Synthesis and antimicrobial activity of some 1,3,4-oxadiazole derivatives

Farmaco

Volumn 57, Issue 7, 2002, Pages 539-542

  Şahin, Gülay ^a   Palaska, Erhan ^a   Ekizoğlu, Melike ^a   özalp, Meral ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

1,3,4 Oxadiazole 2(3H) one; 1,3,4 Oxadiazole 2(3H) thione; 2 Amino 1,3,4 oxadiazole; Antimicrobial activity; Synthesis

Indexed keywords

ANTIINFECTIVE AGENT; OXADIAZOLE DERIVATIVE; 1 NAPHTHOL; 1,3,4 OXADIAZOLE DERIVATIVE; 2 AMINO 5 (1 NAPHTHYLOXYMETHYL) 1,3,4 OXADIAZOLE; 2 AMINO 5 (2 NAPHTHYLOXYMETHYL) 1,3,4 OXADIAZOLE; 2 NAPHTHOL; 5 (1 NAPHTHYLOXYMETHYL) 1,3,4 OXADIAZOL 2(3H) ONE; 5 (1 NAPHTHYLOXYMETHYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; 5 (2 NAPHTHYLOXYMETHYL) 1,3,4 OXADIAZOL 2(3H) ONE; 5 (2 NAPHTHYLOXYMETHYL) 1,3,4 OXADIAZOLE 2(3H) THIONE; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ESCHERICHIA COLI; MICROBIOLOGICAL EXAMINATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PSEUDOMONAS AERUGINOSA; ANTIMICROBIAL ACTIVITY; CANDIDA ALBICANS; CANDIDA KRUSEI; CANDIDA PARAPSILOSIS; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; FUNGUS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; INFRARED SPECTROSCOPY; MICROANALYSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; CANDIDA; ESCHERICHIA COLI; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; OXADIAZOLES; PSEUDOMONAS AERUGINOSA;

EID: 0037019127     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(02)01245-4     Document Type: Article

References (10)

1. Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles and -1,2,4-triazoles as orally-active, nonulcerogenic antiinflammatory agents
2. 1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: In vitro inhibition of cyclooxygenase and 5-lipoxygenase activities
3. Substituted thiosemicarbazides and corresponding cyclized 1,3,4-oxadiazoles and their anti-inflammatory activity
4. Synthesis of some new 1-acylthio-semicarbazides, 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazole-3-thiones and their anti-inflammatory activities
5. Synthesis of N-(2-naphthyloxyacetyl)thiosemicarbazides and 2-arylamino-5-(2-naphthyloxmethyl)-1,3,4-thiadiazoles/oxadiazoles as oral hypoglycemic agents
6. Studies in oxadiazoles synthesis of some 2-mercapto-1,3,4-oxadiazoles and related compounds as potential fungicides
7. Synthesis of some 5-aryl-2-heteroarylamino-1,3,4-oxadiazoles as potential fungicides
8. Synthesis of some new substituted 1,3,4-oxadiazoles as potential insecticidal, antibacterial and anti-acetylcholine esterase agents
9. Synthesis and biological activities of isoxazolo[5,4-d] pyrimidinyl-oxymethyl-thiadiazoles, -oxadiazoles and -triazoles
10. Methods for dilution antimicrobial susceptibility tests of bacteria that grow aerobically