1,3,4-oxadiazole: A biologically active scaffold

Mini-Reviews in Medicinal Chemistry

Volumn 12, Issue 8, 2012, Pages 789-801

  Khalilullah, H ^a,b   Ahsan, M J ^b,c   Hedaitullah, Md ^d   Khan, S ^e   Ahmed, B ^a  

^a HAMDARD UNIVERSITY   (India)

^b Alwar Pharmacy College   (India)

^c NIMS UNIVERSITY   (India)

^d HIMT College of Pharmacy   (India)

^e QASSIM UNIVERSITY   (Saudi Arabia)

Author keywords

1,3,4 oxadiazole; Azole; Oxadiazole

Indexed keywords

1,3,4 OXADIAZOLE DERIVATIVE; 2 KETO 1,3,4 OXADIAZOLE DERIVATIVE; 3 [(5 CHLORO 2 HYDROXYPHENYL)METHYL] 5 [4 (TRIFLUOROMETHYL)PHENYL] 1,3,4 OXADIAZOLE 2(3H) ONE; 3 CHLORO 2 (2,3 DIHYDRO 2 OXO 1,3,4 OXADIAZOL 5 YL) BENZO[B] THIOPHENE; 3' [5 (4' BROMOPHENYL) 1,3,4 OXADIAZOL 2 YL] PYRIDINE; 5 (4 BIPHENYL) 3 (2 CYANOETHYL) 1,3,4 OXADIAZOL 2(3H) ONE; 5 (6,7,8,9 TETRAHYDRO 5H [1,2,4] TRIAZOLO[1,5 A] AZEPINE 2 YLMETHYLENE) 1,3,4 OXADIAZOLE 2 THIONE; 5 [4 (BENZYLOXY) PHENYL] 3 (2 CYANOETHYL) 1,3,4 OXADIAZOL 2(3H) ONE; 5 [4 (BENZYLOXY)PHENYL] 1,3,4 OXADIAZOL 2(3H) ONE; 5 ALKYL 2 ARYLSULFONAMIDO 1,3,4 OXADIAZOLE DERIVATIVE; ANTIALLERGIC AGENT; ANTIDIABETIC AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN INHIBITOR; CALCIUM ANTAGONIST; CALMODULIN INHIBITOR; COMBRETASTATIN; CYSTEINE PROTEINASE INHIBITOR; ENZYME INHIBITOR; MONOAMINE OXIDASE INHIBITOR; MONOPHENOL MONOOXYGENASE INHIBITOR; MUSCLE RELAXANT AGENT; POTASSIUM CHANNEL STIMULATING AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEASOME INHIBITOR; THIOCARBAZATE CATHEPSIN INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN RECEPTOR 2 INHIBITOR;

ANTIBACTERIAL ACTIVITY; ANTICONVULSANT ACTIVITY; ANTIDIABETIC ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIHYPERTENSIVE ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; COLORIMETRY; DRUG ACTIVITY; DRUG DESIGN; DRUG DNA BINDING; DRUG EFFICACY; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FLACCID PARALYSIS; HUMAN; IC 50; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; PHARMACODYNAMICS; REVIEW; SPASMOLYSIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTI-INFLAMMATORY AGENTS; ANTICONVULSANTS; ANTINEOPLASTIC AGENTS; DRUG DISCOVERY; ENZYME INHIBITORS; HUMANS; HYPOGLYCEMIC AGENTS; MUSCLE RELAXANTS, CENTRAL; OXADIAZOLES; PARASYMPATHOLYTICS;

EID: 84862619168     PISSN: 13895575     EISSN: 18755607     Source Type: Journal    
DOI: 10.2174/138955712801264800     Document Type: Review

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