Effect of MPTP on brain mitochondrial H2O2 and ATP production and on dopamine and DOPAC in the striatum

Journal of Physiology and Biochemistry

Volumn 55, Issue 4, 1999, Pages 325-332

  Fahre, E ^b   Monserrat, J ^b   Herrero, A ^b   Barja, G ^a   Leret, M L ^b  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b NONE

Author keywords

ATP production; Brain; Free radical; H2O2 production; MPP+; MPTP

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3,4 DIHYDROXYPHENYLACETIC ACID; ADENOSINE TRIPHOSPHATE; DOPAMINE; FREE RADICAL; HYDROGEN PEROXIDE; MANDELIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CONTROLLED STUDY; CORPUS STRIATUM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOPAMINERGIC SYSTEM; MALE; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; RAT;

1-METHYL-4-PHENYLPYRIDINIUM; 3,4-DIHYDROXYPHENYLACETIC ACID; ADENOSINE TRIPHOSPHATE; ANIMALS; BRAIN; CORPUS STRIATUM; DOPAMINE; HYDROGEN PEROXIDE; MALE; MPTP POISONING; OXIDATIVE STRESS; RATS; RATS, WISTAR;

EID: 0033492181     PISSN: 11387548     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Barja, G. and Herrero, A. (1998): J. Bioenerg.Biomembr., 30, 235-243.
2. Barja, G. (1999): In "Methods in Aging Research" (Yu, B. P. ed.), CRC Press, Boca Raton, USA. pp. 533-548.
3. Blandini, F., Nappi, G. and Greenamyre, J. T. (1998): Movem. Disord., 13, 11-15.
4. Cassarino D. S., Fall, C.P., Swerdlow, R. H., Smith, T. S., Halvorsen, E. M., Miller, S. W., Parks, J. P., Parker Jr, W. D. and Bennett Jr., J. P. (1997): Biochim. Biophys. Acta, 1362, 77-86.
5. Cassarino, D. S., Fall, C.P., Smith, T. S. and Bennett Jr., J. P. (1998): J. Neurochem., 71, 295-301.
6. Chan, P., DeLanney, L. E., Irwin, I., Langston, J. W. and Di Monte, D. (1991): J. Neurochem, 57, 348-351.
7. Chiueh, C. C., Kishna, G., Tulsi, P., Obata, T., Lang, K., Huang, S. J. and Murphy, D. L. (1992): Free Rad. Biol. Med., 13, 581-583.
8. Cleeter, M. W. J., Cooper, J. M. and Schapira, A. H. V. (1992): J. Neurochem., 58, 786-789.
9. Cohen, G. (1990): J. Neural Transm., 32S, 229.
10. Harik, S. I., Schmidley, J. W., Iacofano, L. A., Blue, P., Arora, P. K. and Sayre, L. M. (1987): J. Pharmacol. Exper. Therap., 241, 669-676.
11. Hasegawa, E. K., Takeshigue, K., Oishi, T., Murai, Y. and Minakami, S. (1990): Biochem. Biophys. Res. Comms., 170, 1049-1055.
12. Hasegawa, E., Kang, D., Sakamoto, K., Mitsumoto, A., Nagano, T., Minakami, S. and Takeshigue K. (1997): Arch. Biochem. Biophys., 337, 69-74.
13. Jenner, P. (1998): Movem. Disord., 13, 24-34.
14. Johannessen, J. N., Chiueh, C. C., Burns, R. S. and Markey, S. P. (1985): Life Sci., 36, 219-224.
15. Khan, U., Filiano, B., King, M. P. and Przedborski, S. (1997): Neurol., 48, A201.
16. Klivenyi, P., Matthews, R. T., Wermer, M., Yang, L., MacGarvey, U., Becker, D. A., Natero, R. and Beal, M. F. (1998): Exper. Neurol., 152, 163-166.
17. Lai, J. C. K. and Clark, J. B. (1979): Methods Enzymol., 55, 51-60.
18. Nicklas, W.J., Vyas, I. and Heikkila, R.E. (1985): Life Sci., 36, 2503-2508.
19. Paxinos, G. and Watson, C. (1992): "The rat brain in stereotaxic coordinates". Academic Press, San Diego.
20. Przedborski, S., Kostic, V., Jackson-Lewis, V., Naini, A. B., Simonetti, S., Fahn, S., Carlson, E., Epstein, C. J., and Cadet, J. L. (1992): J. Neurosci., 12, 1658-1667.
21. Przedborsky, S. and Jackson-Lewis, V. (1998): Movem. Disord., 13, 35-38.
22. Riachi, N. J., LaManna, J. C. and Harick, S. I. (1989): J. Pharmacol. Exper. Therapeut., 249, 744-748.
23. Riachi, N. J., Dietrich, W. D. and Harik, S. I. (1990): Brain Res., 533, 6-14.
24. Scotcher, K. P., Irwin, I., DeLanney, L. E., Langston, J. W. and Di Monte, D. (1990): J. Neurochem., 54, 1295-1301.
25. Sriram, K., Pai, K. S., Boyd, M. R. and Ravindranath, V. (1997): Brain Res., 749, 44-52.
26. Tatton, N. A. and Kish, S. J. (1997): Neurosci., 77, 1037-1048.
27. Turrens, J. F. and Boveris, A. (1980): Biochem. J., 191, 421-427.
28. Zeevalk, G. D., Bernard, L. P. and Nicklas, W. J. (1998): J. Neurochem., 70, 1421-1430.