolarization-activated channels in an isoform and cellspecific manner
    • Brewster A, Bender RA, Chen Y, et al. Developmental febrile seizures modulate hippocampal gene expression of hyperpolarization-activated channels in an isoform and cellspecific manner. J Neurosci 2002;22:4591-4599.
    • (2002) J Neurosci , vol.22 , pp. 4591-4599
    • Brewster, A.1    Bender, R.A.2    Chen, Y.3
  • 34
    • 0032213144 scopus 로고    scopus 로고
    • The in vivo proconvulsant effects of CRH in developing rat are independent of ionotropic glutamate receptor activation
    • Brunson K, Schultz L, Baram TZ. The in vivo proconvulsant effects of CRH in developing rat are independent of ionotropic glutamate receptor activation. Brain Res 1998;111:119-128.
    • (1998) Brain Res , vol.111 , pp. 119-128
    • Brunson, K.1    Schultz, L.2    Baram, T.Z.3
  • 36
    • 0032830065 scopus 로고    scopus 로고
    • Animal models of the ketogenic dier: What have we learned, what can we learn?
    • Stafstrom CE. Animal models of the ketogenic dier: what have we learned, what can we learn? Epilepsy Res 1999;37:241-259.
    • (1999) Epilepsy Res , vol.37 , pp. 241-259
    • Stafstrom, C.E.1
  • 37
    • 0035884944 scopus 로고    scopus 로고
    • Novel and transient populations of corricorropin-releasing hormone-expressing neurons in developing hippocampus suggest unique functional roles: A quantitative spatiotemporal analysis
    • Chen Y, Bender R, Frotscher M, et al. Novel and transient populations of corricorropin-releasing hormone-expressing neurons in developing hippocampus suggest unique functional roles: a quantitative spatiotemporal analysis. J Neurosci 2001;21:7171-7181.
    • (2001) J Neurosci , vol.21 , pp. 7171-7181
    • Chen, Y.1    Bender, R.2    Frotscher, M.3
  • 38
    • 0030887853 scopus 로고    scopus 로고
    • Genetic determinants of susceptibility to excitotoxic cell death: Implications for gene targeting approaches
    • Schauwecker PE, Steward O. Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches. Proc Natl Acad Sci USA 1997;94:4103-4108.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4103-4108
    • Schauwecker, P.E.1    Steward, O.2
  • 39
    • 0030901162 scopus 로고    scopus 로고
    • Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
    • Schmued LCY, Albertson C, Slikker W Jr. Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res 1997;751:37-46.
    • (1997) Brain Res , vol.751 , pp. 37-46
    • Schmued, L.C.Y.1    Albertson, C.2    Slikker W., Jr.3
  • 41
    • 0034669186 scopus 로고    scopus 로고
    • Mitochondrial superoxide production in kainate induced hippocampal damage
    • Liang LP, Ho YS, Patel, M. Mitochondrial superoxide production in kainate induced hippocampal damage. Neuroscience 2000;101:563-570.
    • (2000) Neuroscience , vol.101 , pp. 563-570
    • Liang, L.P.1    Ho, Y.S.2    Patel, M.3
  • 42
    • 0023191694 scopus 로고
    • Hippocampal neuron loss in temporal lobe epilepsy: Correlation with early childhood convulsions
    • Sagar HJ, Oxbury JM. Hippocampal neuron loss in temporal lobe epilepsy: correlation with early childhood convulsions. Ann Neurol 1987;22:334-340.
    • (1987) Ann Neurol , vol.22 , pp. 334-340
    • Sagar, H.J.1    Oxbury, J.M.2
  • 44
    • 0032620216 scopus 로고    scopus 로고
    • Basic mechanisms of status epilepticus
    • Coulter DA, DeLorenzo RJ. Basic mechanisms of status epilepticus. Adv Neurol 1999;79:725-733.
    • (1999) Adv Neurol , vol.79 , pp. 725-733
    • Coulter, D.A.1    DeLorenzo, R.J.2
  • 45
    • 0036456829 scopus 로고    scopus 로고
    • Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited
    • Mathern GW, Adelson PD, Cahan LD, Leite JP. Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited. Prog Brain Res 2002;135:237-251.
    • (2002) Prog Brain Res , vol.135 , pp. 237-251
    • Mathern, G.W.1    Adelson, P.D.2    Cahan, L.D.3    Leite, J.P.4
  • 46
    • 0036458341 scopus 로고    scopus 로고
    • Repeated brief seizures induce progressive hippocampal neuron loss and memory deficits
    • Kodoski R, Lynch M, Lauersdorf S, Sutula T. Repeated brief seizures induce progressive hippocampal neuron loss and memory deficits. Prog Brain Res 2002;135:95-110.
    • (2002) Prog Brain Res , vol.135 , pp. 95-110
    • Kodoski, R.1    Lynch, M.2    Lauersdorf, S.3    Sutula, T.4
  • 47
    • 0040449520 scopus 로고    scopus 로고
    • Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy
    • Kalviainen R, Salmenpera T, Partanen K, et al. Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy. Neurology 1998;50:1377-1382.
    • (1998) Neurology , vol.50 , pp. 1377-1382
    • Kalviainen, R.1    Salmenpera, T.2    Partanen, K.3
  • 48
    • 0036456444 scopus 로고    scopus 로고
    • Progression of neuronal damage after status epilepticus and during spontaneous seizures in a rat model of temporal lobe epilepsy
    • Pitkanen A, Nissinen J, Nairismagi J, et al. Progression of neuronal damage after status epilepticus and during spontaneous seizures in a rat model of temporal lobe epilepsy. Prog Brain Res 2002;135:67-83.
    • (2002) Prog Brain Res , vol.135 , pp. 67-83
    • Pitkanen, A.1    Nissinen, J.2    Nairismagi, J.3
  • 49
    • 0032913950 scopus 로고    scopus 로고
    • Progression in mesial temporal lobe epilepsy
    • Sutula TP, Hermann B. Progression in mesial temporal lobe epilepsy. Ann Neurol 1999;45:553-556.
    • (1999) Ann Neurol , vol.45 , pp. 553-556
    • Sutula, T.P.1    Hermann, B.2
  • 50
    • 0037161367 scopus 로고    scopus 로고
    • Cognitive outcomes and predictive factors in epilepsy
    • Meador KJ. Cognitive outcomes and predictive factors in epilepsy. Neurology 2002;58(suppl 5):S21-S26.
    • (2002) Neurology , vol.58 , Issue.SUPPL. 5
    • Meador, K.J.1
  • 51
    • 0036454727 scopus 로고    scopus 로고
    • Is neuronal death required for seizure induced epileptogenesis in the immature brain?
    • Baram TZ, Eghbal-Ahmadi M, Bender RA. Is neuronal death required for seizure induced epileptogenesis in the immature brain? Prog Brain Res 2002;135:365-375.
    • (2002) Prog Brain Res , vol.135 , pp. 365-375
    • Baram, T.Z.1    Eghbal-Ahmadi, M.2    Bender, R.A.3
  • 52
    • 0028127308 scopus 로고
    • Quinolinate induced injury is enhanced in developing rat brain
    • Trescher WH, McDonald JW, Johnston MV. Quinolinate induced injury is enhanced in developing rat brain. Dev Brain Res 1994;83:224-232.
    • (1994) Dev Brain Res , vol.83 , pp. 224-232
    • Trescher, W.H.1    McDonald, J.W.2    Johnston, M.V.3
  • 53
    • 0022566936 scopus 로고
    • Excitotoxic mechanisms of epileptic brain damage
    • Olney JW, Collins RC, Sloviter RS. Excitotoxic mechanisms of epileptic brain damage. Adv Neurol 1986;44:857-877.
    • (1986) Adv Neurol , vol.44 , pp. 857-877
    • Olney, J.W.1    Collins, R.C.2    Sloviter, R.S.3
  • 54
    • 0032531738 scopus 로고    scopus 로고
    • Patterns of status epilepticus induced neuronal injury during development and long-term consequences
    • Sankar R, Shin DH, Liu H, et al. Patterns of status epilepticus induced neuronal injury during development and long-term consequences. J Neurosci 1998;18:8382-8393.
    • (1998) J Neurosci , vol.18 , pp. 8382-8393
    • Sankar, R.1    Shin, D.H.2    Liu, H.3
  • 55
    • 0036683694 scopus 로고    scopus 로고
    • Brain mitochondrial uncoupling protein 2 (UCP2) a protective stress signal in neuronal injury
    • Bechmann I, Diano S, Warden CH, et al. Brain mitochondrial uncoupling protein 2 (UCP2) a protective stress signal in neuronal injury. Biochem Pharmacol 2002;64:363-367.
    • (2002) Biochem Pharmacol , vol.64 , pp. 363-367
    • Bechmann, I.1    Diano, S.2    Warden, C.H.3
  • 56
    • 0036214365 scopus 로고    scopus 로고
    • Induction of uncoupling protein 2 mRNA in β-cells is stimulated by oxidation of fatty acids but not by nutrient oversupply
    • Li LX, Skorpen F, Egeberg K, et al. Induction of uncoupling protein 2 mRNA in β-cells is stimulated by oxidation of fatty acids but not by nutrient oversupply. Endocrinology 2002;143:1371-1377.
    • (2002) Endocrinology , vol.143 , pp. 1371-1377
    • Li, L.X.1    Skorpen, F.2    Egeberg, K.3
  • 57
    • 0027979943 scopus 로고
    • The prevalence and incidence of convulsive disorders in children
    • Hauser WA. The prevalence and incidence of convulsive disorders in children. Epilepsia 1994;35(suppl 2):S1-S6.
    • (1994) Epilepsia , vol.35 , Issue.SUPPL. 2
    • Hauser, W.A.1
  • 58
    • 0028826484 scopus 로고
    • Unprovoked seizures and development disabilities: Clinical characteristics of children referred to a child development center
    • Nevo Y, Shinnar S, Samuel E, et al. Unprovoked seizures and development disabilities: clinical characteristics of children referred to a child development center. Pediatric Neurol 1995;13:235-241.
    • (1995) Pediatric Neurol , vol.13 , pp. 235-241
    • Nevo, Y.1    Shinnar, S.2    Samuel, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.