-
1
-
-
11144243412
-
Modulation of neurodegeneration by molecular chaperones
-
Muchowski PJ, Wacker JL. Modulation of neurodegeneration by molecular chaperones. Nat Rev Neurosci 2005, 6: 11-22.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 11-22
-
-
Muchowski, P.J.1
Wacker, J.L.2
-
2
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997, 276: 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
-
3
-
-
0242300619
-
alpha-Synuclein locus triplications cause Parkinson's disease
-
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, et al. alpha-Synuclein locus triplications cause Parkinson's disease. Science 2003, 302: 841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
-
4
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
-
Parker WD Jr, Boyson SJ, Parks JK. Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann Neurol 1989, 26: 719-723.
-
(1989)
Ann Neurol
, vol.26
, pp. 719-723
-
-
Parker Jr, W.D.1
Boyson, S.J.2
Parks, J.K.3
-
5
-
-
0035214256
-
Neurochemical findings in the MPTP model of Parkinson's disease
-
Schmidt N, Ferger BJ. Neurochemical findings in the MPTP model of Parkinson's disease. J Neural Transm 2001, 108: 1263-1282.
-
(2001)
J Neural Transm
, vol.108
, pp. 1263-1282
-
-
Schmidt, N.1
Ferger, B.J.2
-
6
-
-
0037104723
-
An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
-
Sherer TB, Betarbet R, Stout AK, Lund S, Baptista M, Panov AV, et al. An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. J Neurosci 2002, 22: 7006-7015.
-
(2002)
J Neurosci
, vol.22
, pp. 7006-7015
-
-
Sherer, T.B.1
Betarbet, R.2
Stout, A.K.3
Lund, S.4
Baptista, M.5
Panov, A.V.6
-
7
-
-
0018187738
-
A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes
-
Ciehanover A, Hod Y, Hershko A. A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes. Biochem Biophy Res Commun 1978, 81: 1100-1105.
-
(1978)
Biochem Biophy Res Commun
, vol.81
, pp. 1100-1105
-
-
Ciehanover, A.1
Hod, Y.2
Hershko, A.3
-
8
-
-
0035900793
-
CHIP is a U-box-dependent E3 ubiquitin ligase: Identification of Hsc70 as a target for ubquitylation
-
Jiang J, Ballinger CA, Wu Y, Dai Q, Cyr DM, Hohfeld J, et al. CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubquitylation. J Biol Chem 2001, 276: 42938-42944.
-
(2001)
J Biol Chem
, vol.276
, pp. 42938-42944
-
-
Jiang, J.1
Ballinger, C.A.2
Wu, Y.3
Dai, Q.4
Cyr, D.M.5
Hohfeld, J.6
-
9
-
-
0041430614
-
Dysfunction of mitochondrial complex I and the proteasome: Interactions between two biochemical deficits in a cellular model of Parkinson's disease
-
Hoglinger GU, Carrard G, Michel PP, Medja F, Hirsch EC. Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease. J Neurochem 2003, 86: 1297-1307.
-
(2003)
J Neurochem
, vol.86
, pp. 1297-1307
-
-
Hoglinger, G.U.1
Carrard, G.2
Michel, P.P.3
Medja, F.4
Hirsch, E.C.5
-
10
-
-
0032969563
-
+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes
-
+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res 1999, 9: 27-43.
-
(1999)
Genome Res
, vol.9
, pp. 27-43
-
-
Neuwald, A.F.1
Aravind, L.2
Spouge, J.L.3
Koonin, E.V.4
-
11
-
-
10944257609
-
Neurodegenerative conditions associated with ageing: A molecular interplay
-
Troulinaki K, Tavernarakis N. Neurodegenerative conditions associated with ageing: a molecular interplay. Mech Ageing Dev 2005, 126: 23-33.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 23-33
-
-
Troulinaki, K.1
Tavernarakis, N.2
-
12
-
-
0036846119
-
TorsinA and heat shock proteins act as molecular chaperones: Suppression of alpha-synuclein aggregation
-
Mclean PJ, Kawamata H, Shariff S, Hewett J, Sharma N, Ueda K, et al. TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation. J Neuronchem 2002, 83: 846-854.
-
(2002)
J Neuronchem
, vol.83
, pp. 846-854
-
-
Mclean, P.J.1
Kawamata, H.2
Shariff, S.3
Hewett, J.4
Sharma, N.5
Ueda, K.6
-
13
-
-
0037319121
-
Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins
-
Caldwell GA, Cao S, Sexton EG, Gelwix CC, Bevel JP, Caldwell KA. Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins. Hum Mol Genet 2003, 12: 307-319.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 307-319
-
-
Caldwell, G.A.1
Cao, S.2
Sexton, E.G.3
Gelwix, C.C.4
Bevel, J.P.5
Caldwell, K.A.6
-
14
-
-
0028064964
-
Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: Evidence for a primary involvement of energy depletion
-
Bates TE, Heales SJ, Davies SE, Boakye P, Clark JB. Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. J Neurochem 1994, 63: 640-648.
-
(1994)
J Neurochem
, vol.63
, pp. 640-648
-
-
Bates, T.E.1
Heales, S.J.2
Davies, S.E.3
Boakye, P.4
Clark, J.B.5
-
15
-
-
0037085288
-
Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors
-
Lee HJ, Shin SY, Choi C, Lee YH, Lee SJ. Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors. J Biol Chem 2001, 277: 5411-5417.
-
(2001)
J Biol Chem
, vol.277
, pp. 5411-5417
-
-
Lee, H.J.1
Shin, S.Y.2
Choi, C.3
Lee, Y.H.4
Lee, S.J.5
-
16
-
-
0033966487
-
Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP
-
Vila M, Vukosavic S, Jackson-Lewis V, Neystat M, Jakowec M, Przedborski S. Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP. J Neurochem 2000, 74: 721-729.
-
(2000)
J Neurochem
, vol.74
, pp. 721-729
-
-
Vila, M.1
Vukosavic, S.2
Jackson-Lewis, V.3
Neystat, M.4
Jakowec, M.5
Przedborski, S.6
-
18
-
-
0036278335
-
Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson disease
-
Xu J, Kao SY, Lee FJ, Song W, Jin LW, Yankner BA. Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease. Nat Med 2002, 8: 600-606
-
(2002)
Nat Med
, vol.8
, pp. 600-606
-
-
Xu, J.1
Kao, S.Y.2
Lee, F.J.3
Song, W.4
Jin, L.W.5
Yankner, B.A.6
-
19
-
-
0034326816
-
Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity
-
Tabrizi SJ, Orth M, Wilkinson JM, Taanman JW, Warner TT, Cooper JM, et al. Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity. Hum Mol Genet 2000, 9: 2683-2689.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2683-2689
-
-
Tabrizi, S.J.1
Orth, M.2
Wilkinson, J.M.3
Taanman, J.W.4
Warner, T.T.5
Cooper, J.M.6
-
20
-
-
0034663039
-
The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity
-
Ostrerova-Golts N, Petrucelli L, Hardy J, Lee JM, Farer M, Wolozin B. The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity. J Neurosci 2000, 20: 6048-6054.
-
(2000)
J Neurosci
, vol.20
, pp. 6048-6054
-
-
Ostrerova-Golts, N.1
Petrucelli, L.2
Hardy, J.3
Lee, J.M.4
Farer, M.5
Wolozin, B.6
-
21
-
-
0037971209
-
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein
-
Lakso M, Vartiainen S, Moilanen AM, Sirviö J, Thomas JH, Nass R, et al. Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein. J Neurochem 2003, 86: 165-172.
-
(2003)
J Neurochem
, vol.86
, pp. 165-172
-
-
Lakso, M.1
Vartiainen, S.2
Moilanen, A.M.3
Sirviö, J.4
Thomas, J.H.5
Nass, R.6
-
22
-
-
33748792821
-
Opposing activities protect against age-onset proteotoxicity
-
Cohen E, Bieschke J, Perciavalle RM, Kelly JW, Dillin A. Opposing activities protect against age-onset proteotoxicity. Science 2006, 313: 1604-1610.
-
(2006)
Science
, vol.313
, pp. 1604-1610
-
-
Cohen, E.1
Bieschke, J.2
Perciavalle, R.M.3
Kelly, J.W.4
Dillin, A.5
-
23
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974, 77: 71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
24
-
-
0037022668
-
Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans
-
Nass R, Hall DH, Miller DM, Blakely RD. Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans. Proc Natl Acad Sci USA 2002, 99: 3264-3269.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3264-3269
-
-
Nass, R.1
Hall, D.H.2
Miller, D.M.3
Blakely, R.D.4
-
25
-
-
34347221219
-
Caenorhabditis elegans as a model system for Parkinson's disease
-
Schmidt E, Seifert M, Baumeister R. Caenorhabditis elegans as a model system for Parkinson's disease. Neurodegener Dis 2007, 4: 199-217
-
(2007)
Neurodegener Dis
, vol.4
, pp. 199-217
-
-
Schmidt, E.1
Seifert, M.2
Baumeister, R.3
-
26
-
-
29344467120
-
A developmental timing microRNA and its Target regulate life span in C. elegans
-
Michelle Boehm, Frank Slack. A developmental timing microRNA and its Target regulate life span in C. elegans. Science 2005, 310: 1954-1957.
-
(2005)
Science
, vol.310
, pp. 1954-1957
-
-
Boehm, M.1
Slack, F.2
-
27
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
Arrasate M, Mitra SM, Schweitzer ES, Segal MR, Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 2004, 431: 805-810.
-
(2004)
Nature
, vol.431
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.M.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
28
-
-
17544369017
-
Parkinson's disease
-
Clarke C, Moore AP. Parkinson's disease. Clin Evid 2004, 11: 1736-1754.
-
(2004)
Clin Evid
, vol.11
, pp. 1736-1754
-
-
Clarke, C.1
Moore, A.P.2
|