-
1
-
-
0034671596
-
Extended life-span conferred by cotransporter gene mutations in Drosophila
-
Rogina B, Reenan RA, Nilsen SP, Helfand SL (2000) Extended life-span conferred by cotransporter gene mutations in Drosophila. Science 290:2137-2140.
-
(2000)
Science
, vol.290
, pp. 2137-2140
-
-
Rogina, B.1
Reenan, R.A.2
Nilsen, S.P.3
Helfand, S.L.4
-
2
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
Murphy CT, et al. (2003) Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424:277-283.
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
-
3
-
-
33749999763
-
Group testing for pathway analysis improves comparability of different microarray datasets
-
Manoli T, et al. (2006) Group testing for pathway analysis improves comparability of different microarray datasets. Bioinformatics 22:2500-2506.
-
(2006)
Bioinformatics
, vol.22
, pp. 2500-2506
-
-
Manoli, T.1
-
4
-
-
0033982936
-
KEGG: Kyoto encyclopedia of genes and genomes
-
Kanehisa M, Goto S (2000) KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28:27-30.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 27-30
-
-
Kanehisa, M.1
Goto, S.2
-
5
-
-
0034069495
-
Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner M, et al. (2000) Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25:25-29.
-
(2000)
Nat Genet
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
-
6
-
-
0037458617
-
Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span
-
Fei YJ, Inoue K, Ganapathy V (2003) Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span. J Biol Chem 278:6136-6144.
-
(2003)
J Biol Chem
, vol.278
, pp. 6136-6144
-
-
Fei, Y.J.1
Inoue, K.2
Ganapathy, V.3
-
7
-
-
1842844288
-
Relevance of NAC-2, an Na-+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans
-
Fei YJ, et al. (2004) Relevance of NAC-2, an Na-+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans. Biochem J 379:191-198.
-
(2004)
Biochem J
, vol.379
, pp. 191-198
-
-
Fei, Y.J.1
-
8
-
-
20144366852
-
Rapid iterative negative geotaxis (RING): A new method for assessing age-related locomotor decline in Drosophila
-
Gargano JW, Martin I, Bhandari P, Grotewiel MS (2005) Rapid iterative negative geotaxis (RING): A new method for assessing age-related locomotor decline in Drosophila. Exp Gerontol 40:386-395.
-
(2005)
Exp Gerontol
, vol.40
, pp. 386-395
-
-
Gargano, J.W.1
Martin, I.2
Bhandari, P.3
Grotewiel, M.S.4
-
9
-
-
0037452882
-
Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies
-
Marden JH, Rogina B, Montooth KL, Helfand SL (2003) Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies. Proc Natl Acad Sci USA 100:3369-3373.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3369-3373
-
-
Marden, J.H.1
Rogina, B.2
Montooth, K.L.3
Helfand, S.L.4
-
10
-
-
33749668581
-
Distinct genetic influences on locomotor senescence in Drosophila revealed by a series of metrical analyses
-
Martin I, Grotewiel MS (2006) Distinct genetic influences on locomotor senescence in Drosophila revealed by a series of metrical analyses. Exp Gerontol 41:877-881.
-
(2006)
Exp Gerontol
, vol.41
, pp. 877-881
-
-
Martin, I.1
Grotewiel, M.S.2
-
11
-
-
0037195166
-
Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy
-
Knauf F, Rogina B, Jiang Z, Aronson PS, Helfand SL (2002) Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy. Proc Natl Acad Sci USA 99:14315-14319.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14315-14319
-
-
Knauf, F.1
Rogina, B.2
Jiang, Z.3
Aronson, P.S.4
Helfand, S.L.5
-
12
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal RS, Weindruch R (1996) Oxidative stress, caloric restriction, and aging. Science 273:59-63.
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
13
-
-
0038010034
-
Tissue-specific gene expression and ecdysone-regulated genomic networks in Drosophila
-
Li TR, White KP (2003) Tissue-specific gene expression and ecdysone-regulated genomic networks in Drosophila. Dev Cell 5:59-72.
-
(2003)
Dev Cell
, vol.5
, pp. 59-72
-
-
Li, T.R.1
White, K.P.2
-
14
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, et al. (2005) Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102:15545-15550.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
15
-
-
0042424602
-
Statistical significance for genomewide studies
-
Storey JD, Tibshirani R (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci USA 100:9440-9445.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
16
-
-
37249049422
-
AGEMAP: A gene expression database for aging in mice
-
Zahn JM, et al. (2007) AGEMAP: A gene expression database for aging in mice. PLoS Genet 3:e201.
-
(2007)
PLoS Genet
, vol.3
-
-
Zahn, J.M.1
-
17
-
-
0842267618
-
Comparing genomic expression patterns across species identifies shared transcriptional profile in aging
-
McCarroll SA, et al. (2004) Comparing genomic expression patterns across species identifies shared transcriptional profile in aging. Nat Genet 36:197-204.
-
(2004)
Nat Genet
, vol.36
, pp. 197-204
-
-
McCarroll, S.A.1
-
18
-
-
0030729851
-
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
-
Korshunov SS, Skulachev VP, Starkov AA (1997) High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett 416:15-18.
-
(1997)
FEBS Lett
, vol.416
, pp. 15-18
-
-
Korshunov, S.S.1
Skulachev, V.P.2
Starkov, A.A.3
-
19
-
-
23944494249
-
Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly
-
Fridell YW, Sanchez-Blanco A, Silvia BA, Helfand SL (2005) Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly. Cell Metab 1:145-152.
-
(2005)
Cell Metab
, vol.1
, pp. 145-152
-
-
Fridell, Y.W.1
Sanchez-Blanco, A.2
Silvia, B.A.3
Helfand, S.L.4
-
20
-
-
32444437067
-
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
-
Lopez-Lluch G, et al. (2006) Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. Proc Natl Acad Sci USA 103:1768-1773.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1768-1773
-
-
Lopez-Lluch, G.1
-
21
-
-
17844385363
-
Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo
-
Bogacka I, Xie H, Bray GA, Smith SR (2005) Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo. Diabetes 54:1392-1399.
-
(2005)
Diabetes
, vol.54
, pp. 1392-1399
-
-
Bogacka, I.1
Xie, H.2
Bray, G.A.3
Smith, S.R.4
-
22
-
-
33947710793
-
Calorie restriction increases muscle mitochondrial biogenesis in healthy humans
-
Civitarese AE, et al. (2007) Calorie restriction increases muscle mitochondrial biogenesis in healthy humans. PLoS Med 4:e76.
-
(2007)
PLoS Med
, vol.4
-
-
Civitarese, A.E.1
-
23
-
-
33847344733
-
Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle
-
Ukropcova B, et al. (2007) Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle. Diabetes 56:720-727.
-
(2007)
Diabetes
, vol.56
, pp. 720-727
-
-
Ukropcova, B.1
-
24
-
-
0037326196
-
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): Transcriptional coactivator and metabolic regulator
-
Puigserver P, Spiegelman BM (2003) Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): Transcriptional coactivator and metabolic regulator. Endocr Rev 24:78-90.
-
(2003)
Endocr Rev
, vol.24
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
25
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z, et al. (1999) Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98:115-124.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
-
26
-
-
34248207609
-
High-resolution dynamics of the transcriptional response to nutrition in Drosophila: A key role for dFOXO
-
Gershman B, et al. (2007) High-resolution dynamics of the transcriptional response to nutrition in Drosophila: A key role for dFOXO. Physiol Genomics 29:24-34.
-
(2007)
Physiol Genomics
, vol.29
, pp. 24-34
-
-
Gershman, B.1
-
27
-
-
34447105745
-
Aging impact on biochemical activities and gene expression of Drosophila melanogaster mitochondria
-
Dubessay P, et al. (2007) Aging impact on biochemical activities and gene expression of Drosophila melanogaster mitochondria. Biochimie 89:988-1001.
-
(2007)
Biochimie
, vol.89
, pp. 988-1001
-
-
Dubessay, P.1
-
28
-
-
25144463436
-
Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster
-
Ferguson M, Mockett RJ, Shen Y, Orr WC, Sohal RS (2005) Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster. Biochem J 390:501-511.
-
(2005)
Biochem J
, vol.390
, pp. 501-511
-
-
Ferguson, M.1
Mockett, R.J.2
Shen, Y.3
Orr, W.C.4
Sohal, R.S.5
-
29
-
-
27844564005
-
Behavioral, physical, and demographic changes in Drosophila populations through dietary restriction
-
Bross TG, Rogina B, Helfand SL (2005) Behavioral, physical, and demographic changes in Drosophila populations through dietary restriction. Aging Cell 4:309-317.
-
(2005)
Aging Cell
, vol.4
, pp. 309-317
-
-
Bross, T.G.1
Rogina, B.2
Helfand, S.L.3
-
30
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
32
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Smyth GK (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3:1-29.
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
, pp. 1-29
-
-
Smyth, G.K.1
-
33
-
-
35748949257
-
A comparison of background correction methods for twocolour microarrays
-
Ritchie ME, et al. (2007) A comparison of background correction methods for twocolour microarrays. Bioinformatics 23:2700-2707.
-
(2007)
Bioinformatics
, vol.23
, pp. 2700-2707
-
-
Ritchie, M.E.1
-
34
-
-
0242333835
-
Normalization of cDNA microarray data
-
Smyth GK, Speed T (2003) Normalization of cDNA microarray data. Methods 31:265-273.
-
(2003)
Methods
, vol.31
, pp. 265-273
-
-
Smyth, G.K.1
Speed, T.2
|